Lacking marketed products or substantial profit, the firm nonetheless saw its share price escalate from $35 to $89 in the first few minutes of trading, at that point the largest gain in stock market history. Coming at a time of economic recession and declining technological competitiveness in the United States, the event provoked banner headlines and ignited a period of speculative frenzy over biotechnology as a revolutionary means for creating new and better kinds of pharmaceuticals, untold profit, and a possible solution to national economic malaise. Drawing from an unparalleled collection of interviews with early biotech players, Sally Smith Hughes offers the first book-length history of this pioneering company, depicting Genentech’s improbable creation, precarious youth, and ascent to immense prosperity. Hughes provides intimate portraits of the people significant to Genentech’s science and business, including cofounders Herbert Boyer and Robert Swanson, and in doing so sheds new light on how personality affects the growth of science. By placing Genentech’s founders, followers, opponents, victims, and beneficiaries in context, Hughes also demonstrates how science interacts with commercial and legal interests and university research, and with government regulation, venture capital, and commercial profits. Integrating the scientific, the corporate, the contextual, and the personal, Genentech tells the story of biotechnology as it is not often told, as a risky and improbable entrepreneurial venture that had to overcome a number of powerful forces working against it.

    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

    To meet it, you need a fully integrated text and supplements package that sets the stage for a perfectly choreographed learning experience.

    A unique combination of authoritative content and stimulating applications. * Numerous improvements in the text, based on feedback from the many users of the sixth edition (both instructors and students) * Several thousand end-of-chapter problems have been rewritten to streamline both the presentations and answers * 'Chapter Puzzlers' open each chapter with an intriguing application or question that is explained or answered in the chapter * Problem-solving tactics are provided to help beginning Physics students solve problems and avoid common error * The first section in every chapter introduces the subject of the chapter by asking and answering, "What is Physics?" as the question pertains to the chapter * Numerous supplements available to aid teachers and students The extended edition provides coverage of developments in Physics in the last 100 years, including: Einstein and Relativity, Bohr and others and Quantum Theory, and the more recent theoretical developments like String Theory.

    Fundamentals of Biostatistics with CD-Rom.

    Life remains the only way to make life. Are we still missing a vital ingredient in its creation?      Like Richard Dawkins' The Selfish Gene, which provided a new perspective on how evolution works, Life on the Edge alters our understanding of our world's fundamental dynamics. Bringing together first-hand experience at the cutting edge of science with unparalleled gifts of explanation, Jim Al-Khalili and Johnjoe Macfadden reveal that missing ingredient to be quantum mechanics; the phenomena that lie at the heart of this most mysterious of sciences. Drawing on recent ground-breaking experiments around the world, each chapter in Life on the Edge engages by illustrating one of life's puzzles: How do migrating birds know where to go? How do we really smell the scent of a rose? How do our genes copy themselves with such precision? Life on the Edge accessibly reveals how quantum mechanics can answer these probing questions of the universe. Guiding the reader through the rapidly unfolding discoveries of the last few years, Al-Khalili and McFadden communicate the excitement of the explosive new field of quantum biology and its potentially revolutionary applications, while offering insights into the biggest puzzle of all: what is life? As they brilliantly demonstrate in these groundbreaking pages, life exists on the quantum edge.

    Based on the latest scientific discoveries, Dr Mosley provides a fascinating and detailed understanding of the secrets of this coronavirus, how it spreads, how it infects your body and how your immune system tries to fight back. With access to leading experts, he reports on the battle to find treatments and a safe and effective vaccine (ultimately, the only way to defeat the virus). Armed with the facts about Covid-19 you'll be in a better position to protect yourself and your family as the world begins to reopen. Eating well, sleeping soundly, exercising and managing stress are all vital for keeping your body and immune system in the best possible shape to fight the virus. These are areas where Dr Mosley, creator of the 5:2 diet, is well known for his science-based and practical approach.

    While these are essential, many young ecologists need to figure out how to actually do research themselves. How to Do Ecology provides nuts-and-bolts advice on how to develop a successful thesis and research program. This book presents different approaches to posing testable ecological questions. In particular, it covers the uses, strengths, and limitations of manipulative experiments in ecology. It will help young ecologists consider meaningful treatments, controls, replication, independence, and randomization in experiments, as well as where to do experiments and how to organize a season of work. This book also presents strategies for analyzing natural patterns, the value of alternative hypotheses, and what to do with negative results.Science is only part of being a successful ecologist. This engagingly written book offers students advice on working with other people and navigating their way through the land mines of research. Findings that don't get communicated are of little value. How to Do Ecology suggests effective ways to communicate information in the form of journal articles, oral presentations, and posters. Finally, it outlines strategies for developing successful grant and research proposals. Numerous checklists, figures, and boxes throughout the book summarize and reinforce the main points. In short, this book makes explicit many of the unspoken assumptions behind doing good research in ecology, and provides an invaluable resource for meaningful conversations among ecologists.

