He shows how oxygen underpins the origin of biological complexity, the birth of photosynthesis, the sudden evolution of animals, the need for two sexes, the accelerated aging of cloned animals like Dolly the sheep, and the surprisingly long lives of bats and birds. Drawing on this grand evolutionary canvas, Oxygen offers fresh perspectives on our own lives and deaths, explaining modern killer diseases, why we age, and what we can do about it. Advancing revelatory new ideas, following chains of evidence, the book ranges through many disciplines, from environmental sciences to molecular medicine. The result is a captivating vision of contemporary science and a humane synthesis of our place in nature. This remarkable book will redefine the way we think about the world.

    The culprit--so necessary and yet the source of such upheaval--is the X chromosome, and this is its story. An enlightening and entertaining tour of the cultural and natural history of this intriguing member of the genome, "The X in Sex" traces the journey toward our current understanding of the nature of X. From its chance discovery in the nineteenth century to the promise and implications of ongoing research, David Bainbridge shows how the X evolved and where it and its counterpart Y are going, how it helps assign developing human babies their sex--and maybe even their sexuality--and how it affects our lives in infinitely complex and subtle ways. X offers cures for disease, challenges our cultural, ethical, and scientific assumptions about maleness and femaleness, and has even reshaped our views of human evolution and human nature.

    Pairing Charles Darwin and a rare species of barnacle as her unlikely protagonists, Rebecca Stott has written an absorbing work of history that guides readers through the treacherous shoals of nineteenth-century biology. Beginning her scientific detective story in the 1820s, even before Darwin's Beagle voyage, Stott examines the mystery of why Darwin waited over two decades between formulating his pivotal theory of natural selection and publishing it. Lavishly illustrated, filled with riddles and concepts that challenge our notion of Victorian science, Darwin and the Barnacle is a thrilling account of how genius proceeds through indirection—and how one small item of curiosity contributed to history's most spectacular scientific breakthrough.

    David Grinspoon, a planetary scientist who has helped to shape modern planetary exploration, brings the subject to a new generation of readers with his reflections on the most recent developments in astrobiology, including NASA's search for life on Mars. In Lonely Planets, he investigates the big questions: How widespread are life and intelligence in the cosmos? Is life on Earth an accident or in some sense the "purpose" of this universe? And how can we, working from the Earth-centric definition of "life," even begin to think about the varieties of life-forms on other planets?Using the topic of extraterrestrial life as a mirror with which to view human beliefs, evolution, history, and aspirations, Grinspoon provides an authoritative scientific narrative of cosmic evolution, along with provocative ruminations on how we fit into the story of the universe. An accessible, lively blend of science, history, philosophy, and personal narrative, Lonely Planets reveals how the search for extraterrestrial life unites our spiritual and scientific quests for connection with the cosmos.

    People knew the basics: men and women had sex, and sometimes babies followed. But beyond that the origins of life were a colossal mystery. The Seeds of Life is the remarkable and rollicking story of how a series of blundering geniuses and brilliant amateurs struggled for two centuries to discover where, exactly, babies come from. Taking a page from investigative thrillers, acclaimed science writer Edward Dolnick looks to these early scientists as if they were detectives hot on the trail of a bedeviling and urgent mystery. These strange searchers included an Italian surgeon using shark teeth to prove that female reproductive organs were not 'failed' male genitalia, and a Catholic priest who designed ingenious miniature pants to prove that frogs required semen to fertilize their eggs. A witty and rousing history of science, The Seeds of Life presents our greatest scientists struggling-against their perceptions, their religious beliefs, and their deep-seated prejudices-to uncover how and where we come from.

    Cave paintings of the giant beasts hint at the profound role they played in early human culture-our Ice Age ancestors built igloo-shaped huts out of mammoth bones and even feasted on mammoth tongues. Eager to uncover more clues to this mystical prehistoric age, explorers since the time of Peter the Great have scoured Siberia for mammoth remains. Now a new generation of explorers has taken to the tundra. Armed with GPS, ground-penetrating radar, and Soviet-era military helicopters, they seek an elusive prize: a mammoth carcass that will help determine how the creature lived, how it died-and how it might be brought back to life.In this adventure-filled narrative, science writer Richard Stone follows two teams of explorers-one Russian/Japanese, the other a French-led consortium-as they battle bitter cold, high winds, supply shortages, and the deeply rooted superstitions of indigenous peoples who fear the consequences of awakening the "rat beneath the ice." Stone travels from St. Petersburg to the Arctic Circle, from the North Sea to high-tech Japanese laboratories, as he traces the sometimes-surreal quest of these intrepid scientists, whose work could well rewrite our planet's evolutionary history. A riveting tale of high-stakes adventure and scientific hubris, Mammoth is also an intellectual voyage through uncharted moral terrain, as we confront the promise and peril of resurrecting creatures from the deep past.

