She shows how the stalling of early twentieth century efforts in this direction allowed Freudians and social scientists to insist, with some justification, that they had better ways of analyzing and fixing minds.But when the Freudians overreached, they drove psychiatry into a state of crisis that a new “biological revolution” was meant to alleviate. Harrington shows how little that biological revolution had to do with breakthroughs in science, and why the field has fallen into a state of crisis in our own time.Mind Fixers makes clear that psychiatry’s waxing and waning biological enthusiasms have been shaped not just by developments in the clinic and lab, but also by a surprising range of social factors, including immigration, warfare, grassroots activism, and assumptions about race and gender. Government programs designed to empty the state mental hospitals, acrid rivalries between different factions in the field, industry profit mongering, consumerism, and an uncritical media have all contributed to the story as well.In focusing particularly on the search for the biological roots of schizophrenia, depression, and bipolar disorder, Harrington underscores the high human stakes for the millions of people who have sought medical answers for their mental suffering. This is not just a story about doctors and scientists, but about countless ordinary people and their loved ones.A clear-eyed, evenhanded, and yet passionate tour de force, Mind Fixers recounts the past and present struggle to make mental illness a biological problem in order to lay the groundwork for creating a better future, both for those who suffer and for those whose job it is to care for them.

    Yet a real definition of “now” has eluded even the great Einstein. We know that time stretches and is affected by gravity and velocity. Yet, as eminent physicist Richard A. Muller points out, it is only today that we have all the physics at hand—relativity, entropy, entanglement, antimatter, and the Big Bang—to explain the flow of time. With these building blocks in place, Muller reaches a startling conclusion: our expanding universe is continuously creating not only new space but also new time. The front edge of this new time is what we call “now,” and this moment is truly unique—it is the only moment in which we can exercise our free will. Muller’s thought-provoking vision is a powerful counter to established theories in science and philosophy, and his arguments will spark major debate about the most fundamental assumptions of our universe.

    Edward Marriott’s dramatic, gripping new book gives you yet another thing to worry about.” —New York Plague. The very word carries an unholy resonance. No other disease can claim its apocalyptic power: it can lie dormant for centuries, only to resurface with nation-killing force. Here, with the high drama of an adventure tale, Edward Marriott unravels the story of this lethal disease: the historic battle to identify its source, the devastating effects of pandemics, and the prospects for new outbreaks. Marriott begins the trail in Hong Kong in the summer of 1894, when a plague diagnosis brought to the island two top scientists—Alexandre Yersin, a maverick Frenchman, and his Japanese rival, Shibasaburo Kitasato. Marriott interweaves the narrative of their fierce competition with vivid scenes of the scourge’s persistence: California in 1900; Surat, India, in 1994; and New York City sometime in the future.A masterly account of medical and human history, Plague is at once an instructive warning and a chilling read.

    Supersized life spans are going to radically alter society, and present an unprecedented opportunity to change our approach not only to old age but to all of life’s stages. The ramifications are just beginning to dawn on us.... yet in the meantime, we keep thinking about, and planning for, life as it used to be lived. In A Long Bright Future, longevity and aging expert Laura Carstensen guides us into the new possibilities offered by a longer life. She debunks the myths and misconceptions about aging that stop us from adequately preparing for the future both as individuals and as a society: that growing older is associated with loneliness and unhappiness, and that only the genetically blessed live well and long. She then focuses on other important components of a long life, including finances, health, social relationships, Medicare and Social Security, challenging our preconceived notions of “old age” every step of the way.

    To understand the universe in the far future, we must first describe its present state and structure on the grand scale, and how its present properties arose. Dr Islam explains these topics in an accessible way in the first part of the book. From this background he speculates about the future evolution of the universe and predicts the major changes that will occur. The author has largely avoided mathematical formalism and therefore the book is well suited to general readers with a modest background knowledge of physics and astronomy.

    Lorimer Moseley, is a compilation of hilarious stories and images intended to help explain the complexity of pain. These stories, while entertaining, are used as metaphors to explain key aspects of the biology of pain. 'Painful Yarns' is a perfect pre-read for 'Explain Pain'.

