Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.

    Here, nurses remember their first “sticks,” first births, and first deaths, and reflect on what gets them though long, demanding shifts, and keeps them in the profession. The stories reveal many voices from nurses at different stages of their careers: One nurse-in-training longs to be trusted with more “important” procedures, while another questions her ability to care for nursing home residents. An efficient young emergency room nurse finds his life and career irrevocably changed by a car accident. A nurse practitioner wonders whether she has violated professional boundaries in her care for a homeless man with AIDS, and a home care case manager is the sole attendee at a funeral for one of her patients. What connects these stories is the passion and strength of the writers, who struggle against burnout and bureaucracy to serve their patients with skill, empathy, and strength.

    David Livingstone? The New York Times bestselling coauthor of Survivor: The Ultimate Game investigates in this thrilling account.With the utterance of a single line--"Doctor Livingstone, I presume?"--a remote meeting in the heart of Africa was transformed into one of the most famous encounters in exploration history. But the true story behind Dr. David Livingstone and journalist Henry Morton Stanley is one that has escaped telling. Into Africa is an extraordinarily researched account of a thrilling adventure--defined by alarming foolishness, intense courage, and raw human achievement.In the mid-1860s, exploration had reached a plateau. The seas and continents had been mapped, the globe circumnavigated. Yet one vexing puzzle remained unsolved: what was the source of the mighty Nile river? Aiming to settle the mystery once and for all, Great Britain called upon its legendary explorer, Dr. David Livingstone, who had spent years in Africa as a missionary. In March 1866, Livingstone steered a massive expedition into the heart of Africa. In his path lay nearly impenetrable, uncharted terrain, hostile cannibals, and deadly predators. Within weeks, the explorer had vanished without a trace. Years passed with no word.While debate raged in England over whether Livingstone could be found--or rescued--from a place as daunting as Africa, James Gordon Bennett, Jr., the brash American newspaper tycoon, hatched a plan to capitalize on the world's fascination with the missing legend. He would send a young journalist, Henry Morton Stanley, into Africa to search for Livingstone. A drifter with great ambition, but little success to show for it, Stanley undertook his assignment with gusto, filing reports that would one day captivate readers and dominate the front page of the New York Herald.Tracing the amazing journeys of Livingstone and Stanley in alternating chapters, author Martin Dugard captures with breathtaking immediacy the perils and challenges these men faced. Woven into the narrative, Dugard tells an equally compelling story of the remarkable transformation that occurred over the course of nine years, as Stanley rose in power and prominence and Livingstone found himself alone and in mortal danger. The first book to draw on modern research and to explore the combination of adventure, politics, and larger-than-life personalities involved, Into Africa is a riveting read.

    The 1953 American expedition to the second highest peak in the world.

    Applying the same objective criteria to legal and illegal substances, an argument is made that legality is not a clear measure for harm. Tackling a variety of questions, such as Which is more harmful—Ecstasy or alcohol? Can addiction be cured? and Does the "War on Drugs" have serious unintended effects that can hurt children?, this analysis equips readers with the ability to make educated decisions regarding drugs both personally and in their communities. Broadening the scope of the discussion, a framework is explored for formulating national drug policies that will minimize a myriad of harms—social, medical, criminal, financial, and environmental.

    Ratey, MD.Did you know you can beat stress, lift your mood, fight memory loss, sharpen your intellect, and function better than ever simply by elevating your heart rate and breaking a sweat? The evidence is incontrovertible: Aerobic exercise physically remodels our brains for peak performance. In SPARK, John J. Ratey, M.D., embarks upon a fascinating and entertaining journey through the mind-body connection, presenting startling research to prove that exercise is truly our best defense against everything from depression to ADD to addiction to aggression to menopause to Alzheimer's. Filled with amazing case studies (such as the revolutionary fitness program in Naperville, Illinois, which has put this school district of 19,000 kids first in the world of science test scores), SPARK is the first book to explore comprehensively the connection between exercise and the brain. It will change forever the way you think about your morning run---or, for that matter, simply the way you think

