Uncle Tungsten


Oliver Sacks - 2001
    He tells of the large science-steeped family who fostered his early fascination with chemistry. There follow his years at boarding school where, though unhappy, he developed the intellectual curiosity that would shape his later life. And we hear of his return to London, an emotionally bereft ten-year-old who found solace in his passion for learning. Uncle Tungsten radiates all the delight and wonder of a boy’s adventures, and is an unforgettable portrait of an extraordinary young mind.

Seeing Further: Ideas, Endeavours, Discoveries and Disputes — The Story of Science Through 350 Years of the Royal Society


Bill BrysonJohn D. Barrow - 2010
    A twenty-eight year old — and not widely famous — Christopher Wren was giving a lecture on astronomy. As his audience listened to him speak, they decided that it would be a good idea to create a Society to promote the accumulation of useful knowledge.With that, the Royal Society was born. Since its birth, the Royal Society has pioneered scientific exploration and discovery. Isaac Newton, Charles Darwin, Albert Einstein, Robert Hooke, Robert Boyle, Joseph Banks, Humphry Davy, Isambard Kingdom Brunel, John Locke, Alexander Fleming — all were fellows.Bill Bryson’s favourite fellow was Reverend Thomas Bayes, a brilliant mathematician who devised Bayes’ theorem. Its complexity meant that it had little practical use in Bayes’ own lifetime, but today his theorem is used for weather forecasting, astrophysics and stock market analysis. A milestone in mathematical history, it only exists because the Royal Society decided to preserve it — just in case. The Royal Society continues to do today what it set out to do all those years ago. Its members have split the atom, discovered the double helix, the electron, the computer and the World Wide Web. Truly international in its outlook, it has created modern science.Seeing Further celebrates its momentous history and achievements, bringing together the very best of science writing. Filled with illustrations of treasures from the Society’s archives, this is a unique, ground-breaking and beautiful volume, and a suitable reflection of the immense achievements of science.

The Tale of the Dueling Neurosurgeons: The History of the Human Brain as Revealed by True Stories of Trauma, Madness, and Recovery


Sam Kean - 2014
     Early studies of the functions of the human brain used a simple method: wait for misfortune to strike-strokes, seizures, infectious diseases, lobotomies, horrendous accidents-and see how the victim coped. In many cases survival was miraculous, and observers could only marvel at the transformations that took place afterward, altering victims' personalities. An injury to one section can leave a person unable to recognize loved ones; some brain trauma can even make you a pathological gambler, pedophile, or liar. But a few scientists realized that these injuries were an opportunity for studying brain function at its extremes. With lucid explanations and incisive wit, Sam Kean explains the brain's secret passageways while recounting forgotten stories of common people whose struggles, resiliency, and deep humanity made modern neuroscience possible.

Patient H.M.: A Story of Memory, Madness, and Family Secrets


Luke Dittrich - 2016
    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

The Poisoner's Handbook: Murder and the Birth of Forensic Medicine in Jazz Age New York


Deborah Blum - 2010
    In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

Quantum: Einstein, Bohr and the Great Debate About the Nature of Reality


Manjit Kumar - 2007
    And yet for many years it was equally baffling for scientists themselves. Manjit Kumar gives a dramatic and superbly-written history of this fundamental scientific revolution, and the divisive debate at its heart.For 60 years most physicists believed that quantum theory denied the very existence of reality itself. Yet Kumar shows how the golden age of physics ignited the greatest intellectual debate of the twentieth century.Quantum sets the science in the context of the great upheavals of the modern age. In 1925 the quantum pioneers nearly all hailed from upper-middle-class academic families; most were German; and their average age was 24. But it was their irrational, romantic spirit, formed in reaction to the mechanised slaughter of the First World War that inspired their will to test science to its limits.The essential read for anyone fascinated by this complex and thrilling story and by the band of young men at its heart.

