As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    In the past two decades, deaths of despair from suicide, drug overdose, and alcoholism have risen dramatically, and now claim hundreds of thousands of American lives each year--and they're still rising. Anne Case and Angus Deaton, known for first sounding the alarm about deaths of despair, explain the overwhelming surge in these deaths and shed light on the social and economic forces that are making life harder for the working class. They demonstrate why, for those who used to prosper in America, capitalism is no longer delivering.Deaths of Despair and the Future of Capitalism paints a troubling portrait of the American dream in decline. For the white working class, today's America has become a land of broken families and few prospects. As the college educated become healthier and wealthier, adults without a degree are literally dying from pain and despair. In this critically important book, Case and Deaton tie the crisis to the weakening position of labor, the growing power of corporations, and, above all, to a rapacious health-care sector that redistributes working-class wages into the pockets of the wealthy. Capitalism, which over two centuries lifted countless people out of poverty, is now destroying the lives of blue-collar America.This book charts a way forward, providing solutions that can rein in capitalism's excesses and make it work for everyone.

    In this ground-breaking investigation, Laura Bates traces the roots of misogyny across a complex spider's web of groups extending from Men's Rights Activists and Pick up Artists to "Men Going their Own Way" trolls and the Incel movement, in the name of which some men have committed terrorist acts. Drawing parallels with other extremist movements around the world, Bates seeks to understand what attracts men to the movement, how it grooms and radicalizes boys, how it operates, and what can be done to stop it. Most urgently of all, she traces the pathways this extreme ideology has taken from the darkest corners of the internet to emerge covertly in our mainstream media, our playgrounds, and our parliament. Going undercover online and off, Bates provides the first, comprehensive look at this hitherto under-the-radar phenomenon, including fascinating interviews with trolls, former incels, the academics studying this movement, and the men fighting back.

    As recently as 2013, Tim Berners-Lee, often credited as the inventor of the World Wide Web, declared that “piece by piece, website by website, China’s ‘great firewall’ would meet the same fate as the Berlin Wall.” Yet these predictions have been proved wrong. In We Have Been Harmonized, award-winning journalist Kai Strittmatter reveals how the internet and high tech have transformed the power of Chinese authoritarians, allowing them to create the most horrifying surveillance state in history.Advances in technology—facial recognition, GPS tracking, supercomputer databases, mobile phones, high-resolution security cameras—make it nearly impossible for a Chinese citizen to hide anything from authorities. Text messages and emails are instantly stripped of “problematic” words. The year 1989—when the world witnessed the student protests and tragic massacre at Tiananmen Square—has been banished from search results. Cameras scan for “appropriate” facial expressions as they track individuals’ movements. Each citizen is given a score for good behavior. Those who lose points can be banned from traveling, have their internet speed reduced, or even have their toilet paper limited. All of this has happened with the help of Chinese tech companies, as well as the complicity of Western governments and corporations eager to gain access to China’s huge market. While these companies export their technology to authoritarian states around the globe, they are also reshaping American lives via app, smart phones, and computing. Strittmatter’s book is a terrifying portrait of an Orwellian nightmare unlike anything we’ve ever witnessed, and a dire warning about what could happen anywhere.

    Along the way, she meets biologists who are trying to preserve the world's rarest fish, which lives in a single tiny pool in the middle of the Mojave; engineers who are turning carbon emissions to stone in Iceland; Australian researchers who are trying to develop a super coral that can survive on a hotter globe; and physicists who are contemplating shooting tiny diamonds into the stratosphere to cool the earth.One way to look at human civilization, says Kolbert, is as a ten-thousand-year exercise in defying nature. In The Sixth Extinction, she explored the ways in which our capacity for destruction has reshaped the natural world. Now she examines how the very sorts of interventions that have imperiled our planet are increasingly seen as the only hope for its salvation.

