As a result, antibiotic resistance now ranks among the gravest medical problems of modern times. Good Germs, Bad Germs addresses not only this issue but also what has become known as the "hygiene hypothesis"-- an argument that links the over-sanitation of modern life to now-epidemic increases in immune and other disorders. In telling the story of what went terribly wrong in our war on germs, Jessica Snyder Sachs explores our emerging understanding of the symbiotic relationship between the human body and its resident microbes--which outnumber its human cells by a factor of nine to one! The book also offers a hopeful look into a future in which antibiotics will be designed and used more wisely, and beyond that, to a day when we may replace antibacterial drugs and cleansers with bacterial ones--each custom-designed for maximum health benefits.

    But by itself, DNA is just an inert blueprint for life. It is the ribosome--an enormous molecular machine made up of a million atoms--that makes DNA come to life, turning our genetic code into proteins and therefore into us. Gene Machine is an insider account of the race for the structure of the ribosome, a fundamental discovery that both advances our knowledge of all life and could lead to the development of better antibiotics against life-threatening diseases. But this is also a human story of Ramakrishnan's unlikely journey, from his first fumbling experiments in a biology lab to being the dark horse in a fierce competition with some of the world's best scientists. In the end, Gene Machine is a frank insider's account of the pursuit of high-stakes science.

    Lieberman illuminates how these ongoing changes have brought many benefits, but also have created novel conditions to which our bodies are not entirely adapted, resulting in a growing incidence of obesity and new but avoidable diseases, including type-2 diabetes. He proposes that many of these chronic illnesses persist and in some cases are intensifying because of "dysevolution," a pernicious dynamic whereby only the symptoms rather than the causes of these maladies are treated. And finally—provocatively—he advocates the use of evolutionary information to help nudge, push, and sometimes oblige us to create a more salubrious environment.(With charts and line drawings throughout.)From the Hardcover edition.

    They have brains that are huge for their body size and exhibit an avian kind of eloquence. They mate for life and associate with relatives and neighbors for years. And because they often live near people—in our gardens, parks, and cities—they are also keenly aware of our peculiarities, staying away from and even scolding anyone who threatens or harms them and quickly learning to recognize and approach those who care for and feed them, even giving them numerous, oddly touching gifts in return. With his extraordinary research on the intelligence and startling abilities of corvids—crows, ravens, and jays—scientist John Marzluff teams up with artist-naturalist Tony Angell to tell amazing stories of these brilliant birds in Gifts of the Crow. With narrative, diagrams, and gorgeous line drawings, they offer an in-depth look at these complex creatures and our shared behaviors. The ongoing connection between humans and crows—a cultural coevolution—has shaped both species for millions of years. And the characteristics of crows that allow this symbiotic relationship are language, delinquency, frolic, passion, wrath, risk-taking, and awareness—seven traits that humans find strangely familiar. Crows gather around their dead, warn of impending doom, recognize people, commit murder of other crows, lure fish and birds to their death, swill coffee, drink beer, turn on lights to stay warm, design and use tools, use cars as nutcrackers, windsurf and sled to play, and work in tandem to spray soft cheese out of a can. Their marvelous brains allow them to think, plan, and reconsider their actions. With its abundance of funny, awe-inspiring, and poignant stories, Gifts of the Crow portrays creatures who are nothing short of amazing. A testament to years of painstaking research and careful observation, this fully illustrated, riveting work is a thrilling look at one of nature’s most wondrous creatures.

    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

    How many of us understand the way seizures affect the brain, how the heart is connected to wellbeing, or the why the foot carries the key to our humanity? In Adventures in Human Being, award-winning author Gavin Francis leads readers on a journey into the hidden pathways of the human body, offering a guide to its inner workings and a celebration of its marvels.Drawing on his experiences as a surgeon, ER specialist, and family physician, Francis blends stories from the clinic with episodes from medical history, philosophy, and literature to describe the body in sickness and in health, in living and in dying. At its heart, Adventures in Human Being is a meditation on what it means to be human. Poetic, eloquent, and profoundly perceptive, this book will transform the way you view your body.

    From the #1 bestselling author of The Hot Zone comes an amazing account of scientific and spiritual passion for the tallest trees in the world, the startling biosystem of Rthe canopy, S and those who are committed to the preservation of this astonishing and largely unknown world.

    In his groundbreaking Before the Dawn, Wade reveals humanity's origins as never before--a journey made possible only recently by genetic science, whose incredible findings have answered such questions as: What was the first human language like? How large were the first societies, and how warlike were they? When did our ancestors first leave Africa, and by what route did they leave? By eloquently solving these and numerous other mysteries, Wade offers nothing less than a uniquely complete retelling of a story that began 500 centuries ago.

