It intersects with Darwin’s theory of evolution, and collides with the horrors of Nazi eugenics in the 1940s. The gene transforms post-war biology. It reorganizes our understanding of sexuality, temperament, choice and free will. This is a story driven by human ingenuity and obsessive minds – from Charles Darwin and Gregor Mendel to Francis Crick, James Watson and Rosalind Franklin, and the thousands of scientists still working to understand the code of codes.This is an epic, moving history of a scientific idea coming to life, by the author of The Emperor of All Maladies. But woven through The Gene, like a red line, is also an intimate history – the story of Mukherjee’s own family and its recurring pattern of mental illness, reminding us that genetics is vitally relevant to everyday lives. These concerns reverberate even more urgently today as we learn to “read” and “write” the human genome – unleashing the potential to change the fates and identities of our children.Majestic in its ambition, and unflinching in its honesty, The Gene gives us a definitive account of the fundamental unit of heredity – and a vision of both humanity’s past and future.

    But what should we change and how do we do it? Annabel Streets and Susan Saunders spent their 30s climbing the career ladder, having children and caring for elderly parents - all at the same time. By their 40s, they were exhausted, stressed, sleeping too little and rushing too much. They began to ask whether the prolonged ill health and dementia suffered by their parents was their inevitable future too - could they do anything to avoid requiring their own children to care for them in old age? Thus began THE AGE-WELL PROJECT. With incredible tenacity, Annabel and Susan read 50,000 scientific research papers on all aspects of ageing to find what advice cutting-edge research can offer us on how to ensure the longer lives we're living are healthy and happy. Putting their findings into practice, they found that the lifestyle changes they made were having incredible benefits on their health and wellbeing now - as well as for the future. Told with empathy and humour, in THE AGE-WELL PROJECT Annabel and Susan share the 50 key lessons they learned, the meals they cooked and the experts' tips they uncovered to make the second half of your life the best half of your life - happy, healthy and disease-free. Author BiographyAnnabel was a founder member of an award-winning marketing company, advising the chief executives of companies such as Sony, Reuters and the Financial Times. After four children, and at breaking point, she sold her company. Following a stint studying photography and producing a community cook book, she changed tack and wrote an award-winning novel The Joyce Girl which sold in 14 countries and was selected for the 2017 Berlin Film Festival. Since then she has written regularly for a range of titles including the Daily Telegraph, Psychologies, The Author, the Guardian, The Irish Times, Elle, Australian

    Over the centuries, cities and governments have risen and fallen beyond the concent's walls. Three times during history's darkest epochs violence born of superstition and ignorance has invaded and devastated the cloistered mathic community. Yet the avout have always managed to adapt in the wake of catastrophe, becoming out of necessity even more austere and less dependent on technology and material things. And Erasmas has no fear of the outside—the Extramuros—for the last of the terrible times was long, long ago.Now, in celebration of the week-long, once-in-a-decade rite of Apert, the fraas and suurs prepare to venture beyond the concent's gates—at the same time opening them wide to welcome the curious "extras" in. During his first Apert as a fraa, Erasmas eagerly anticipates reconnecting with the landmarks and family he hasn't seen since he was "collected." But before the week is out, both the existence he abandoned and the one he embraced will stand poised on the brink of cataclysmic change.Powerful unforeseen forces jeopardize the peaceful stability of mathic life and the established ennui of the Extramuros—a threat that only an unsteady alliance of saecular and avout can oppose—as, one by one, Erasmas and his colleagues, teachers, and friends are summoned forth from the safety of the concent in hopes of warding off global disaster. Suddenly burdened with a staggering responsibility, Erasmas finds himself a major player in a drama that will determine the future of his world—as he sets out on an extraordinary odyssey that will carry him to the most dangerous, inhospitable corners of the planet . . . and beyond.

     2.  Fascinating Memoir:  This book has it all: high stakes gambling, drugs, jail, psychotic episodes and debilitating depression and mental illness, plus the depths of despair and heights of victory.  3.  Very High Profile:  Mike Matusow is one of the most recognizable and followed players in poker today.  Yahoo's online search engine identifies over 1.1 million websites that provide content about Mike Matusow.  His weekly online video show "The Mouthpiece" at CardPlayer.com, averages over 2,000 viewers per day. 4.  Super Popular Subject: Poker is the third most watched sport on cable television, behind auto racing and football. 5.  Secondary Market Possibilities: The National Institute of Mental Health estimates there are 5.7 million people in the U.S. that have bipolar disorder and the CDC estimates 1.6 million elementary school children have been diagnosed ADHD.Get Ready for a Wild Ride… Hang on tight as Mike “The Mouth” Matusow, poker player extraordinaire, takes you with him on a breathtaking, true-life roller coaster ride from his humble beginnings in a trailer park to a rock and roll lifestyle full of hot women, sex, wild drug-filled parties and million-dollar wins and losses. Yet behind the glamour and glory of his high-stakes poker career lurked the flip side: a person torn between two debilitating mental illnesses?—?bipolar disorder and ADHD. To dig himself out of depression and suicidal despair, Matusow turned to dangerous street drugs to self-medicate a problem he didn’t understand, and spiraled deeper into the darker world of addiction, police narcotic stings, and jail time. In this revealing and tumultuous autobiography, the combustible Matusow holds nothing back. You’ll get a mouthful of the man behind the infamous Matusow Meltdowns seen on national TV. Riveting, exhilarating, sexy, sometimes shocking and always fascinating, this voyeur’s look into the world of high-stakes poker, mental illness, and ultimately, Matusow’s inspiring redemption, will keep you glued to your seat until the very last page!

