Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

    The result is an explosive book that takes us, for the first time, deep inside a shadowy, fascinating, and surreal world of unscrupulous doctors, anything-goes team directors, and athletes so relentlessly driven to succeed that they would do anything—and take any risk, physical, mental, or moral—to gain the edge they need to win.Tyler Hamilton was once one of the world’s best-liked and top-ranked cyclists—a fierce competitor renowned among his peers for his uncanny endurance and epic tolerance for pain. In the 2003 Tour de France, he finished fourth despite breaking his collarbone in the early stages—and grinding eleven of his teeth down to the nerves along the way. He started his career with the U.S. Postal Service team in the 1990s and quickly rose to become Lance Armstrong’s most trusted lieutenant, and a member of his inner circle. For the first three of Armstrong’s record seven Tour de France victories, Hamilton was by Armstrong’s side, clearing his way. But just weeks after Hamilton reached his own personal pinnacle—winning the gold medal at the 2004 Olympics—his career came to a sudden, ignominious end: He was found guilty of doping and exiled from the sport.From the exhilaration of his early, naïve days in the peloton, Hamilton chronicles his ascent to the uppermost reaches of this unforgiving sport. In the mid-1990s, the advent of a powerful new blood-boosting drug called EPO reshaped the world of cycling, and a relentless, win-at-any-cost ethos took root. Its psychological toll would drive many of the sport’s top performers to substance abuse, depression, even suicide. For the first time ever, Hamilton recounts his own battle with clinical depression, speaks frankly about the agonizing choices that go along with the decision to compete at a world-class level, and tells the story of his complicated relationship with Lance Armstrong.A journey into the heart of a never-before-seen world, The Secret Race is a riveting, courageous act of witness from a man who is as determined to reveal the hard truth about his sport as he once was to win the Tour de France.

    The killer went to great lengths to cover up her crime including sending his grandmother flowers, going to the memorial service, driving by the victim’s house and calling the lead investigator, Detective Esteban Flores. This incident took place in a suburb of Phoenix, Arizona. It would be five years before this case of capital murder would be put in front of a jury to decide the fate of Jodi Arias although the fate of Travis Alexander had been set in stone. Was she a cold, calculating murderess or was she a victim of extreme domestic violence at the hands of an abusive boyfriend? The first jury was left to decide in 2013. It was the most watched trial of the century. The jury decided that Jodi Arias was guilty of first-degree murder with cruel and heinous circumstances which qualified her for the death penalty. The jury could not reach a decision in the penalty phase and justice was delayed. A new jury, drawn from a pool of four hundred people, was drawn for the highly anticipated retrial of Jodi Arias. On October 21, 2014, a jury of nineteen was given the responsibility of deciding whether Jodi Arias should live or die for her crime. So began a retrial that would last almost five months with Juan Martinez and Detective Flores representing the State of Arizona and the return of Kirk Nurmi and Jennifer Willmott speaking to the defense of the convicted killer. The journey will walk the reader through the meticulous actions of the courtroom and extend to an appellate court, a municipal court and a day in the in the original courthouse in phoenix, Arizona. The trial speaks toward the long arm of the law and the implications of decisions made daily. With the help of former jurors of the Jodi Arias death penalty retrial, the reader will step into the jury box when Jodi Arias was on the witness stand and reach a climax when the reader accompanies the jury foreman into the deliberation room as the jury decides the fate of the defendant. “The lambs to the law were now executors of the law. It was humbling, intimidating and powerful at the same time. It was also the time that the jurors’ souls would be tested for truths and experiences that would mark many discussions in the deliberation room. The jury would remember Travis Alexander and what was done to him.” Why Not Kill her is the suspenseful follow-up to the authors first book, Brain Damage: A Juror’s Tale, the true story of being a death penalty juror on the case of Marissa DeVault and the brutal killing of Dale Harrell. The third revised edition is now available in honor of Dale Harrell. Take a journey into the life of Travis Alexander and a search for truth and justice. Somehow, Lady Justice will wield her sword and the end of a seven year saga would be realized but in no way that anyone could have anticipated. Special thanks to True Crime Radio, Trial Talk Live, the Trial Diaries, FOX 10, ABC, NBC and CBS. The author would also like to thank those who supported this work on Go Fund Me with extra recognition to the administrators and fans of Juan Martinez Prosecutor Support Page, The State vs. Jodi Arias, Joey Jackson Fan Page, Justice For Travis, Justice 4 Dale, Justice For Travis Alexander and His Family, Court Chatter, Beth Karas on Crime, Gavel geeks, Trial Watchers, The House That Travis Built, Understanding The Travesties of Unexpected Murder Trials and For The Love of Travis. This work could not have happened without your support! Why Not Kill Her is dedicated to Travis Alexander, his family and all those whom he touched in his short life.

