This easy-to-follow guide leads you step by step through every bioinformatics task that can be done over the Internet. Forget long equations, computer-geek gibberish, and installing bulky programs that slow down your computer. You'll be amazed at all the things you can accomplish just by logging on and following these trusty directions. You get the tools you need to:Analyze all types of sequences Use all types of databases Work with DNA and protein sequences Conduct similarity searches Build a multiple sequence alignment Edit and publish alignments Visualize protein 3-D structures Construct phylogenetic trees This up-to-date second edition includes newly created and popular databases and Internet programs as well as multiple new genomes. It provides tips for using servers and places to seek resources to find out about what's going on in the bioinformatics world. Bioinformatics For Dummies will show you how to get the most out of your PC and the right Web tools so you'll be searching databases and analyzing sequences like a pro!

    Dennett, whom Chet Raymo of The Boston Globe calls "one of the most provocative thinkers on the planet," focuses his unerringly logical mind on the theory of natural selection, showing how Darwin's great idea transforms and illuminates our traditional view of humanity's place in the universe. Dennett vividly describes the theory itself and then extends Darwin's vision with impeccable arguments to their often surprising conclusions, challenging the views of some of the most famous scientists of our day.

    After 3.8 billion years humankind is about to start evolving by new rules...From leading geopolitical expert and technology futurist Jamie Metzl comes a groundbreaking exploration of the many ways genetic-engineering is shaking the core foundations of our lives -- sex, war, love, and death.At the dawn of the genetics revolution, our DNA is becoming as readable, writable, and hackable as our information technology. But as humanity starts retooling our own genetic code, the choices we make today will be the difference between realizing breathtaking advances in human well-being and descending into a dangerous and potentially deadly genetic arms race.Enter the laboratories where scientists are turning science fiction into reality. Look towards a future where our deepest beliefs, morals, religions, and politics are challenged like never before and the very essence of what it means to be human is at play. When we can engineer our future children, massively extend our lifespans, build life from scratch, and recreate the plant and animal world, should we?

    Konrad Lorenz was gifted with a similar power of understanding the animal world. He was that rare beast, a brilliant scientist who could write (and indeed draw) beautifully. He did more than any other person to establish and popularize the study of how animals behave, receiving a Nobel Prize for his work. King Solomon's Ring, the book which brought him worldwide recognition, is a delightful treasury of observations and insights into the lives of all sorts of creatures, from jackdaws and water-shrews to dogs, cats and even wolves. Charmingly illustrated by Lorenz himself, this book is a wonderfully written introduction to the world of our furred and feathered friends, a world which often provides an uncanny resemblance to our own. A must for any animal-lover!

    Dr Carl Sagan takes us on a great reading adventure, offering his vivid and startling insights into the brains of humans & beasts, the origin of human intelligence, the function of our most haunting legends and their amazing links to recent discoveries.

    Includes letters and lectures by Huxley never published elsewhere. In May 1953 Aldous Huxley took four-tenths of a gram of mescaline. The mystical and transcendent experience that followed set him off on an exploration that was to produce a revolutionary body of work about the inner reaches of the human mind. Huxley was decades ahead of his time in his anticipation of the dangers modern culture was creating through explosive population increase, headlong technological advance, and militant nationalism, and he saw psychedelics as the greatest means at our disposal to "remind adults that the real world is very different from the misshapen universe they have created for themselves by means of their culture-conditioned prejudices." Much of Huxley's writings following his 1953 mescaline experiment can be seen as his attempt to reveal the power of these substances to awaken a sense of the sacred in people living in a technological society hostile to mystical revelations. Moksha, a Sanskrit word meaning "liberation," is a collection of the prophetic and visionary writings of Aldous Huxley. It includes selections from his acclaimed novels Brave New World and Island, both of which envision societies centered around the use of psychedelics as stabilizing forces, as well as pieces from The Doors of Perception and Heaven and Hell, his famous works on consciousness expansion.

    Wright unveils the genetic strategies behind everything from our sexual preferences to our office politics--as well as their implications for our moral codes and public policies. Illustrations.

