In The Poisoner's Handbook Blum draws from highly original research to track the fascinating, perilous days when a pair of forensic scientists began their trailblazing chemical detective work, fighting to end an era when untraceable poisons offered an easy path to the perfect crime. Drama unfolds case by case as the heroes of The Poisoner's Handbook—chief medical examiner Charles Norris and toxicologist Alexander Gettler—investigate a family mysteriously stricken bald, Barnum and Bailey's Famous Blue Man, factory workers with crumbling bones, a diner serving poisoned pies, and many others. Each case presents a deadly new puzzle and Norris and Gettler work with a creativity that rivals that of the most imaginative murderer, creating revolutionary experiments to tease out even the wiliest compounds from human tissue. Yet in the tricky game of toxins, even science can't always be trusted, as proven when one of Gettler's experiments erroneously sets free a suburban housewife later nicknamed "America's Lucretia Borgia" to continue her nefarious work. From the vantage of Norris and Gettler's laboratory in the infamous Bellevue Hospital it becomes clear that killers aren't the only toxic threat to New Yorkers. Modern life has created a kind of poison playground, and danger lurks around every corner. Automobiles choke the city streets with carbon monoxide; potent compounds, such as morphine, can be found on store shelves in products ranging from pesticides to cosmetics. Prohibition incites a chemist's war between bootleggers and government chemists while in Gotham's crowded speakeasies each round of cocktails becomes a game of Russian roulette. Norris and Gettler triumph over seemingly unbeatable odds to become the pioneers of forensic chemistry and the gatekeepers of justice during a remarkably deadly time. A beguiling concoction that is equal parts true crime, twentieth-century history, and science thriller, The Poisoner's Handbook is a page-turning account of a forgotten New York.

    But, after a broken engagement and a broken heart, he desperately needed a change of scenery. The ambitious plan he cooked up went a bit overboard in that department; Knighton set out to visit every single one of America's National Parks, from Acadia to Zion. Leave Only Footprints is the memoir of his year spent traveling across the United States, a journey that yielded his "On the Trail" series, which quickly became one of CBS Sunday Morning's most beloved segments. In this smart, informative, and often hilarious book, he'll share how his journey through these natural wonders, unchanged by man, ended up changing his worldview on everything from God to politics to love and technology. Whether it's waking up early for a naked scrub in an Arkansas bathhouse or staying up late to stargaze along our loneliest highway, Knighton goes behind the scenery to provide an unfiltered look at America. In the tradition of books like A Walk in the Woods or Turn Right at Machu Picchu, this is an irresistible mix of personal narrative and travelogue-some well-placed pop culture references, too-and a must-read for any of the 331 million yearly National Parks visitors.

    This is the funny, poignant story of their two decades together.On Valentine's Day 1985, biologist Stacey O'Brien first met a four-day-old baby barn owl -- a fateful encounter that would turn into an astonishing 19-year saga. With nerve damage in one wing, the owlet's ability to fly was forever compromised, and he had no hope of surviving on his own in the wild. O'Brien, a young assistant in the owl laboratory at Caltech, was immediately smitten, promising to care for the helpless owlet and give him a permanent home. Wesley the Owl is the funny, poignant story of their dramatic two decades together. With both a tender heart and a scientist's eye, O'Brien studied Wesley's strange habits intensively and first-hand -- and provided a mice-only diet that required her to buy the rodents in bulk (28,000 over the owl's lifetime). As Wesley grew, she snapped photos of him at every stage like any proud parent, recording his life from a helpless ball of fuzz to a playful, clumsy adolescent to a gorgeous, gold-and-white, macho adult owl with a heart-shaped face and an outsize personality that belied his 18-inch stature. Stacey and Wesley's bond deepened as she discovered Wesley's individual personality, subtle emotions, and playful nature that could also turn fiercely loyal and protective -- though she could have done without Wesley's driving away her would-be human suitors! O'Brien also brings us inside the prestigious research community, a kind of scientific Hogwarts where resident owls sometimes flew freely from office to office and eccentric, brilliant scientists were extraordinarily committed to studying and helping animals; all of them were changed by the animal they loved. As O'Brien gets close to Wesley, she makes important discoveries about owl behavior, intelligence, and communication, coining the term "The Way of the Owl" to describe his inclinations: he did not tolerate lies, held her to her promises, and provided unconditional love, though he was not beyond an occasional sulk. When O'Brien develops her own life-threatening illness, the biologist who saved the life of a helpless baby bird is herself rescued from death by the insistent love and courage of this wild animal. Enhanced by wonderful photos, Wesley the Owl is a thoroughly engaging, heartwarming, often funny story of a complex, emotional, non-human being capable of reason, play, and, most important, love and loyalty. It is sure to be cherished by animal lovers everywhere.

