As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    Psych 101 cuts out the boring details and statistics, and instead, gives you a lesson in psychology that keeps you engaged - and your synapses firing.From personality quizzes and the Rorschach Blot Test to B.F. Skinner and the stages of development, this primer for human behavior is packed with hundreds of entertaining psychology basics and quizzes you can't get anywhere else.So whether you're looking to unravel the intricacies of the mind, or just want to find out what makes your friends tick, Psych 101 has all the answers - even the ones you didn't know you were looking for.

    Chosen from hundreds of crackerjack pilots for their fitness, intelligence & courage, the original Mercury Seven astronauts risked their lives to cross the space frontier. In We Seven they take readers behind the scenes to show them their training, technology & teamwork, & to share personal stories, including the lighter moments of their mission. They bring readers inside the Mercury program, even into the space capsules themselves. We Seven straps you in with the astronauts & rockets you along for the ride. Share Alan Shepard's exhilaration as he breaks thru the earth's atmosphere. Endure moments of panic with Gus Grissom when his hatch blows, stranding him in the open sea. Race with John Glenn as he makes split-second life-or-death maneuvers during reentry, & feel his relief when he emerges safe but drenched with sweat. Despite such heroism, Project Mercury was more than the story of individual missions. It defined the manned space flight program to come, from Gemini thru Apollo. In We Seven America's original astronauts tell us 1sthand about the space program they pioneered, & share with us the hopes of the USA at the dawn of a new era.

    Since its creation in 2010, Instagram’s fun and simple interface has captured our collective imagination, swiftly becoming a way of life. In No Filter: The Inside Story of Instagram, technology reporter Sarah Frier explains how Instagram’s founders married art and technology to overcome skeptics and to hook the public on visual storytelling. At first, Instagram initially attracted artisans, but then the platform exploded in popularity among the masses, creating an entire industry of digital influencers that’s now worth tens of billions of dollars. Eighteen months after Instagram’s launch and explosive growth, the founders—Kevin Systrom and Mike Krieger—made the gut-wrenching decision to sell the company to Facebook. For most companies, that would be the end of the story; but for Instagram, it was only the beginning. Instagram borrowed some lessons from Facebook and rejected others, until eventually its success stirred tension with Facebook’s CEO Mark Zuckerberg, just as Facebook became embroiled in a string of public crises. Frier unearths the details that led to the cofounders’ departure, bringing to light dramatic moments unknown to the public until now. At its heart, No Filter draws on unprecedented exclusive access—from the founders of Instagram, as well as employees, executives, and competitors; hedge fund billionaire Ray Dalio; Anna Wintour of Vogue; Kris Jenner of the Kardashian-Jenner empire; and a plethora of influencers, from fashionistas with millions of followers to owners of famous dogs worldwide—to show how Instagram has fundamentally changed the way we communicate, shop, eat, and travel. The book brings readers inside users’ strategies to craft their personal image and fame, explaining how the company’s product decisions have affected the structure of our society. From teenagers to the pope, No Filter tells the captivating story of how Instagram not only created a new industry but also changed our lives.

    These are her collected pieces: regular bulletins from the woman writing under the covers.Marian loves shoes and her LTFs (Long-Term Friends), hates realtors and lost luggage, and she once had a Christmas office party that involved roasting two sheep on a spit, Moroccan-style. She's just like you and me ...Featuring a wide compilation of Marian's journalism from magazines and newspapers, plus some exclusive, previously unpublished material, Under the Duvet is bursting with funny stories: observations on life, in-laws, weight loss, parties and driving lessons that will keep you utterly gripped -- either wincing with recognition or roaring with laughter.

    In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a training group on my team could consist of five men who run next to one another, stride for stride, day after day, and nonetheless turn out five entirely different runners. How could this be?We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. Naturals. Or were they?The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training?The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research.In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called 10,000-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence.Along the way, Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not, and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components.This subject necessarily involves digging deep into sensitive topics like race and gender. Epstein explores controversial questions such as:Are black athletes genetically predetermined to dominate both sprinting and distance running, and are their abilities influenced by Africa’s geography?Are there genetic reasons to separate male and female athletes in competition?Should we test the genes of young children to determine if they are destined for stardom?Can genetic testing determine who is at risk of injury, brain damage, or even death on the field?Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

    It can give us an understanding of lives very different from our own, and a sense of the shared joys and losses of human experience." Readers will discover novels and memoirs by some of the most gifted writers working today; favorite classics worth reading or rereading; and nonfiction works, both old and new, that illuminate our social and political landscape and some of today’s most pressing issues, from climate change to medicine to the consequences of digital innovation. There are essential works in American history (The Federalist Papers, The Writings and Speeches of Martin Luther King, Jr.); books that address timely cultural dynamics (Elizabeth Kolbert's The Sixth Extinction, Margaret Atwood's The Handmaid's Tale); classics of children's literature (the Harry Potter novels, Where the Wild Things Are); and novels by acclaimed contemporary writers like Don DeLillo, William Gibson, Chimamanda Ngozi Adichie, and Ian McEwan.With richly detailed illustrations by lettering artist Dana Tanamachi that evoke vintage bookplates, Ex Libris is an impassioned reminder of why reading matters more than ever.

