After years of misdiagnoses, doctors discovered a deadly blockage in her liver. Struggling to find  an explanation for her unusual condition, Joselin compared the medical chart of her father—who had died from a mysterious disease, ten years prior—with that of an uncle who had died under similarly strange circumstances. Delving further into the past, she discovered that her great-grandmother had displayed symptoms similar to hers before her death. Clearly, this was more than a fluke. Setting out to build a more complete picture of the illness that haunted her family, Joselin approached Dr. Christine Seidman, the head of a group of world-class genetic researchers at Harvard Medical School, for help. Dr. Seidman had been working on her family’s case for twenty years and had finally confirmed that fourteen of Joselin’s relatives carried something called a private mutation—meaning that they were the first known people to experience the baffling symptoms of a brand new genetic mutation. Here, Joselin tells the story of their gene: the lives it claimed and the future of genomic medicine with the potential to save those that remain. Digging into family records and medical history, conducting interviews with relatives and friends, and reflecting on her own experiences with the Harvard doctor, Joselin pieces together the lineage of this deadly gene to write an exploration of family, history, and love.

    The name alone conjures images of chestnut-lined boulevards, sidewalk cafés, breathtaking façades around every corner--in short, an exquisite romanticism that has captured the American imagination for as long as there have been Americans.In 1995, Adam Gopnik, his wife, and their infant son left the familiar comforts and hassles of New York City for the urbane glamour of the City of Light. Gopnik is a longtime New Yorker writer, and the magazine has sent its writers to Paris for decades--but his was above all a personal pilgrimage to the place that had for so long been the undisputed capital of everything cultural and beautiful. It was also the opportunity to raise a child who would know what it was to romp in the Luxembourg Gardens, to enjoy a croque monsieur in a Left Bank café--a child (and perhaps a father, too) who would have a grasp of that Parisian sense of style we Americans find so elusive.So, in the grand tradition of the American abroad, Gopnik walked the paths of the Tuileries, enjoyed philosophical discussions at his local bistro, wrote as violet twilight fell on the arrondissements. Of course, as readers of Gopnik's beloved and award-winning "Paris Journals" in The New Yorker know, there was also the matter of raising a child and carrying on with day-to-day, not-so-fabled life. Evenings with French intellectuals preceded middle-of-the-night baby feedings; afternoons were filled with trips to the Musée d'Orsay and pinball games; weekday leftovers were eaten while three-star chefs debated a "culinary crisis."As Gopnik describes in this funny and tender book, the dual processes of navigating a foreign city and becoming a parent are not completely dissimilar journeys--both hold new routines, new languages, a new set of rules by which everyday life is lived. With singular wit and insight, Gopnik weaves the magical with the mundane in a wholly delightful, often hilarious look at what it was to be an American family man in Paris at the end of the twentieth century. "We went to Paris for a sentimental reeducation - I did anyway - even though the sentiments we were instructed in were not the ones we were expecting to learn, which I believe is why they call it an education."

    In this extraordinary memoir, she opens a window into the experience of wordlessness—the language paralysis called aphasia. In narrating the recovery of her husband, Paul West, from a stroke that reduced his vast vocabulary to a single syllable, she evokes the joy and mystery of the brain’s ability to find and connect words. Deeply rewarding to readers of all kinds, Ackerman has given us a literary love story, accessible insight into the science and medicine of brain injury,and invaluable spiritual sustenance in the face of life’s myriad physical sufferings.

    He buried it and told me I must never tell. It was the only thing we’d ever done together as father and son, and I promised not to tell. But unlike most dreams, the memory of this one never left me. And sometimes…I wasn’t altogether sure about one thing: was it just a dream?”When Augusten Burroughs was small, his father was a shadowy presence in his life: a form on the stairs, a cough from the basement, a silent figure smoking a cigarette in the dark. As Augusten grew older, something sinister within his father began to unfurl.  Something dark and secretive that could not be named. Betrayal after shocking betrayal ensued, and Augusten’s childhood was over. The kind of father he wanted didn’t exist for him. This father was distant, aloof, uninterested…And then the “games” began.With "A Wolf at the Table", Augusten Burroughs makes a quantum leap into untapped emotional terrain: the radical pendulum swing between love and hate, the unspeakably terrifying relationship between father and son. Told with scorching honesty and penetrating insight, it is a story for anyone who has ever longed for unconditional love from a parent. Though harrowing and brutal, "A Wolf at the Table" will ultimately leave you buoyed with the profound joy of simply being alive. It’s a memoir of stunning psychological cruelty and the redemptive power of hope.

