Left untouched were many of the things known to cause cancer, including tobacco, the workplace, radiation, or the global environment. Proof of how the world in which we live and work affects whether we get cancer was either overlooked or suppressed. This has been no accident. The War on Cancer was run by leaders of industries that made cancer-causing products, and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies-a legacy that persists to this day. This is the gripping story of a major public health effort diverted and distorted for private gain. A portion of the profits from this book will go to support research on cancer prevention.

    This hidden army is our immune system, and without it we could not survive the eternal war between us and our microscopic enemies.Immune explores the incredible arsenal that lives within us how it knows what to attack and what to defend, and how it kills everything from the common cold to the plague bacterium. We see what happens when the immune system turns on us, and conversely how impossible life is without its protection. We learn how diseases try to evade the immune system, how they exploit vulnerabilities and even subvert it to their own advantage, and we discover how scientists are designing new drugs to harness the power of the system to advance medicine in the 21st century.Some of the topics explored include why are so many people allergic to cats, but so few to hamsters? Do transplants ever reject their new bodies? What is pus? How does your body develop new weapons for new enemies? Why is cancer so hard for our immune system to fight? How does our immune system remember? Why did the 1918 flu pandemic kill mainly young, healthy people? Why did the 2009 swine flu outbreak lead to a spike in sleep disorders? Can we smell someone else's immune system? And does that help us subconsciously decide who we fall in love with?Immune provides an entertaining, intriguing and accessible account of the body's defenses against disease. Drawing on everything from ancient Egyptian medical texts to cutting-edge medical science, the book takes readers on an adventure packed with weird and wonderful facts about their own defense mechanisms, making this both informative and great fun to read.

     Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

    The shocking story of blinded eyes, and the medical school that allowed it.

    Soon Gen Xers will be the only cohort of Americans who remember life as it was lived before the arrival of the Internet. They are, as Hennessey dubs them, “the last adult generation,” the sole remaining link to a time when childhood was still a bit dangerous but produced adults who were naturally resilient. More than a decade into the social media revolution, the American public is waking up to the idea that the tech sector’s intentions might not be as pure as advertised. The mountains of money being made off our browsing habits and purchase histories are used to fund ever-more extravagant and utopian projects that, by their very natures, will corrode the foundations of free society, leaving us all helpless and digitally enslaved to an elite crew of ultra-sophisticated tech geniuses. But it’s not too late to turn the tide. There’s still time for Gen X to write its own future. A spirited defense of free speech, eye contact, and the virtues of patience, Zero Hour for Gen X is a cultural history of the last 35 years, an analysis of the current social and historical moment, and a generational call to arms.

    Six years later she made her first suicide attempt, then wandered the streets of New York City dressed in ragged clothes, tormenting voices crying out in her mind. Lori Schiller had entered the horrifying world of full-blown schizophrenia. She began an ordeal of hospitalizations, halfway houses, relapses, more suicide attempts, and constant, withering despair. But against all odds, she survived. Now in this personal account, she tells how she did it, taking us not only into her own shattered world, but drawing on the words of the doctors who treated her and family members who suffered with her.In this new edition, Lori Schiller recounts the dramatic years following the original publication -- a period involving addiction, relapse, and ultimately, love and recovery.Moving, harrowing, and ultimately uplifting, THE QUIET ROOM is a classic testimony to the ravages of mental illness and the power of perseverance and courage.

    health care system is in a state of disrepair, but the rabbit hole goes deeper than even the staunchest critics may realize. In Primal Prescription, authors Doug McGuff and Robert Murphy combine their expertise in economics and medicine to offer a shocking, disturbing, and ultimately enlightening view into America’s health care system. You’ll discover the real history of what went wrong with U.S. health care and insurance, and why current efforts to clean up the mess are only making things worse.But far from leaving you feeling helpless at the dismal—and sometimes deadly—state of affairs, Primal Prescription equips you with both the knowledge to understand the health care conundrum and the tools for navigating your way out of it. McGuff and Murphy offer an evidence-based “game plan” for taking control of your own medical care, protecting yourself and your loved ones regardless of what the future holds for the rest of the nation.Whether you’re currently tangled in America’s broken health care system or simply trying to avoid its clutches, Primal Prescription is a must-have resource for taking your health into your own hands.

    Between the shopping trips and the doctor visits with Grandpa, Gabe and his friend John try to salvage their senior year, meet girls, and make the varsity baseball team. It doesn’t take long for Gabe to realize that going to school and looking after a grandfather with Alzheimer’s is more work than he ever imagined. And when long-lost Uncle Nick appears on the scene, Gabe soon finds that living with Nick and Grandpa is like babysitting two grown men. Aside from John, the only person who truly understands Gabe is Sofia, a punk-rocking rebel he meets at the veteran’s hospital. When these three unlikely friends are faced with a serious dilemma, will they do what it takes to save Grandpa? If there’s a chance of preserving the final shreds of Grandpa’s dignity, Gabe may have to make the most gut-wrenching decision of his life—and there’s no way out.

    The fastest-growing segment of the population, those beyond the age of fifty, are no longer content to simply cope with the losses of age. Mental acuity and vitality are becoming a life-long pursuit. Now, the science of the mind is catching up with the Baby Boom generation. In this landmark book, renowned psychiatrist Gene Cohen challenges the long-held belief that our brain power inevitably declines as we age, and shows that there are actually positive changes taking place in our minds. Based on the latest studies of the brain, as well as moving stories of men and women in the second half of life, The Mature Mind reveals for the first time how we can continue to grow and flourish. Cohen's groundbreaking theory-the first to elaborate on the psychology of later life-describes how the mind gives us "inner pushes" and creates new opportunities for positive change throughout adult life. He shows how we can jump-start that growth at any age and under any circumstances, fine-tuning as we go, actively building brain reserves and new possibilities. The Mature Mind offers a profoundly different and intriguing look at ourselves, challenging old assumptions, raising bold new questions, and providing exciting answers grounded in science and the realities of everyday life.

