But as early as August 2015, doctors in northeast Brazil began to notice a trend: many mothers who had recently experienced symptoms of the Zika virus were giving birth to babies with microcephaly, a serious disorder characterized by unusually small heads and brain damage.By early 2016, Zika was making headlines as evidence mounted—and eventually confirmed—that microcephaly is caused by the virus, which can be contracted through mosquito bites or sexually transmitted.The first death on American soil, in February 2016, was confirmed in Puerto Rico in April. The first case of microcephaly in Puerto Rico was confirmed on May 13, 2016. The virus has been known to be transmitted by the Aedes aegypti or Yellow Fever mosquito, but now Aedes albopictus, the Asian Tiger mosquito, has been found to carry it as well, which means it might affect regions as far north as New England and the Great Lakes. Right now, at least 298 million people in the Americas live in areas “conducive to Zika transmission,” according to a recent study. Over the next year, more than 5 million babies will be born.In Zika: The Emerging Epidemic, Donald G. McNeil Jr. sets the facts straight in a fascinating exploration of Zika’s origins, how it’s spreading, the race for a cure, and what we can do to protect ourselves now.

    Brenda Maddox tells a powerful story of a remarkably single-minded, forthright, and tempestuous young woman who, at the age of fifteen, decided she was going to be a scientist, but who was airbrushed out of the greatest scientific discovery of the twentieth century.

    Then he disappeared, eluding capture by multiple police forces and some of the best detectives in the area.Three decades later, Michelle McNamara, a true crime journalist who created the popular website TrueCrimeDiary.com, was determined to find the violent psychopath she called "the Golden State Killer." Michelle pored over police reports, interviewed victims, and embedded herself in the online communities that were as obsessed with the case as she was.At the time of the crimes, the Golden State Killer was between the ages of eighteen and thirty, Caucasian, and athletic—capable of vaulting tall fences. He always wore a mask. After choosing a victim—he favored suburban couples—he often entered their home when no one was there, studying family pictures, mastering the layout. He attacked while they slept, using a flashlight to awaken and blind them. Though they could not recognize him, his victims recalled his voice: a guttural whisper through clenched teeth, abrupt and threatening.I’ll Be Gone in the Dark—the masterpiece McNamara was writing at the time of her sudden death—offers an atmospheric snapshot of a moment in American history and a chilling account of a criminal mastermind and the wreckage he left behind. It is also a portrait of a woman’s obsession and her unflagging pursuit of the truth. Framed by an introduction by Gillian Flynn and an afterword by her husband, Patton Oswalt, the book was completed by Michelle’s lead researcher and a close colleague. Utterly original and compelling, it is destined to become a true crime classic—and may at last unmask the Golden State Killer.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    Her first book is a revelatory treatise on plant life—but it is also so much more. Lab Girl is a book about work, love, and the mountains that can be moved when those two things come together. It is told through Jahren’s stories: about her childhood in rural Minnesota with an uncompromising mother and a father who encouraged hours of play in his classroom’s labs; about how she found a sanctuary in science, and learned to perform lab work done “with both the heart and the hands”; and about the inevitable disappointments, but also the triumphs and exhilarating discoveries, of scientific work.Yet at the core of this book is the story of a relationship Jahren forged with a brilliant, wounded man named Bill, who becomes her lab partner and best friend. Their sometimes rogue adventures in science take them from the Midwest across the United States and back again, over the Atlantic to the ever-light skies of the North Pole and to tropical Hawaii, where she and her lab currently make their home.