    Drawing on personal anecdotes, meeting, off-the record conversations with Benazir Bhutto, and the emails that he exchanged with her just before her death, Amir Mir, one of Pakistan's leading investigative journalist, brings us a carefully documented reconstruction of the assassination that rocked the world.

    Now #1 New York Times bestselling author Dr. Nicholas Perricone gives us an anti-aging program that unveils the miracle of cellular rejuvenation. These seven powerful strategies are not only easy to follow but present a plan for total health designed to help us look and feel great by age-proofing us from the inside out. Taking a holistic approach that taps into cutting-edge science, Dr. Nicholas Perricone reveals how to rev up our cellular metabolism so that we can stay healthy, strong, and energetic, while keeping our skin soft, smooth, and supple. These strategies will help us reverse osteoporosis, restore bone structure and muscle mass, revitalize brain cells, reduce the chances of heart disease and cancer, elevate mood, manage blood sugar, and slim down and stay trim. Inside Dr. Perricone’s 7 Secrets to Beauty, Health, and Longevity you will discover• the six kinds of food you need to eat every day, as well as healthy and delicious snacks–including a vegetable that both suppresses appetite and builds muscle• new findings about the best nutritional supplements to win the fight against aging• revolutionary skin rejuvenating secrets for radiant, toned, and youthful-looking skin • the role of pheromones in curbing depression, boosting self-confidence, triggering weight loss, and improving libido• the essential oil that is more powerful than antibiotics• an exercise plan that will shape your silhouette and strengthen your bones in as little as ten minutes a day• delicious recipes, easy shopping lists, and a guide to safe cookware so that you can create your own anti-aging kitchen• Dr. Perricone’s trademark tips about new products that really work–and where to find themWhether your aim is to look younger, improve your health, or just feel great, you’ll see fast results by following Dr. Perricone’s simple program. These seven indispensable secrets will keep you beautiful, healthy, and young all through life.From the Hardcover edition.

    After a sensational trial, she was sentenced to die by lethal injection, and fifteen years later, on February 24, 2000, she was executed.

     Police begin to suspect that their target is a rogue operator who has emerged from their own ranks. And then, all hell breaks loose in Los Angeles… An arrest in the strangling murders of two co-eds across state lines finally leads to a break in the case, but the mild-mannered suspect remembers nothing about the crime of which he is accused. His attorney and a team of psychiatrists are convinced this is no lust murderer, but a mentally ill man tormented by an evil alter personality, the terrifyingly malevolent sexual sadist “Steve”. But what if Steve is the final triumphant act in a psychopath’s lifelong career in deception? None are prepared for the dark journey through the mazes of the human mind it will take to unlock the door to justice. From the author of the aviation disaster ebook bestseller “Gone: Catastrophe in Paradise”, “A City Owned” is the first installment of the two-part series “Murder by Increments”, the true story of the worst case of serial sex homicide in American history.

    Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness.In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone.Along the way he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome--the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they're more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin to how we smell. The new goal of skin care will be to cultivate a healthy biome--and to embrace the meaning of "clean" in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process.Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

