And yet, the 1949 discovery of lithium as a cure for bipolar disorder is perhaps one of the most important—yet largely unsung—breakthroughs of the modern era. In Lithium, Walter Brown, a practicing psychiatrist and professor at Brown, reveals two unlikely success stories: that of John Cade, the physician whose discovery would come to save an untold number of lives and launch a pharmacological revolution, and that of a miraculous metal rescued from decades of stigmatization.From insulin comas and lobotomy to incarceration to exile, Brown chronicles the troubling history of the diagnosis and (often ineffective) treatment of bipolar disorder through the centuries, before the publication of a groundbreaking research paper in 1949. Cade’s “Lithium Salts in the Treatment of Psychotic Excitement” described, for the first time, lithium’s astonishing efficacy at both treating and preventing the recurrence of manic-depressive episodes, and would eventually transform the lives of patients, pharmaceutical researchers, and practicing physicians worldwide. And yet, as Brown shows, it would be decades before lithium would overcome widespread stigmatization as a dangerous substance, and the resistance from the pharmaceutical industry, which had little incentive to promote a naturally occurring drug that could not be patented.With a vivid portrait of the story’s unlikely hero, John Cade, Brown also describes a devoted naturalist who, unlike many modern medical researchers, did not benefit from prestigious research training or big funding sources (Cade’s “laboratory” was the unused pantry of an isolated mental hospital). As Brown shows, however, these humble conditions were the secret to his historic success: Cade was free to follow his own restless curiosity, rather than answer to an external funding source. As Lithium makes tragically clear, medical research—at least in America—has transformed in such a way that serendipitous discoveries like Cade’s are unlikely to occur ever again.Recently described by the New York Times as the “Cinderella” of psychiatric drugs, lithium has saved countless of lives and billions of dollars in healthcare costs. In this revelatory biography of a drug and the man who fought for its discovery, Brown crafts a captivating picture of modern medical history—revealing just how close we came to passing over this extraordinary cure.

    Marvel at the Dual Slit experiment as a tiny atom passes through 2 separate openings at the same time. Ponder the peculiar communication of quantum particles, which can remain in touch no matter how far apart. Join the genius jewel thief as he carries out a quantum measurement on a diamond without ever touching the object in question. With its clean, colorful layout and conversational tone, this text will hook you into the conundrum that is quantum mechanics.

     The Science Book covers every area of science--astronomy, biology, chemistry, geology, math, and physics, and brings the greatest scientific ideas to life with fascinating text, quirky graphics, and pithy quotes.

    Within the past ten years, however, mathematicians have proven that they hold the key to unlocking the mysteries of our world--and ourselves. In The Mathematics of Life, Ian Stewart provides a fascinating overview of the vital but little-recognized role mathematics has played in pulling back the curtain on the hidden complexities of the natural world--and how its contribution will be even more vital in the years ahead. In his characteristically clear and entertaining fashion, Stewart explains how mathematicians and biologists have come to work together on some of the most difficult scientific problems that the human race has ever tackled, including the nature and origin of life itself.

    The discovery of radium in the late 19th century prompted a flurry of experiments to scope the limits of its potential applications. Half Lives tells the fascinating, curious, sometimes macabre story of the element through its ascendance as a desirable item – a present for a queen, a prize in a treasure hunt, a glow-in-the-dark dance costume, a boon to the housewife, and an ingredient in a startling host of consumer products – to its role as a cure-all in everyday 20th-century life.Finally, it details the gradual downfall and discredit of the radium industry through the eyes of the people who bought, sold and eventually came to fear it.Half Lives is an enjoyable journey into the odd areas where science and consumerism meet, telling the tale of the entrepreneurs and consumers in radium’s history who have until now been considered quacks, or fools, or both.

    Hydrogen atoms will wriggle into your hair and betray where you live and what you have been drinking. The carbon in your breath will become tree trunks, and the sodium in your tears will link you to long-dead oceans. The nitrogen in your muscles will help to turn the sky blue, the phosphorus in your bones will help to turn the coastal waters of North Carolina green, the calcium in your teeth will crush your food between atoms that were mined by mushrooms, and the iron in your blood will kill microbes as it once killed a star.You will also discover that much of what death must inevitably do to your body is already happening among many of your atoms at this very moment and that, nonetheless, you and everyone else you know will always exist somewhere in the fabric of the universe.You are not only made of atoms; you are atoms, and this book, in essence, is an atomic field guide to yourself.