    Indians armed with poison-tipped arrows haunt its shadows; piranhas glide through its waters; boulder-strewn rapids turn the river into a roiling cauldron.After his humiliating election defeat in 1912, Roosevelt set his sights on the most punishing physical challenge he could find, the first descent of an unmapped, rapids-choked tributary of the Amazon. Together with his son Kermit and Brazil’s most famous explorer, Cândido Mariano da Silva Rondon, Roosevelt accomplished a feat so great that many at the time refused to believe it. In the process, he changed the map of the western hemisphere forever.Along the way, Roosevelt and his men faced an unbelievable series of hardships, losing their canoes and supplies to punishing whitewater rapids, and enduring starvation, Indian attack, disease, drowning, and a murder within their own ranks. Three men died, and Roosevelt was brought to the brink of suicide. The River of Doubt brings alive these extraordinary events in a powerful nonfiction narrative thriller that happens to feature one of the most famous Americans who ever lived.From the soaring beauty of the Amazon rain forest to the darkest night of Theodore Roosevelt’s life, here is Candice Millard’s dazzling debut.

    The weird turns that followed in this already sensational take are truly astonishing--the Hearst family tried to secure Patty's release by feeding the people of Oakland and San Francisco for free; bank security cameras captured "Tania" wielding a machine gun during a roberry; the LAPD engaged in the largest police shoot-out in American history; the first breaking news event was broadcast live on telelvision stations across the country; and then there was Patty's circuslike trial, filled with theatrical courtroom confrontations and a dramatic last-minute reversal, after which the term "Stockholm syndrome" entered the lexicon. Ultimately, the saga highlighted a decade in which America seemed to be suffering a collective nervous breakdown.

    In a lab filled with curiosities--beakers, microscopes, Bunsen burners, and hundreds upon hundreds of books--sat an investigator who would go on to crack at least two thousand cases in his forty-year career. Known as the "American Sherlock Holmes," Edward Oscar Heinrich was one of America's greatest--and first--forensic scientists, with an uncanny knack for finding clues, establishing evidence, and deducing answers with a skill that seemed almost supernatural.Heinrich was one of the nation's first expert witnesses, working in a time when the turmoil of Prohibition led to sensationalized crime reporting and only a small, systematic study of evidence. However with his brilliance, and commanding presence in both the courtroom and at crime scenes, Heinrich spearheaded the invention of a myriad of new forensic tools that police still use today, including blood spatter analysis, ballistics, lie-detector tests, and the use of fingerprints as courtroom evidence. His work, though not without its serious--some would say fatal--flaws, changed the course of American criminal investigation.Based on years of research and thousands of never-before-published primary source materials, American Sherlock captures the life of the man who pioneered the science our legal system now relies upon--as well as the limits of those techniques and the very human experts who wield them.

