Book picks similar to
Biological Sequence Analysis: Probabilistic Models of Proteins and Nucleic Acids by Richard Durbin
biology
science
bioinformatics
reference
An Introduction to Statistical Learning: With Applications in R
Gareth James - 2013
This book presents some of the most important modeling and prediction techniques, along with relevant applications. Topics include linear regression, classification, resampling methods, shrinkage approaches, tree- based methods, support vector machines, clustering, and more. Color graphics and real-world examples are used to illustrate the methods presented. Since the goal of this textbook is to facilitate the use of these statistical learning techniques by practitioners in science, industry, and other fields, each chapter contains a tutorial on implementing the analyses and methods presented in R, an extremely popular open source statistical software platform. Two of the authors co-wrote The Elements of Statistical Learning (Hastie, Tibshirani and Friedman, 2nd edition 2009), a popular reference book for statistics and machine learning researchers. An Introduction to Statistical Learning covers many of the same topics, but at a level accessible to a much broader audience. This book is targeted at statisticians and non-statisticians alike who wish to use cutting-edge statistical learning techniques to analyze their data. The text assumes only a previous course in linear regression and no knowledge of matrix algebra.
Quantum Computing Since Democritus
Scott Aaronson - 2013
Full of insights, arguments and philosophical perspectives, the book covers an amazing array of topics. Beginning in antiquity with Democritus, it progresses through logic and set theory, computability and complexity theory, quantum computing, cryptography, the information content of quantum states and the interpretation of quantum mechanics. There are also extended discussions about time travel, Newcomb's Paradox, the anthropic principle and the views of Roger Penrose. Aaronson's informal style makes this fascinating book accessible to readers with scientific backgrounds, as well as students and researchers working in physics, computer science, mathematics and philosophy.
Hands-On Machine Learning with Scikit-Learn and TensorFlow
Aurélien Géron - 2017
Now that machine learning is thriving, even programmers who know close to nothing about this technology can use simple, efficient tools to implement programs capable of learning from data. This practical book shows you how.By using concrete examples, minimal theory, and two production-ready Python frameworks—Scikit-Learn and TensorFlow—author Aurélien Géron helps you gain an intuitive understanding of the concepts and tools for building intelligent systems. You’ll learn how to use a range of techniques, starting with simple Linear Regression and progressing to Deep Neural Networks. If you have some programming experience and you’re ready to code a machine learning project, this guide is for you.This hands-on book shows you how to use:Scikit-Learn, an accessible framework that implements many algorithms efficiently and serves as a great machine learning entry pointTensorFlow, a more complex library for distributed numerical computation, ideal for training and running very large neural networksPractical code examples that you can apply without learning excessive machine learning theory or algorithm details
Deep Learning
Ian Goodfellow - 2016
Because the computer gathers knowledge from experience, there is no need for a human computer operator to formally specify all the knowledge that the computer needs. The hierarchy of concepts allows the computer to learn complicated concepts by building them out of simpler ones; a graph of these hierarchies would be many layers deep. This book introduces a broad range of topics in deep learning.The text offers mathematical and conceptual background, covering relevant concepts in linear algebra, probability theory and information theory, numerical computation, and machine learning. It describes deep learning techniques used by practitioners in industry, including deep feedforward networks, regularization, optimization algorithms, convolutional networks, sequence modeling, and practical methodology; and it surveys such applications as natural language processing, speech recognition, computer vision, online recommendation systems, bioinformatics, and videogames. Finally, the book offers research perspectives, covering such theoretical topics as linear factor models, autoencoders, representation learning, structured probabilistic models, Monte Carlo methods, the partition function, approximate inference, and deep generative models.Deep Learning can be used by undergraduate or graduate students planning careers in either industry or research, and by software engineers who want to begin using deep learning in their products or platforms. A website offers supplementary material for both readers and instructors.