    Forty-five million called him emperor, and he commanded a nation that was the richest, most cultured, and advanced on earth. No army could stand against his impeccably trained, brilliantly led forces, and his continued sweep across Europe seemed inevitable. Early that year, bolstered by his successes, Napoleon turned his attentions toward Moscow, helming the largest invasion in human history. Surely, Tsar Alexander’s outnumbered troops would crumble against this mighty force. But another powerful and ancient enemy awaited Napoleon’s men in the Russian steppes. Virulent and swift, this microscopic foe would bring the emperor to his knees. Even as the Russians retreated before him in disarray, Napoleon found his army disappearing, his frantic doctors powerless to explain what had struck down a hundred thousand soldiers. The emperor’s vaunted military brilliance suddenly seemed useless, and when the Russians put their own occupied capital to the torch, the campaign became a desperate race through the frozen landscape as troops continued to die by the thousands. Through it all, with tragic heroism, Napoleon’s disease-ravaged, freezing, starving men somehow rallied, again and again, to cries of “Vive l’Empereur!”Yet Talty’s sweeping tale takes us far beyond the doomed heroics and bloody clashes of the battlefield. The Illustrious Dead delves deep into the origins of the pathogen that finally ended the mighty emperor’s dreams of world conquest and exposes this “war plague’s” hidden role throughout history. A tale of two unstoppable forces meeting on the road to Moscow in an epic clash of killer microbe and peerless army, The Illustrious Dead is a historical whodunit in which a million lives hang in the balance.

    Jacobs tackles his most challenging experiment yet: a yearlong mission to radically improve every element of his body and mind—from his brain to his fingertips to his abs.From the bestselling author of The Year of Living Biblically and The Know-It-All comes the true and truly hilarious story of one person’s quest to become the healthiest man in the world. Hospitalized with a freak case of tropical pneumonia, goaded by his wife telling him, “I don’t want to be a widow at forty-five,” and ashamed of a middle-aged body best described as “a python that swallowed a goat,” A.J. Jacobs felt compelled to change his ways and get healthy. And he didn’t want only to lose weight, or finish a triathlon, or lower his cholesterol. His ambitions were far greater: maximal health from head to toe. The task was epic. He consulted an army of experts— sleep consultants and sex clinicians, nutritionists and dermatologists. He subjected himself to dozens of different workouts—from Strollercize classes to Finger Fitness sessions, from bouldering with cavemen to a treadmill desk. And he took in a cartload of diets: raw foods, veganism, high protein, calorie restriction, extreme chewing, and dozens more. He bought gadgets and helmets, earphones and juicers. He poked and he pinched. He counted and he measured. The story of his transformation is not only brilliantly entertaining, but it just may be the healthiest book ever written. It will make you laugh until your sides split and endorphins flood your bloodstream. It will alter the contours of your brain, imprinting you with better habits of hygiene and diet. It will move you emotionally and get you moving physically in surprising ways. And it will give you occasion to reflect on the body’s many mysteries and the ultimate pursuit of health: a well-lived life.

    Shantaram is narrated by Lin, an escaped convict with a false passport who flees maximum security prison in Australia for the teeming streets of a city where he can disappear.Accompanied by his guide and faithful friend, Prabaker, the two enter Bombay's hidden society of beggars and gangsters, prostitutes and holy men, soldiers and actors, and Indians and exiles from other countries, who seek in this remarkable place what they cannot find elsewhere.As a hunted man without a home, family, or identity, Lin searches for love and meaning while running a clinic in one of the city's poorest slums, and serving his apprenticeship in the dark arts of the Bombay mafia. The search leads him to war, prison torture, murder, and a series of enigmatic and bloody betrayals. The keys to unlock the mysteries and intrigues that bind Lin are held by two people. The first is Khader Khan: mafia godfather, criminal-philosopher-saint, and mentor to Lin in the underworld of the Golden City. The second is Karla: elusive, dangerous, and beautiful, whose passions are driven by secrets that torment her and yet give her a terrible power.Burning slums and five-star hotels, romantic love and prison agonies, criminal wars and Bollywood films, spiritual gurus and mujaheddin guerrillas—this huge novel has the world of human experience in its reach, and a passionate love for India at its heart. Based on the life of the author, it is by any measure the debut of an extraordinary voice in literature.

