Rough receives the test results that confirm she is a carrier of the genetic condition "hypohidrotic ectodermal dysplasia," or H.E.D., it propels her on a journey deep into her family's past in the American West.At first glance, H.E.D. seems only to be a superficial condition: a peculiar facial bone structure, sparse hair, few teeth, and an inability to sweat. But a closer look reveals the source of a lifetime of infections, breathing problems, and drug dependency for Bonnie's grandfather Earl, who suffered from the disorder. After a boyhood as a small-town oddity and an adulthood fraught with disaster, Earl died penniless and alone at the age of 49. Bonnie's mother was left with an inheritance that included not just the gene for H.E.D., but also the emotional pain that came from witnessing her father's misery.As Bonnie and her husband consider becoming parents themselves, their biological legacy haunts every decision. The availability of genetic testing gives them new choices to make, choices more excruciating than any previous generation could have imagined. Ultimately, Carrier is a story of a modern moral crisis, one that reveals the eternal tension between past and future."

    In riveting first-person prose, Dr. Brendan Reilly takes us to the front lines of medicine today. Whipsawed by daily crises and frustrations, Reilly must deal with several daunting challenges simultaneously: the extraordinary patients under his care on the teeming wards of a renowned teaching hospital; the life-threatening illnesses of both of his ninety-year-old parents; and the tragic memory of a cold case from long ago that haunts him still. As Reilly’s patients and their families survive close calls, struggle with heartrending decisions, and confront the limits of medicine’s power to cure, One Doctor lays bare a fragmented, depersonalized, business-driven health-care system where real caring is hard to find. Every day, Reilly sees patients who fall through the cracks and suffer harm because they lack one doctor who knows them well and relentlessly advocates for their best interests.Filled with fascinating characters in New York City and rural New England — people with dark secrets, mysterious illnesses, impossible dreams, and many kinds of courage — One Doctor tells their stories with sensitivity and empathy, reminding us of professional values once held dear by all physicians. But medicine has changed enormously during Reilly’s career, for both better and worse, and One Doctor is a cautionary tale about those changes. It is also a hopeful, inspiring account of medicine’s potential to improve people’s lives, Reilly’s quest to understand the "truth" about doctoring, and a moving testament to the difference one doctor can make.

    We see it, touch it, and live in it every day. It is a habitat for a mesmerizingly complex world of micro-organisms and physical functions that are vital to our health and our survival. It is also a waste removal plant, a warning system for underlying disease and a dynamic immune barrier to infection. One of the first things people see about us, skin is crucial to our sense of identity, providing us with social significance and psychological meaning. And yet our skin and the fascinating way it functions is largely unknown to us. In prose as lucid as his research underlying it is rigorous, blending in memorable stories from the past and from his own medical experience, Monty Lyman has written a revelatory book exploring our outer surface that will surprise and enlighten in equal measure. Through the lenses of science, sociology, and history--on topics as diverse as the mechanics and magic of touch (how much goes on in the simple act of taking keys out of a pocket and unlocking a door is astounding), the close connection between the skin and the gut, what happens instantly when one gets a paper cut, and how a midnight snack can lead to sunburn--Lyman leads us on a journey across our most underrated and unexplored organ and reveals how our skin is far stranger, more wondrous, and more complex than we have ever imagined.

    But they don’t always know how to care for them.Hardly anyone is happy with American healthcare these days. Patients are getting sicker and going bankrupt from medical bills. Doctors are burning out and making dangerous mistakes. Both parties blame our nation’s outdated and dysfunctional healthcare system. But that’s only part of the problem.In this important and timely book, Dr. Robert Pearl shines a light on the unseen and often toxic culture of medicine. Today’s physicians have a surprising disdain for technology, an unhealthy obsession with status, and an increasingly complicated relationship with their patients. All of this can be traced back to their earliest experiences in medical school, where doctors inherit a set of norms, beliefs, and expectations that shape almost every decision they make, with profound consequences for the rest of us.Uncaring draws an original and revealing portrait of what it’s actually like to be a doctor. It illuminates the complex and intimidating world of medicine for readers, and in the end offers a clear plan to save American healthcare.

    They even influence whether we develop symptoms at all. Written with brutal honesty, deep compassion, and a wry sense of humour, Head First examines difficult cases that illuminate some of our most puzzling and controversial medical issues-from the tragedy of suicide, to the stigma surrounding obesity, to the ongoing misery of chronic fatigue. Ultimately he finds that our medical model has failed us by promoting specialization and overlooking perhaps the single most important component of our health: our state of mind.