    The book also includes bonus content to help you get started coding!Fans of funny and inspiring books like Maya Van Wagenen’s Popular and Caroline Paul’s Gutsy Girl will love hearing about Andrea “Andy” Gonzales and Sophie Houser’s journey from average teens to powerhouses. Through the success of their video game, Andy and Sophie got unprecedented access to some of the biggest start-ups and tech companies, and now they’re sharing what they’ve seen. Their video game and their commitment to inspiring young women have been covered by the Huffington Post, Buzzfeed, CNN, Teen Vogue, Jezebel, the Today show, and many more.Get ready for an inside look at the tech industry, the true power of coding, and some of the amazing women who are shaping the world. Andy and Sophie reveal not only what they’ve learned about opportunities in science and technology but also the true value of discovering your own voice and creativity.

    The public was outraged. The game had reached a make-or-break moment--fourth down and inches. Coaches, players, fans, and even the president of the United States had one last chance: change football or leave the field. Football's defenders managed to move the chains. Rule changes and reforms after 1905 saved the game and cleared the way for it to become America's most popular sport. But they didn't fix everything. Today, football faces a new injury crisis as dire as 1905's. With increased awareness about brain injury, reported concussions are on the rise among football players. But experts fear concussions may only be the tip of the iceberg. The injuries are almost invisible, but the stakes couldn't be higher: the brains of millions of young football players across the country. Award-winning author Carla Killough McClafferty takes readers on a bone-crunching journey from football's origins to the latest research on concussion and traumatic brain injuries in the sport. Fourth Down and Inches features exclusive photography and interviews with scientists, players, and the families of athletes who have literally given everything to the game. It's fourth and inches. Can football save itself again?

    Most of the people who live near tapir habitat in Brazil’s vast Pantanal (“the Everglades on steroids”) haven’t seen the elusive snorkel-snouted mammal, either. In this arresting nonfiction picture book, Sibert winners Sy Montgomery and Nic Bishop join a tapir-finding expedition led by the Brazilian field scientist Pati Medici. Aspiring scientists will love the immediate, often humorous “you are there” descriptions of fieldwork, and gadget lovers will revel in the high-tech science at play, from microchips to the camera traps that capture the “soap opera” of tapir life.

    From the world’s most painful hornet, to the flies that transmit deadly diseases, to millipedes that stop traffic, to the “bookworms” that devour libraries, to the Japanese beetles munching on your roses, Wicked Bugs delves into the extraordinary powers of many-legged creatures. With wit, style, and exacting research, Stewart has uncovered the most terrifying and titillating stories of bugs gone wild. It’s an A to Z of insect enemies, interspersed with sections that explore bugs with kinky sex lives (“She’s Just Not That Into You”), creatures lurking in the cupboard (“Fear No Weevil”), insects eating your tomatoes (“Gardener’s Dirty Dozen”), and phobias that feed our (sometimes) irrational responses to bugs (“Have No Fear”). Intricate and strangely beautiful etchings and drawings by Briony Morrow-Cribbs capture diabolical bugs of all shapes and sizes in this mixture of history, science, murder, and intrigue that begins—but doesn’t end—in your own backyard.

    Some of these drugs are truly transformative, offering major improvements in how long patients live or how they feel--but what is often missing from the popular narrative is that, far too often, these new drugs have marginal or minimal benefits. Some are even harmful. In Malignant, hematologist-oncologist Dr. Vinayak K. Prasad writes about the many sobering examples of how patients are too often failed by cancer policy and by how oncology is practiced. Throughout this work, Prasad illuminates deceptive practices which- promote novel cancer therapies long before credible data are available to support such treatment; and- exaggerate the potential benefits of new therapies, many of which cost thousands and in some cases hundreds of thousands of dollars.Prasad then critiques the financial conflicts of interest that pervade the oncology field, the pharmaceutical industry, and the US Food and Drug administration.This is a book about how the actions of human beings--our policies, our standards of evidence, and our drug regulation--incentivize the pursuit of marginal or unproven therapies at lofty and unsustainable prices. Prasad takes us through how cancer trials are conducted, how drugs come to market, and how pricing decisions are made, asking how we can ensure that more cancer drugs deliver both greater benefit and a lower price. Ultimately, Prasad says,- more cancer clinical trials should measure outcomes that actually matter to people with cancer;- patients on those trials should look more like actual global citizens;- we need drug regulators to raise, not perpetually lower, the bar for approval; and- we need unbiased patient advocates and experts.This well-written, opinionated, and engaging book explains what we can do differently to make serious and sustained progress against cancer--and how we can avoid repeating the policy and practice mistakes of the past.

    As part of a plan to save money, government officials decided that Flint would temporarily switch its water supply from Lake Huron to the Flint River. Within months, many residents broke out in rashes. Then it got worse: children stopped growing. Some people were hospitalized with mysterious illnesses; others died. Citizens of Flint protested that the water was dangerous. Despite what seemed so apparent from the murky, foul-smelling liquid pouring from the city’s faucets, officials refused to listen. They treated the people of Flint as the problem, not the water, which was actually poisoning thousands.Through interviews with residents and intensive research into legal records and news accounts, journalist Candy J. Cooper, assisted by writer-editor Marc Aronson, reveals the true story of Flint. Poisoned Water shows not just how the crisis unfolded in 2014, but also the history of racism and segregation that led up to it, the beliefs and attitudes that fueled it, and how the people of Flint fought—and are still fighting—for clean water and healthy lives.