gross domestic product by 2020. In Drugs for Life, Joseph Dumit considers how our burgeoning consumption of medicine and cost of healthcare not only came to be, but also came to be taken for granted. For several years, Dumit attended pharmaceutical industry conferences; spoke with marketers, researchers, doctors, and patients; and surveyed the industry's literature regarding strategies to expand markets for prescription drugs. He concluded that underlying the continual growth in medications, disease categories, costs, and insecurity is a relatively new perception of ourselves as inherently ill and in need of chronic treatment. This perception is based on clinical trials that we have largely outsourced to pharmaceutical companies. Those companies in turn see clinical trials as investments and measure the value of those investments by the size of the market and profits that they will create. They only ask questions for which the answer is more medicine. Drugs for Life challenges our understanding of health, risks, facts, and clinical trials, the very concepts used by pharmaceutical companies to grow markets to the point where almost no one can imagine a life without prescription drugs.

    He seemed pointed toward stardom, but would it be in basketball, his true favorite, or maybe in track, where he qualified for the 2008 U.S. Olympic Trials as a hurdler? As for playing football, the only sport that really mattered in Griffin’s small Texas town, first he had to overcome his mother’s objections to the violence and danger—which he did by making a “Pinkie Promise” with her that no one would catch him. Eventually, he began to realize that all of his remarkable talents—unrivaled speed, pinpoint accuracy, exceptional intelligence, single-minded drive—combined into a potent force that few quarterbacks could rival. What followed seemed almost destined: a football scholarship to Baylor University, three exceptional seasons capped by winning the Heisman Trophy, and the 2012 draft—where Griffin, as the second overall pick, became the franchise quarterback for one of the oldest and most storied football teams in the country.In RG3: The Promise, Washington Post reporter Dave Sheinin provides an in-depth, behind-the-scenes look at Griffin’s first year in the NFL, from his record-breaking first game to the frightening knee injury that ended the Redskins’ playoff hopes. An award-winning journalist himself, Sheinin has reported on Griffin’s rookie season every step of the way, and now has written a unique, intimate look inside the transformation of one of the NFL’s brightest young stars.

    The format makes learning easy with short, easy-to-read chapters, color tables, key point summaries, and review questions in every chapter. You'll get the latest coverage on regulatory T cells, biology of the Th17 subset of CD4+ T cells, and more. The full-color artwork, comprehensive glossary, and clinical cases are just some of the features that reinforce and test your understanding of how the immune system functions. Student Consult online access lets you search the full text online and pursue further study through integration links. Covers the most up-to-date immunology information including regulatory T cells, and biology of the Th17 subset of CD4+ T cells to keep you completely current. Features integration links through included STUDENT CONSULT access for more in-depth study. Relates basic science to clinical disorders through clinical cases for better application in a real-world setting. Provides a full Glossary to keep you on the cutting edge of immunologic terminology. Includes appendices summarizing the features of CD Molecules, a handy Glossary, and Clinical Cases that test your understanding of how the immune system functions in health and disease. Presents beautiful full-color artwork for enhanced visual learning.

    The book also includes a chapter on clinical pharmacology (which alone accounts for up to 30% of the questions), looking at aspects of drug-induced disease and drug interactions. Finally there is a chapter on statistics and epidemiology which is rarely covered in other texts, but is often included in the exam.Helps MRCP Part 1 candidates prepare for and pass their exam.Addresses an increasingly important topic in the exam.Addresses a topic that is vital to passing the exam, but which most candidates are poorly prepared for.Covers all the relevant basic science subjects plus includes clinical pharmacology.Is of use to candidates studying for other postgraduate exams such as PLAB, USMLE and MRCPCH.Is the first book of its kind in the membership market and is now regarded as essential for exam preparation.

    But it's not, perhaps, the story you expect.Gavin Francis is a GP who works in both urban and rural communities, splitting his time between Edinburgh and the islands of Orkney. When the pandemic ripped through our society he saw how it affected every walk of life: the anxious teenager, the isolated care home resident, the struggling furloughed worker and homeless ex-prisoner, all united by their vulnerability in the face of a global disaster. And he saw how the true cost of the virus was measured not just in infections, or deaths, or ITU beds, but in the consequences of the measures taken against it.In this deeply personal account of nine months spent caring for a society in crisis, Francis will take you from rural village streets to local clinics and communal city stairways. And in telling this story, he reveals others: of loneliness and hope, illness and recovery, and of what we can achieve when we care for each other.

    Progressing logically from a molecular understanding of receptors and drug actions to the clinical uses of the most important groups of drugs, it delivers the latest information on cannabinoids and rimonabant, Cox 2 inhibitors, pharmacogenetics, biopharmaceuticals, and drug abuse-as well as "lifestyle drugs" such as performance-enhancing substances, botulinum toxin, and Viagra?. And now, online access via STUDENT CONSULT makes it an even more effective learning resource

    This edition provides increased coverage of taste and smell, circadian rhythms, brain development, and developmental disorders and includes new information on molecular mechanisms and functional brain imaging. Path of Discovery boxes, written by leading researchers, highlight major current discoveries. In addition, readers will be able to assess their knowledge of neuroanatomy with the Illustrated Guide to Human Neuroanatomy, which includes a perforated self-testing workbook.This edition's robust ancillary package includes a bound-in student CD-ROM, an Instructor's Resource CD-ROM, and resources online.