    Packed with research-based strategies and practical tools, this fully customizable book will show anyone who suffers with insomnia how to get a good night’s sleep—night after night—for a better life.Everyone struggles with sleep from time to time, but when sleepless nights and overtired days become the norm, your well-being is compromised, and frustration and worry increase—including concerns about what’s stopping you from getting the sleep you need, and what can be done about it. So, how do you stop the cycle of relentless worries and restless nights?End the Insomnia Struggle offers a comprehensive, medication-free program that can be individually tailored for anyone who struggles with insomnia. Integrating the physiology of sleep, and proven-effective approaches from cognitive behavioral therapy for insomnia (CBT-I) and acceptance and commitment therapy (ACT), this book provides step-by-step guidance for developing your own treatment plan according to your particular challenges with insomnia.With this book, you’ll have everything you need to overcome the relentless thoughts, ruminations, and stress of insomnia. Utilizing these evidence-based strategies and easy-to-use tools, you’ll finally get to sleep, stay asleep, and wake up rested and ready to face the world as your best self, day after day.

    In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but world-wide, the pandemic gained the notorious title of “Spanish Flu." Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war), while European deaths totaled more than two million.Amid the war, some governments suppressed news of the outbreak. Even as entire battalions were decimated, with both the Allies and the Germans suffering massive casualties, the details of many servicemen’s deaths were hidden to protect public morale. Meanwhile, civilian families were being struck down in their homes. Philadelphia ran out of gravediggers and coffins, and mass burial trenches had to be excavated with steam shovels. Spanish flu conjured up the specter of the Black Death of 1348 and the great plague of 1665, while the medical profession, shattered after five terrible years of conflict, lacked the resources to contain and defeat this new enemy. Through primary and archival sources, historian Catharine Arnold gives readers the first truly global account of this terrible epidemic.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    Perry Baird was a rising medical star in the late 1920s and 1930s. Early in his career, ahead of his time, he grew fascinated with identifying the biochemical root of manic depression, just as he began to suffer from it himself. By the time the results of his groundbreaking experiments were published, Dr. Baird had been institutionalized multiple times, his medical license revoked, and his wife and daughters estranged. He later received a lobotomy and died from a consequent seizure, his research incomplete, his achievements unrecognized.Mimi Baird grew up never fully knowing this story, as her family went silent about the father who had been absent for most of her childhood. Decades later, a string of extraordinary coincidences led to the recovery of a manuscript which Dr. Baird had worked on throughout his brutal institutionalization, confinement, and escape. This remarkable document, reflecting periods of both manic exhilaration and clear-headed health, presents a startling portrait of a man who was a uniquely astute observer of his own condition, struggling with a disease for which there was no cure, racing against time to unlock the key to treatment before his illness became impossible to manage.Fifty years after being told her father would forever be “ill” and “away,” Mimi Baird set off on a quest to piece together the memoir and the man. In time her fingers became stained with the lead of the pencil he had used to write his manuscript, as she devoted herself to understanding who he was, why he disappeared, and what legacy she had inherited. The result of his extraordinary record and her journey to bring his name to light is He Wanted the Moon, an unforgettable testament to the reaches of the mind and the redeeming power of a determined heart.Soon to be a major motion picture, from Brad Pitt and Tony Kushner

    This moving and inspiring book tells the tale of a man pulled from the brink of death by music who, in turn, uses music as medicine to help heal others. Andrew Schulman, a fifty-seven-year-old professional guitarist, had a close brush with death on the night of July 16, 2009. Against the odds—with the help of music—he survived: A medical miracle.Once fully recovered, Andrew resolved to dedicate his life to bringing music to critically ill patients at Mount Sinai Beth Israel’s ICU. In Waking the Spirit, you’ll learn the astonishing stories of the people he’s met along the way—both patients and doctors—and see the incredible role music can play in a modern hospital setting.In his new work as a medical musician, Andrew has met with experts in music, neuroscience, and medicine. In this book, he shares with readers an overview of the cutting-edge science and medical theories that illuminate this exciting field.This book explores the power of music to heal the body and awaken the spirit.

    This could be as close to a fountain of youth as mankind will ever come, the truly scientific answer to how to reverse or prevent the debilitating effects of aging, including memory loss, weight gain, sexual dysfunction, and Alzheimers.Dr. Eric Braverman, a leading figure in the practice of brain-body health care, reveals the dramatic impact that proper brain nourishment can have on the quality of our lives. His key to longevity and well-being is balancing the brains four important neurotransmitters. A simple test determines which of the four is dominant in you, and what you can do to maintain the right balance, by modifying your diet with both foods and natural supplements. Proven effective for thousands of patients in Dr. Bravermans practice, this groundbreaking approach will help anyone make the most of his or her life, free of the major illnesses (such as cancer and heart disease) and minor ailments as well.