    A mojo bag is a physical representation of a spell which you can carry with you wherever you go.This book will guide you to making a bag for any intent, and includes complete instructions for the proper care and feeding of your mojo bag and exact recipes for a dozen different bags. Now Available in a Four Volume Set Magical Mojo Bags, Magical Chants, Magical Oil Recipes, and Magical Powder Recipes are now available to readers in Gianne's Grimoire of Personal Power.  Readers receive a discount purchasing the four volume set over buying each book individually.

    It's up to Sheriff Aaron Mackey to keep the peace--and keep the dregs of humanity from trying to make a killing . . .WHERE THE BULLETS FLY, VENGEANCE REIGNS If anyone can smell an investment opportunity, it's railroad men and big city bankers. They're not the kind of folks that Sheriff Mackey is used to dealing with. But greed is greed, and if anyone knows how money can drive men to murder, it's the sheriff of a boomtown like Dover Station. But when Mackey is forced to gun down a pair of saloon rats, it brings a powderkeg of trouble--with a quick-burning fuse of vengeance named Alexander Duramont. This bloodthirsty psychopath wants to kill the sheriff for killing his buddies. And he plans to get his revenge using a highly combustible mix of fire, fear, and dynamite . . . Mackey's not sure how he's going to stop this blood-crazed lunatic. But it's going to be one heck of an explosive and very violent showdown . . . "Hard to put down . . . because of the gritty and stylish narrative, the virtually nonstop action." -- Publishers Weekly on Terrence McCauley's Sympathy for the Devil

    Robert Morris chronicles the fascinating and at times frightening story of our drinking water. His gripping narrative vividly recounts the epidemics that have shaken cities and nations, the scientists who reached into the invisible and emerged with controversial truths that would save millions of lives, and the economic and political forces that opposed these researchers in a ferocious war of ideas.In the gritty world of nineteenth-century England, amid the ravages of cholera, Morris introduces John Snow, the physician who proved that the deadly disease could be hidden in a drop of water. Decades later in the deserts of Africa, the story follows Louis Pasteur and Robert Koch as they raced to find the cause of cholera and a means to prevent its spread. In the twentieth century, burgeoning cities would subdue cholera and typhoid by bending rivers to their will, building massive filtration plants, and bubbling poisonous gas through their drinking water. However, with the arrival of the new millennium, the demon of waterborne disease is threatening to reemerge, and a growing body of research has linked the chlorine relied on for water treatment with cancer and stillbirths.In The Blue Death, Morris dispels notions of fail-safe water systems. Along the way he reveals some shocking truths: the millions of miles of leaking water mains, constantly evolving microorganisms, and the looming threat of bioterrorism, which may lead to catastrophe. Across time and around the world, this riveting account offers alarming information about the natural and man-made hazards present in the very water we drink.

    Is life written into the laws of nature, or just a bizarre accident, unique in the universe? How can a mix of non-living chemicals be transformed into something as complex as the living cell? Acclaimed physicist, astrobiologist and writer Paul Davies presents evidence that life began billions of years ago kilometres underground, arguing that it may well have started on Mars and spread to Earth in rocks blasted off the Red Planet by asteroid impacts. This solution to the riddle of life's origin has sweeping implications for the nature of the universe and our place within it, and opens the way to a radical rethinking of where we came from. 'One of a handful of first-rate scientists who are popular writers. If you are going to read only one book on the origin of life, seriously consider this one'  The New York Times 'The best science writer on either side of the Atlantic'  Washington Times 'Davies succeeds not only in being provocative and controversial, but in maintaining the rigorous scientific approach of the physicist... a classic example of how to present a scientific case, and an insight into the way good scientists work'  John Gribbin, Independent Paul Davies has achieved an international reputation for his ability to explain the significance of advanced scientific ideas in simple language. He is the author of some twenty books, including Superforce, God and the New Physics, The Mind of God, The Last Three Minutes, Are We Alone? and How to Build a Time Machine.

