In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.

    Steven Hatch first came to Liberia in November 2013, to work at a hospital in Monrovia. Six months later, several of the physicians Dr. Hatch had mentored and served with were dead or barely clinging to life, and Ebola had become a world health emergency. Hundreds of victims perished each week; whole families were destroyed in a matter of days; so many died so quickly that the culturally taboo practice of cremation had to be instituted to dispose of the bodies. With little help from the international community and a population ravaged by disease and fear, the war-torn African nation was simply unprepared to deal with the catastrophe.A physician’s memoir about the ravages of a terrible disease and the small hospital that fought to contain it, Inferno is also an explanation of the science and biology of Ebola: how it is transmitted and spreads with such ferocity. And as Dr. Hatch notes, while Ebola is temporarily under control, it will inevitably re-emerge—as will other plagues, notably the Zika virus, which the World Health Organization has declared a public health emergency. Inferno is a glimpse into the white-hot center of a crisis that will come again.

    In addition to offering a clear-eyed explanation of the root causes of this insidious and entrenched bias and laying out its effects, she suggests concrete steps we can take to cure it.

    This distinctive text was developed to stand apart from all other A&P texts with unparalleled art, a writing style that has been acclaimed by both users and reviewers and clinical coverage that offers the perfect balance without being too much. Saladin's well-accepted organization of topics is based upon the most logical physiological ties between body systems. This text requires no prior knowledge of college chemistry or cell biology, and is designed for a two-semester A&P college course.

    gross domestic product by 2020. In Drugs for Life, Joseph Dumit considers how our burgeoning consumption of medicine and cost of healthcare not only came to be, but also came to be taken for granted. For several years, Dumit attended pharmaceutical industry conferences; spoke with marketers, researchers, doctors, and patients; and surveyed the industry's literature regarding strategies to expand markets for prescription drugs. He concluded that underlying the continual growth in medications, disease categories, costs, and insecurity is a relatively new perception of ourselves as inherently ill and in need of chronic treatment. This perception is based on clinical trials that we have largely outsourced to pharmaceutical companies. Those companies in turn see clinical trials as investments and measure the value of those investments by the size of the market and profits that they will create. They only ask questions for which the answer is more medicine. Drugs for Life challenges our understanding of health, risks, facts, and clinical trials, the very concepts used by pharmaceutical companies to grow markets to the point where almost no one can imagine a life without prescription drugs.

    Touch it and you die. Every politician knows this truism, which is why no one wants to debate it. Privately, many of them understand that the health care system, which costs about $200 billion a year in public and private money, cannot continue as it is—increasingly ill-adapted to an aging population with public costs growing faster than government revenues. In Chronic Condition, Jeffrey Simpson meets health care head on and explores the only four options we have to end this growing crisis: cuts in spending, tax increases, privatization, and reaping savings through increased efficiency. He examines the tenets of the Medicare system that Canadians cling to so passionately. Here, he finds that many other countries have more extensive public health systems, and Canadian health care produces only average value for money. In fact, our rigid system for some health care needs and a costly system for other needs—drugs, dentistry, and home care—is really the worst of both worlds. Chronic Condition breaks the silence about the huge changes and real choices that Canadians face.

    Stress is the great killer of modern life. Ancient Eastern mind-body techniques can bring us balance and healing. We’ve all heard claims like these, and many find them plausible. When it comes to disease and healing, we believe we must look beyond doctors and drugs; we must look within ourselves. Faith, relationships, and attitude matter.But why do we believe such things? From psychoanalysis to the placebo effect to meditation, this vibrant history describes our commitments to mind-body healing as rooted in a patchwork of stories that have allowed people to make new sense of their suffering, express discontent with existing care, and rationalize new treatments and lifestyles. These stories are sometimes supported by science, sometimes quarrel with science, but are all ultimately about much more than just science.