     For his groundbreaking sexual research, Alfred Kinsey and his team interviewed 18,000 people, relying on them to honestly report their most intimate experiences. Using the Internet, the neuroscientists Ogas and Gaddam quietly observed the raw sexual behaviors of half a billion people. By combining their observations with neuroscience and animal research, these two young neuroscientists finally answer the long-disputed question: what do people really like? Ogas and Gaddam's findings are transforming the way scientists and therapists think about sexual desire. In their startling book, Ogas and Gaddam analyze a "billion wicked thoughts" on the Internet: a billion Web searches, a million individual search histories, a million erotic stories, a half-million erotic videos, a million Web sites, millions of online personal ads, and many other enormous sources of sexual data in order to understand the true differences between male and female desires, including: ?Men and women have hardwired sexual cues analogous to our hardwired tastes-there are sexual versions of sweet, sour, salty, savory, and bitter. But men and women are wired with different sets of cues. ?The male sexual brain resembles a reckless hunter, while the female sexual brain resembles a cautious detective agency. ?Men form their sexual interests during adolescence and rarely change. Women's sexual interests are plastic and change frequently. ?The male sexual brain is an "or gate": A single stimulus can arouse it. The female sexual brain is an "and gate": It requires many simultaneous stimuli to arouse it. ?When it comes to sexual arousal, men prefer overweight women to underweight women, and a significant number of men seek out erotic images of women in their 40s, 50s, and 60s. ?Women enjoy writing and sharing erotic stories with other women. The fastest growing genre of erotic stories for women are stories about two heterosexual men having sex. ?Though the male sexual brain is much more different from the female sexual brain than is commonly believed, the sexual brain of gay men is virtually identical to that of straight men. Featuring cutting-edge, jaw-dropping science, this wildly entertaining and controversial book helps readers understand their partner's sexual desires with a depth of knowledge unavailable from any other source. Its fascinating and occasionally disturbing findings will rock our modern understanding of sexuality, just as Kinsey's reports did sixty years ago.

    In What Is Life?, he takes up the challenge of describing what it means to be alive in a way that every reader can understand.It is a shared journey of discovery; step-by-step Nurse illuminates five great ideas that underpin biology—the Cell, the Gene, Evolution by Natural Selection, Life as Chemistry, and Life as Information. He introduces the scientists who made the most important advances, and, using his personal experiences in and out of the lab, he shares with us the challenges, the lucky breaks, and the thrilling eureka moments of discovery.Nurse writes with delight at life’s richness and with a sense of the urgent role of biology in our time. To survive the challenges that face us all today—climate change, pandemic, loss of biodiversity and food security—it is vital that we all understand what life is.

    It explains all this and much more. It discloses the best time to have a sex change, how to have a virgin birth, when to seduce your sisters or eat your lover. Quirky and brilliant, it takes as its starting point all creatures great and small worried about their bizarre sex lives, and the letters they write to the wise Dr Tatiana, the only agony aunt in all creation with a prodigious knowledge of both natural history and evolutionary biology.

    But as technology has advanced and our understanding of biology has deepened, the answer has evolved. For decades, scientists have been exploring the limits of nature by modifying and manipulating DNA, cells and whole organisms to create new ones that could never have existed on their own. In Creation, science writer Adam Rutherford explains how we are now radically exceeding the boundaries of evolution and engineering entirely novel creatures—from goats that produce spider silk in their milk to bacteria that excrete diesel to genetic circuits that identify and destroy cancer cells. As strange as some of these creations may sound, this new, synthetic biology is helping scientists develop radical solutions to some of the world’s most pressing crises—from food shortages to pandemic disease to climate change—and is paving the way for inventions once relegated to science fiction. Meanwhile, these advances are shedding new light on the biggest mystery of all—how did life begin? We know that every creature on Earth came from a single cell, sparked into existence four billion years ago. And as we come closer and closer to understanding the ancient root that connects all living things, we may finally be able to achieve a second genesis—the creation of new life where none existed before. Creation takes us on a journey four billion years in the making—from the very first cell to the ground-breaking biological inventions that will shape the future of our planet.