Brilliant Blunders: From Darwin to Einstein - Colossal Mistakes by Great Scientists That Changed Our Understanding of Life and the Universe


Mario Livio - 2013
    Nobody is perfect. And that includes five of the greatest scientists in history—Charles Darwin, William Thomson (Lord Kelvin), Linus Pauling, Fred Hoyle, and Albert Einstein. But the mistakes that these great luminaries made helped advance science. Indeed, as Mario Livio explains, science thrives on error, advancing when erroneous ideas are disproven.As a young scientist, Einstein tried to conceive of a way to describe the evolution of the universe at large, based on General Relativity—his theory of space, time, and gravity. Unfortunately he fell victim to a misguided notion of aesthetic simplicity. Fred Hoyle was an eminent astrophysicist who ridiculed an emerging theory about the origin of the universe that he dismissively called “The Big Bang.” The name stuck, but Hoyle was dead wrong in his opposition.They, along with Darwin (a blunder in his theory of Natural Selection), Kelvin (a blunder in his calculation of the age of the earth), and Pauling (a blunder in his model for the structure of the DNA molecule), were brilliant men and fascinating human beings. Their blunders were a necessary part of the scientific process. Collectively they helped to dramatically further our knowledge of the evolution of life, the Earth, and the universe.

The Emperor's New Mind: Concerning Computers, Minds and the Laws of Physics


Roger Penrose - 1989
    Admittedly, computers now play chess at the grandmaster level, but do they understand the game as we do? Can a computer eventually do everything a human mind can do? In this absorbing and frequently contentious book, Roger Penrose--eminent physicist and winner, with Stephen Hawking, of the prestigious Wolf prize--puts forward his view that there are some facets of human thinking that can never be emulated by a machine. Penrose examines what physics and mathematics can tell us about how the mind works, what they can't, and what we need to know to understand the physical processes of consciousness. He is among a growing number of physicists who think Einstein wasn't being stubborn when he said his little finger told him that quantum mechanics is incomplete, and he concludes that laws even deeper than quantum mechanics are essential for the operation of a mind. To support this contention, Penrose takes the reader on a dazzling tour that covers such topics as complex numbers, Turing machines, complexity theory, quantum mechanics, formal systems, Godel undecidability, phase spaces, Hilbert spaces, black holes, white holes, Hawking radiation, entropy, quasicrystals, the structure of the brain, and scores of other subjects. The Emperor's New Mind will appeal to anyone with a serious interest in modern physics and its relation to philosophical issues, as well as to physicists, mathematicians, philosophers and those on either side of the AI debate.

Pandora's Lab: Seven Stories of Science Gone Wrong


Paul A. Offit - 2017
    These are today's sins of science—as deplorable as mistaken past ideas about advocating racial purity or using lobotomies as a cure for mental illness. These unwitting errors add up to seven lessons both cautionary and profound, narrated by renowned author and speaker Paul A. Offit. Offit uses these lessons to investigate how we can separate good science from bad, using some of today's most controversial creations—e-cigarettes, GMOs, drug treatments for ADHD—as case studies. For every "Aha!" moment that should have been an "Oh no," this book is an engrossing account of how science has been misused disastrously—and how we can learn to use its power for good.

The Brain: The Story of You


David Eagleman - 2015
    Join renowned neuroscientist David Eagleman for a journey into the questions at the mysterious heart of our existence. What is reality? Who are “you”? How do you make decisions? Why does your brain need other people? How is technology poised to change what it means to be human?  In the course of his investigations, Eagleman guides us through the world of extreme sports, criminal justice, facial expressions, genocide, brain surgery, gut feelings, robotics, and the search for immortality.  Strap in for a whistle-stop tour into the inner cosmos. In the infinitely dense tangle of billions of brain cells and their trillions of connections, something emerges that you might not have expected to see in there: you.