    Most conservationists and environmentalists share this view. But what if the traditional view of ecology is wrong—what if true environmentalists should be applauding the invaders? In The New Wild, Pearce goes on a journey across six continents to rediscover what conservation in the twenty-first century should be about. Pearce explores ecosystems from remote Pacific islands to the United Kingdom, from San Francisco Bay to the Great Lakes, as he digs into questionable estimates of the cost of invader species and reveals the outdated intellectual sources of our ideas about the balance of nature. Pearce acknowledges that there are horror stories about alien species disrupting ecosystems, but most of the time, the tens of thousands of introduced species usually swiftly die out or settle down and become model eco-citizens. The case for keeping out alien species, he finds, looks increasingly flawed. As Pearce argues, mainstream environmentalists are right that we need a rewilding of the earth, but they are wrong if they imagine that we can achieve that by reengineering ecosystems. Humans have changed the planet too much, and nature never goes backward. But a growing group of scientists is taking a fresh look at how species interact in the wild. According to these new ecologists, we should applaud the dynamism of alien species and the novel ecosystems they create. In an era of climate change and widespread ecological damage, it is absolutely crucial that we find ways to help nature regenerate. Embracing the new ecology, Pearce shows us, is our best chance. To be an environmentalist in the twenty-first century means celebrating nature’s wildness and capacity for change.

    Written while Abbey was working as a ranger at Arches National Park outside of Moab, Utah, Desert Solitaire is a rare view of one man’s quest to experience nature in its purest form.Through prose that is by turns passionate and poetic, Abbey reflects on the condition of our remaining wilderness and the future of a civilization that cannot reconcile itself to living in the natural world as well as his own internal struggle with morality. As the world continues its rapid development, Abbey’s cry to maintain the natural beauty of the West remains just as relevant today as when this book was written.

    Humans have "subdued 75 per cent of the land surface, concocted a wizardry of industrial and medical marvels, strung lights all across the darkness." We now collect the DNA of vanishing species in a "frozen ark," equip orangutans with iPads, create wearable technologies and synthetic species that might one day outsmart us. With her distinctive gift for making scientific discovery intelligible to the layperson, Ackerman takes us on an exciting journey to understand this bewildering new reality, introducing us to many of the people and ideas now creating--perhaps saving--the future.The Human Ageis a surprising, optimistic engagement with the dramatic transformations that have shaped, and continue to alter, our world, our relationship with nature and our prospects for the future.

    In this amazingly comprehensible history of the universe, Simon Singh decodes the mystery behind the Big Bang theory, lading us through the development of one of the most extraordinary, important, and awe-inspiring theories in science.

    The Structure of Scientific Revolutions is that kind of book. When it was first published in 1962, it was a landmark event in the history and philosophy of science. Fifty years later, it still has many lessons to teach. With The Structure of Scientific Revolutions, Kuhn challenged long-standing linear notions of scientific progress, arguing that transformative ideas don’t arise from the day-to-day, gradual process of experimentation and data accumulation but that the revolutions in science, those breakthrough moments that disrupt accepted thinking and offer unanticipated ideas, occur outside of “normal science,” as he called it. Though Kuhn was writing when physics ruled the sciences, his ideas on how scientific revolutions bring order to the anomalies that amass over time in research experiments are still instructive in our biotech age. This new edition of Kuhn’s essential work in the history of science includes an insightful introduction by Ian Hacking, which clarifies terms popularized by Kuhn, including paradigm and incommensurability, and applies Kuhn’s ideas to the science of today. Usefully keyed to the separate sections of the book, Hacking’s introduction provides important background information as well as a contemporary context.  Newly designed, with an expanded index, this edition will be eagerly welcomed by the next generation of readers seeking to understand the history of our perspectives on science.

    A stunning collection of personal observations that uses images of the American West to probe larger concerns in lyrical, evocative prose that is a true celebration of the region.

    That same season, The Great Salt Lake began to rise to record heights, threatening the herons, owls, and snowy egrets that Williams, a poet and naturalist, had come to gauge her life by. One event was nature at its most random, the other a by-product of rogue technology: Terry's mother, and Terry herself, had been exposed to the fallout of atomic bomb tests in the 1950s. As it interweaves these narratives of dying and accommodation, Refuge transforms tragedy into a document of renewal and spiritual grace, resulting in a work that has become a classic.