He Jiankui announced that he had created the first genetically modified babies—twin girls named Lulu and Nana—sending shockwaves around the world. A year later, a Chinese court sentenced Dr. He to three years in prison for "illegal medical practice."As scientists elsewhere start to catch up with China’s vast genetic research program, gene editing is fueling an innovation economy that threatens to widen racial and economic inequality. Fundamental questions about science, health, and social justice are at stake: Who gets access to gene editing technologies? As countries loosen regulations around the globe, from the U.S. to Indonesia, can we shape research agendas to promote an ethical and fair society?Eben Kirksey takes us on a groundbreaking journey to meet the key scientists, lobbyists, and entrepreneurs who are bringing cutting-edge genetic engineering tools like CRISPR to your local clinic. He also ventures beyond the scientific echo chamber, talking to disabled scholars, doctors, hackers, chronically-ill patients, and activists who have alternative visions of a genetically modified future for humanity.The Mutant Project empowers us to ask the right questions, uncover the truth, and navigate this brave new world.

    But is old age all doom and gloom?Not at all! While it's true that some functions in the aging brain decline, neuroscientists have discovered that many other brain functions remain stable - or even improve - as we age. Furthermore, nurture plays as significant a role as nature, and there are a number of strategies you can implement to stave off declining brain function, including:Incorporating physical activity into your routineEating a healthy dietMaintaining a vibrant social lifeReducing your stressThe science behind the aging brain tells a fascinating - and often counterintuitive - story. Is "aging" a disease or merely a natural occurrence that produces disease-like symptoms? If humans are biologically programmed to survive and thrive, why do we age at all? Is it possible (or even desirable) to "cure" aging altogether?Delve into these questions and more in The Aging Brain. Taught by a neuroscientist and award-winning professor at the University of Michigan, these 12 eye-opening lectures will give you a wealth of new insights into what happens to the brain over time - as well as strategies to mitigate the effects of aging and enhance your quality of life into old age.With a mix of scientific research and practical applications, Professor Polk brings cutting-edge science to life. He takes you down to the cellular and even molecular levels of the brain to show you why certain functions decline, how some aspects of brain aging are under genetic control, and what you can do to prolong your health and keep your mind sharp. Aging affects us all, but you have some control over how it affects you.

    The Power of Rest provides a low-cost, low-risk answer to some pressing health concerns, and is an important adjunct for those already investing time, energy, and money in their health. Readers interested in a new plan to help with sleep disruptions, fatigue, lack of zest, weight loss, or diabetes will find many helpful suggestions in The Power of Rest.

    How do biology, upbringing, and outside influences intersect to produce altruistic and heroic behavior? And how can we encourage this behavior in corporations, classrooms, and individuals? Using dozens of fascinating real-life examples, Elizabeth Svoboda explains how our genes compel us to do good for others, how going through suffering is linked to altruism, and how acting heroic can greatly improve your mental health. She also reveals the concrete things we can do to encourage our most heroic selves to step forward. It’s a common misconception that heroes are heroic just because they’re innately predisposed to be that way. Svoboda shows why it’s not simply a matter of biological hardwiring and how anyone can be a hero if they're committed to developing their heroic potential.

    A riveting account of three heroic astronauts who took one of the most dangerous space flights ever, from the New York Times bestselling author of Shadow Divers. In early 1968, the Apollo program was on shaky footing. President Kennedy's end-of-decade deadline to put a man on the Moon was in jeopardy, and the Soviets were threatening to pull ahead in the space race. By August 1968, with its back against the wall, NASA decided to scrap its usual methodical approach and shoot for the heavens. With just four months to prepare--a fraction of the normal time--the agency would send the first men in history to the Moon. In a year of historic violence and discord--the Tet offensive, the assassinations of MLK and RFK, the Chicago DNC riots--the Apollo 8 mission was the boldest test of what America could do. With a focus on astronauts Frank Borman, Jim Lovell, and Bill Anders, and their wives and children, this is a vivid, gripping, you-are-there narrative that shows anew the epic danger involved, and the singular bravery it took, for man to leave Earth for the first time--and to arrive at a new world.

    I'm going to do this in a similar way I've done it for sex and relationships in my work over the last couple decades for young people and adults alike: by talking out loud, shamelessly and frankly, about what others are afraid or ashamed to, much in the way your favorite loudmouth aunt might have if she made this kind of stuff her life's work and if your family also didn't always apparently forget to invite her to everything."Corinna has been on the cutting edge of health for more than twenty years, always talking about what people are most afraid, ashamed, or embarrassed of. What Fresh Hell Is This? is no different. It's a companion for everyone who's reached this "what to expect when you're not expected to expect anything" time of life. It's a health-forward, feminist, no b.s. (and damn funny) perimenopause guide for the generation that time forgot (aka GenXers), offering straightforward descriptions of our bodies, minds, lives and what's going on with them during this time of hormonal chaos. Heather Corinna tells you what to expect and what to do, all while busting some myths and offering real self-care tips so you can get through this. With practical, clear information that also includes affected populations who have long been left out of the discussion, like those with disabilities, queer, transgender, nonbinary and other gender-diverse people, the working class and other marginalized folks, What Fresh Hell Is This? an accessible and inclusive guide for anyone who is experiencing the hot fire of perimenopause.