The Emperor of All Maladies: A Biography of Cancer


Siddhartha Mukherjee - 2010
    Physician, researcher, and award-winning science writer, Siddhartha Mukherjee examines cancer with a cellular biologist’s precision, a historian’s perspective, and a biographer’s passion. The result is an astonishingly lucid and eloquent chronicle of a disease humans have lived with - and perished from - for more than five thousand years. The story of cancer is a story of human ingenuity, resilience, and perseverance, but also of hubris, paternalism, and misperception. Mukherjee recounts centuries of discoveries, setbacks, victories, and deaths, told through the eyes of his predecessors and peers, training their wits against an infinitely resourceful adversary that, just three decades ago, was thought to be easily vanquished in an all-out “war against cancer.” The book reads like a literary thriller with cancer as the protagonist. From the Persian Queen Atossa, whose Greek slave cut off her malignant breast, to the nineteenth-century recipients of primitive radiation and chemotherapy to Mukherjee’s own leukemia patient, Carla, The Emperor of All Maladies is about the people who have soldiered through fiercely demanding regimens in order to survive—and to increase our understanding of this iconic disease. Riveting, urgent, and surprising, The Emperor of All Maladies provides a fascinating glimpse into the future of cancer treatments. It is an illuminating book that provides hope and clarity to those seeking to demystify cancer.

The Great Influenza: The Story of the Deadliest Pandemic in History


John M. Barry - 2004
    It killed more people in twenty-four months than AIDS killed in twenty-four years, more in a year than the Black Death killed in a century. But this was not the Middle Ages, and 1918 marked the first collision of science and epidemic disease. Magisterial in its breadth of perspective and depth of research and now revised to reflect the growing danger of the avian flu, The Great Influenza is ultimately a tale of triumph amid tragedy, which provides us with a precise and sobering model as we confront the epidemics looming on our own horizon. John M. Barry has written a new afterword for this edition that brings us up to speed on the terrible threat of the avian flu and suggest ways in which we might head off another flu pandemic.

Gut Feelings: The Intelligence of the Unconscious


Gerd Gigerenzer - 2007
    Gladwell showed us how snap decisions often yield better results than careful analysis. Now, Gigerenzer explains why our intuition is such a powerful decision-making tool. Drawing on a decade of research at the Max Plank Institute, Gigerenzer demonstrates that our gut feelings are actually the result of unconscious mental processes—processes that apply rules of thumb that we’ve derived from our environment and prior experiences. The value of these unconscious rules lies precisely in their difference from rational analysis—they take into account only the most useful bits of information rather than attempting to evaluate all possible factors. By examining various decisions we make—how we choose a spouse, a stock, a medical procedure, or the answer to a million-dollar game show question—Gigerenzer shows how gut feelings not only lead to good practical decisions, but also underlie the moral choices that make our society function. In the tradition of Blink and Freakonomics, Gut Feelings is an exploration of the myriad influences and factors (nature and nurture) that affect how the mind works, grounded in cutting-edge research and conveyed through compelling real-life examples.

The Lab Rat Chronicles: A Neuroscientist Reveals Life Lessons from the Planet's Most Successful Mammals


Kelly Lambert - 2011
    Her twenty- five-year career conducting experiments that involve rats has led her to a surprising conclusion: Through their adaptive strategies and good habits, these unassuming little animals can teach us some essential lessons about how we, as humans, can lead successful lives. From emotional resilience and a strong work ethic to effective parenting and staying healthy, the lab rat is an unlikely but powerful role model for us all. This is a surprising and engaging guided tour into the sophisticated mental, emotional, and behavioral worlds of these frequently maligned and often misunderstood little creatures.

Homo Deus: A History of Tomorrow


Yuval Noah Harari - 2015
    This may seem hard to accept, but, as Harari explains in his trademark style—thorough, yet riveting—famine, plague and war have been transformed from incomprehensible and uncontrollable forces of nature into manageable challenges. For the first time ever, more people die from eating too much than from eating too little; more people die from old age than from infectious diseases; and more people commit suicide than are killed by soldiers, terrorists and criminals put together. The average American is a thousand times more likely to die from binging at McDonalds than from being blown up by Al Qaeda.What then will replace famine, plague, and war at the top of the human agenda? As the self-made gods of planet earth, what destinies will we set ourselves, and which quests will we undertake? Homo Deus explores the projects, dreams and nightmares that will shape the twenty-first century—from overcoming death to creating artificial life. It asks the fundamental questions: Where do we go from here? And how will we protect this fragile world from our own destructive powers? This is the next stage of evolution. This is Homo Deus.With the same insight and clarity that made Sapiens an international hit and a New York Times bestseller, Harari maps out our future.