    Those principles included modern theories of atomic and molecular structure, quantum mechanics, statistical mechanics and thermodynamics. In addition, Dr. Pauling attempted to correlate the theories with descriptive chemistry, the observed properties of substances, to introduce the student to the multitude of chemical substances and their properties.In this extensively revised and updated third edition, the Nobel prizewinning author maintains an excellent balance between theoretical and descriptive material, although the amount of descriptive chemistry has been decreased somewhat, and the presentation of the subject, especially in relation to the nonmetals, has been revised in such a way as to permit greater correlation with the electronic structure of atoms, especially electronegativity. The principles of quantum mechanics are discussed on the basis of the de Broglie wavelength of the electron. The quantized energy levels of a particle in a box are derived by means of a simple assumption about the relation of the de Broglie waves to the walls of the box. No attempt is made to solve the Schrödinger wave equation for other systems, but the wave functions of hydrogen-like electrons are presented and discussed in some detail, and the quantum states for other systems are also covered. Statistical mechanics is introduced before thermodynamics, and the discussion of thermodynamics is based on it. This arrangement reflects the author's belief that beginning students can understand statistical mechanics better than chemical thermodynamics. Aimed at first-year college students who plan to major in chemistry or closely related fields, the book is written in a logical, clear and understandable style. In addition, many excellent figures are included, along with numerous problems and 75 pages of appendixes covering such topics as symmetry of molecules and crystals, hybrid bond orbitals, and magnetic properties of substances.

    And we owe a debt to accident for some of our deepest scientific knowledge, including Newton's theory of gravitation, the Big Bang theory of Creation, and the discovery of DNA. Even the Rosetta Stone, the Dead Sea Scrolls, and the ruins of Pompeii came to light through chance. This book tells the fascinating stories of these and other discoveries and reveals how the inquisitive human mind turns accident into discovery. Written for the layman, yet scientifically accurate, this illuminating collection of anecdotes portrays invention and discovery as quintessentially human acts, due in part to curiosity, perserverance, and luck.

    There are conflicting opinions as to what should be done. Some call for dramatic increases to achieve longstanding promises. Others bang the drum for cutting it altogether, and suggest putting the fate of poor and vulnerable people in the hands of markets or business. A few argue that what is needed is creative, innovative transformation. The arguments in Aid on the Edge of Chaos are firmly in the third of these categories. In this ground-breaking book, Ben Ramalingam shows that the linear, mechanistic models and assumptions that foreign aid is built on are more at home in early twentieth century industry than in the dynamic, complex world we face today. The reality is that economies and societies are less like machines and more like ecosystems. Aid on the Edge of Chaos explores how thinkers and practitioners in economics, business, and public policy have started to embrace new, ecologically literate approaches to thinking and acting, informed by the ideas of complex adaptive systems research. It showcases insights, experiences, and dramatic results of a growing network of practitioners, researchers, and policy makers who are applying a complexity-informed approach to aid challenges. From transforming approaches to child malnutrition, to rethinking process of macroeconomic growth, from rural Vietnam to urban Columbia, Aid on the Edge of Chaos shows how embracing the ideas of complex systems thinking can help make foreign aid more relevant, more appropriate, more innovative, and more catalytic. It argues that taking on these ideas will be a vital part of the transformation of aid, from a post-WW2 mechanism of resource transfer, to a truly innovative and dynamic form of global cooperation fit for the twenty-first century.

    His contributions to our current understanding of the universe include a number of novel ideas, two of which—eternal cosmic inflation and the quantum creation of the universe from nothing—have provided a scientific foundation for the possible existence of multiple universes.With this book—his first for the general reader—Vilenkin joins another select group: the handful of first-rank scientists who are equally adept at explaining their work to nonspecialists. With engaging, well-paced storytelling, a droll sense of humor, and a generous sprinkling of helpful cartoons, he conjures up a bizarre and fascinating new worldview that—to paraphrase Niels Bohr—just might be crazy enough to be true.

    Hundreds of thousands of pianos are bought and sold each year, yet most people buy a piano with only the vaguest idea of what to look for as they make this major purchase. The Piano Book evaluates and compares every brand and style of piano sold in the United States. There is information on piano moving and storage, inspecting individual new and used pianos, the special market for Steinways, and sales gimmicks to watch out for. An annual supplement, sold separately, lists current prices for more than 2,500 new piano models.