But a medical revolution is underway that can solve this problem: Astonishing new research is revealing that the health of your brain is, to an extraordinary degree, dictated by the state of your microbiome - the vast population of organisms that live in your body and outnumber your own cells ten to one. What's taking place in your intestines today is determining your risk for any number of brain-related conditions.In BRAIN MAKER, Dr. Perlmutter explains the potent interplay between intestinal microbes and the brain, describing how the microbiome develops from birth and evolves based on lifestyle choices, how it can become "sick," and how nurturing gut health through a few easy strategies can alter your brain's destiny for the better. With simple dietary recommendations and a highly practical program of six steps to improving gut ecology, BRAIN MAKER opens the door to unprecedented brain health potential.

    They’ve all been solved.” Fortunately, Piot ignored him, and the result has been an exceptional, adventure-filled career. In the 1970s, as a young man, Piot was sent to Central Africa as part of a team tasked with identifying a grisly new virus. Crossing into the quarantine zone on the most dangerous missions, he studied local customs to determine how this disease—the Ebola virus—was spreading. Later, Piot found himself in the field again when another mysterious epidemic broke out: AIDS. He traveled throughout Africa, leading the first international AIDS initiatives there. Then, as founder and director of UNAIDS, he negotiated policies with leaders from Fidel Castro to Thabo Mbeki and helped turn the tide of the epidemic. Candid and engrossing, No Time to Lose captures the urgency and excitement of being on the front lines in the fight against today’s deadliest diseases.

    Ballet dancers and rock musicians, professors and thieves-"anyone who had fallen, or, often, leapt, onto hard times" and needed extended medical care-ended up here. So did Victoria Sweet, who came for two months and stayed for twenty years. Laguna Honda, lower tech but human paced, gave Sweet the opportunity to practice a kind of attentive medicine that has almost vanished. Gradually, the place transformed the way she understood her work. Alongside the modern view of the body as a machine to be fixed, her extraordinary patients evoked an older idea, of the body as a garden to be tended. God's Hotel tells their story and the story of the hospital itself, which, as efficiency experts, politicians, and architects descended, determined to turn it into a modern "health care facility," revealed its own surprising truths about the essence, cost, and value of caring for body and soul.

    It proved fatal to at least a half-million Americans. Yet, the Spanish flu pandemic is largely forgotten today. In this vivid narrative, Alfred W. Crosby recounts the course of the pandemic during the panic-stricken months of 1918 and 1919, measures its impact on American society, and probes the curious loss of national memory of this cataclysmic event. In a new edition, with a new preface discussing the recent outbreaks of diseases, including the Asian flu and the SARS epidemic, America's Forgotten Pandemic remains both prescient and relevant. Alfred W. Crosby is a Professor Emeritus in American Studies, History and Geography at the University of Texas at Austin, where he taught for over 20 years. His previous books include Throwing Fire (Cambrige, 2002), the Measure of Reality (Cambridge, 1997) and Ecological Imperialism (cambridge, 1986). Ecological Imperialism was the winner of the 1986 Phi Beta Kappa book prize. The Measure of Reality was chosen by the Los Angeles Times as one of the 100 most important books of 1997.

    The Tuskegee Study had nothing to do with treatment. Its purpose was to trace the spontaneous evolution of the disease in order to learn how syphilis affected black subjects.The men were not told they had syphilis; they were not warned about what the disease might do to them; and, with the exception of a smattering of medication during the first few months, they were not given health care. Instead of the powerful drugs they required, they were given aspirin for their aches and pains. Health officials systematically deceived the men into believing they were patients in a government study of “bad blood”, a catch-all phrase black sharecroppers used to describe a host of illnesses. At the end of this 40 year deathwatch, more than 100 men had died from syphilis or related complications.“Bad Blood” provides compelling answers to the question of how such a tragedy could have been allowed to occur. Tracing the evolution of medical ethics and the nature of decision making in bureaucracies, Jones attempted to show that the Tuskegee Study was not, in fact, an aberration, but a logical outgrowth of race relations and medical practice in the United States.Now, in this revised edition of “Bad Blood”, Jones traces the tragic consequences of the Tuskegee Study over the last decade. A new introduction explains why the Tuskegee Study has become a symbol of black oppression and a metaphor for medical neglect, inspiring a prize-winning play, a Nova special, and a motion picture. A new concluding chapter shows how the black community's wide-spread anger and distrust caused by the Tuskegee Study has hampered efforts by health officials to combat AIDS in the black community. “Bad Blood” was nominated for the Pulitzer Prize and was one of the “N.Y. Times” 12 best books of the year.

