If you use Python, even as a beginner, this book will teach you practical ways to build your own machine learning solutions. With all the data available today, machine learning applications are limited only by your imagination.You'll learn the steps necessary to create a successful machine-learning application with Python and the scikit-learn library. Authors Andreas Muller and Sarah Guido focus on the practical aspects of using machine learning algorithms, rather than the math behind them. Familiarity with the NumPy and matplotlib libraries will help you get even more from this book.With this book, you'll learn:Fundamental concepts and applications of machine learningAdvantages and shortcomings of widely used machine learning algorithmsHow to represent data processed by machine learning, including which data aspects to focus onAdvanced methods for model evaluation and parameter tuningThe concept of pipelines for chaining models and encapsulating your workflowMethods for working with text data, including text-specific processing techniquesSuggestions for improving your machine learning and data science skills

    With fewer people and resources than any of the top competitors, the only way they were going to win was to push the limit, go for broke, and hope for more than a little luck. By the time they got to the racetrack, they knew: In the fog of fierce competition, whether you win or lose, you learn the hardest lessons about engineering, teamwork, friendship, and yourself.

    The Eighth Edition has been thoroughly revised and updated and is available in both print and e-book formats.Janeway s Immunobiology continues to set the standard for currency and authority with its clear writing style and organization, uniform art program, and scientific accuracy. It presents a consistent point of view throughout that of the host s interaction with an environment containing many species of potentially harmful microorganisms. The full-color art program is conceptually coherent and illustrates the processes and mechanisms underlying the concepts in the text. The 16 chapters in this readable, accessible textbook are organized and presented in such a way as to help deliver a complete one-semester immunology course, beginning with innate immunity, then moving to adaptive immunity, and ending with applied clinical immunology.Discussion questions are provided at the end of Chapters 2 to 16. These questions can be used for review, or as the basis for discussion in class or in informal study groups. Summaries conclude each section and each chapter. As in previous editions, a caduceus icon in the margins indicates topics which are correlated to Case Studies in Immunology, Sixth Edition by Geha and Notarangelo.New in the Eighth EditionInnate immunity has been updated and expanded and is now presented in two separate chapters (Chapters 2 and 3), as well as being further emphasized in the rest of the textbook. Chapter 2 covers antimicrobial peptides and the complement system, and Chapter 3 deals with cellular innate receptors and cell-mediated innate immunity (e.g. TLRs, phagocytosis, NK cells, interferon production, innate-like lymphocytes). The section on complement has been reworked and reconceived explaining the lectin pathway first making it easier to teach by placing it into the context of innate recognition. Evolution is now incorporated throughout the text, helping students see similar strategies used by different organisms. The text and figures of Chapter 7 Signaling Through Immune System Receptors have been revised to present a cohesive synthesis of signaling for immunology, focusing on improved illustration of antigen recognition signaling and lymphocyte activation. Signaling through other receptors is dealt with wherever appropriate throughout the book. Updated chapter on B-cell immune responses (Chapter 10), especially on trafficking of B cells in peripheral lymphoid organs (e.g. lymph nodes) and the locations at which they encounter antigen. Coverage of mucosal immunity (Chapter 12) has been brought up to date, including responses to the commensal microbiota and the role of specialized dendritic cells and the regulatory T cells in maintaining tolerance to food antigens and commensal bacteria. Chapter 13, Failures of Host Defense Mechanisms, has been reorganized and revised to structure an understanding of primary immunodeficiencies in the context of developmental pathways. Chapter 16, Manipulation of the Immune Response, has been heavily revised to include a greater emphasis on clinical issues and a complete update of immunotherapeutics and vaccines. Many new and revised figures illustrate the processes and mechanisms underlying the concepts presented in the text. The icons used have been updated and expanded to incorporate a new emphasis on signaling pathways. New references have been added throughout the text.

    Chapters cover cancer, infection, immune disorders, genetics, and disorders of each body system, highlighting pathophysiologic processes, resulting signs and symptoms, diagnostic test findings, and current treatments. Reader-friendly features include illustrations, checklists, and full-color miniguides illustrating the pathophysiology of specific disorders.This edition has new full-color miniguides on cancer pathophysiology and neuropathology. A new Focus on Genetics feature identifies gene-related discoveries and their implications for treatment or diagnosis. Review questions and answers follow current NCLEX-RN® requirements and alternate-format questions are included.