    Not knowing the name of his family or where he was from, he survived for weeks on the streets of Kolkata, before being taken into an orphanage and adopted by a couple in Australia.Despite being happy in his new family, Saroo always wondered about his origins. He spent hours staring at the map of India on his bedroom wall. When he was a young man the advent of Google Earth led him to pore over satellite images of the country for landmarks he recognised. And one day, after years of searching, he miraculously found what he was looking for.Then he set off on a journey to find his mother.

    What surfaced was terrifying: she was inhabited by 'the Troops'-92 individual personalities. This groundbreaking true story is made all the more extraordinary in that it was written by the Troops themselves. What they reveal is a spellbinding descent into a personal hell-and an ultimate deliverance for the woman they became.

    She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.

     A shy manifesto, an impractical handbook, the true story of a fabulist, an entire life in parts and pieces, Manhood for Amateurs is the first sustained work of personal writing from Michael Chabon. In these insightful, provocative, slyly interlinked essays, one of our most brilliant and humane writers presents his autobiography and his vision of life in the way so many of us experience our own lives: as a series of reflections, regrets, and reexaminations, each sparked by an encounter, in the present, that holds some legacy of the past. What does it mean to be a man today? Chabon invokes and interprets and struggles to reinvent for us, with characteristic warmth and lyric wit, the personal and family history that haunts him even as--simply because--it goes on being written every day. As a devoted son, as a passionate husband, and above all as the father of four young Americans, Chabon presents his memories of childhood, of his parents' marriage and divorce, of moments of painful adolescent comedy and giddy encounters with the popular art and literature of his own youth, as a theme played--on different instruments, with a fresh tempo and in a new key--by the mad quartet of which he now finds himself co-conductor. At once dazzling, hilarious, and moving, Manhood for Amateurs is destined to become a classic.

    The center of Tamara’s universe is Shopsin’s, her family’s legendary corner store/restaurant/hangout, run by her inimitable dad, Kenny—a brilliant, loquacious, contrary, huge-hearted man who, aside from dishing up New York’s best egg salad on rye, is Village sheriff, philosopher, and fixer all at once. We follow Kenny as he pursues his destiny through early factory jobs, superintendent gigs, and crossword-puzzle mania. His temper flares as often as his humor, keeping Tamara, her mom, and her siblings constantly off-balance but giddy to be along for the always bracing ride. And the cast of supporting characters is unforgettable—oddballs and misfits, cops and con men, sax players and waitresses, longshoremen and poets, and crafty Willoughby “Willy” Jones, an old-time swindler and lady-killer from the South who improbably becomes Kenny’s foil and best friend. All comers find a place at Shopsin’s table and feast on Kenny’s tall tales and trenchant advice along with the incomparable chili con carne.At its core, Arbitrary Stupid Goal is about the secrets of living an unconventional life, which is becoming a forgotten art. It’s a place where serendipity trumps logic and overplanning can cause you to miss out on the fun of a midnight walk to the giant bubbling margarita glass perched precariously over the Mexican joint on Seventh Avenue. It’s about taking the day as it flows, treasuring experiences over things, and embracing the crazy but essential messiness of relationships.Filled with clever illustrations and witty, nostalgic photographs and graphics, and told in a sly, elliptical narrative that is both hilarious and endearing, Arbitrary Stupid Goal is an offbeat memory-book mosaic that will encourage readers to rediscover the vital spontaneity that we may have unwisely traded for the shelter of predictability.

    Yearning for more tangible work, she applied for a job she saw on Craigslist—Carpenter’s Assistant: Women strongly encouraged to apply—despite being a Classics major who couldn't tell a Phillips from a flathead screwdriver. She got the job, and in Hammer Head she tells the rich and entertaining story of becoming a carpenter.Writing with infectious curiosity, MacLaughlin describes the joys and frustrations of making things by hand, reveals the challenges of working as a woman in an occupation that is 99 percent male, and explains how manual labor changed the way she sees the world. We meet her unflappable mentor, Mary, a petite but tough carpenter-sage (“Be smarter than the tools!”), as well as wild demo dudes, foul-mouthed plumbers, grizzled hardware store clerks, and the colorful clients whose homes she and Mary work in.Whisking her readers from job to job—building a wall, remodeling a kitchen, gut-renovating a house—MacLaughlin examines the history of the tools she uses and the virtues and varieties of wood. Throughout, she draws on the wisdom of Ovid, Annie Dillard, Studs Terkel, and Mary Oliver to illuminate her experience of work. And, in a deeply moving climax, MacLaughlin strikes out on her own for the first time to build bookshelves for her own father.Hammer Head is a passionate book full of sweat, swearing, bashed thumbs, and a deep sense of finding real meaning in work and life.

