It discusses new results, along with applications of probability theory to a variety of problems. The book contains many exercises and is suitable for use as a textbook on graduate-level courses involving data analysis. Aimed at readers already familiar with applied mathematics at an advanced undergraduate level or higher, it is of interest to scientists concerned with inference from incomplete information.

    It shows how causality has grown from a nebulous concept into a mathematical theory with significant applications in the fields of statistics, artificial intelligence, philosophy, cognitive science, and the health and social sciences. Pearl presents a unified account of the probabilistic, manipulative, counterfactual and structural approaches to causation, and devises simple mathematical tools for analyzing the relationships between causal connections, statistical associations, actions and observations. The book will open the way for including causal analysis in the standard curriculum of statistics, artifical intelligence, business, epidemiology, social science and economics. Students in these areas will find natural models, simple identification procedures, and precise mathematical definitions of causal concepts that traditional texts have tended to evade or make unduly complicated. This book will be of interest to professionals and students in a wide variety of fields. Anyone who wishes to elucidate meaningful relationships from data, predict effects of actions and policies, assess explanations of reported events, or form theories of causal understanding and causal speech will find this book stimulating and invaluable. Professor of Computer Science at the UCLA, Judea Pearl is the winner of the 2008 Benjamin Franklin Award in Computers and Cognitive Science.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    Cells are built out of molecular circuits that perform logical operations, as electronic devices do, but with unique properties. Bray argues that the computational juice of cells provides the basis of all the distinctive properties of living systems: it allows organisms to embody in their internal structure an image of the world, and this accounts for their adaptability, responsiveness, and intelligence.In Wetware, Bray offers imaginative, wide-ranging and perceptive critiques of robotics and complexity theory, as well as many entertaining and telling anecdotes. For the general reader, the practicing scientist, and all others with an interest in the nature of life, the book is an exciting portal to some of biology’s latest discoveries and ideas.

    … The book the National Security Agency wanted never to be published." –Wired Magazine "…monumental… fascinating… comprehensive… the definitive work on cryptography for computer programmers…" –Dr. Dobb's Journal"…easily ranks as one of the most authoritative in its field." —PC Magazine"…the bible of code hackers." –The Millennium Whole Earth CatalogThis new edition of the cryptography classic provides you with a comprehensive survey of modern cryptography. The book details how programmers and electronic communications professionals can use cryptography—the technique of enciphering and deciphering messages-to maintain the privacy of computer data. It describes dozens of cryptography algorithms, gives practical advice on how to implement them into cryptographic software, and shows how they can be used to solve security problems. Covering the latest developments in practical cryptographic techniques, this new edition shows programmers who design computer applications, networks, and storage systems how they can build security into their software and systems. What's new in the Second Edition? * New information on the Clipper Chip, including ways to defeat the key escrow mechanism * New encryption algorithms, including algorithms from the former Soviet Union and South Africa, and the RC4 stream cipher * The latest protocols for digital signatures, authentication, secure elections, digital cash, and more * More detailed information on key management and cryptographic implementations

    if you want to understand how the concept of life is changing, read this' Professor Andrew Briggs, University of OxfordWhen Darwin set out to explain the origin of species, he made no attempt to answer the deeper question: what is life? For generations, scientists have struggled to make sense of this fundamental question. Life really does look like magic: even a humble bacterium accomplishes things so dazzling that no human engineer can match it. And yet, huge advances in molecular biology over the past few decades have served only to deepen the mystery. So can life be explained by known physics and chemistry, or do we need something fundamentally new?In this penetrating and wide-ranging new analysis, world-renowned physicist and science communicator Paul Davies searches for answers in a field so new and fast-moving that it lacks a name, a domain where computing, chemistry, quantum physics and nanotechnology intersect. At the heart of these diverse fields, Davies explains, is the concept of information: a quantity with the power to unify biology with physics, transform technology and medicine, and even to illuminate the age-old question of whether we are alone in the universe.From life's murky origins to the microscopic engines that run the cells of our bodies, The Demon in the Machine is a breath-taking journey across the landscape of physics, biology, logic and computing. Weaving together cancer and consciousness, two-headed worms and bird navigation, Davies reveals how biological organisms garner and process information to conjure order out of chaos, opening a window on the secret of life itself.

    It discusses neuroanatomy, cell and molecular mechanisms and signaling through a cognitive approach to behaviour. It features an expanded treatment of the nervous system, neurological and psychiatric diseases and perception.