    John Arnold's addition to Oxford's popular Very Short Introductions series is a stimulating essay about how people studyand understand history. The book begins by inviting us to think about various questions provoked by our investigation of history, and then explores the ways in which these questions have been answered in the past. Such key concepts as causation, interpretation, and periodization are introduced byway of concrete examples of how historians work, thus giving the reader a sense of the excitement implicit in discovering the past--and ourselves.The aim throughout History: A Very Short Introduction is to discuss theories of history in a general, pithy, and accessible manner, rather than delve into specific periods. This is a book that will appeal to all students and general readers with an interest in history or historiography.About the Series: Oxford's Very Short Introductions series offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, Literary Theory to History, and Archaeology to the Bible. Not simply a textbook of definitions, each volume in this series provides trenchantand provocative--yet always balanced and complete--discussions of the central issues in a given discipline or field. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how the subject has developed and how it has influenced society. Eventually, theseries will encompass every major academic discipline, offering all students an accessible and abundant reference library. Whatever the area of study that one deems important or appealing, whatever the topic that fascinates the general reader, the Very Short Introductions series has a handy andaffordable guide that will likely prove indispensable.

    All chapters in this best-seller have been substantially revised to reflect recent discoveries and new understanding of linguistics and languages.

    Some of the objects are described by future historians; others through found materials, short stories, or dialogues. All come from a very real future.

    It's goal is the successful design and operation of chemical reactors. This text emphasizes qualitative arguments, simple design methods, graphical procedures, and frequent comparison of capabilities of the major reactor types. Simple ideas are treated first, and are then extended to the more complex.

    With cases studies found throughout, you will easily learn to apply principles to real life.

    The guide includes information on aspects of the search that are common to all levels, with invaluable tips for those seeking their first or second faculty position. This new edition provides updated advice and addresses hot topics in the competitive job market of today, including the challenges faced by dual-career couples, job search issues for pregnant candidates, and advice on how to deal with gaps in a CV. The chapter on alternatives to academic jobs has been expanded, and sample resumes from individuals seeking nonfaculty positions are included.The book begins with an overview of the hiring process and a timetable for applying for academic positions. It then gives detailed information on application materials, interviewing, negotiating job offers, and starting the new job. Guidance throughout is aimed at all candidates, with frequent reference to the specifics of job searches in scientific and technical fields as well as those in the humanities and social sciences. Advice on seeking postdoctoral opportunities is also included.Perhaps the most significant contribution is the inclusion of sample vitas. "The Academic Job Search Handbook" describes the organization and content of the vita and includes samples from a variety of fields. In addition to CVs and research statements, new in this edition are a sample interview itinerary, a teaching portfolio, and a sample offer letter. The job search correspondence section has also been updated, and there is current information on Internet search methods and useful websites.

    With a balanced blend of case excerpts and author commentary, Samaha guides you as you hone your critical thinking and legal analysis skills. You'll see the principles, defenses, and elements of crime at work as you progress through the book-and you'll learn about the general principles of criminal liability and its defenses, as well as the elements of crimes against persons property, society, and crimes against the state. Featuring the latest topics and court cases, as well as many study tools to help you do well in this course, Samaha's CRIMINAL LAW is a text you will want to keep as a valuable reference even after you graduate and begin your career in the criminal justice field of your choosing.

    A rich source of information for readers of all ages, this book is divided into two sections, first looking at major sources of symbols (basic shapes, colors and numbers, the natural world), then, placing symbols in context of mythologies and religions, the human life cycle, people and culture, and symbol systems. Clear cross-referencing illuminates connections between symbols, while beautiful artwork and photography make this a collector's edition to treasure.

    Musicians of this genre have developed an often impenetrable sound that teeters on the edge of screaming, incomprehensible noise. Extreme metal circulates on the edge of mainstream culture within the confines of an obscure 'scene', in which members explore dangerous themes such as death, war and the occult, sometimes embracing violence, neo-fascism and Satanism. In the first book-length study of extreme metal, Keith Kahn-Harris draws on first-hand research to explore the global extreme metal scene. He shows how the scene is a space in which members creatively explore destructive themes, but also a space in which members experience the everyday pleasures of community and friendship. Including interviews with band members and fans, from countries ranging from the UK and US to Israel and Sweden, Extreme Metal: Music and Culture on the Edge demonstrates the power and subtlety of an often surprising and misunderstood musical form.

    Belknap's Waterproof Grand Canyon River Guide (All New Color Edition)

    The book begins with a framework elucidating the transactions between individual development and the child's wider environment, and emphasizing the crucial role of attachment. Key developmental processes and tasks from infancy through middle childhood are then discussed in paired chapters that respectively address how children of different ages typically feel, think, and behave, and how to intervene effectively with those who are having difficulties.