    Now she had everything she wanted—until the nightmare began at Morton General Hospital.THE CRIMELicensed practical nurse Anne Capute administered a fatal dose of morphine to a dying patient, Norma Leanues. Anne claimed she was following common practice at Morton General, with a verbal approval by Dr. Hillier, to administer unrestricted doses of morphine as a humane antidote to the unbearable suffering of terminal cases.THE CHARGEOne day after the death of Mrs. Leanues, Dr. Hillier was off on a European vacation, and Anne Capute was suspended. Three days later she was advised to retain a lawyer—she would be standing trial for first degree murder.THE TRIALOne after another, doctors and nurses with whom Anne had worked so closely testified against her. And the most damaging prosecution witness of all was Dr. Hillier. Suddenly Anne’s life’s dream was destroyed. And as her personal life, too, began to shatter, there remained little hope of acquittal—or justice.Anne Capute: A woman on trial for her life. One dedicated nurse battling against the vast influence of the medical establishment. Hers is a true story of courage, drama, and penetrating suspense that no reader will soon forget.

    The 2019 offering from Welcome to the Museum guides readers through the human body, from the muscles we use to show emotion, to the delicate workings of the brain. With sumptuous artwork by Katy Wiedemann and expert text by professor Dr Jennifer Z Paxton, this beautiful book is a feast of anatomical knowledge.

    The chilling words are followed by a confession to a murder committed nearly 13 years earlier. The chance discovery of the letter on 31 March 2012 reawakens a case long considered to have run cold, and a hunt begins for the men who kidnapped and killed Betty Ketani – and were convinced they had gotten away with it. The investigation spans five countries, with a world-renowned DNA laboratory called in to help solve the forensic puzzle. The author of the confession letter might have feared death, but he is very much alive, as are others implicated in the crime.Betty Ketani, a mother of three, came to Johannesburg in search of better prospects for her family. She found work cooking at one of the city’s most popular restaurants, and then one day she mysteriously disappeared. Those out to avenge her death want to bring closure to Betty’s family, still agonising over her fate all these years later.The storyline would not be out of place as a Hollywood movie – and it’s all completely true. Written by the reporter who broke the story, Cold Case Confession goes behind the headlines to share exclusive material gathered in four years of investigations, including the most elusive piece of the puzzle: who would want Betty Ketani dead, and why?‘Wonderful, evocative and vivid writing. Eliseev is a very exciting new talent.’ – Peter James‘This case is like an Agatha Christie whodunnit: abduction, murder and a confession.’ – Carte Blanche‘A relentless search for truth and justice. Cold Case Confession is a story that inspires confidence in the system and affirms that, indeed, we are all equal before the law.’ – Thuli Madonsela

    

    Viruses are disarmingly small and simple. Nevertheless, the smallpox virus killed over 300 million people in the twentieth century before it was eradicated in 1980. The AIDSvirus, HIV, is now the world's biggest killer infection and the single most common cause of death in Africa. In recent years, the outbreaks of several lethal viruses such as Ebola and Hantavirus have caused great public concern--yet most people remain woefully ill-informed.In this fascinating new book, Dorothy Crawford explains lucidly and accessibly all aspects of the natural history of these deadly parasites and discusses controversial subjects such as CFS and Gulf War Syndrome. The book considers issues such as how man has coped with viruses in the past, where newviruses come from, and whether it would be possible for a new virus to wipe out the human race. Professor Crawford illustrates her arguments with vivid and wide-ranging examples. The result is an informative and highly readable book, which will be read by all those who seek a deeper understanding ofthese minute but remarkably efficient killers.

    We have all benefited from the medical discoveries of primate research--vaccines for polio, rubella, and hepatitis B are just a few. But we have also learned more in recent years about how intelligent apes and monkeys really are: they can speak to us with sign language, they can even play video games (and are as obsessed with the games as any human teenager). And activists have also uncovered widespread and unnecessarily callous treatment of animals by researchers (in 1982, a Silver Spring lab was charged with 17 counts of animal cruelty). It is a complex issue, made more difficult by the combative stance of both researchers and animal activists. In The Monkey Wars, Deborah Blum gives a human face to this often caustic debate--and an all-but-human face to the subjects of the struggle, the chimpanzees and monkeys themselves. Blum criss-crosses America to show us first hand the issues and personalities involved. She offers a wide-ranging, informative look at animal rights activists, now numbering some twelve million, from the moderate Animal Welfare Institute to the highly radical Animal Liberation Front (a group destructive enough to be placed on the FBI's terrorist list). And she interviews a wide variety of researchers, many forced to conduct their work protected by barbed wire and alarm systems, men and women for whom death threats and hate mail are common. She takes us to Roger Fouts's research center in Ellensburg, Washington, where we meet five chimpanzees trained in human sign language, and we visit LEMSIP, a research facility in New York State that has no barbed wire, no alarms--and no protesters chanting outside--because its director, Jan Moor-Jankowski, listens to activists with respect and treats his animals humanely. And along the way, Blum offers us insights into the many side-issues involved: the intense battle to win over school kids fought by both sides, and the danger of transplanting animal organs into humans. As it stands now, Blum concludes, the research community and its activist critics are like two different nations, nations locked in a long, bitter, seemingly intractable political standoff....But if you listen hard, there really are people on both sides willing to accept and work within the complex middle. When they can be freely heard, then we will have progressed to another place, beyond this time of hostilities. In The Monkey Wars, Deborah Blum gives these people their voice.

    Its full-colour illustration program includes many novel, visually effective features to help students learn.

    In this essential guide, Bruce Rogers, "The Orchid Whisperer," shares his expert tips from more than three decades of breeding and growing orchids. The book demystifies the growing process and features more than 100 lush color photographs of breathtaking plants. Best of all, it reveals professional secrets not found anywhere else for blooming, repotting, spotting hazards and pests, grooming, decorating, and much more. Perfect for beginners as well as orchid experts looking for new tricks, The Orchid Whisperer provides everything readers need to know to keep healthy orchids that will flower again and again!