    This trial serves as the backdrop for Superbugs, and the results will impact nothing less than the future of humanity.Dr. McCarthy explores the history of bacteria and antibiotics, from Alexander Fleming's discovery of penicillin, to obscure sources of innovative new medicines (often found in soil samples), to the cutting-edge DNA manipulation known as CRISPR, bringing to light how we arrived at this juncture of both incredible breakthrough and extreme vulnerability. We also meet the patients whose lives are hanging in the balance, from Remy, a teenager with a dangerous and rare infection, to Donny, a retired New York City firefighter with a compromised immune system, and many more.

    Working in the kitchens of the upper class, she left a trail of disease in her wake, until one enterprising and ruthless “medical engineer” proposed the inconceivable notion of the “asymptomatic carrier”—and from then on Mary Mallon was a hunted woman. In order to keep New York’s citizens safe from Mallon, the Department of Health sent her to North Brother Island where she was kept in isolation from 1907-1910. She was released under the condition that she never work as a cook again. Yet for Mary—spoiled by her status and income and genuinely passionate about cooking—most domestic and factory jobs were heinous. She defied the edict.Bringing early twentieth-century New York alive—the neighborhoods, the bars, the park being carved out of upper Manhattan, the emerging skyscrapers, the boat traffic—Fever is as fiercely compelling as Typhoid Mary herself, an ambitious retelling of a forgotten life. In the hands of Mary Beth Keane, Mary Mallon becomes an extraordinarily dramatic, vexing, sympathetic, uncompromising, and unforgettable character.

    Indeed, most are only barely aware of the diseases caused by them, except, perhaps, for mad cow disease. Yet prions are the stuff of a revolutionary science?a science that might lead to cures for some of humankind?s most devastating diseases.Fatal Flaws is a scientific detective story about this elusive protein, starting with the discovery of kuru, a disease unique to New Guinea in the 1950s that baffled scientists and carried with it whispers of cannibalism. Kuru began a scientific stampede to seek out the agent of this mysterious disease?the prion?a misfolded protein whose existence some of the world?s top scientists still find difficult to accept. Today, the subject of prions remains controversial, yet the proteins might promise new treatments for some of the most intractable brain diseases, ones that affect millions around the planet, including Parkinson?s, ALS and Alzheimer?s.In Fatal Flaws, Jay Ingram unties a complicated interweaving of biology, medicine, human tragedy, surprise and disbelief in the world of prions, and he unravels some of history?s most stunning revelations about disease, the brain and infection.

    As the mosquito transformed the landscapes of civilization, humans were unwittingly required to respond to its piercing impact and universal projection of power.The mosquito has determined the fates of empires and nations, razed and crippled economies, and decided the outcome of pivotal wars, killing nearly half of humanity along the way. She (only females bite) has dispatched an estimated 52 billion people from a total of 108 billion throughout our relatively brief existence. As the greatest purveyor of extermination we have ever known, she has played a greater role in shaping our human story than any other living thing with which we share our global village.Imagine for a moment a world without deadly mosquitoes, or any mosquitoes, for that matter? Our history and the world we know, or think we know, would be completely unrecognizable.Driven by surprising insights and fast-paced storytelling, The Mosquito is the extraordinary untold story of the mosquito's reign through human history and her indelible impact on our modern world order.

