Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Larissa MacFarquhar digs deep into the psychological roots and existential dilemmas motivating those rare individuals practicing lives of extreme ethical commitment. The donor who offers up her kidney to a complete stranger; the activist who abandons possessions to devote himself to the cause; the foster parent who adopts dozens of children: such do-gooders inspire us but also force us to question deep-seated notions about what it means to be human. How could these do-gooders value strangers as much as their own loved ones? What does it really take to live a life of extreme virtue? Might it mean making choices as heartbreaking as the one in the old philosophy problem: abandoning a single family member to drown so that two strangers might live? Strangers Drowning combines real-life stories of unimaginable selflessness along with deep meditations on the shocking implications of these ethical acts.

    The Noble Hustle is Pulitzer finalist Colson Whitehead’s hilarious memoir of his search for meaning at high stakes poker tables, which the author describes as “Eat, Pray, Love for depressed shut-ins.”  On one level, The Noble Hustle is a familiar species of participatory journalism--a longtime neighborhood poker player, Whitehead was given a $10,000 stake and an assignment from the online online magazine Grantland to see how far he could get in the World Series of Poker.  But since it stems from the astonishing mind of Colson Whitehead (MacArthur Award-endorsed!), the book is a brilliant, hilarious, weirdly profound, and ultimately moving portrayal of--yes, it sounds overblown and ridiculous, but really!--the human condition.      After weeks of preparation that included repeated bus trips to glamorous Atlantic City, and hiring a personal trainer to toughen him up for sitting at twelve hours a stretch, the author journeyed to the gaudy wonderland that is Las Vegas – the world’s greatest “Leisure Industrial Complex” -- to try his luck in the multi-million dollar tournament.   Hobbled by his mediocre playing skills and a lifelong condition known as “anhedonia” (the inability to experience pleasure) Whitehead did not – spoiler alert!   - win tens of millions of dollars.  But he did chronicle his progress, both literal and existential, in this unbelievably funny, uncannily accurate social satire whose main target is the author himself.   Whether you’ve been playing cards your whole life, or have never picked up a hand, you’re sure to agree that this book contains some of the best writing about beef jerky ever put to paper.

    But as a new century approached, appetites broadened, and David Fairchild, a young botanist with an insatiable lust to explore and experience the world, set out in search of foods that would enrich the American farmer and enchant the American eater.Kale from Croatia, mangoes from India, and hops from Bavaria. Peaches from China, avocados from Chile, and pomegranates from Malta. Fairchild's finds weren't just limited to food: From Egypt he sent back a variety of cotton that revolutionized an industry, and via Japan he introduced the cherry blossom tree, forever brightening America's capital. Along the way, he was arrested, caught diseases, and bargained with island tribes. But his culinary ambition came during a formative era, and through him, America transformed into the most diverse food system ever created.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    Her deep empathy and understanding, her years of observing Kenya’s rich variety of wildlife, and her pioneering work in perfecting the right husbandry and milk formula have saved countless elephants, rhinos, and other baby animals from certain death. In this heartwarming and poignant memoir, Daphne shares her amazing relationships with a host of orphans, including her first love, Bushy, a liquid-eyed antelope; Rickey-Tickey-Tavey, the little dwarf mongoose; Gregory Peck, the busy buffalo weaver bird; Huppety, the mischievous zebra; and the majestic elephant Eleanor, with whom Daphne has shared more than forty years of great friendship.  But this is also a magical and heartbreaking human love story between Daphne and David Sheldrick, the famous Tsavo Park warden. It was their deep and passionate love, David’s extraordinary insight into all aspects of nature, and the tragedy of his early death that inspired Daphne’s vast array of achievements, most notably the founding of the world-renowned David Sheldrick Wildlife Trust and the Orphans’ Nursery in Nairobi National Park, where Daphne continues to live and work to this day.  Encompassing not only David and Daphne’s tireless campaign for an end to poaching and for conserving Kenya’s wildlife, but also their ability to engage with the human side of animals and their rearing of the orphans expressly so they can return to the wild, Love, Life, and Elephants is alive with compassion and humor, providing a rare insight into the life of one of the world’s most remarkable women.

    In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    The next anybody heard from her, this genteel, farm-reared, 67-year-old great-grandmother had walked 800 miles along the 2,050-mile Appalachian Trail. And in September 1955, having survived a rattlesnake strike, two hurricanes, and a run-in with gangsters from Harlem, she stood atop Maine’s Mount Katahdin. There she sang the first verse of “America, the Beautiful” and proclaimed, “I said I’ll do it, and I’ve done it.”Grandma Gatewood, as the reporters called her, became the first woman to hike the entire Appalachian Trail alone, as well as the first person—man or woman—to walk it twice and three times. Gatewood became a hiking celebrity and appeared on TV and in the pages of Sports Illustrated. The public attention she brought to the little-known footpath was unprecedented. Her vocal criticism of the lousy, difficult stretches led to bolstered maintenance, and very likely saved the trail from extinction.Author Ben Montgomery was given unprecedented access to Gatewood’s own diaries, trail journals, and correspondence, and interviewed surviving family members and those she met along her hike, all to answer the question so many asked: Why did she do it? The story of Grandma Gatewood will inspire readers of all ages by illustrating the full power of human spirit and determination. Even those who know of Gatewood don’t know the full story—a story of triumph from pain, rebellion from brutality, hope from suffering.