    These “psychosurgeons,” as they called themselves, occupied a gray zone between medical research and medical practice, and ended up subjecting untold numbers of people to the types of surgical experiments once limited to chimpanzees.The most important test subject to emerge from this largely untold chapter in American history was a twenty-seven-year-old factory worker named Henry Molaison. In 1953, Henry—who suffered from severe epilepsy—received a radical new version of the lobotomy, one that targeted the most mysterious structures in the brain. The operation failed to eliminate Henry’s seizures, but it did have an unintended effect: Henry left the operating room profoundly amnesic, unable to create new long-term memories. Over the next sixty years, Patient H.M., as Henry was known, became the most studied individual in the history of neuroscience, a human guinea pig who would teach us much of what we know about memory today.Luke Dittrich uses the case of Patient H.M. as a starting point for a kaleidoscopic journey, one that moves from the first recorded brain surgeries in ancient Egypt to the cutting-edge laboratories of MIT. He takes readers inside the old asylums and operating theaters where psychosurgeons conducted their human experiments, and behind the scenes of a bitter custody battle over the ownership of the most important brain in the world. Throughout, Dittrich delves into the enduring mysteries of the mind while exposing troubling stories of just how far we’ve gone in our pursuit of knowledge. It is also, at times, a deeply personal journey. Dittrich’s grandfather was the brilliant, morally complex surgeon who operated on Molaison—and thousands of other patients. The author’s investigation into the dark roots of modern memory science ultimately forces him to confront unsettling secrets in his own family history, and to reveal the tragedy that fueled his grandfather’s relentless experimentation—experimentation that would revolutionize our understanding of ourselves.Patient H.M. combines the best of biography, memoir, and science journalism to create a haunting, endlessly fascinating story, one that reveals the wondrous and devastating things that can happen when hubris, ambition, and human imperfection collide.

    Into the rarefied atmosphere of wealth and tradition comes the most unlikely of horses—a drab white former plow horse named Snowman—and his rider, Harry de Leyer. They were the longest of all longshots—and their win was the stuff of legend. Harry de Leyer first saw the horse he would name Snowman on a bleak winter afternoon between the slats of a rickety truck bound for the slaughterhouse. He recognized the spark in the eye of the beaten-up horse and bought him for eighty dollars. On Harry’s modest farm on Long Island, the horse thrived. But the recent Dutch immigrant and his growing family needed money, and Harry was always on the lookout for the perfect thoroughbred to train for the show-jumping circuit—so he reluctantly sold Snowman to a farm a few miles down the road. But Snowman had other ideas about what Harry needed. When he turned up back at Harry’s barn, dragging an old tire and a broken fence board, Harry knew that he had misjudged the horse. And so he set about teaching this shaggy, easygoing horse how to fly. One show at a time, against extraordinary odds and some of the most expensive thoroughbreds alive, the pair climbed to the very top of the sport of show jumping. Here is the dramatic and inspiring rise to stardom of an unlikely duo, based on the insight and recollections of “the Flying Dutchman” himself. Their story captured the heart of Cold War–era America—a story of unstoppable hope, inconceivable dreams, and the chance to have it all. Elizabeth Letts’s message is simple: Never give up, even when the obstacles seem sky-high. There is something extraordinary in all of us.

    Helens in southwestern Washington State. Still, no one was prepared when a cataclysmic eruption blew the top off of the mountain, laying waste to hundreds of square miles of land and killing fifty-seven people. Steve Olson interweaves vivid personal stories with the history, science, and economic forces that influenced the fates and futures of those around the volcano. Eruption delivers a spellbinding narrative of an event that changed the course of volcanic science, and an epic tale of our fraught relationship with the natural world.

    Delving into brand-new research, she uncovers the powers of the natural world to improve health, promote reflection and innovation, and strengthen our relationships. As our modern lives shift dramatically indoors, these ideas—and the answers they yield—are more urgent than ever.

    A rogue black bear, 300 pounds of fury, is attacking the family's campsite, pouncing on her parents as prey.At her dying mother's faint urging, Anna manages to get her brother into the family's canoe and paddle away. But when the canoe dumps the two children on the edge of the woods, and the sister and brother must battle hunger, the elements, and a dangerous wilderness, we see Anna's heartbreaking love for her family -- and her struggle to be brave when nothing in her world seems safe anymore.Told in the honest, raw voice of five-year-old Anna, this is a riveting story of love, courage, and survival.

    A sexual sadist who taunted police with anonymous notes. A madman who was never apprehended. This is the first, complete account of Zodiac's reign of terror. Is he still out there?

    “The days are long, but the years are short,” she realized. “Time is passing, and I’m not focusing enough on the things that really matter.” In that moment, she decided to dedicate a year to her happiness project.In this lively and compelling account, Rubin chronicles her adventures during the twelve months she spent test-driving the wisdom of the ages, current scientific research, and lessons from popular culture about how to be happier. Among other things, she found that novelty and challenge are powerful sources of happiness; that money can help buy happiness, when spent wisely; that outer order contributes to inner calm; and that the very smallest of changes can make the biggest difference.