    Difficult issues need to be figured out, such as scalability, consistency, reliability, efficiency, and maintainability. In addition, we have an overwhelming variety of tools, including relational databases, NoSQL datastores, stream or batch processors, and message brokers. What are the right choices for your application? How do you make sense of all these buzzwords?In this practical and comprehensive guide, author Martin Kleppmann helps you navigate this diverse landscape by examining the pros and cons of various technologies for processing and storing data. Software keeps changing, but the fundamental principles remain the same. With this book, software engineers and architects will learn how to apply those ideas in practice, and how to make full use of data in modern applications. Peer under the hood of the systems you already use, and learn how to use and operate them more effectively Make informed decisions by identifying the strengths and weaknesses of different tools Navigate the trade-offs around consistency, scalability, fault tolerance, and complexity Understand the distributed systems research upon which modern databases are built Peek behind the scenes of major online services, and learn from their architectures

    Requiring essentially no background apart from mathematical maturity, the book can be used as a reference for self-study for anyone interested in complexity, including physicists, mathematicians, and other scientists, as well as a textbook for a variety of courses and seminars. More than 300 exercises are included with a selected hint set.

    This book is an insider's guide to these little understood topics.Author Jeremy Zawodny has managed large numbers of MySQL servers for mission-critical work at Yahoo!, maintained years of contacts with the MySQL AB team, and presents regularly at conferences. Jeremy and Derek have spent months experimenting, interviewing major users of MySQL, talking to MySQL AB, benchmarking, and writing some of their own tools in order to produce the information in this book.In "High Performance MySQL" you will learn about MySQL indexing and optimization in depth so you can make better use of these key features. You will learn practical replication, backup, and load-balancing strategies with information that goes beyond available tools to discuss their effects in real-life environments. And you'll learn the supporting techniques you need to carry out these tasks, including advanced configuration, benchmarking, and investigating logs.Topics include: A review of configuration and setup optionsStorage engines and table typesBenchmarkingIndexesQuery OptimizationApplication DesignServer PerformanceReplicationLoad-balancingBackup and RecoverySecurity

    Each chapter is relatively self-contained and can be used as a unit of study. The algorithms are described in English and in a pseudocode designed to be readable by anyone who has done a little programming. The explanations have been kept elementary without sacrificing depth of coverage or mathematical rigor.

    However, according to Hofstadter, the formal system that underlies all mental activity transcends the system that supports it. If life can grow out of the formal chemical substrate of the cell, if consciousness can emerge out of a formal system of firing neurons, then so too will computers attain human intelligence. Gödel, Escher, Bach is a wonderful exploration of fascinating ideas at the heart of cognitive science: meaning, reduction, recursion, and much more.

    You'll also learn how to make your programs interactive and how to test your code safely before adding it to a project. In the second half of the book, you'll put your new knowledge into practice with three substantial projects: a Space Invaders-inspired arcade game, data visualizations with Python's super-handy libraries, and a simple web app you can deploy online.As you work through Python Crash Course, you'll learn how to: Use powerful Python libraries and tools, including matplotlib, NumPy, and PygalMake 2D games that respond to keypresses and mouse clicks, and that grow more difficult as the game progressesWork with data to generate interactive visualizationsCreate and customize simple web apps and deploy them safely onlineDeal with mistakes and errors so you can solve your own programming problemsIf you've been thinking seriously about digging into programming, Python Crash Course will get you up to speed and have you writing real programs fast. Why wait any longer? Start your engines and code!

    In doing so, the authors synthesize information from astronomy, biology, and paleontology, and apply it to what we know about the rise of life on Earth and to what could possibly happen elsewhere in the universe. Everyone who has been thrilled by the recent discoveries of extrasolar planets and the indications of life on Mars and the Jovian moon Europa will be fascinated by Rare Earth, and its implications for those who look to the heavens for companionship.

    Time-saving study tools help readers arrive at a complete understanding of human anatomy. KEY TOPICS: An Introduction to Anatomy, The Cell, Tissues and Early Embryology, The Integumentary System, The Skeletal System: Osseous Tissue and Skeletal Structure, The Skeletal System: Axial Division, The Skeletal System: Appendicular Division, The Skeletal System: Articulations, The Muscular System: Skeletal Muscle Tissue and Muscle Organization, The Muscular System: Axial Musculature, The Muscular System: Appendicular Musculature, Surface Anatomy and Cross-Sectional Anatomy, The Nervous System: Neural Tissue, The Nervous System: The Spinal Cord and Spinal Nerves, The Nervous System: The Brain and Cranial Nerves, The Nervous System: Pathways And Higher-Order Functions, The Nervous System:  Autonomic Division, The Nervous System: General and Special Senses, The Endocrine System, The Cardiovascular System: Blood, The Cardiovascular System: The Heart, The Cardiovascular System: Vessels and Circulation, The Lymphoid System, The Respiratory System, The Digestive System, The Urinary System, The Reproductive System, The Reproductive System: Embryology and HumanDevelopment. MARKET: For all readers interested in human anatomy.