    Virtually every American, on one level or another, falls victim to the hype, intensity, and propaganda that accompanies political panic, regardless of their own personal affiliations. By highlighting the similarities between American political panics from the Salem witch hunt to present-day vehemence over issues such as Latino immigration, gay marriage, and the construction of mosques, Stein closely examines just what it is that causes us as a nation to overreact in the face of widespread and potentially profound change. This book also devotes chapters to African Americans, Native Americans, Catholics, Mormons, Jews, Chinese and Japanese peoples, Communists, Capitalists, women, and a highly turbulent but largely forgotten panic over Freemasons. Striking similarities in these diverse episodes are revealed in primary documents Stein has unearthed, in which statements from the past could easily be mistaken for statements today. As these similarities come to light, Stein reveals why some people become panicked over particular issues when others do not.

    and a PhD.  While he was a student, and later during his surgical internship at the Johns Hopkins Hospital, he began the series of animal experiments that led eventually to the world’s first transplantation of the human liver in 1963.Throughout his career, first at the University of Colorado and then at the University of Pittsburgh, he has aroused both worldwide admiration and controversy.  His technical innovations and medical genius have revolutionized the field, but Starzl has not hesitated to address the moral and ethical issues raised by transplantation.  In this book he clearly states his position on many hotly debated issues including brain death, randomized trials for experimental drugs, the costs of transplant operations, and the system for selecting organ recipients from among scores of desperately ill patients.There are many heroes in the story of transplantation, and many “puzzle people,” the patients who, as one journalist suggested, might one day be made entirely of various transplanted parts.  They are old and young, obscure and world famous.  Some have been taken into the hearts of America, like Stormie Jones, the brave and beautiful child from Texas.  Every patient who receives someone else’s organ - and Starzl remembers each one - is a puzzle.  “It was not just the acquisition of a new part,” he writes.  “The rest of the body had to change in many ways before the gift could be accepted.  It was necessary for the mind to see the world in a different way.”  The surgeons and physicians who pioneered transplantation were also changed: they too became puzzle people.  “Some were corroded or destroyed by the experience, some were sublimated, and none remained the same.”

    Dennett has engaged questions about science and the workings of the mind. His answers have combined rigorous argument with strong empirical grounding. And a lot of fun.Intuition Pumps and Other Tools for Thinking offers seventy-seven of Dennett’s most successful "imagination-extenders and focus-holders" meant to guide you through some of life’s most treacherous subject matter: evolution, meaning, mind, and free will. With patience and wit, Dennett deftly deploys his thinking tools to gain traction on these thorny issues while offering readers insight into how and why each tool was built.Alongside well-known favorites like Occam’s Razor and reductio ad absurdum lie thrilling descriptions of Dennett’s own creations: Trapped in the Robot Control Room, Beware of the Prime Mammal, and The Wandering Two-Bitser. Ranging across disciplines as diverse as psychology, biology, computer science, and physics, Dennett’s tools embrace in equal measure light-heartedness and accessibility as they welcome uninitiated and seasoned readers alike. As always, his goal remains to teach you how to "think reliably and even gracefully about really hard questions."A sweeping work of intellectual seriousness that’s also studded with impish delights, Intuition Pumps offers intrepid thinkers—in all walks of life—delicious opportunities to explore their pet ideas with new powers.

    K. C. Cole's "Fun with Physics" is a profile of astrophysicist Janet Conrad that blends her personal life with professional activity. In "Desperate Measures," the doctor and writer Atul Gawande profiles the surgeon Francis Daniels Moore, whose experiments in the 1940s and '50s pushed medicine harder and farther than almost anyone had contemplated. Also included is a poem by the legendary John Updike, "Mars as Bright as Venus." The collection ends with Diane Ackerman's "ebullient" essay "We Are All a Part of Nature."Together these twenty-three articles on a wide range of today's most current topics in science -- from biology, physics, biotechnology, and astronomy, to anthropology, genetics, evolutionary theory, and cognition‚ represent the full spectrum of scientific writing from America's most prominent science authors, proving once again that "good science writing is evidently plentiful" (Scientific American).

     In this masterful account of the 1995 Ebola outbreak in Zaire, Garrett, now the Senior Fellow for Global Health at the Council on Foreign Relations, shows how superstition and fear, compounded by a lack of resources, education, and clearheaded government planning have plagued our response to Ebola. In an extensive new introduction, Garrett forcefully argues that learning from past outbreaks is the key to solving the Ebola crisis of 2014. In her account of the 1995 Zaire outbreak, first published in her bestselling book Betrayal of Trust, Garrett takes readers through the epidemic's course-beginning with the Kikwit villager who first contracted it from an animal encounter while chopping wood for charcoal deep in the forest. As she documents the outbreak in riveting detail, Garrett shows why our trust in world governments to protect people's health has been irrevocably broken. She details the international community's engagement in the epidemic's aftermath: a pattern of response and abandonment, urgency that devolves into amnesia. Ebola: Story of an Outbreak is essential reading for anyone who wants to comprehend Ebola, one of mankind's most mysterious, malicious scourges. Garrett has issued a powerful call for governments, citizens, and the disease-fighting agencies of the wealthy world to take action.