    The Hidden Half of Nature reveals why good health—for people and for plants—depends on Earth’s smallest creatures. Restoring life to their barren yard and recovering from a health crisis, David R. Montgomery and Anne Biklé discover astounding parallels between the botanical world and our own bodies. From garden to gut, they show why cultivating beneficial microbiomes holds the key to transforming agriculture and medicine.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    King (William and Mary University) delves into the story of how, why, where, and when we became human. These lectures will help you understand the forces that have shaped, and continue to shape, our species. "An evolutionary perspective on human behavior," notes Dr. King, "results in more than just knowledge about dates and sites when and where specific evolutionary milestones likely occurred." "It is also a window on the past and future of our species. An entirely new way of thinking comes into focus when we consider the human species within an evolutionary perspective."A Century of ScholarshipWhile covering these subjects in this 24-lecture series, Dr. King synthesizes the best that more than a century of scientific scholarship has to offer across a variety of disciplines. Biological anthropologists study primate anatomy and behavior both to understand evolution and to learn more about our common ancestor. Biological anthropologists are joined by molecular anthropologists to better understand hominids by studying fossils, ancient skeletal remains, and lifestyle information such as cave art and stone tools. Case Studies that Clarify Evolution and Its Power Dr. King begins by explaining key mechanisms through which evolution functions, citing famous and definitive case studies that demonstrate these forces. In one such landmark study, for example, biologists Peter and Rosemary Grant returned to the Galapagos Islands more than 100 years after Darwin's first voyage to conduct research on island finches. In 1977, a drought-induced scarcity of soft, edible seeds brought forth in the very next generation a population of finches with larger, stronger beaks capable of crushing larger, tougher seeds. Extraordinarily, in 1985, heavy rains produced a surplus of softer seeds, and natural selection produced a succeeding generation of the smaller-beaked variety. Evolution had occurred in two different directions within a decade. This "natural selection" is the theoretical tool of evolution, which helps us make sense of these facts. Why Evolution Remains Important to Us Today Perhaps the greatest measure of this theory's power is its relevance to our lives today. - Did you know that the gene which causes sickle cell anemia must be inherited from both parents to cause the disease but the disease does not occur when only a single gene is inherited? - Or that the single gene, in fact, affords protection from malaria? Or that race, a category so securely ingrained in our consciousness, is practically meaningless in biological terms? - Or how to evaluate the claim that a gene can be responsible for a certain personality trait? A Glimpse Into Our Selected Primate Heritage With an understanding of the basic mechanisms of evolutionary change in hand, the course looks at how our ancient primate ancestors adapted. Consider the anatomical features we share with monkeys, great apes, and other primates. Our large brains, grasping hands, and forward-facing eyes allowing us to perceive depth are critical to the way we function in the world. Yet the fossil record tells us that some 70 million years ago these distinctive primate features did not exist. What caused the first primates to emerge from existing mammalian populations? One proposed solution was that the appearance of insects living in the lower canopies of trees offered a plentiful food resource to those species adapted to procure it. Could depth perception and grasping ability have provided an advantage here, and hence been naturally selected? This is the function of biological anthropology: confronting the facts, then suggesting and testing possibilities. A Course as Much About the Present as the PastWith so much of evolutionary history taken up with the past, the insights gained in these lectures may tempt you to add questions of your own: - Is human evolution still a force in today's world? Hasn't our modern, mobile culture rendered evolution irrelevant? - In fact, human evolution is a stronger force than ever, interacting with human culture in complex ways. Issues such as obesity, AIDS, and genetics are all discussed. And you may well find these lectures opening your eyes to the extraordinary ways in which the biological power of natural selection is still at work in the world today. Course Lecture Titles1. What is Biological Anthropology? 2. How Evolution Works 3. The Debate Over Evolution 4. Matter Arising—New Species 5. Prosimians, Monkeys, and Apes 6. Monkey and Ape Social Behavior 7. The Mind of the Great Ape 8. Models for Human Ancestors? 9. Introducing the Hominids 10. Lucy and Company 11. Stones and Bones 12. Out of Africa 13. Who Were the Neandertals? 14. Did Hunting Make Us Human? 15. The Prehistory of Gender 16. Modern Human Anatomy and Behavior 17. On the Origins of Homo sapiens 18. Language 19. Do Human Races Exist? 20. Modern Human Variation 21. Body Fat, Diet, and Obesity 22. The Body and Mind Evolving 23. Tyranny of the Gene? 24. Evolution and Our Future

    Etcoff, a faculty member at Harvard Medical School and a practicing psychologist at Massachusetts General Hospital, skewers the enduring myth that the pursuit of beauty is a learned behavior.Etcoff puts forth that beauty is neither a cultural construction, an invention of the fashion industry, nor a backlash against feminism, but instead is in our biology. It's an essential and ineradicable part of human nature that is revered and ferociously pursued in nearly every civilizatoin--and for good reason. Those features to which we are most attracted are often signals of fertility and fecundity. When seen in the context of a Darwinian struggle for survival, our sometimes extreme attempts to attain beauty--both to become beautiful ourselves and to acquire an attractive partner--become understandable. Moreover, if we come to understand how the desire for beauty is innate, then we can begin to work in our interests, and not soley for the interests of our genetic tendencies.