    When she opened it, an FBI agent informed her that her father had been arrested for murdering ten people, including two children. It was then that she learned her father was the notorious serial killer known as BTK, a name he’d given himself that described the horrific way he committed his crimes: bind, torture, kill. As news of his capture spread, Wichita celebrated the end of a thirty-one-year nightmare. For Kerri Rawson, another was just beginning. She was plunged into a black hole of horror and disbelief. The same man who had been a loving father, a devoted husband, church president, Boy Scout leader, and a public servant had been using their family as a cover for his heinous crimes since before she was born. Everything she had believed about her life had been a lie.Written with candor and extraordinary courage, A Serial Killer’s Daughter is an unflinching exploration of life with one of America’s most infamous killers and an astonishing tale of personal and spiritual transformation. For all who suffer from unhealed wounds or the crippling effects of violence, betrayal, and anger, Kerri Rawson’s story offers the hope of reclaiming sanity in the midst of madness, rebuilding a life in the shadow of death, and learning to forgive the unforgivable.

    Completely overwhelmed and wrapped in stifling protective suits, he and his team took it in turns to provide care to patients while removing dead bodies from the ward. Against all odds he battled to keep the hospital open, as the queue of sick and dying patients grew every day. Only a few miles down the road the Irish Ambassador and Head of Irish Aid worked relentlessly to rapidly scale up the international response. At a time when entire districts had been quarantined, she travelled around the country, and met with UN agencies, the President and senior ministers so as to be better placed in alerting the world to the catastrophe unfolding in front of her.In this blow-by-blow account, Walsh and Johnson expose the often shocking shortcomings of the humanitarian response to the outbreak, both locally and internationally, and call our attention to the immense courage of those who put their lives on the line every day to contain the disease. Theirs is the definitive account of the fight against an epidemic that shook the world.

    Recounts stories from her vast case files that are alternately terrifying, tragically comic, and profoundly moving, all while she deals with her best friend and fellow doctor's fight with cancer.

    That was eight months ago.Richard now has ALS, and his entire right arm is paralyzed. His fingers are impotent, still, devoid of possibility. The loss of his hand feels like a death, a loss of true love, a divorce—his divorce.He knows his left arm will go next.Three years ago, Karina removed their framed wedding picture from the living room wall and hung a mirror there instead. But she still hasn’t moved on. Karina is paralyzed by excuses and fear, stuck in an unfulfilling life as a piano teacher, afraid to pursue the path she abandoned as a young woman, blaming Richard and their failed marriage for all of it.When Richard becomes increasingly paralyzed and is no longer able to live on his own, Karina becomes his reluctant caretaker. As Richard’s muscles, voice, and breath fade, both he and Karina try to reconcile their past before it’s too late.

    Period. is an agenda-setting manifesto to remove the stigma and myths continuing to surround the female body. Bold and unapologetic, Emma Barnett is on a crusade to ignite conversation among women--and men--everywhere.

    I was mentally and physically broken. So fractured, I hadn't eaten properly or slept well, or even changed my expression for months. I sat in a cubicle, behind paper-thin curtains, listening to the rest of the hospital happen around me, and I shook with the effort of not crying. I was an inch away from defeat, from the acceptance of a failure I assumed would be inevitable, but I knew I had to carry on. I had to somehow walk through it.Because I wasn't the patient. I was the doctor."A frank account of mental health from both sides of the doctor-patient divide, from the bestselling author of The Trouble with Goats and Sheep and Three Things About Elsie, based on her own experience as a doctor working on a psychiatric ward.

    He's a man on a mission to save the world's most endangered plants from destruction and thieves hunting for wealthy collectors. He is a plant messiah.From the planet's tiniest waterlily - the Nymphaea thermarum - to Huarango trees with roots over 50 metres long, Carlos has a miraculous ability to bring breathtakingly beautiful plants back from the brink of extinction. He has travelled to the most remote and dangerous parts of the world - from the mountains of Peru to isolated Indian Ocean islands to the deepest Australian outback - in search of the rarest exotic species. Then, back in the Tropical Nursery at Kew, he uses pioneering, left-field techniques to help them grow.Now he's here to spread the gospel. The Plant Messiah is the inspirational story of a man who has devoted - and risked - his life to save incredible species, all in the name of making this Earth a greener and happier place. Amen to that.