    Doctors stymied by mysterious symptoms of the killer: soaring temperature, painful backache, swelling of the throat and neck, discolored skin! Latest victim airlifted to special isolation ward at New York's Columbia Presbyterian Hospital, blood samples rushed to Yale's Arborvirus Laboratory, all-out search launches to discover an antidote. U. S. Public Health officials alarmed, virus has the potential to decimate the whole population, aviation officials consider cancellation of all jet travel to critical world areas.

    Belknap's Waterproof Grand Canyon River Guide (All New Color Edition)

    Fuzzy sonograms and doctor's explanations can provide basic information, but through Alexander Tsiaras' remarkable achievements in medical imaging technology, parents can see, for the first time, the awe-inspiring process of a new life unfolding, in stunning, vivid detail.The milestones of pregnancy which before could only be described can now be witnessed: the heart's first beats; the appearance of color in the eye; the emergence of toes and teeth; the brain and nervous system directing development; the first movement of tiny legs and arms; the first indications of gender; the wondrous symbiosis of mother and child; the symphony of the body's systems coming into being and working in concert. The book tracks the development of a baby from the moment of conception, through the explosively complex early stages of development and the amazing stages of growth as the baby is nurtured by the mother, ending with the joy of birth.All this is made possible by revolutions in two sciences. As biologists have decoded the molecular basis of life, computer scientists have developed non-invasive, three-dimensional techniques for visualizing the body. Alexander Tsiaras has been a pioneer in merging these explorations and discoveries. He has created a virtual camera studio that enables him to view a human body or any part of it individually, scan it, enlarge it, rotate it, adjust its transparency so that we can view inside a living being, and light it from any angle. The result is an ability to illuminate the unseen elements that make us who we are, and the miraculous images in From Conception to Birth.

    In this fully updated and revised edition, diabetes educator Gary Scheiner provides the tools to “think like a pancreas”—to successfully master the art and science of matching insulin to the body’s ever-changing needs. Comprehensive, free of medical jargon, and packed with useful information not readily available elsewhere, this new edition covers the many strides taken in diabetes education and management since the first edition seven years ago. Think Like a Pancreas includes critical information, such as day-to-day blood glucose control and monitoring, designing an insulin program to best match your lifestyle, up-to date medication and technology, and new insulin formulations and combinations.

    Jonathan Reiner, share the story of Cheney’s thirty-five-year battle with heart disease—providing insight into the incredible medical breakthroughs that have changed cardiac care over the last four decades. For as long as he has served at the highest levels of business and government, Vice President Dick Cheney has also been one of the world’s most prominent heart patients. Now, for the first time ever, Cheney, together with his longtime cardiologist, Jonathan Reiner, MD, shares the very personal story of his courageous thirty-five-year battle with heart disease, from his first heart attack in 1978 to the heart transplant he received in 2012.In 1978, when Cheney suffered his first heart attack, he received essentially the same treatment President Eisenhower had had in 1955. Since then, cardiac medicine has been revolutionized, and Cheney has benefitted from nearly every medical breakthrough. At each juncture, when Cheney faced a new health challenge, the technology was one step ahead of his disease. Cheney’s story is in many ways the story of the evolution of modern cardiac care.Heart is the riveting, singular memoir of both doctor and patient. Like no US politician has before him, Cheney opens up about his health struggles, sharing harrowing, never-before-told stories about the challenges he faced during a perilous time in our nation’s history. Dr. Reiner provides his perspective on Cheney’s case and also gives readers a fascinating glimpse into his own education as a doctor and the history of our understanding of the human heart. He masterfully chronicles the important discoveries, radical innovations, and cutting-edge science that have changed the face of medicine and saved countless lives.Powerfully braiding science with story and the personal with the political, Heart is a sweeping, inspiring, and ultimately optimistic book that will give hope to the millions of Americans affected by heart disease.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future