    Weschler thoroughly explains the empowering Fertility Awareness Method, which in only a couple minutes a day allows a woman to:-Enjoy highly effective, scientifically proven birth control without chemicals or devices-Maximize her chances of conception or expedite fertility treatment by identifying impediments to conception-Increase the likelihood of choosing the gender of her baby-Gain control of her sexual and gynecological health

    Scott guides readers through the latest advances in stem cell research in clear, accessible language, telling the stories of the researchers who are exploring the potential of stem cells to cure cancer, grow new organs, and repair the immune system. He also leads readers through a discussion of the question at the heart of the explosive ethical debate: How, as a society, do we balance our responsibilities to the unborn and the sick? Stem Cell Now is essential reading for anyone who wants to build an informed opinion on stem cell research.

    With this book, you'll learn how to load data, assemble and disassemble data objects, navigate R's environment system, write your own functions, and use all of R's programming tools.RStudio Master Instructor Garrett Grolemund not only teaches you how to program, but also shows you how to get more from R than just visualizing and modeling data. You'll gain valuable programming skills and support your work as a data scientist at the same time.Work hands-on with three practical data analysis projects based on casino gamesStore, retrieve, and change data values in your computer's memoryWrite programs and simulations that outperform those written by typical R usersUse R programming tools such as if else statements, for loops, and S3 classesLearn how to write lightning-fast vectorized R codeTake advantage of R's package system and debugging toolsPractice and apply R programming concepts as you learn them

    The scientific data on the link between lifestyle, environmental factors, and cancer risk has been accumulating at an accelerated rate over the past decade: Every week we learn something more that we can do as individuals to decrease the risk of can-cer and improve the likelihood of long-term survival. Many of us--patients and doctors included--do not realize that changes in our daily choices and habits can improve quality of life, increase the chances of survival, and aid in the healing process for those with a diagnosis. These ideas were pioneered in David Servan-Schreiber's Anticancer: A New Way of Life, and became the basis for a research study developed by Lorenzo Cohen and Servan-Schreiber at The University of Texas MD Anderson Cancer Center.Introducing the concept of the "Mix of Six," Cohen and Alison Jefferies make an informed case that building social and emotional support; manag-ing stress; improving sleep, exercise, and diet; and minimizing exposure to environmental toxins work together to promote an optimal environment for health and well-being. While each plays an inde-pendent role, the synergy created by all six factors can radically transform health; delay or prevent many cancers; support conventional treatments; and significantly improve quality of life--as many testi-monies and stories of those in the anticancer com-munity eloquently show.Anticancer Living provides an accessible, pre-scriptive guide to wellness based on the latest scien-tific findings and clinical trials, and it showcases the community of doctors, researchers, caregivers, and patients who have been inspired to create change.*Includes a Bonus PDF with charts, graphs, chapter summaries, and appendices.

    Numerous tables and figures.

    Judy Mikovits and Kent Heckenlively, this book reviews the evidence for and against widespread public masking as provided by the Centers for Disease Control and the Mayo Clinic, as well as top scientific publications such as the New England Journal of Medicine and The Lancet. This debate needs to take place without fear and paranoia. Important questions raised in this book are the affect of masks on oxygen and carbon dioxide levels, how SARS-CoV-2 spreads, the effectiveness of various types of masks, those who are most vulnerable to COVID-19, and whether our children should go back to school in the fall, and if so, what measures they should take.The authors' previous book, PLAGUE OF CORRUPTION, was the runaway science bestseller of 2020, and the authors bring that same passion and attention to detail to the mask question. As politicians and bureaucrats of all stripes are weighing in on this question, with some placing their cities and states under mandatory masking provisions, we need to understand the science behind their decisions. Are such measures a reasonable response to current circumstances, or is it a dramatic overreach, which in many cases might make the situation even worse? America desperately needs this public conversation to take place with the best science we have available. As Americans have always done during difficult times, we must summon the courage to have these challenging conversations.

    And as outbreaks of COVID-19, Ebola, MERS, and Zika have demonstrated, we are woefully underprepared to deal with the fallout. So what can -- and must -- we do in order to protect ourselves from mankind's deadliest enemy?Drawing on the latest medical science, case studies, policy research, and hard-earned epidemiological lessons, Deadliest Enemy explores the resources and programs we need to develop if we are to keep ourselves safe from infectious disease. The authors show how we could wake up to a reality in which many antibiotics no longer cure, bioterror is a certainty, and the threat of a disastrous influenza or coronavirus pandemic looms ever larger. Only by understanding the challenges we face can we prevent the unthinkable from becoming the inevitable.Deadliest Enemy is high scientific drama, a chronicle of medical mystery and discovery, a reality check, and a practical plan of action.