    Kids typically no longer expect their lives to be better than their parents’ were. Dystopian scenarios loom ever larger in public consciousness as fisheries collapse, CO2 levels rise, and clouds of radioactive steam billow from “fail-safe” nuclear plants that failed. Despite the technological marvels of our age—or perhaps because of them—these are dark days.As comedian Louis C.K. put it, “Everything’s amazing, but nobody’s happy.”Even for the most fortunate among us, material abundance comes at a very high price. Facebook is a hollow replacement for face time. We produce more food than ever, but hunger and malnutrition are standard in most of the world while the rest of us stuff ourselves quite literally to death. Despair darkens ever more lives as rates of clinical depression and suicide continue their grim climb in the developed world. A third of all American children are obese or seriously overweight, and fifty four million of us are pre-diabetic. Pre-schoolers represent the fastest-growing market for anti-depressants, while the rate of increase of depression among children is over twenty percent, according to a recent Harvard study. Twenty four million American adults are thought to suffer from Post-Traumatic Stress Disorder—mostly attributable to the never-ending wars that have become part of modern life for the swelling underclass with few other employment opportunities.It’s common to wonder how an anthropologist from Mars would view our world or what sage advice an emissary from the future would bring back. But how would a time-traveler from our prehistoric past assess the lives we lead and the future prospects for the path we’re on? Such a visitor from 200 centuries ago would no doubt be impressed by much of what she found here. But once her amazement at iPhones, air travel, and liver transplants subsided, what would she make of our daily lives? Would she ultimately be more impressed by our advances or dismayed by what we’ve lost in our always accelerating rush toward the future?With faith in the future melting like an overheated glacier even as contentment with the present evaporates, it’s high time for a sober reassessment of the past. Ten thousand years since turning from the ancient path our ancestors trod forever, it’s time for a scientifically-informed, multidisciplinary look at the effects of this fateful divergence. It’s time to ask what may be the most subversive question of all: Are modern humans, even the most fortunate among us, living significantly better lives than our pre-civilized ancestors? Taken as a whole, is civilization a net gain for individual human beings?

    This pervasive yet little examined obsession is arguably the most powerful and devastating market force of our time-the engine of globalization, outsourcing, planned obsolescence, and economic instability in an increasingly unsettled world. Low price is so alluring that we may have forgotten how thoroughly we once distrusted it. Ellen Ruppel Shell traces the birth of the bargain as we know it from the Industrial Revolution to the assembly line and beyond, homing in on a number of colorful characters, such as Gene Verkauf (his name is Yiddish for "to sell"), founder of E. J. Korvette, the discount chain that helped wean customers off traditional notions of value. The rise of the chain store in post-Depression America led to the extolling of convenience over quality, and big-box retailers completed the reeducation of the American consumer by making them prize low price in the way they once prized durability and craftsmanship. The effects of this insidious perceptual shift are vast: a blighted landscape, escalating debt (both personal and national), stagnating incomes, fraying communities, and a host of other socioeconomic ills. That's a long list of charges, and it runs counter to orthodox economics which argues that low price powers productivity by stimulating a brisk free market. But Shell marshals evidence from a wide range of fields-history, sociology, marketing, psychology, even economics itself-to upend the conventional wisdom. Cheap also unveils the fascinating and unsettling illogic that underpins our bargain-hunting reflex and explains how our deep-rooted need for bargains colors every aspect of our psyches and social lives. In this myth-shattering, closely reasoned, and exhaustively reported investigation, Shell exposes the astronomically high cost of cheap.

    Decluttering. A parent's death. Sooner or later, all of us are faced with things we no longer need or want. But when we drop our old clothes and other items off at a local donation center, where do they go? Sometimes across the country-or even halfway across the world-to people and places who find value in what we leave behind.In Secondhand, journalist Adam Minter takes us on an unexpected adventure into the often-hidden, multibillion-dollar industry of reuse: thrift stores in the American Southwest to vintage shops in Tokyo, flea markets in Southeast Asia to used-goods enterprises in Ghana, and more. Along the way, Minter meets the fascinating people who handle-and profit from-our rising tide of discarded stuff, and asks a pressing question: In a world that craves shiny and new, is there room for it all?Secondhand offers hopeful answers and hard truths. A history of the stuff we've used and a contemplation of why we keep buying more, it also reveals the marketing practices, design failures, and racial prejudices that push used items into landfills instead of new homes. Secondhand shows us that it doesn't have to be this way, and what really needs to change to build a sustainable future free of excess stuff.

    The Sovereign Individual details strategies necessary for adapting financially to the next phase of Western civilization. Few observers of the late twentieth century have their fingers so presciently on the pulse of the global political and economic realignment ushering in the new millennium as do James Dale Davidson and Lord William Rees-Mogg. Their bold prediction of disaster on Wall Street in Blood in the Streets was borne out by Black Tuesday. In their ensuing bestseller, The Great Reckoning, published just weeks before the coup attempt against Gorbachev, they analyzed the pending collapse of the Soviet Union and foretold the civil war in Yugoslavia and other events that have proved to be among the most searing developments of the past few years. In The Sovereign Individual, Davidson and Rees-Mogg explore the greatest economic and political transition in centuries—the shift from an industrial to an information-based society. This transition, which they have termed "the fourth stage of human society," will liberate individuals as never before, irrevocably altering the power of government. This outstanding book will replace false hopes and fictions with new understanding and clarified values.

