Comparing gene sequences, examining atomic structures of proteins, and looking into the geochemistry of rocks have helped explain evolution in more detail than ever before. Nick Lane expertly reconstructs the history of life by describing the ten greatest inventions of evolution (including DNA, photosynthesis, sex, and sight), based on their historical impact, role in organisms today, and relevance to current controversies. Who would have guessed that eyes started off as light-sensitive spots used to calibrate photosynthesis in algae? Or that DNA’s building blocks form spontaneously in hydrothermal vents? Lane gives a gripping, lucid account of nature’s ingenuity, and the result is a work of essential reading for anyone who has ever pondered or questioned the science underlying evolution’s greatest gifts to man.

    As recently as 1918, a pandemic of influenza claimed over 50 million lives worldwide. The advent of drugs and vaccines led to an era of hope when we thought our battles with infectious disease were won, but our optimism has been eroded by the recognition that many pathogens have the capacity to transform themselves and escape our efforts to eradicate them. Are we now facing an inevitable repeat of a calamity such as the 1918 influenza pandemic or the Black Death? Can we anticipate and thwart such an event, or are we wilfully creating the conditions that would promote the emergence of new and highly virulent human infectious disease?Sunetra Gupta is Professor of Theoretical Epidemiology at the University of Oxford specialising in infectious diseases. She holds a bachelor's degree from Princeton University and a Ph.D. from the University of London. She has been awarded the Scientific Medal by the Zoological Society of London and the Royal Society Rosalind Franklin Award for her scientific research. She is also a novelist whose books have been awarded the Sahitya Akademi Award, the Southern Arts Literature Prize, shortlisted for the Crossword Award, and longlisted for the DSC and Orange Prizes.

    But ever wonder who's pulling their strings? Who the movers and shakers are around the globe? In sharp, witty prose, What Every American Should Know About Who's Really Running the World spells out exactly who to watch and what they've done (and are still doing).Get the lowdown on:- Pfizer - Monsanto - Oprah Winfrey - WTO & IMF - Wal-Mart - Rupert Murdoch - Al Qaeda Filled with hard facts, global issues, and profiles of the heavy hitters, What Every American Should Know About Who's Really Running the World is essential reading for all Americans who want a handle on the movers and shakers behind the headlines.

    It is the story of the men who built the transcontinental railroad—the investors who risked their businesses and money; the enlightened politicians who understood its importance; the engineers and surveyors who risked, and sometimes lost, their lives; and the Irish and Chinese immigrants, the defeated Confederate soldiers, and the other laborers who did the backbreaking and dangerous work on the tracks.The U.S. government pitted two companies—the Union Pacific and the Central Pacific Railroads—against each other in a race for funding, encouraging speed over caution. Locomotives, rails, and spikes were shipped from the East through Panama or around South America to the West or lugged across the country to the Plains. In Ambrose's hands, this enterprise, with its huge expenditure of brainpower, muscle, and sweat, comes vibrantly to life.

    Our health care is staggeringly expensive, yet one in six Americans has no health insurance. We have some of the most skilled physicians in the world, yet one hundred thousand patients die each year from medical errors. In this gripping, eye-opening book, award-winning journalist Shannon Brownlee takes readers inside the hospital to dismantle some of our most venerated myths about American medicine. Using vivid examples of real patients and physicians, Overtreated debunks the idea that most of medicine is based in sound science, and shows how our health care system delivers huge amounts of unnecessary care that is not only expensive and wasteful but can actually imperil the health of patients.The interests of politicians and the medical-industrial complex continually trump those of patients, seducing the wealthy with unnecessary procedures and leaving the poor with haphazard access to treatment. Backward economic incentives allow patients with chronic conditions to receive ineffective care, and roll after roll of red tape undermines even the best-intentioned doctors. Tens of thousands of patients die each year from overtreatment. American medicine is in desperate need of fixing.Nevertheless, Overtreated ultimately conveys a message of hope by reframing the debate over health care reform. Americans worry about rationing--that any effort to rein in the high cost of health care will result in limited access to life-saving treatments. Covering the uninsured seems like an insurmountable problem because it will drive up costs even more. Overtreated offers a way to control costs and cover the uninsured, while simultaneously improving the quality of American medicine. Shannon Brownlee's humane, intelligent, and penetrating analysis empowers readers to avoid the perils of overtreatment, as well as pointing the way to better health care for everyone.