    This accessible and easy-to-follow guide examines the health risks posed by typical Western eating habits and explains how a diet rich in vegetables, fruits, whole grains, legumes, mushrooms, nuts, seeds, herbs and spices can lead to lower blood pressure, healthy weight management, and longer life.Their flexible, customizable approach to eating challenges the conventional idea of breakfast, lunch, and dinner and focuses instead on soups, salads, sides, and sweets. With 100 delicious recipes to choose from, The Healthspan Solution make adopting a plant-based lifestyle simple and sustainable.- Evidence-based research on the scientific underpinnings of the healthspan diet - Easy-to-follow guidelines simplify food choices without being restrictive - Beautifully photographed recipes offer options and flexibility Praise for The Healthspan Solution "Ray and Julieanna didn't write a fad diet book. It's about making a permanent lifestyle transformation. The magic is I still can eat anything I want. The trick is what I want has profoundly changed. They did the trick for me and saved my life--now let them help you."--Penn Jillette, Las Vegas entertainer and magician"Ray is a scientific visionary and Julieanna is a master of nutrition. Together they've written a fact-based recipe book for longevity that belongs in every kitchen. Buy it."--David Sinclair, PhD, AO, Professor of Genetics, Harvard Medical School"Working with Julieanna and Ray has given me a profoundly new understanding of how food impacts health and how what we eat is often dictated by social influences. I'm excited to be a part of their effort to push to this message out to a far bigger audience."--Cyan Banister, angel investor and entrepreneur"Julieanna and Ray are an incredible team. While others have sought to demonstrate the adequacy of an exclusively plant-sourced diet, they teach how it can be superior and mimics longevity research."--Rich Roll, plant-powered ultra athlete and author

    But how did Watson and Crick do it—and why were they the ones who succeeded?In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel.The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised.A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.

    You’ll be there as Dr. Kristine Guleserian, noted pediatric cardiothoracic surgeon, fixes the tiny hearts of the tiniest children. Follow the young boy who gets a new heart and then, three weeks later, joins Dr. Guleserian on the mound at Fenway Park to throw out the first pitch at a World Series game. Discover the years of training Dr. G went through to become the highly respected surgeon she is today. See how her warmth, humor, intelligence and dedication provide a shining example of what is good about the American health care system. To get a closer look than this, you’d have to scrub in.

    According to Dr. Rashid Buttar, author of The 9 Steps to Keep the Doctor Away, "Ty Bollinger's book, Cancer-Step Outside the Box, is an extraordinarily thorough and courageously well written book, brought to fruition by the dedication of a son for his departed parents. I found it difficult to put down this exceptional book once I began reading it and plan on recommending it to all my patients suffering from cancer who seek treatment at our clinic so that the light of truth and hope contained within this book can shine brightly on them as well." In the words of cancer survivor, Brad Matznick, I am not a journalist, that 's Ty 's job, so I won t drag this out ... I am a cancer survivor and this book was a huge contribution to my survival (it 's one of the best books on the subject). Ty is a rebel... maybe even somewhat eccentric, but you can t ignore what he 's saying. Read this book if you or someone you care about has cancer ... nuff said. With satisfied readers in over 50 countries world wide, Cancer - Step Outside the Box is a roadmap to successfully treating cancer and regaining your health This book is chock full of the most effective, non-toxic cancer treatments in the world. Truth be told, there are many potent and well-proven alternative strategies for preventing and treating cancer... without surgery, chemotherapy, or radiation (the Big 3 ). Inside this book, you will find a wealth of information that your doctor probably doesn't know. Here's why: while at medical school, doctors learn a very drug-intensive style of medicine, because multinational pharmaceutical companies ( Big Pharma ) funds the medical schools. As a result, most doctors are still thinking inside the box when it comes to cancer treatments. The cancer box is largely the creation of Big Pharma attempting to peddle their poisons (such as chemotherapy) in an effort to increase shareholder profits. Sadly, these profits are generated at the expense of cancer patients. In the words of radio talk show icon, Jeff Rense, I have been involved with so called 'alternative approaches to cancer' for a long time. This book is 'the Bible' - buy it and you will be amazed. It is a masterpiece." This book succinctly explains the facts and deceptions about cancer and cancer treatments, it documents multiple cases of persecution and suppression of effective natural cancer treatments, it details the most potent advanced cancer treatment protocols, and it clearly explains the relationship between nutrition and cancer. The author is not a medical doctor. He is a researcher who has compiled the most concise, easily readable, comprehensive book on alternative cancer treatments and health. This book is a gold mine of information, helpful to cancer patients, those attempting to prevent cancer, and health care practitioners alike. According to Dr. Pavel Yakovlev (Oncosurgeon in the Ukraine), the material in your book is enriching and hope-giving for clinical practice I made many notes while reading it to be applied to my work. Elaine Hulliberger, breast cancer survivor, states: I had terminal cancer and used Ty Bollinger's information on non-toxic supplements and the nutritional information along with traditional medicine. Anyone who has cancer, or knows someone with cancer should get this book and read it from cover to cover. I'm alive today because I did.