    But such is Stephen Jay Gould's command of paleontology and evolutionary theory, and his gift for brilliant explication, that he has brought dust and dead bones to life, and developed an immense following for the seeming arcana of this field.In Time's Arrow, Time's Cycle his subject is nothing less than geology's signal contribution to human thought--the discovery of "deep time," the vastness of earth's history, a history so ancient that we can comprehend it only as metaphor. He follows a single thread through three documents that mark the transition in our thinking from thousands to billions of years: Thomas Burnet's four-volume Sacred Theory of the Earth (1680-1690), James Hutton's Theory of the Earth (1795), and Charles Lyell's three-volume Principles of Geology (1830-1833).Gould's major theme is the role of metaphor in the formulation and testing of scientific theories--in this case the insight provided by the oldest traditional dichotomy of Judeo-Christian thought: the directionality of time's arrow or the immanence of time's cycle. Gould follows these metaphors through these three great documents and shows how their influence, more than the empirical observation of rocks in the field, provoked the supposed discovery of deep time by Hutton and Lyell. Gould breaks through the traditional "cardboard" history of geological textbooks (the progressive march to truth inspired by more and better observations) by showing that Burnet, the villain of conventional accounts, was a rationalist (not a theologically driven miracle-monger) whose rich reconstruction of earth history emphasized the need for both time's arrow (narrative history) and time's cycle (immanent laws), while Hutton and Lyell, our traditional heroes, denied the richness of history by their exclusive focus upon time's Arrow.

    Based on selective breeding of human beings, eugenics began in laboratories on Long Island but ended in the concentration camps of Nazi Germany. Cruel and racist laws were enacted in 27 U.S. states, while the supporters of eugenics included progressive thinkers like Woodrow Wilson, Margaret Sanger and Oliver Wendell Holmes. Ultimately, over 60,000 "unfit" Americans were coercively sterilized, a third of them after Nuremberg had declared such practices crimes against humanity. This is a timely and shocking chronicle of bad science at its worst—with many important lessons for the genetic age in which an interest in eugenics has been dangerously revived.

    And two giants at the foundations of modern science were converging, step-by-step, on the answer: Albert Einstein, an young, obscure German physicist experimenting with measuring time using telegraph networks and with the coordination of clocks at train stations; and the renowned mathematician Henri Poincaré, president of the French Bureau of Longitude, mapping time coordinates across continents. Each found that to understand the newly global world, he had to determine whether there existed a pure time in which simultaneity was absolute or whether time was relative.Esteemed historian of science Peter Galison has culled new information from rarely seen photographs, forgotten patents, and unexplored archives to tell the fascinating story of two scientists whose concrete, professional preoccupations engaged them in a silent race toward a theory that would conquer the empire of time.

    Learn about trepanation, the COVID-19 pandemic, Norovirus, Chickenpox, Diabetes, and more, all inspired by Sawbones 300+ podcast episodes. Wondering whether eating powdered mummies might be just the thing to cure your ills? Tempted by those vintage ads suggesting you wear radioactive underpants for virility? Ever considered drilling a hole in your head to deal with those pesky headaches? Probably not! But for thousands of years, people have done things like this—and things that make radioactive underpants seem downright sensible! In their hit podcast, Sawbones, Sydnee and Justin McElroy breakdown the weird and wonderful way we got to modern healthcare . . . and some of the terrifying detours along the way. Every week, Dr. Sydnee McElroy and her husband Justin amaze, amuse, and gross out (depending on the week) hundreds of thousands of avid listeners to their podcast, Sawbones. Consistently rated a top podcast on iTunes, with over 15 million total downloads, this rollicking journey through thousands of years of medical mishaps and miracles is not only hilarious but downright educational. While you may never even consider applying  boiled weasel to your forehead (once the height of sophistication when it came to headache cures), you will almost certainly face some questionable medical advice in your everyday life (we’re looking at you, raw water!) and be better able to figure out if this is a miracle cure (it’s not) or a scam. Table of Contents: Part 1: The Contagious Quarantine The Deadly Parade Detox The Black Plague Pliny the Elder The Man Who Drank Poop Parrot Fever Part II: The Unnvering The Resurrection Men Opium An Electrifying Experience Weight Loss Charcoal Erectile Dysfunction Spontaneous Combustion Trepanation The Doctor Is In Part III: The Gross Mummy Medicine Mercury The Guthole Bromance A Piece of Your Mind The Unkillable Phineas Gage Phrenology Robert Liston Urine Luck! Radium Humorism The Straight Poop The Doctor Is In Part IV: The Weird The Dancing Plague Curtis Howe Springer Smoke 'Em if You Got 'Em A Titanic Case of Nausea Arsenic Paracelsus Honey Self-Experimentation Homeopathy The Doctor Is In Part V: The Awesome The Poison Squad Bloodletting Death by Chocolate John Harvey Kellogg Vinegar Polio Vaccine The Doctor Is In