    Linnea Smith went to Peru on an ecotourism vacation. She was so moved that she abandoned her thriving medical practice in Wisconsin to serve the Yagua Indians in the deepest part of the Amazon rainforest of Peru-alone.Taken straight from the pages of Dr. Smith’s journal, La Doctora offers readers a rare glimpse into the suspense and drama of practicing medicine in a culture far removed from the sophisticated supplies and supports of 20th-century medicine.Learn how Dr. Smith evolved from a “strange white woman” to an adopted member of the indigenous community. Her story of adventure, self-discovery and service creates inspiring testimony to one person’s power to make a lasting difference.

    1' is an intimate biography of the Natural History Museum, celebrating the eccentric personalities who have peopled it and capturing the wonders of scientific endeavour, academic rigour and imagination.

    In Papua New Guinea, a primitive tribe is nearly obliterated by a sickness whose chief symptom is uncontrollable laughter. Across Europe, millions of sheep rub their fleeces raw before collapsing. In England, cows attack their owners in the milking parlors, while in the American West, thousands of deer starve to death in fields full of grass.What these strange conditions–including fatal familial insomnia, kuru, scrapie, and mad cow disease–share is their cause: prions. Prions are ordinary proteins that sometimes go wrong, resulting in neurological illnesses that are always fatal. Even more mysterious and frightening, prions are almost impossible to destroy because they are not alive and have no DNA–and the diseases they bring are now spreading around the world.In The Family That Couldn’t Sleep, essayist and journalist D. T. Max tells the spellbinding story of the prion’s hidden past and deadly future

    Now, Michael Gross gives us the first unauthorized and definitive history of the museum and the juicy details of the lives of the powerful players who made it what it is today. With a colorful cast of characters that includes directors Guy-Philippe Lannes de Montebello, Luigi Palma di Cesnola, and Thomas P. F. Hoving, and a glittering array of supporting players such as John D. Rockefeller, Jr., Annette de la Renta, J. P. Morgan, Brooke Astor, Robert Moses, Diana Vreeland, and Jane Wrightsman, Gross looks at the museum’s rich social history and exposes the secrets behind the upper class’s cultural and philanthropic ambitions. From the trustees to the donors and the curators to the collectors, the startling 138-year tale of the Met and the masterpieces that live inside its walls makes for an astonishing and satisfying read.

    In The Viral Storm, award-winning biologist Nathan Wolfe tells the story of how viruses and human beings have evolved side by side through history; how deadly viruses like HIV, swine flu, and bird flu almost wiped us out in the past; and why modern life has made our species vulnerable to the threat of a global pandemic.Wolfe's research missions to the jungles of Africa and the rain forests of Borneo have earned him the nickname "the Indiana Jones of virus hunters," and here Wolfe takes readers along on his groundbreaking and often dangerous research trips—to reveal the surprising origins of the most deadly diseases and to explain the role that viruses have played in human evolution.In a world where each new outbreak seems worse than the one before, Wolfe points the way forward, as new technologies are brought to bear in the most remote areas of the world to neutralize these viruses and even harness their power for the good of humanity. His provocative vision of the future will change the way we think about viruses, and perhaps remove a potential threat to humanity's survival.

    Now, in The New Science of the Human Past, Reich describes just how the human genome provides not only all the information that a fertilized human egg needs to develop but also contains within it the history of our species. He delineates how the Genomic Revolution and ancient DNA are transforming our understanding of our own lineage as modern humans; how genomics deconstructs the idea that there are no biologically meaningful differences among human populations (though without adherence to pernicious racist hierarchies); and how DNA studies reveal the deep history of human inequality--among different populations, between the sexes, and among individuals within a population.