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    Drawing on newly available papers of Jonas Salk, Albert Sabin and other key players, Oshinsky paints a suspenseful portrait of the race for the cure, weaving a dramatic tale centered on the furious rivalry between Salk and Sabin. He also tells the story of Isabel Morgan, perhaps the most talented of all polio researchers, who might have beaten Salk to the prize if she had not retired to raise a family.Oshinsky offers an insightful look at the National Foundation for Infantile Paralysis, which was founded in the 1930s by FDR and Basil O'Connor, it revolutionized fundraising and the perception of disease in America. Oshinsky also shows how the polio experience revolutionized the way in which the government licensed and tested new drugs before allowing them on the market, and the way in which the legal system dealt with manufacturers' liability for unsafe products. Finally, and perhaps most tellingly, Oshinsky reveals that polio was never the raging epidemic portrayed by the media, but in truth a relatively uncommon disease. But in baby-booming America--increasingly suburban, family-oriented, and hygiene-obsessed--the specter of polio, like the specter of the atomic bomb, soon became a cloud of terror over daily life.Both a gripping scientific suspense story and a provocative social and cultural history, Polio opens a fresh window onto postwar America.

    Although, prior to the war, female doctors were restricted to treating women and children, Flora and Louisa's work was so successful that the British Army asked them to set up a hospital in the heart of London. Nicknamed the Suffragettes' Hospital, Endell Street soon became known for its lifesaving treatments and lively atmosphere.In No Man's Land, Wendy Moore illuminates this turbulent moment when women were, for the first time, allowed to operate on men. Their fortitude and brilliance serve as powerful reminders of what women can achieve against all odds.

    Though within the scientific community a certain stigma is attached to chance discovery because it is wrongly seen as pure luck, happy accidents happen every day and Meyers shows how it takes intelligence, insight, and creativity to recognize a "Eureka! I found what I wasn't look for!" moment and know what to do next. Penicillin, chemotherapy drugs, X-rays, Valium, the Pap smear, and Viagra were all discovered accidentally, stumbled upon in search of something else. In discussing these medical breakthroughs and others, Dr. Meyers makes a cogent, highly engaging argument for a more creative, rather than purely linear, approach to science.

    Using meticulous multidisciplinary science, as well as reviewing the history of our understanding about evolution, this book makes the case that aging is not something that “just happens,” nor is it the result of wear and tear or a genetic inevitability. Rather, aging has a fascinating evolutionary purpose: to stabilize populations and ecosystems, which are ever-threatened by cyclic swings that can lead to extinction.When a population grows too fast it can put itself at risk of a wholesale wipeout. Aging has evolved to help us adjust our growth in a sustainable fashion as well as prevent an ecological crisis from starvation, predation, pollution, or infection.This dynamic new understanding of aging is provocative, entertaining, and pioneering, and will challenge the way we understand aging, death, and just what makes us human.

    But why are they on the rise?     Science writer Moises Velasquez-Manoff offers a new and controversial way of thinking about autoimmune disease—one that may foster a paradigm shift in the way we think about health and hygiene.     In the early twentieth century, the dawn of improved hygiene, water treatment, vaccines, and antibiotics saved countless lives, eradicating diseases that had plagued humanity for millennia. But in the wake of this triumph, a new threat arose: The human immune system began to malfunction.     A growing body of evidence suggests that the very steps we took to cure these maladies have also eradicated organisms that once kept our bodies in balance. To combat this “epidemic of absence,” a group of scientists has begun deliberately reintroducing parasitic worms—helminthes—to calm the immune system of their hosts. This book takes a close look at the scientists at the vanguard of “worm therapy,” which has been proven to not only preempt immune malfunction, but to send a number of disorders—from Crohn’s Disease to multiple sclerosis to asthma—into remission.     Exploring the greater context of rampant immune system dysfunction in the developed world, and its implications for developing countries, Velasquez-Manoff offers an eye-opening and elegant portrait of science’s new view of the human organism.

     The tales are far too common to be complete fabrications, yet too anecdotal and outside the medical mainstream to be taken seriously scientifically. How do we explain them and the growing popularity of alternative medicine more generally? Is there a biological basis for practices like acupuncture, tai chi, chiropractic, and energy healing? Who are the faithful patients and practitioners who tell these stories and speak of such mystical-seeming concepts as qi, chakras, and meridians in the first place? In The Magic Feather Effect, author and journalist Melanie Warner attempts to answer these questions, taking us on a vivid, fascinating journey through the world of alternative medicine. Crossing continents and sides of the debate, visiting prestigious research clinics and ordinary people’s homes, she investigates the scientific underpinning for the purportedly magical results of these practices and reveals not only the medical power of beliefs and placebo effects, but also the range, limits, and uses of the surprising system of self-healing that resides inside us. Equal parts helpful, illuminating, and compelling, The Magic Feather Effect is a brilliant exploration of some of the world’s most popular health treatments, the people who seek them, the scientists who study them, and the reasons they may work.

    Sooner or later each of us is obliged, at least for a spell, to identify ourselves as citizens of that other place." Now more than 133 million Americans live with chronic illness, accounting for nearly three-quarters of all health care dollars, and untold pain and disability.There has been an alarming rise in illnesses that defy diagnosis through clinical tests or have no known cure. Millions of people, especially women, with illnesses such as irritable bowel syndrome, chronic pain, and chronic fatigue syndrome face skepticism from physicians and the public alike. And people with diseases as varied as cardiovascular disease, HIV, certain cancers, and type 2 diabetes have been accused of causing their preventable illnesses through their lifestyle choices.We must balance our faith in medical technology with awareness of the limits of science, and confront our throwback beliefs that people who are sick have weaker character than those who are well. Through research and patient narratives, health writer Laurie Edwards explores patient rights, the role of social media in medical advocacy, the origins of our attitudes about chronic illness, and much more. What The Noonday Demon did for people suffering from depression, In the Kingdom of the Sick does for those who are chronically ill.