Is the apple sitting on your kitchen counter alive, or is only the apple tree it came from deserving of the word? If we can't answer that question here on earth, how will we know when and if we discover alien life on other worlds? The question hangs over some of society's most charged conflicts--whether a fertilized egg is a living person, for example, and when we ought to declare a person legally dead.Charting the obsession with Dr. Frankenstein's monster and how Coleridge came to believe the whole universe was alive, Zimmer leads us all the way into the labs and minds of researchers working on engineering life from the ground up.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    Based on her work at the Santa Fe Institute and drawing on its interdisciplinary strategies, Mitchell brings clarity to the workings of complexity across a broad range of biological, technological, and social phenomena, seeking out the general principles or laws that apply to all of them. Richly illustrated, Complexity: A Guided Tour--winner of the 2010 Phi Beta Kappa Book Award in Science--offers a wide-ranging overview of the ideas underlying complex systems science, the current research at the forefront of this field, and the prospects for its contribution to solving some of the most important scientific questions of our time.

    Based on the most massive study of human mating ever undertaken, encompassing more than 10,000 people of all ages from thirty-seven cultures worldwide, The Evolution of Desire is the first book to present a unified theory of human mating behavior.Now in an updated edition with two new chapters by the author, The Evolution of Desire presents the latest research in the field, including starting new discoveries about the evolutionary advantages of infidelity, orgasm, and physical attractiveness.

    He tells of the large science-steeped family who fostered his early fascination with chemistry. There follow his years at boarding school where, though unhappy, he developed the intellectual curiosity that would shape his later life. And we hear of his return to London, an emotionally bereft ten-year-old who found solace in his passion for learning. Uncle Tungsten radiates all the delight and wonder of a boy’s adventures, and is an unforgettable portrait of an extraordinary young mind.

    Albert-László Barabási, the nation’s foremost expert in the new science of networks and author of Bursts, takes us on an intellectual adventure to prove that social networks, corporations, and living organisms are more similar than previously thought. Grasping a full understanding of network science will someday allow us to design blue-chip businesses, stop the outbreak of deadly diseases, and influence the exchange of ideas and information. Just as James Gleick and the Erdos–Rényi model brought the discovery of chaos theory to the general public, Linked tells the story of the true science of the future and of experiments in statistical mechanics on the internet, all vital parts of what would eventually be called the Barabási–Albert model.

    Anthony Brandt and David Eagleman rifle through the inventions of human society like paleontologists ransacking the fossil record. Exploring examples from Apollo 13 to Pablo Picasso, they seek to answer the question: what lies at the heart of humanity's ability--and drive--to create? If you took a snapshot of any animal species' behavior, from apes to barnacles, and contrasted it with the same species 10,000 years ago, they'd all be carrying on pretty much as usual (and if they aren't, it's likely due to human influence). Humanity, on the other hand, would be nearly unrecognizable. Above all else, our drive to create is what makes us unique among all living things. Yet where does this all creation, innovation, and change come from? Why us? And if we better understand this -cognitive software-, can we harness it more responsibly to improve our lives, schools, businesses and institutions? Brandt and Eagleman examine hundreds of examples of human creativity through dramatic storytelling and stunning images in this beautiful, full-color volume. By drawing out what creative acts have in common and viewing them through the lens of cutting-edge neuroscience, they uncover the essential elements of this critical human ability, and encourage a more creative future for all of us.

    Cavalli-Sforza and others have answered this question—anticipated by Darwin—with a decisive yes. Genes, Peoples, and Languages comprises five lectures that serve as a summation of the author's work over several decades, the goal of which has been nothing less than tracking the past hundred thousand years of human evolution.Cavalli-Sforza raises questions that have serious political, social, and scientific import: When and where did we evolve? How have human societies spread across the continents? How have cultural innovations affected the growth and spread of populations? What is the connection between genes and languages? Always provocative and often astonishing, Cavalli-Sforza explains why there is no genetic basis for racial classification.

    While some books explore our genetic inheritance and popular television shows celebrate ancestry, this is the first book to explore how everything from DNA to emotions to names and the stories that form our lives are all part of our human legacy. This book shows how trust is inherited in Africa, silence is passed down in Tasmania, and how the history of nations is written in our DNA. From fateful, ancient encounters to modern mass migrations and medical diagnoses, Kenneally explains how the forces that shaped the history of the world ultimately shape each human who inhabits it. The Invisible History of the Human Race is a deeply researched, carefully crafted, and provocative perspective on how our stories, psychology, and genetics affect our past and our future.

    Humans have "subdued 75 per cent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness." We now collect the DNA of vanishing species in a "frozen ark," equip orangutans with iPads, create wearable technologies and synthetic species that might one day outsmart us. With her distinctive gift for making scientific discovery intelligible to the layperson, Ackerman takes us on an exciting journey to understand this bewildering new reality, introducing us to many of the people and ideas now creating--perhaps saving--the future.The Human Ageis a surprising, optimistic engagement with the dramatic transformations that have shaped, and continue to alter, our world, our relationship with nature and our prospects for the future.