    Gilder says or writes is ever delivered at anything less than the fullest philosophical decibel... Mr. Gilder sounds less like a tech guru than a poet, and his words tumble out in a romantic cascade." “Google’s algorithms assume the world’s future is nothing more than the next moment in a random process. George Gilder shows how deep this assumption goes, what motivates people to make it, and why it’s wrong: the future depends on human action.” — Peter Thiel, founder of PayPal and Palantir Technologies and author of Zero to One: Notes on Startups, or How to Build the Future The Age of Google, built on big data and machine intelligence, has been an awesome era. But it’s coming to an end. In Life after Google, George Gilder—the peerless visionary of technology and culture—explains why Silicon Valley is suffering a nervous breakdown and what to expect as the post-Google age dawns. Google’s astonishing ability to “search and sort” attracts the entire world to its search engine and countless other goodies—videos, maps, email, calendars….And everything it offers is free, or so it seems. Instead of paying directly, users submit to advertising. The system of “aggregate and advertise” works—for a while—if you control an empire of data centers, but a market without prices strangles entrepreneurship and turns the Internet into a wasteland of ads. The crisis is not just economic. Even as advances in artificial intelligence induce delusions of omnipotence and transcendence, Silicon Valley has pretty much given up on security. The Internet firewalls supposedly protecting all those passwords and personal information have proved hopelessly permeable. The crisis cannot be solved within the current computer and network architecture. The future lies with the “cryptocosm”—the new architecture of the blockchain and its derivatives. Enabling cryptocurrencies such as bitcoin and ether, NEO and Hashgraph, it will provide the Internet a secure global payments system, ending the aggregate-and-advertise Age of Google. Silicon Valley, long dominated by a few giants, faces a “great unbundling,” which will disperse computer power and commerce and transform the economy and the Internet. Life after Google is almost here.   For fans of "Wealth and Poverty," "Knowledge and Power," and "The Scandal of Money."

    With a perspective that is scientific, investigative, and personal, Jennifer L. Eberhardt offers a reasoned look into the effects of implicit racial bias, ranging from the subtle to the dramatic. Racial bias can lead to disparities in education, employment, housing, and the criminal justice system--and then those very disparities further reinforce the problem. In Biased, Eberhardt reveals how even when we are not aware of bias and genuinely wish to treat all people equally, ingrained stereotypes infect our visual perception, attention, memory, and behavior.Eberhardt's extensive work as a consultant to law enforcement, as well as a researcher with unprecedented access to data, including footage from police officers' body-worn cameras, informs every aspect of her book and makes it much more than a work of social psychology. Her research occurs not just in the laboratory but in police departments, courtrooms, prisons, boardrooms, and on the street. Interviews are interwoven with memories and stories from Eberhardt's own life and family. She offers practical suggestions for reform, and takes the reader behind the scenes to police departments implementing her suggestions. Refusing to shy away from the tragic consequences of prejudice, Eberhardt addresses how racial bias is not the fault of, or restricted to, a few "bad apples" in police departments or other institutions. We can see evidence of bias at all levels of society in media, education, and business practices. In Biased, Eberhardt reminds us that racial bias is a human problem--one all people can play a role in solving.