Artificial Intelligence: A Modern Approach
Stuart Russell - 1994
The long-anticipated revision of this best-selling text offers the most comprehensive, up-to-date introduction to the theory and practice of artificial intelligence. *NEW-Nontechnical learning material-Accompanies each part of the book. *NEW-The Internet as a sample application for intelligent systems-Added in several places including logical agents, planning, and natural language. *NEW-Increased coverage of material - Includes expanded coverage of: default reasoning and truth maintenance systems, including multi-agent/distributed AI and game theory; probabilistic approaches to learning including EM; more detailed descriptions of probabilistic inference algorithms. *NEW-Updated and expanded exercises-75% of the exercises are revised, with 100 new exercises. *NEW-On-line Java software. *Makes it easy for students to do projects on the web using intelligent agents. *A unified, agent-based approach to AI-Organizes the material around the task of building intelligent agents. *Comprehensive, up-to-date coverage-Includes a unified view of the field organized around the rational decision making pa
The Algorithm Design Manual
Steven S. Skiena - 1997
Drawing heavily on the author's own real-world experiences, the book stresses design and analysis. Coverage is divided into two parts, the first being a general guide to techniques for the design and analysis of computer algorithms. The second is a reference section, which includes a catalog of the 75 most important algorithmic problems. By browsing this catalog, readers can quickly identify what the problem they have encountered is called, what is known about it, and how they should proceed if they need to solve it. This book is ideal for the working professional who uses algorithms on a daily basis and has need for a handy reference. This work can also readily be used in an upper-division course or as a student reference guide. THE ALGORITHM DESIGN MANUAL comes with a CD-ROM that contains: * a complete hypertext version of the full printed book. * the source code and URLs for all cited implementations. * over 30 hours of audio lectures on the design and analysis of algorithms are provided, all keyed to on-line lecture notes.
Human Molecular Genetics
Tom Strachan - 1996
While maintaining the hallmark features of previous editions, the Fourth Edition has been completely updated. It includes new Key Concepts at the beginning of each chapter and annotated further reading at the conclusion of each chapter, to help readers navigate the wealth of information in this subject.The text has been restructured so genomic technologies are integrated throughout, and next generation sequencing is included. Genetic testing, screening, approaches to therapy, personalized medicine, and disease models have been brought together in one section. Coverage of cell biology including stem cells and cell therapy, studying gene function and structure, comparative genomics, model organisms, noncoding RNAs and their functions, and epigenetics have all been expanded.
Algorithms
Robert Sedgewick - 1983
This book surveys the most important computer algorithms currently in use and provides a full treatment of data structures and algorithms for sorting, searching, graph processing, and string processing -- including fifty algorithms every programmer should know. In this edition, new Java implementations are written in an accessible modular programming style, where all of the code is exposed to the reader and ready to use.The algorithms in this book represent a body of knowledge developed over the last 50 years that has become indispensable, not just for professional programmers and computer science students but for any student with interests in science, mathematics, and engineering, not to mention students who use computation in the liberal arts.The companion web site, algs4.cs.princeton.edu contains An online synopsis Full Java implementations Test data Exercises and answers Dynamic visualizations Lecture slides Programming assignments with checklists Links to related material The MOOC related to this book is accessible via the "Online Course" link at algs4.cs.princeton.edu. The course offers more than 100 video lecture segments that are integrated with the text, extensive online assessments, and the large-scale discussion forums that have proven so valuable. Offered each fall and spring, this course regularly attracts tens of thousands of registrants.Robert Sedgewick and Kevin Wayne are developing a modern approach to disseminating knowledge that fully embraces technology, enabling people all around the world to discover new ways of learning and teaching. By integrating their textbook, online content, and MOOC, all at the state of the art, they have built a unique resource that greatly expands the breadth and depth of the educational experience.