    Symptoms run from mild lethargy to severe arthritis to incapacitating mental dysfunction. And despite medical pronouncements to the contrary, extensive research has found that tests for the disease are not very reliable and antibiotics are only partially effective; up to 35 percent of those infected will not respond to treatment or will relapse. The spirochetes that cause Lyme are stealth pathogens--they can hide within cells or alter their form so that antibiotics cannot affect them. Lyme disease is, in fact, a potent, emerging epidemic disease for which technological medicine is only partially effective.Healing Lyme examines the leading, scientific research on Lyme infection, its tests and treatments, and outlines the most potent herbal medicines and supplements that offer help--either alone or in combination with antibiotics--for preventing and healing the disease. It is the essential guide to Lyme infection and its treatment.

    This enormously popular book — the best and most authoritative resource for unbiased information about how drugs affect the mind and the body — covers a wide range of available substances, from coffee to marijuana, antihistamines to psychedelics, steroids to smart drugs, and discusses likely effects, precautions, and alternatives. Now expanded and updated to cover such drugs as oxycontin, Ecstasy, Prozac, and ephedra and to address numerous ongoing issues, including the United States’ war on drugs, marijuana for therapeutic use, the overuse of drugs for children diagnosed with ADHD, and more, From Chocolate to Morphine is an invaluable resource.

    But its roots stretch back as far as ancient Greece, when medicine first departed from the divine and the mystical and moved toward observation and logic. Its early development was slow, constrained by the taboo around dissection (only external symptoms could be used for diagnosis), as well as superstition and mysticism (illness was the work of demons and pixies and curable only by penitence). Paul Strathern steers us skillfully through the maze of discoveries, diseases, and wrong turns that have made medicine what it is today—super efficient, high tech, and increasingly costly. A Brief History of Medicine offers an accessible history of the arguments, missteps, and dumb luck that led to the world's most important medical breakthroughs—from anatomy, grave robbing, the plague, and germ theory to vaccination, quackery, microorganisms, and penicillin.

    Now known mostly as a disease of the tropics, malaria led to the demise of the Roman Empire 2,000 years ago and ravaged Europe for years afterwards. At the start of the 17th century, Jesuit priests developed quinine, an alkaloid made out of the bitter red bark of the cinchona tree from the Andes. When quinine arrived in Europe, the Protestant powers resisted the medicine fearing that it was a Popish poison. Quinine’s reputation improved, however, when King Charles II was cured of malaria through its offices. Through the centuries, wars were fought to control the supply-through the building of the Panama Canal and into WWII--until Americans synthesized quinine for the first time in 1944.Rocco describes the ravages of the disease, the search for a cure, and the quest to steal and smuggle cinchona seeds out of South America. The Miraculous Fever Tree deftly illuminates the religious and scientific rivalries, intrepid exploration and colonization evinced by the search for quinine.

    Barbara Ravage has fashioned an enlightening, invaluable book.” —Stewart O’Nan, author of The Circus Fire: A True Story of an American TragedyThough each of us is just a spark away from being a burn victim, the public knows little and understands less about the world that patients inhabit. Pulling the curtains back on this private and sterile environment, Burn Unit is a riveting account of the frontline efforts—both modern-day and historical—to save lives devastated by fire. With unflinching urgency, Barbara Ravage follows an extraordinary team of healers at Massachusetts General Hospital, the cradle of modern burn treatment and the site of one of the best burn units in the world. From Boston’s Cocoanut Grove fire of 1942 to the treatment of the victims of the Rhode Island nightclub fire in early 2003, we watch everyday heroes do their incredible but punishing work against the backdrop of history. Both a moving human drama and an engrossing scientific exploration of this little-known field of medicine, Burn Unit is an unforgettably powerful read.

    Long-established techniques are carefully explained as well as exciting new methods as the authors describe the ways in which archaeologists seek to explain and interpret the remote past of humankind

    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

    Often they seem aloof, uncaring, and hurried. Of course, they’re not all like that, and most didn’t start out that way. Here are voices of third-year students just as they begin to take on clinical responsibilities. Their words focus on the odd transition students face when they must deal with real people in real time and in real crises and when they must learn to put aside their emotions to make quick, accurate, and sensitive decisions. Their decisions aren’t always right, and the consequences can be life-altering—for all involved. Moving, disturbing, and candid, their true stories show us a side of the profession that few ever see, or could even imagine. They show, often painfully, how medical students grow up, right at the bedside.