    Instead, ants decide what to do based on the rate, rhythm, and pattern of individual encounters and interactions--resulting in a dynamic network that coordinates the functions of the colony. Ant Encounters provides a revealing and accessible look into ant behavior from this complex systems perspective.Focusing on the moment-to-moment behavior of ant colonies, Deborah Gordon investigates the role of interaction networks in regulating colony behavior and relations among ant colonies. She shows how ant behavior within and between colonies arises from local interactions of individuals, and how interaction networks develop as a colony grows older and larger. The more rapidly ants react to their encounters, the more sensitively the entire colony responds to changing conditions. Gordon explores whether such reactive networks help a colony to survive and reproduce, how natural selection shapes colony networks, and how these structures compare to other analogous complex systems. Ant Encounters sheds light on the organizational behavior, ecology, and evolution of these diverse and ubiquitous social insects.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    In The Missing Lynx, Ross Barnett uses case studies, new fossil discoveries, biomolecular evidence and more to paint pictures of these extinct species, and to explore the significance of the lynx's disappearance in ecological terms. He also discusses how the Britons that these animals shared their home with might have viewed them, and why some survived while others vanished.Barnett also looks in detail and the realistic potential of reintroductions and even of resurrection--topics that capture public interest today. With Beaver now wild again in various parts of Britain and even Great Bustard on Salisbury Plain, what about the return of sabretooths, mammoths, and the aurochs to modern ecosystems? Will we ever be able to bring these animals back? And should we?At a time where rewilding is moving from pie-in-the-sky to actual reality, this timely and important book looks from a scientific perspective at the magnificent megafauna we've lost, why we lost it and what happened as a result, and how we might realistically turn the ecological tide.

    And many people who support the teaching of evolution—students, teachers, parents, administrators—do not have the background to respond. They know that scientists have thoroughly dismantled these arguments, but they don't have a handy way of responding to these attacks. The Counter-Creationism Handbook is a one-stop resource for addressing over 400 of the most prevalent claims made by creationists. Each claim is followed by a succinct and scientifically valid rebuttal, and the book includes print and on-line resources for further reading and information. The Counter-Creationism Handbook:* Covers claims made about the disciplines of philosophy, biology, paleontology, geology, astronomy, physics and mathematics, history, and more.* Addresses the claims of Biblical creationism, intelligent design creationism, and some creationism based on non-Christian religions.* Includes an introduction on how to address creationists in different venues, how to deal with novel claims, and why accurate science is important.* Is organized thematically, with extensive cross-referencing.

    Thanks to cartoons and folk accounts we have a distorted view of these other humans - for that is what they were. We think of them as crude and clumsy and not very bright, easily driven to extinction by the lithe, smart modern humans that came out of Africa some 100,000 years ago.But was it really as simple as that? Clive Finlayson reminds us that the Neanderthals were another kind of human, and their culture was not so very different from that of our own ancestors. In this book, he presents a wider view of the events that led to the migration of the moderns into Europe, what might have happened during the contact of the two populations, and what finally drove the Neanderthals to extinction. It is a view that considers climate, ecology, and migrations of populations, as well as culture and interaction.His conclusion is that the destiny of the Neanderthals and the Moderns was sealed by ecological factors and contingencies. It was a matter of luck that we survived and spread while the Neanderthals dwindled and perished. Had the climate not changed in our favour some 50 million years ago, things would have been very different.There is much current research interest in Neanderthals, much of it driven by attempts to map some of their DNA. But it's not just a question of studying the DNA. The rise and fall of populations is profoundly moulded by the larger scale forces of climate and ecology. And it is only by taking this wider view that we can fully understand the course of events that led to our survival and their demise. The fact that Neanderthals survived until virtually yesterday makes our relationship with them and their tragedy even more poignant. They almost made it, after all.

    But the idea of evolution is far more profound—and far-reaching. Today, a movement of visionary scientists, philosophers, and spiritual thinkers is forging a new understanding of evolution that honors science, reframes culture, and radically updates spirituality. Carter Phipps calls them Evolutionaries. His groundbreaking book provides the first popular guide to these exciting minds who are illuminating the secrets of our past and expanding the vistas of our future.What They're Saying:“Carter Phipps brilliantly expands our understanding of evolution by showing us that a new science is emerging—one that will holistically integrate our understanding of consciousness, cosmology, and evolution.” -Deepak Chopra, Author of How to Know God“This beautifully written book is a splendid survey of evolutionary thought and a significant contribution to the increasingly important conversation between the natural sciences and our spiritual traditions.” -John F. Haught, Senior Fellow at Georgetown’s Woodstock Theological Center“As we search for a new orientation that will serve us for the next millennium, it would be hard to find a better guide than Carter Phipps.” -Brian Swimme Ph.D., California Institute of Integral Studies, author of The Universe Story“A profound and profoundly important new work… absolutely indispensable for lay and professional. The very highest recommendation!” -Ken Wilber, Author of The Integral Vision“Essential reading for anyone who cares about humanity’s future and our role in creating a better one. Evolutionaries, is a brilliant, accessibly written, and eye-opening book.” -Barbara Marx Hubbard, Author of Heal Your Life“A rare book, equally delightful and deep, Phipps explores how our growing knowledge about the evolutionary process catalyzes nothing less than a revolutionary understanding of our selves.” -Elizabeth Debold, Author of Mother Daughter Revolution: From Good Girls to Great Women

    Profiling more than 250 peoples who inhabit the world and examining fascinating facts - from environmental and health issues to beliefs and customs - Human is the definitive illustrated guide to our species.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

      Everything—from biological life to inanimate systems—generates shape and structure and evolves in a sequence of ever-improving designs in order to facilitate flow. River basins, cardiovascular systems, and bolts of lightning are very efficient flow systems to move a current—of water, blood, or electricity. Likewise, the more complex architecture of animals evolve to cover greater distance per unit of useful energy, or increase their flow across the land. Such designs also appear in human organizations, like the hierarchical "flowcharts" or reporting structures in corporations and political bodies. All are governed by the same principle, known as the Constructal Law, and configure and reconfigure themselves over time to flow more efficiently. Written in an easy style that achieves clarity without sacrificing complexity, Design in Nature is a paradigm-shifting book that will fundamentally transform our understanding of the world around us.