From Mathematics to Generic Programming
Alexander A. Stepanov - 2014
If you're a reasonably proficient programmer who can think logically, you have all the background you'll need. Stepanov and Rose introduce the relevant abstract algebra and number theory with exceptional clarity. They carefully explain the problems mathematicians first needed to solve, and then show how these mathematical solutions translate to generic programming and the creation of more effective and elegant code. To demonstrate the crucial role these mathematical principles play in many modern applications, the authors show how to use these results and generalized algorithms to implement a real-world public-key cryptosystem. As you read this book, you'll master the thought processes necessary for effective programming and learn how to generalize narrowly conceived algorithms to widen their usefulness without losing efficiency. You'll also gain deep insight into the value of mathematics to programming--insight that will prove invaluable no matter what programming languages and paradigms you use. You will learn aboutHow to generalize a four thousand-year-old algorithm, demonstrating indispensable lessons about clarity and efficiencyAncient paradoxes, beautiful theorems, and the productive tension between continuous and discreteA simple algorithm for finding greatest common divisor (GCD) and modern abstractions that build on itPowerful mathematical approaches to abstractionHow abstract algebra provides the idea at the heart of generic programmingAxioms, proofs, theories, and models: using mathematical techniques to organize knowledge about your algorithms and data structuresSurprising subtleties of simple programming tasks and what you can learn from themHow practical implementations can exploit theoretical knowledge
Physical Chemistry
Ira N. Levine - 1978
In this title, the treatment is made easy-to-follow by giving step-by-step derivations, explanations and by avoiding advanced mathematics unfamiliar to students. It covers: math and physics thorough review sections; and worked examples, followed by a practice exercise.
The Art of Electronics
Paul Horowitz - 1980
Widely accepted as the authoritative text and reference on electronic circuit design, both analog and digital, this book revolutionized the teaching of electronics by emphasizing the methods actually used by circuit designers -- a combination of some basic laws, rules of thumb, and a large bag of tricks. The result is a largely nonmathematical treatment that encourages circuit intuition, brainstorming, and simplified calculations of circuit values and performance. The new Art of Electronics retains the feeling of informality and easy access that helped make the first edition so successful and popular. It is an ideal first textbook on electronics for scientists and engineers and an indispensable reference for anyone, professional or amateur, who works with electronic circuits.
An Introduction to Systems Biology: Design Principles of Biological Circuits
Uri Alon - 2006
It provides a simple mathematical framework which can be used to understand and even design biological circuits. The textavoids specialist terms, focusing instead on several well-studied biological systems that concisely demonstrate key principles. An Introduction to Systems Biology: Design Principles of Biological Circuits builds a solid foundation for the intuitive understanding of general principles. It encourages the reader to ask why a system is designed in a particular way and then proceeds to answer with simplified models.
The Elements of Statistical Learning: Data Mining, Inference, and Prediction
Trevor Hastie - 2001
With it has come vast amounts of data in a variety of fields such as medicine, biology, finance, and marketing. The challenge of understanding these data has led to the development of new tools in the field of statistics, and spawned new areas such as data mining, machine learning, and bioinformatics. Many of these tools have common underpinnings but are often expressed with different terminology. This book describes the important ideas in these areas in a common conceptual framework. While the approach is statistical, the emphasis is on concepts rather than mathematics. Many examples are given, with a liberal use of color graphics. It should be a valuable resource for statisticians and anyone interested in data mining in science or industry. The book's coverage is broad, from supervised learning (prediction) to unsupervised learning. The many topics include neural networks, support vector machines, classification trees and boosting—the first comprehensive treatment of this topic in any book. Trevor Hastie, Robert Tibshirani, and Jerome Friedman are professors of statistics at Stanford University. They are prominent researchers in this area: Hastie and Tibshirani developed generalized additive models and wrote a popular book of that title. Hastie wrote much of the statistical modeling software in S-PLUS and invented principal curves and surfaces. Tibshirani proposed the Lasso and is co-author of the very successful An Introduction to the Bootstrap. Friedman is the co-inventor of many data-mining tools including CART, MARS, and projection pursuit.
Data Science from Scratch: First Principles with Python
Joel Grus - 2015
In this book, you’ll learn how many of the most fundamental data science tools and algorithms work by implementing them from scratch.
If you have an aptitude for mathematics and some programming skills, author Joel Grus will help you get comfortable with the math and statistics at the core of data science, and with hacking skills you need to get started as a data scientist. Today’s messy glut of data holds answers to questions no one’s even thought to ask. This book provides you with the know-how to dig those answers out.
Get a crash course in Python
Learn the basics of linear algebra, statistics, and probability—and understand how and when they're used in data science
Collect, explore, clean, munge, and manipulate data
Dive into the fundamentals of machine learning
Implement models such as k-nearest Neighbors, Naive Bayes, linear and logistic regression, decision trees, neural networks, and clustering
Explore recommender systems, natural language processing, network analysis, MapReduce, and databases