    Allen Ginsberg. William S. Burroughs. LeRoi Jones. Theirs are the names primarily associated with the Beat Generation. But what about Joyce Johnson (nee Glassman), Edie Parker, Elise Cowen, Diane Di Prima, and dozens of others? These female friends and lovers of the famous iconoclasts are now beginning to be recognized for their own roles in forging the Beat movement and for their daring attempts to live as freely as did the men in their circle a decade before Women's Liberation.Twenty-one-year-old Joyce Johnson, an aspiring novelist and a secretary at a New York literary agency, fell in love with Jack Kerouac on a blind date arranged by Allen Ginsberg nine months before the publication of On the Road made Kerouac an instant celebrity. While Kerouac traveled to Tangiers, San Francisco, and Mexico City, Johnson roamed the streets of the East Village, where she found herself in the midst of the cultural revolution the Beats had created. Minor Characters portrays the turbulent years of her relationship with Kerouac with extraordinary wit and love and a cool, critical eye, introducing the reader to a lesser known but purely original American voice: her own.

    She recounts the travails of growing up in a large, affluent family where there was a paucity of love and of basics such as food and clothing despite the presence of a chauffeur and a cook. She goes on to recount her early hospitalization for depression in poignant detail, as well as her complex relationship with her mercurial, withholding mother.Along the way Merkin also discusses her early, redemptive love of reading and gradual emergence as a writer. She eventually marries, has a child, and suffers severe postpartum depression, for which she is again hospitalized. Merkin also discusses her visits to various therapists and psychopharmocologists, which enables her to probe the causes of depression and its various treatments. The book ends in the present, where the writer has learned how to navigate her depression, if not “cure” it, after a third hospitalization in the wake of her mother’s death.

    Bejesus, isn't America a great and wonderful country?" His older brother Frank's Pulitzer Prize-winning memoir, Angela's Ashes, took its somber tone from the bleak atmosphere of those slums, while Malachy's boisterous recollections are fueled by his zestful appreciation for the opportunities and oddities of his native land. He and Frank were born in Brooklyn, moved with their parents to Ireland as children, then returned to the States as adults. This book covers the decade 1952-63, when Malachy roistered across the U.S., Europe, and Asia, but spent most of his time in New York City. There his ready wit and quick tongue won him an acting job with the Irish Players, a semiregular stint on The Tonight Show hosted by Jack Paar, and friendships with some well-heeled, well-born types who shared his fondness for saloon life and bankrolled him in an East Side saloon that may have been the first singles bar. He chronicles those events--and many others--with back-slapping bonhomie. Although McCourt acknowledges the personal demons that pursued him from his poverty-stricken childhood and destroyed his first marriage, this is on the whole an exuberant autobiography that pays tribute to the joys of a freewheeling life.

    A month later, none of that was true. Levy picks you up and hurls you through the story of how she built an unconventional life and then watched it fall apart with astonishing speed. Like much of her generation, she was raised to resist traditional rules—about work, about love, and about womanhood. “I wanted what we all want: everything. We want a mate who feels like family and a lover who is exotic, surprising. We want to be youthful adventurers and middle-aged mothers. We want intimacy and autonomy, safety and stimulation, reassurance and novelty, coziness and thrills. But we can’t have it all.” In this profound and beautiful memoir, Levy chronicles the adventure and heartbreak of being “a woman who is free to do whatever she chooses.” Her own story of resilience becomes an unforgettable portrait of the shifting forces in our culture, of what has changed—and of what is eternal.

    But beyond her massive professional success on the soccer field, Rapinoe has become an icon and ally to millions, boldly speaking out on the issues that matter most. In recent years, she's become one of the faces of the equal pay movement and her tireless activism for LGBTQ rights has earned her global support.In One Life, Rapinoe embarks on a thoughtful and unapologetic discussion of social justice and politics. Raised in a conservative small town in northern California, the youngest of six, Rapinoe was four years old when she kicked her first soccer ball. Her parents encouraged her love for the game, but also urged her to volunteer at homeless shelters and food banks. Her passion for community engagement never wavered through high school or college, all the way up to 2016, when she took a knee during the national anthem in solidarity with former NFL player Colin Kaepernick, to protest racial injustice and police brutality - the first high-profile white athlete to do so. The backlash was immediate, but it couldn't compare to the overwhelming support. Rapinoe became a force of social change, both on and off the field.Using anecdotes from her own life and career, from suing the United States Soccer Federation alongside her teammates over gender discrimination to her widely publicized refusal to visit the White House, Rapinoe discusses the obligation we all have to speak up, and reveals the impact each of us can have on our communities. As she declared during the soccer team's victory parade in New York in 2019, "[T]his is everybody's responsibility, every single person here, every single person who is not here, every single person who doesn't want to be here, every single person who agrees and doesn't agree.... It takes everybody. This is my charge to everybody. Do what you can. Do what you have to do. Step outside yourself. Be more. Be better. Be bigger than you've ever been before."