    She documents her early days in the Democratic Party and the Democratic Alliance, at a time when the party was locked in a no-holds-barred factional conflict. And she chronicles the intense political battles to become mayor of Cape Town, leader of the DA and premier of the Western Cape, in the face of dirty tricks from the ANC and infighting within her own party.This is a story about political intrigue and treachery, floor-crossing and unlikely coalitions, phone tapping and intimidation, false criminal charges and judicial commissions. It documents Zille’s courageous fight against corruption and state capture and her efforts to realign politics and entrench accountability. And it describes a mother’s battle to raise children in the pressured world of South African politics.This book is as frank, honest and unflinching as Helen Zille herself, and will appeal to anyone interested in the story of South African politics over the past fifty years.

    Now he makes the case that living on Mars is not just plausible, but inevitable.It sounds like science fiction, but Stephen Petranek considers it fact: Within twenty years, humans will live on Mars. We'll need to. In this sweeping, provocative book that mixes business, science, and human reporting, Petranek makes the case that living on Mars is an essential back-up plan for humanity and explains in fascinating detail just how it will happen.The race is on. Private companies, driven by iconoclastic entrepreneurs, such as Elon Musk, Jeff Bezos, Paul Allen, and Sir Richard Branson; Dutch reality show and space mission Mars One; NASA; and the Chinese government are among the many groups competing to plant the first stake on Mars and open the door for human habitation. Why go to Mars? Life on Mars has potential life-saving possibilities for everyone on earth. Depleting water supplies, overwhelming climate change, and a host of other disasters — from terrorist attacks to meteor strikes — all loom large. We must become a space-faring species to survive. We have the technology not only to get humans to Mars, but to convert Mars into another habitable planet. It will likely take 300 years to "terraform" Mars, as the jargon goes, but we can turn it into a veritable second Garden of Eden. And we can live there, in specially designed habitations, within the next twenty years.In this exciting chronicle, Petranek introduces the circus of lively characters all engaged in a dramatic effort to be the first to settle the Red Planet. How We'll Live on Mars brings firsthand reporting, interviews with key participants, and extensive research to bear on the question of how we can expect to see life on Mars within the next twenty years.

    

    Kaplan, the bestselling author of Monsoon and Balkan Ghosts, offers a revelatory new prism through which to view global upheavals and to understand what lies ahead for continents and countries around the world.   In The Revenge of Geography, Kaplan builds on the insights, discoveries, and theories of great geographers and geopolitical thinkers of the near and distant past to look back at critical pivots in history and then to look forward at the evolving global scene. Kaplan traces the history of the world’s hot spots by examining their climates, topographies, and proximities to other embattled lands. The Russian steppe’s pitiless climate and limited vegetation bred hard and cruel men bent on destruction, for example, while Nazi geopoliticians distorted geopolitics entirely, calculating that space on the globe used by the British Empire and the Soviet Union could be swallowed by a greater German homeland.   Kaplan then applies the lessons learned to the present crises in Europe, Russia, China, the Indian subcontinent, Turkey, Iran, and the Arab Middle East. The result is a holistic interpretation of the next cycle of conflict throughout Eurasia. Remarkably, the future can be understood in the context of temperature, land allotment, and other physical certainties: China, able to feed only 23 percent of its people from land that is only 7 percent arable, has sought energy, minerals, and metals from such brutal regimes as Burma, Iran, and Zimbabwe, putting it in moral conflict with the United States. Afghanistan’s porous borders will keep it the principal invasion route into India, and a vital rear base for Pakistan, India’s main enemy. Iran will exploit the advantage of being the only country that straddles both energy-producing areas of the Persian Gulf and the Caspian Sea. Finally, Kaplan posits that the United States might rue engaging in far-flung conflicts with Iraq and Afghanistan rather than tending to its direct neighbor Mexico, which is on the verge of becoming a semifailed state due to drug cartel carnage.   A brilliant rebuttal to thinkers who suggest that globalism will trump geography, this indispensable work shows how timeless truths and natural facts can help prevent this century’s looming cataclysms.