    Lisa Seachrist Chiu has a smorgasbord of stories to tell about rare and not so rare genetic quirks. We read about the Dracula Gene, a mutation in zebra fish that causes blood cells to explode on contact with light, and suites of genes that also influence behavior and physical characteristics; the Tangier Island Gene, first discovered after physicians discovered a boy with orange tonsils (scientists now realize that the child's odd condition comes from an inability to process cholesterol); and Wilson's Disease, a gene defect that fails to clear copper from the body, which can trigger schizophrenia and other neurological symptoms, and can be fatal if left untreated. Friendlier mutations include the Myostatin gene, which allows muscles to become much larger than usual and enhances strength and the much-envied Cheeseburger Gene, which allows a lucky few to eat virtually anything they want and remain razor thin. While fascinating us with stories of genetic peculiarities, Chiu also manages to effortlessly explain much of the cutting-edge research in modern genetics, resulting in a book that is both informative and entertaining. It is a must read for everyone who loves popular science or is curious about the human body.

    Essentially, you make an initial guess, and then get more data to improve it. Bayes Theorem, or Bayes Rule, has a ton of real world applications, from estimating your risk of a heart attack to making recommendations on Netflix But It Isn't That Complicated This book is a short introduction to Bayes Theorem. It is only 15 pages long, and is intended to show you how Bayes Theorem works as quickly as possible. The examples are intentionally kept simple to focus solely on Bayes Theorem without requiring that the reader know complicated probability distributions. If you want to learn the basics of Bayes Theorem as quickly as possible, with some easy to duplicate examples, this is a good book for you.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    Evo Devo Evolutionary Developmental Biology is the new science that has finally cracked open the box. Within the pages of his rich and riveting book, Sean B. Carroll explains how we are discovering that complex life is ironically much simpler than anyone ever expected.

    Theory has been provided in points between each chapter for clarifying relevant basic concepts. The book consist four parts algebra and trigonometry, fundamentals of analysis, geometry and vector algebra and the problems and questions set during oral examinations. Each chapter consist topic wise problems. Sample examples are provided after each text for understanding the topic well. The fourth part "oral examination problems and question" includes samples suggested by the higher schools for the help of students. Answers and hints are given at the end of the book for understanding the concept well. About the Book: Problems in Mathematics with Hints and Solutions Contents: Preface Part 1. Algebra, Trigonometry and Elementary Functions Problems on Integers. Criteria for Divisibility Real Number, Transformation of Algebraic Expressions Mathematical Induction. Elements of Combinatorics. BinomialTheorem Equations and Inequalities of the First and the SecondDegree Equations of Higher Degrees, Rational Inequalities Irrational Equations and Inequalities Systems of Equations and Inequalities The Domain of Definition and the Range of a Function Exponential and Logarithmic Equations and Inequalities Transformations of Trigonometric Expressions. InverseTrigonometric Functions Solutions of Trigonometric Equations, Inequalities and Systemsof Equations Progressions Solutions of Problems on Derivation of Equations Complex Numbers Part 2. Fundamentals of Mathematical Analysis Sequences and Their Limits. An Infinitely Decreasing GeometricProgression. Limits of Functions The Derivative. Investigating the Behaviors of Functions withthe Aid of the Derivative Graphs of Functions The Antiderivative. The Integral. The Area of a CurvilinearTrapezoid Part 3. Geometry and Vector Algebra Vector Algebra Plane Geometry. Problems on Proof Plane Geometry. Construction Problems Plane Geometry. C

    With the addition of new chapters, thorough updating, and a new co-author, this latest edition represents the definitive introduction to behavioral genetics: the crossroads where the fields of psychology, psychiatry, and genetics intersect.