    What happens next is downright frightening.Surgery saves Ken’s life but improper care sends him spiraling into madness. Unable to fend for himself, his wife Beth takes charge. She does her best to save him but the unyielding stigma of mental illness hampers his recovery at every turn until he is beyond hope.Desperate to get Ken the help that he needs, Beth makes a heartbreaking decision: she brands the man she loves a “danger to himself and others” and commits him to psychiatric treatment. A police SUV then delivers him to a high-security facility where the real nightmare begins. Plagued by the pitfalls of contemporary psych wards, Ken struggles through living hell. Nevertheless, as the days stretch to weeks, he finds solace by befriending the lost and forgotten and helping patients with worse problems than his.Featured in Amazon Prime Reading and spotlighted as Great on Kindle, Detour from Normal will touch your heart in ways that you never imagined and make you question your faith in our medical and mental health systems.What readers are saying:“A massive amount of emotion rolled into a page-turner.”“An enlightening and dare I say frightening glimpse into the world of mental health care.”“This is a story you will want to share with the people you know and love.”“Scary, life-changing and inspiring!”“Powerful and gripping.”“A psychological thriller, medical mystery, and compelling drama—made all the more vivid because it actually happened.”

    Our ancestors travelled long distances on foot, gaining new experiences and learning from them. But as universal as walking is, each of us will experience it differently. For Erling Kagge, walking is the gateway to the questions that fascinate him--Why do we walk? Where do we walk from? What is our destination?--and in this book he invites us to investigate them along with him. Language reflects the idea that life is one single walk; the word "journey" comes from the distance we travel in the course of a day. Walking for Kagge is a natural accompaniment to science: the occasion for the unspoken dialogue of thinking. Walking is also the antidote to the speed at which we conduct our lives, to our insistence on rushing, on doing everything in a precipitous manner--walking is among the most radical things we can do.

    But it was only when his own son-in the throes of a manic episode-broke into a neighbor's house that he learned what happens to mentally ill people who break a law. This is the Earley family's compelling story, a troubling look at bureaucratic apathy and the countless thousands who suffer confinement instead of care, brutal conditions instead of treatment, in the "revolving doors" between hospital and jail. With mass deinstitutionalization, large numbers of state mental patients are homeless or in jail-an experience little better than the horrors of a century ago. Earley takes us directly into that experience-and into that of a father and award-winning journalist trying to fight for a better way.

    While the dialogue between the gut and the brain has been recognized by ancient healing traditions, including Ayurvedic and Chinese medicine, Western medicine has failed to appreciate the complexity of how the brain, gut, and more recently, the microbiome—the microorganisms that live inside us—communicate with one another. In The Mind-Gut Connection, Dr. Emeran Mayer, executive director of the UCLA Center for Neurobiology of Stress, offers a revolutionary look at this developing science, teaching us how to harness the power of the mind-gut connection to take charge of our health.The Mind-Gut Connection shows how to keep the brain-gut communication clear and balanced to:• heal the gut by focusing on a plant-based diet• balance the microbiome by consuming fermented foods and probiotics, fasting, and cutting out sugar and processed foods• promote weight loss by detoxifying and creating healthy digestion and maximum nutrient absorption• boost immunity and prevent the onset of neurological diseases such as Parkinson’s andAlzheimer’s• generate a happier mindset and reduce fatigue, moodiness, anxiety, and depression• prevent and heal GI disorders such as leaky gut syndrome, food sensitivities and allergies, and IBS, as well as digestive discomfort such as heartburn and bloating• and much more.

    The Lockheed L-188A Electra, on the way from Lima to Pucallpa, flew directly into a thunderstorm. A strike of lightning left the plane incinerated, and Juliane Diller (Koepcke), still strapped to her plane seat, fell through the night air two miles above the Earth. Her survival is unexplainable and considered a modern day miracle. Her mother was among the 91 dead and Juliane the sole survivor. For 11 days she crawled and walked alone through the jungle, fighting for her survival again with hunger and despair her only companions as maggots ate their way into her wounds.Juliane ultimately survived and went on to live an inspiring life as a scientist continually drawn back to the terrain that threatened to take her. On the 40th anniversary, she shares not only the private moments of her survival and rescue but her life in the wake of the dramatic true story.

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

    Four years in the writing, The Breakthrough is an "exciting read" about the discoveries which received the 2018 Nobel Prize winning discoveries in October, and a dramatic and exciting turning point in our relationship with a disease that has for too long defined us.For decades, scientists have puzzled over one of medicine's most confounding mysteries: Why doesn't our immune system recognize and fight cancer the way it does other diseases, like the common cold?As it turns out, the answer to that question can be traced to a series of tricks that cancer has developed to turn off normal immune responses-tricks that scientists have only recently discovered and learned to defeat. The result is what many are calling cancer's "penicillin moment," a revolutionary discovery in our understanding of cancer and how to beat it.In THE BREAKTHROUGH, Graeber guides readers through the revolutionary scientific research bringing immunotherapy out of the realm of the miraculous and into the forefront of twenty-first-century medical science. As advances in the fields of cancer research and the human immune system continue to fuel a therapeutic arms race among biotech and pharmaceutical research centers around the world, the next step-harnessing the wealth of new information to create modern and more effective patient therapies-is unfolding at an unprecedented pace, rapidly redefining our relationship with this all-too-human disease.Groundbreaking, riveting, and expertly told, THE BREAKTHROUGH is the story of the game-changing scientific discoveries that unleash our natural ability to recognize and defeat cancer, as told through the experiences of the patients, physicians, and cancer immunotherapy researchers who are on the front lines. This is the incredible true story of the race to find a cure, a dispatch from the life-changing world of modern oncological science, and a brave new chapter in medical history