    A Papua New Guinean elder shoves off in his hand-carved canoe, ready to summon a shark with ancient magic. A scientist finds a rare shark in Indonesia and forges a deal with villagers so it and other species can survive.In this eye-opening adventure that spans the globe, Juliet Eilperin investigates the fascinating ways different individuals and cultures relate to the ocean’s top predator. Along the way, she reminds us why, after millions of years, sharks remain among nature’s most awe-inspiring creatures.From Belize to South Africa, from Shanghai to Bimini, we see that sharks are still the object of an obsession that may eventually lead to their extinction. This is why movie stars and professional athletes go shark hunting in Miami and why shark’s fin soup remains a coveted status symbol in China. Yet we also see glimpses of how people and sharks can exist alongside one another: surfers tolerating their presence off Cape Town and ecotourists swimming with sharks that locals in the Yucatán no longer have to hunt.With a reporter’s instinct for a good story and a scientist’s curiosity, Eilperin offers us an up-close understanding of these extraordinary, mysterious creatures in the most entertaining and illuminating shark encounter you’re likely to find outside a steel cage.

    Most of the time this math works quietly behind the scenes . . . until it doesn't. All sorts of seemingly innocuous mathematical mistakes can have significant consequences.Math is easy to ignore until a misplaced decimal point upends the stock market, a unit conversion error causes a plane to crash, or someone divides by zero and stalls a battleship in the middle of the ocean.Exploring and explaining a litany of glitches, near misses, and mathematical mishaps involving the internet, big data, elections, street signs, lotteries, the Roman Empire, and an Olympic team, Matt Parker uncovers the bizarre ways math trips us up, and what this reveals about its essential place in our world. Getting it wrong has never been more fun.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    From countries and cities to toys and animals to even planets, learn the etymology of interesting words in a fun and entertaining way.Learn new things: Why is New York called New York? The Origin of Names, Words and Everything in Between has the answer for you. While author Patrick Foote, of the YouTube channel also called Name Explain, doesn’t claim to know everything, he has garnered a lot of knowledge about language over the years and he’s excited to get to share it with you in this new format.Be entertained by education: Learning doesn’t have to be boring. With his fun sense of humor, Patrick explains each name with jokes and quips you’re bound to enjoy. Full of pictures and packed with great information, The Origin of Names, Words and Everything in Between has a variety of topics that are bound to intrigue anyone interested in the origins of the words we use every day.Find fun facts: The Origin of Names, Words and Everything in Between is full of interesting facts that are great to keep in your mental pocket. You’ll be able to pull out fun information about words and language all the time, informing and amusing yourself and your friends for ages.The Origin of Names, Words and Everything in Between does exactly what it says it does—it explains the origin of names in a fun and easy-to-digest way. After reading this book, you will: Know why, exactly, Russia is called Russia Be able to entertain yourself and your friends with interesting fun facts Discover the origins of the names of planets, animals, countries, and much more

    At first I tried to deny my condition (trying to treat a tumor with hot baths and ice packs). Eventually, I decided I would learn as much about my illness as possible while trying to keep my emotions on hold.What followed was an experience that finally forced me to deal with issues about my body that I had tried to ignore for decades. Along the way I dealt with a physician who gave me ridiculous advice and acquaintances who asked unbelievable questions. But I was also fortunate to be surrounded by people who supported me and doctors who helped me through the process.

    In the Dam Square in Amsterdam, long-haired young people wearing vibrant clothes and burning incense could be found meditating, playing music and discussing sexual liberation, the expansion of consciousness and the search for an inner truth. They were a generation refusing to live the robotic and unquestioning life that their parents had known.At this time, Paulo is a young, skinny Brazilian with a goatee and long, flowing hair who wants to become a writer. He sets off on a journey in search of freedom and a deeper meaning for his life: first, with a girlfriend, on the famous “Death Train to Bolivia,” then on to Peru and later hitchhiking through Chile and Argentina.His travels take him further, to the famous square in Amsterdam, where Paulo meets Karla, a Dutch woman also in her 20s. She convinces Paulo to join her on a trip to Nepal, aboard the Magic Bus that travels across Europe and Central Asia to Kathmandu. They embark on a journey in the company of fascinating fellow travelers, each of whom has a story to tell, and each of whom will undergo a transformation, changing their priorities and values, along the way. As they travel together, Paulo and Karla explore their own relationship, an awakening on every level that brings each of them to a choice and a decision that sets the course for their lives thereafter.

    In "elegant, finely honed prose" (The Washington Post Book World), Lebowitz limns the vicissitudes of contemporary urban life—its fads, trends, crazes, morals, and fashions. By turns ironic, facetious, deadpan, sarcastic, wry, wisecracking, and waggish, she is always wickedly entertaining.