    You might even be worried that these lapses in memory could be an early sign of Alzheimer's or dementia. In reality, for the vast majority of us, these examples of forgetting are completely normal. Why? Because while memory is amazing, it is far from perfect. Our brains aren't designed to remember every name we hear, plan we make, or day we experience. Just because your memory sometimes fails doesn't mean it's broken or succumbing to disease. Forgetting is actually part of being human. In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car). And you'll see how memory is profoundly impacted by meaning, emotion, sleep, stress, and context. Once you understand the language of memory and how it functions, its incredible strengths and maddening weaknesses, its natural vulnerabilities and potential superpowers, you can both vastly improve your ability to remember and feel less rattled when you inevitably forget. You can set educated expectations for your memory, and in doing so, create a better relationship with it. You don't have to fear it anymore. And that can be life-changing.

    It enjoins us to see no stranger but instead look at others and say: You are part of me I do not yet know. Starting from that place of wonder, the world begins to change: It is a practice that can transform a relationship, a community, a culture, even a nation. Kaur takes readers through her own riveting journey—as a brown girl growing up in California farmland finding her place in the world; as a young adult galvanized by the murders of Sikhs after 9/11; as a law student fighting injustices in American prisons and on Guantánamo Bay; as an activist working with communities recovering from xenophobic attacks; and as a woman trying to heal from her own experiences with police violence and sexual assault. Drawing from the wisdom of sages, scientists, and activists, Kaur reclaims love as an active, public, and revolutionary force that creates new possibilities for ourselves, our communities, and our world. See No Stranger helps us imagine new ways of being with each other—and with ourselves—so that together we can begin to build the world we want to see.

    Each year they are seen by millions of visitors, and they have become as integral a part of the Tower as its ancient stones. But their role is even more important than that—legend has it that if the ravens should ever leave, the Tower will crumble into dust and great harm will befall the kingdom.The responsibility for ensuring that such a disaster never comes to pass falls to one man: the Ravenmaster. The current holder of the position is Yeoman Warder Christopher Skaife, and in this fascinating, entertaining and touching book he memorably describes the ravens’ formidable intelligence, their idiosyncrasies and their occasionally wicked sense of humour. The Ravenmaster is a compelling, inspiring and irreverent story that will delight and surprise anyone with an interest in British history or animal behaviour.

    She was married with children and a good career. So why did she feel miserable? And why did it seem that other Generation X women were miserable, too?Calhoun decided to find some answers. She looked into housing costs, HR trends, credit card debt averages, and divorce data. At every turn, she saw a pattern: sandwiched between the Boomers and the Millennials, Gen X women were facing new problems as they entered middle age, problems that were being largely overlooked.Speaking with women across America about their experiences as the generation raised to “have it all,” Calhoun found that most were exhausted, terrified about money, under-employed, and overwhelmed. Instead of being heard, they were told instead to lean in, take “me-time,” or make a chore chart to get their lives and homes in order.In Why We Can’t Sleep, Calhoun opens up the cultural and political contexts of Gen X’s predicament and offers solutions for how to pull oneself out of the abyss—and keep the next generation of women from falling in. The result is reassuring, empowering, and essential reading for all middle-aged women, and anyone who hopes to understand them.

    But under the surface was a wild instability. The only child of parents continually battling drug and alcohol addictions, Madden confronted her environment alone. Facing a culture of assault and objectification, she found lifelines in the desperately loving friendships of fatherless girls.With unflinching honesty and lyrical prose, spanning from 1960s Hawai'i to the present-day struggle of a young woman mourning the loss of a father while unearthing truths that reframe her reality, Long Live the Tribe of Fatherless Girls is equal parts eulogy and love letter. It's a story about trauma and forgiveness, about families of blood and affinity, both lost and found, unmade and rebuilt, crooked and beautiful.

    Kendi's concept of antiracism reenergizes and reshapes the conversation about racial justice in America--but even more fundamentally, points us toward liberating new ways of thinking about ourselves and each other. In How to be an Antiracist, Kendi asks us to think about what an antiracist society might look like, and how we can play an active role in building it. In this book, Kendi weaves together an electrifying combination of ethics, history, law, and science, bringing it all together with an engaging personal narrative of his own awakening to antiracism. How to Be an Antiracist is an essential work for anyone who wants to go beyond an awareness of racism to the next step: contributing to the formation of a truly just and equitable society.

    They ate braised leeks. They played by themselves while their parents sipped coffee. And yet French kids were still boisterous, curious, and creative. Why? How?            With a notebook stashed in her diaper bag, Druckerman set out to investigate—and wound up sparking a national debate on parenting. Researched over three years and written in her warm, funny voice, Bringing Up Bébé is deeply wise, charmingly told, and destined to become a classic resource for American parents.