    Kaag sets off for the Swiss peaks above Sils Maria where Nietzsche wrote his landmark work Thus Spoke Zarathustra. Both of Kaag's journeys are made in search of the wisdom at the core of Nietzsche's philosophy, yet they deliver him to radically different interpretations and, more crucially, revelations about the human condition.Just as Kaag's acclaimed debut, American Philosophy: A Love Story, seamlessly wove together his philosophical discoveries with his search for meaning, Hiking with Nietzsche is a fascinating exploration not only of Nietzsche's ideals but of how his experience of living relates to us as individuals in the twenty-first century. Bold, intimate, and rich with insight, Hiking with Nietzsche is about defeating complacency, balancing sanity and madness, and coming to grips with the unobtainable. As Kaag hikes, alone or with his family, but always with Nietzsche, he recognizes that even slipping can be instructive. It is in the process of climbing, and through the inevitable missteps, that one has the chance, in Nietzsche's words, to "become who you are."

    Two hours after their jump, all but three of these men were dead or mortally burned from a "blowup" -- an explosive, 2,000-degree firestorm 300 feet deep and 200 feet tall -- a deadly explosion of flame and wind rarely encountered and little understood at the time.  Only seconds ahead of the approaching firestorm, the foreman, R. Wagner Dodge, throws himself into the ashes of an "escape fire " - and survives as most of his confused men run, their last moments obscured by smoke. The parents of the dead cry murder, charging that the foreman's fire killed their boys.  Exactly what happened in Mann Gulch that day has been obscured by years of grief and controversy. Now a master storyteller finally gives the Mann Gulch fire its due as tragedy.     These first deaths among the Forest Service's elite firefighters prompted widespread examination of federal fire policy, of the field of fire science, and of the frailty of young men. For Maclean, who witnessed the fire from the ground in August of 1949,  and even then he knew he would one day become a part of its story.  It is a story of Montana, of the ways of wildfires, firefighters, and fire scientists, and especially of a crew, young and proud, who "hadn't learned to count the odds and to sense they might owe the universe a tragedy." This tale is also Maclean's own, the story of a writer obsessed by a strange and human horror, unable to let the truth die with these young men, searching for the last - and lasting - word. A canvas on which to tell many stories, including the story of his research into the story itself. And finally Nature's violence colliding with human fallibility.      Haunted by these deaths for forty years, Norman Maclean returned to the scene with two of the survivors and pursues the mysteries that Mann Gulch has kept hidden since 1949.  From the words of witnesses, the evidence of history, and the research of fire scientists, Maclean at last assembles the scattered pieces of the Mann Gulch tragedy; in his last work that consumed 14 years of his life, and earned a 1992 National Book Critics Circle Award.       The excruciating detail of this book makes for a sobering reading experience. Maclean -- a former University of Chicago English professor and avid fisherman -- also wrote A River Runs Through It and Other Stories , which is set along the Missouri River, one gulch downstream from Mann Gulch.       "A magnificent drama of writing, a tragedy that pays tribute to the dead and offers rescue to the living.... Maclean's search for the truth, which becomes an exploration of his own mortality, is more compelling even than his journey into the heart of the fire. His description of the conflagration terrifies, but it is his battle with words, his effort to turn the story of the 13 men into tragedy that makes this book a classic."          —  from New York Times Book Review Editor's Choice, Best Books of 1992 The Men who Perished in the Mann Gulch Fire: Robert J. Bennett
Eldon E. Diettert
James O. Harrison
William J. Heilman
Phillip R. McVey
David R. Navon
Leonard L. Piper
Stanley J. Reba
Marvin L. Sherman
Joseph B. Sylvia
Henry J. Thol, Jr.
Newton R. Thompson
Silas R. Thompson Survivors of the Fire: R. Wagner Dodge, foreman
Walter B. Rumsey
Robert W. Sallee