    The knowledge and fear of the existence of these ferocious man-eaters is forever in the back of our minds, looming in our worst nightmares. Millions of humans have suffered attacks by predators on land and at sea. Yet animals have always shared the landscape with humans. Since the dawn of time our ecosystems have been linked and humans have co-existed with flesh-eating beasts as members of the same food chain. Now, of course, as humans spread and despoil the planet, these fearsome predators may only survive on the other side of glass barriers and chain-link fences. Their gradual disappearance is changing the nature of our own existence. We no longer occupy an intermediate position on the food chain; instead we survey it invulnerably from above - so far above that we are in danger of forgetting that we even belong to an ecosystem.David Quammen's enthralling new book covers the four corners of the globe as he explores the fate of lions in India's Gir forest, saltwater crocodiles in Northern Australia, brown bears in the mountains of Romania, and Siberian tigers. Tracking these great and terrible beasts through the toughest terrain in the world, Quammen is equally intrigued by the traditional relationship between the great predators and the people who live among them, and weaves into his story the fears and myths that have haunted humankind for 3000 years.

    It shows how political orientations across space and time arise from three clusters of measurable personality traits. These clusters entail opposing attitudes toward tribalism, inequality, and differing perceptions of human nature. Together, these traits are by far the most powerful cause of left-right voting, even leading people to regularly vote against their economic interests.      As this book explains, our political personalities also influence our likely choice of a mate, and shape society's larger reproductive patterns. Most importantly of all, it tells the evolutionary stories of these crucial personality traits, which stem from epic biological conflicts.     Based on dozens of exciting new insights from primatology, genetics, neuroscience, and anthropology, this groundbreaking work brings core concepts to life through current news stories and personalities. For instance, readers will meet Glenn Beck and Hugo Chavez and come to understand the underlying evolutionary forces they represent. By blending serious research with relevant contemporary examples, Our Political Nature casts important light onto the ideological clashes that so dangerously divide and imperil our world today.

    In Self Comes to Mind, he goes against the long-standing idea that consciousness is somehow separate from the body, presenting compelling new scientific evidence that consciousness—what we think of as a mind with a self—is to begin with a biological process created by a living organism. Besides the three traditional perspectives used to study the mind (the introspective, the behavioral, and the neurological), Damasio introduces an evolutionary perspective that entails a radical change in the way the history of conscious minds is viewed and told. He also advances a radical hypothesis regarding the origins and varieties of feelings, which is central to his framework for the biological construction of consciousness: feelings are grounded in a near fusion of body and brain networks, and first emerge from the historically old and humble brain stem rather than from the modern cerebral cortex.  Damasio suggests that the brain’s development of a human self becomes a challenge to nature’s indifference and opens the way for the appearance of culture, a radical break in the course of evolution and the source of a new level of life regulation—sociocultural homeostasis. He leaves no doubt that the blueprint for the work-in-progress he calls sociocultural homeostasis is the genetically well-established basic homeostasis, the curator of value that has been present in simple life-forms for billions of years. Self Comes to Mind is a groundbreaking journey into the neurobiological foundations of mind and self.Downloadhttp://depositfiles.com/files/xlt08paxhOrhttp://www.filesonic.com/file/3554828...

    Wilczek’s groundbreaking work in quantum physics was inspired by his intuition to look for a deeper order of beauty in nature. In fact, every major advance in his career came from this intuition: to assume that the universe embodies beautiful forms, forms whose hallmarks are symmetry—harmony, balance, proportion—and economy. There are other meanings of “beauty,” but this is the deep logic of the universe—and it is no accident that it is also at the heart of what we find aesthetically pleasing and inspiring.Wilczek is hardly alone among great scientists in charting his course using beauty as his compass. As he reveals in A Beautiful Question, this has been the heart of scientific pursuit from Pythagoras, the ancient Greek who was the first to argue that “all things are number,” to Galileo, Newton, Maxwell, Einstein, and into the deep waters of twentiethcentury physics. Though the ancients weren’t right about everything, their ardent belief in the music of the spheres has proved true down to the quantum level. Indeed, Wilczek explores just how intertwined our ideas about beauty and art are with our scientific understanding of the cosmos.Wilczek brings us right to the edge of knowledge today, where the core insights of even the craziest quantum ideas apply principles we all understand. The equations for atoms and light are almost literally the same equations that govern musical instruments and sound; the subatomic particles that are responsible for most of our mass are determined by simple geometric symmetries. The universe itself, suggests Wilczek, seems to want to embody beautiful and elegant forms. Perhaps this force is the pure elegance of numbers, perhaps the work of a higher being, or somewhere between. Either way, we don’t depart from the infinite and infinitesimal after all; we’re profoundly connected to them, and we connect them. When we find that our sense of beauty is realized in the physical world, we are discovering something about the world, but also something about ourselves.Gorgeously illustrated, A Beautiful Question is a mind-shifting book that braids the age-old quest for beauty and the age-old quest for truth into a thrilling synthesis. It is a dazzling and important work from one of our best thinkers, whose humor and infectious sense of wonder animate every page. Yes: The world is a work of art, and its deepest truths are ones we already feel, as if they were somehow written in our souls.

    Penetrating, gripping, and provocative, this book combines natural history, anthropology, and ecology on an epic scale. Illustrations.