    or did she?Lizzie Borden is a name that has lived in infamy. As everyone knows, she's the young woman who "took an axe and gave her mother 40 whacks" and then "gave her father 41." Everyone seems to know the rhyme, but most people don't know the truth behind the grim story of one of America's most famous unsolved murders. In this new entry in the "Dead Men Do Tell Tales" series, author Troy Taylor delves into the true story of the Borden Murders, revealing what really happened on that morning in August 1892, how Lizzie was hounded by the police, prosecutors, and reporters, and then finally acquitted - yet always believed to be guilty. Was she a murderer or truly innocent? Did she swing the hatchet that killed her parents, or was Lizzie simply part of a plot that accidentally led to murders committed by a madman? You'll have the chance to decide for yourself as the suspects are revealed, the conspiracies unveiled, and the strange circumstances of this haunting case are presented. Forget everything you already think you know about this compelling case and discover what did - and what did not - happen in the story of Lizzie Borden! What dark secrets have never been told? What happened in the grim aftermath of the murder trial? Do the spirits of the dead still linger in the house where the Bordens were killed? You'll find these answers and more and you'll never look at this chilling story in the same way again!

    The secret, though, that surrounded my parents’ unhappy life together, was divulged to me by accident . . .’ Hidden under some papers in his father’s bureau, the sixteen-year-old Derek Malcolm finds a book by the famous criminologist Edgar Lustgarten called The Judges and the Damned. Browsing through the Contents pages Derek reads, ‘Mr Justice McCardie tries Lieutenant Malcolm – page 33.’ But there is no page 33. The whole chapter has been ripped out of the book. Slowly but surely, the shocking truth emerges: that Derek’s father, shot his wife’s lover and was acquitted at a famous trial at the Old Bailey. The trial was unique in British legal history as the first case of a crime passionel, where a guilty man is set free, on the grounds of self-defence. Husband and wife lived together unhappily ever after, raising Derek in their wake. Then, in a dramatic twist, following his father’s death, Derek receives an open postcard from his Aunt Phyllis, informing him that his real father is the Italian Ambassador to London . . . By turns laconic and affectionate, Derek Malcolm has written a richly evocative memoir of a family sinking into hopeless disrepair. Derek Malcolm was chief film critic of the Guardian for thirty years and still writes for the paper. Educated at Eton and Merton College, Oxford, he became first a steeplechase rider and then an actor after leaving university. He worked as a journalist in the sixties, first in Cheltenham and then with the Guardian where he was a features sub-editor and writer, racing correspondent and finally film critic. He directed the London Film Festival for a spell in the 80s and is now President of both the International Film Critics Association and the British Federation of Film Societies. He lives with his wife Sarah Gristwood in London and Kent and has published two books – one on Robert Mitchum and another on his favourite 100 films. He is a frequent broadcaster on radio and television and a veteran of film festival juries all over the world.

    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

    Despite his family’s strong republican ties and his own attempt to join the IRA, Hartnett shocked family and friends when he changed allegiance and joined the British Armed Forces. In 2001 Hartnett returns to his native Ireland, but this time as a member of the British Army’s most secretive covert counter-terrorist unit in Northern Ireland, Joint Communications Unit Northern Ireland aka JCU-NI, the FRU, 14 Intelligence Company, or simply ‘The Det’. For the next three years Hartnett is directly involved in some of the highest profile events of that period, from the arrest of John Hannan for the bombing of the BBC in London, to the tragic murder of David Caldwell; the prevention of the murder of Johnny ‘Mad Dog’ Adair and some of the biggest blunders by British Intelligence in the history of the Troubles, including the true story behind the murders of Corporals Howes and Wood at an IRA funeral in 1988. ‘Charlie One’, the call sign for the most wanted targets of British Intelligence operations in NI, documents the journey of an Irish Republican serving in Britain’s most secretive counter-terrorism unit. Filled with roller coaster emotions and explosive revelations of British Intelligence covert capabilities and operations, Charlie One provides a truly unique, detailed and unbiased account of the secret war fought on the streets of Northern Ireland.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    

    Like when doctors prescribed morphine for crying infants. When snorting skull moss was a cure for a bloody nose. When consuming mail-order tapeworms was a latter-day fad diet. Or when snake oil salesmen peddled strychnine (used in rat poison) as an aphrodisiac in the '60s. Seamlessly combining macabre humor with hard science and compelling storytelling, Quackery is a visually rich and information-packed exploration of history's most outlandish cures, experiments, and scams.A humorous book that delves into some of the wacky but true ways that humans have looked to cure their ills. Leeches, mercury, strychnine, and lobotomies are a few of the topics that explore the lengths society has gone in the search for health.