    Each blockbuster has a secret history--of power, influence, dark broadcasters, and passionate cults that turn some new products into cultural phenomena. Even the most brilliant ideas wither in obscurity if they fail to connect with the right network, and the consumers that matter most aren't the early adopters, but rather their friends, followers, and imitators -- the audience of your audience.In his groundbreaking investigation, Atlantic senior editor Derek Thompson uncovers the hidden psychology of why we like what we like and reveals the economics of cultural markets that invisibly shape our lives. Shattering the sentimental myths of hit-making that dominate pop culture and business, Thompson shows quality is insufficient for success, nobody has "good taste," and some of the most popular products in history were one bad break away from utter failure. It may be a new world, but there are some enduring truths to what audiences and consumers want. People love a familiar surprise: a product that is bold, yet sneakily recognizable.Every business, every artist, every person looking to promote themselves and their work wants to know what makes some works so successful while others disappear. Hit Makers is a magical mystery tour through the last century of pop culture blockbusters and the most valuable currency of the twenty-first century--people's attention.From the dawn of impressionist art to the future of Facebook, from small Etsy designers to the origin of Star Wars, Derek Thompson leaves no pet rock unturned to tell the fascinating story of how culture happens and why things become popular.In Hit Makers, Derek Thompson investigates: - The secret link between ESPN's sticky programming and the The Weeknd's catchy choruses - Why Facebook is the world's most important modern newspaper - How advertising critics predicted Donald Trump - The 5th grader who accidentally launched "Rock Around the Clock," the biggest hit in rock and roll history - How Barack Obama and his speechwriters think of themselves as songwriters - How Disney conquered the world--but the future of hits belongs to savvy amateurs and individuals - The French collector who accidentally created the Impressionist canon - Quantitative evidence that the biggest music hits aren't always the best - Why almost all Hollywood blockbusters are sequels, reboots, and adaptations - Why one year--1991--is responsible for the way pop music sounds today - Why another year --1932--created the business model of film - How data scientists proved that "going viral" is a myth - How 19th century immigration patterns explain the most heard song in the Western Hemisphere

     For several years, Andrew Marantz, a New Yorker staff writer, has been embedded in two worlds. The first is the world of social-media entrepreneurs, who, acting out of naïvete and reckless ambition, upended all traditional means of receiving and transmitting information. The second is the world of the people he calls "the gate crashers"—the conspiracists, white supremacists, and nihilist trolls who have become experts at using social media to advance their corrosive agenda. Antisocial ranges broadly—from the first mass-printed books to the trending hashtags of the present; from secret gatherings of neo-Fascists to the White House press briefing room—and traces how the unthinkable becomes thinkable, and then how it becomes reality. Combining the keen narrative detail of Bill Buford's Among the Thugs and the sweep of George Packer's The Unwinding, Antisocial reveals how the boundaries between technology, media, and politics have been erased, resulting in a deeply broken informational landscape—the landscape in which we all now live. Marantz shows how alienated young people are led down the rabbit hole of online radicalization, and how fringe ideas spread—from anonymous corners of social media to cable TV to the President's Twitter feed. Marantz also sits with the creators of social media as they start to reckon with the forces they've unleashed. Will they be able to solve the communication crisis they helped bring about, or are their interventions too little too late?

    If your anxiety about global warming is dominated by fears of sea-level rise, you are barely scratching the surface of what terrors are possible. In California, wildfires now rage year-round, destroying thousands of homes. Across the US, "500-year" storms pummel communities month after month, and floods displace tens of millions annually.This is only a preview of the changes to come. And they are coming fast. Without a revolution in how billions of humans conduct their lives, parts of the Earth could become close to uninhabitable, and other parts horrifically inhospitable, as soon as the end of this century.In his travelogue of our near future, David Wallace-Wells brings into stark relief the climate troubles that await--food shortages, refugee emergencies, and other crises that will reshape the globe. But the world will be remade by warming in more profound ways as well, transforming our politics, our culture, our relationship to technology, and our sense of history. It will be all-encompassing, shaping and distorting nearly every aspect of human life as it is lived today.Like An Inconvenient Truth and Silent Spring before it, The Uninhabitable Earth is both a meditation on the devastation we have brought upon ourselves and an impassioned call to action. For just as the world was brought to the brink of catastrophe within the span of a lifetime, the responsibility to avoid it now belongs to a single generation.

    Today, they lead to Beijing.'When The Silk Roads was published in 2015, it became an instant classic. A major reassessment of world history, it compelled us to look at the past from a different perspective. The New Silk Roads brings this story up to date, addressing the present and future of a world that is changing dramatically.Following the Silk Roads eastwards, from Europe through to China, by way of Russia and the Middle East, The New Silk Roads provides a timely reminder that we live in a world that is profoundly interconnected. In an age of Brexit and Trump, the themes of isolation and fragmentation permeating the Western world stand in sharp contrast to events along the Silk Roads since 2015, where ties have been strengthened and mutual cooperation established.With brilliant insight, Peter Frankopan takes a fresh look at the network of relationships being formed along the length and breadth of the Silk Roads today, assessing the global reverberations of these continual shifts in the centre of power - all too often absent from headlines in the West. This important - and ultimately hopeful - book asks us to reassess who we are and where we are in the world, illuminating the themes on which all our lives and livelihood depend.