    Contrary to what the glossy magazines would have us believe, we do not enjoy potato chips because they crunch just like the insects our forebears snacked on. As Zuk argues, such beliefs incorrectly assume that we’re stuck—finished evolving—and have been for tens of thousands of years. She draws on fascinating evidence that examines everything from adults’ ability to drink milk to the texture of our ear wax to show that we’ve actually never stopped evolving. Our nostalgic visions of an ideal evolutionary past in which we ate, lived, and reproduced as we were “meant to” fail to recognize that we were never perfectly suited to our environment. Evolution is about change, and every organism is full of trade-offs.From debunking the caveman diet to unraveling gender stereotypes, Zuk gives an analysis of widespread paleofantasies and the scientific evidence that undermines them, all the while broadening our understanding of our origins and what they can really tell us about our present and our future.

    Now, faced with the threat of nuclear weapons and the effects of climate change, it seems our innate tendencies for violence and invention have led us to a crucial fork in our road. Where did these traits come from? Are they part of our species immutable destiny? Or is there hope for our species’ future if we change? With fascinating facts and his unparalleled readability, Diamond intended his book to improve the world that today’s young people will inherit. Triangle Square’s The Third Chimpanzee for Young People is a book for future generation and the future they’ll help build.

    Dozens of examples in innumeracy show us how it affects not only personal economics and travel plans, but explains mis-chosen mates, inappropriate drug-testing, and the allure of pseudo-science.

    Wilczek’s groundbreaking work in quantum physics was inspired by his intuition to look for a deeper order of beauty in nature. In fact, every major advance in his career came from this intuition: to assume that the universe embodies beautiful forms, forms whose hallmarks are symmetry—harmony, balance, proportion—and economy. There are other meanings of “beauty,” but this is the deep logic of the universe—and it is no accident that it is also at the heart of what we find aesthetically pleasing and inspiring.Wilczek is hardly alone among great scientists in charting his course using beauty as his compass. As he reveals in A Beautiful Question, this has been the heart of scientific pursuit from Pythagoras, the ancient Greek who was the first to argue that “all things are number,” to Galileo, Newton, Maxwell, Einstein, and into the deep waters of twentiethcentury physics. Though the ancients weren’t right about everything, their ardent belief in the music of the spheres has proved true down to the quantum level. Indeed, Wilczek explores just how intertwined our ideas about beauty and art are with our scientific understanding of the cosmos.Wilczek brings us right to the edge of knowledge today, where the core insights of even the craziest quantum ideas apply principles we all understand. The equations for atoms and light are almost literally the same equations that govern musical instruments and sound; the subatomic particles that are responsible for most of our mass are determined by simple geometric symmetries. The universe itself, suggests Wilczek, seems to want to embody beautiful and elegant forms. Perhaps this force is the pure elegance of numbers, perhaps the work of a higher being, or somewhere between. Either way, we don’t depart from the infinite and infinitesimal after all; we’re profoundly connected to them, and we connect them. When we find that our sense of beauty is realized in the physical world, we are discovering something about the world, but also something about ourselves.Gorgeously illustrated, A Beautiful Question is a mind-shifting book that braids the age-old quest for beauty and the age-old quest for truth into a thrilling synthesis. It is a dazzling and important work from one of our best thinkers, whose humor and infectious sense of wonder animate every page. Yes: The world is a work of art, and its deepest truths are ones we already feel, as if they were somehow written in our souls.

    Jason Fung returns with an eye-opening biography of cancer in which he offers a radical new paradigm for understanding cancer—and issues a call to action for reducing risk moving forward. Our understanding of cancer is slowly undergoing a revolution, allowing for the development of more effective treatments. For the first time ever, the death rate from cancer is showing a steady decline . . . but the “War on Cancer” has hardly been won.In The Cancer Code, Dr. Jason Fung offers a revolutionary new understanding of this invasive, often fatal disease—what it is, how it manifests, and why it is so challenging to treat. In this rousing narrative, Dr. Fung identifies the medical community’s many missteps in cancer research—in particular, its focus on genetics, or what he terms the “seed” of cancer, at the expense of examining the “soil,” or the conditions under which cancer flourishes. Dr. Fung—whose groundbreaking work in the treatment of obesity and diabetes has won him international acclaim—suggests that the primary disease pathway of cancer is caused by the dysregulation of insulin. In fact, obesity and type 2 diabetes significantly increase an individual’s risk of cancer.In this accessible read, Dr. Fung provides a new paradigm for dealing with cancer, with recommendations for what we can do to create a hostile soil for this dangerous seed. One such strategy is intermittent fasting, which reduces blood glucose, lowering insulin levels. Another, eliminating intake of insulin-stimulating foods, such as sugar and refined carbohydrates.For hundreds of years, cancer has been portrayed as a foreign invader we’ve been powerless to stop. By reshaping our view of cancer as an internal uprising of our own healthy cells, we can begin to take back control. The seed of cancer may exist in all of us, but the power to change the soil is in our hands.