The Epigenetics Revolution


Nessa Carey - 2011
    The Human Genome Project finished sequencing human DNA. It seemed it was only a matter of time until we had all the answers to the secrets of life on this planet. The cutting-edge of biology, however, is telling us that we still don't even know all of the questions. How is it that, despite each cell in your body carrying exactly the same DNA, you don't have teeth growing out of your eyeballs or toenails on your liver? How is it that identical twins share exactly the same DNA and yet can exhibit dramatic differences in the way that they live and grow? It turns out that cells read the genetic code in DNA more like a script to be interpreted than a mould that replicates the same result each time. This is epigenetics and it's the fastest-moving field in biology today. The Epigenetics Revolution traces the thrilling path this discipline has taken over the last twenty years. Biologist Nessa Carey deftly explains such diverse phenomena as how queen bees and ants control their colonies, why tortoiseshell cats are always female, why some plants need a period of cold before they can flower, why we age, develop disease and become addicted to drugs, and much more. Most excitingly, Carey reveals the amazing possibilities for humankind that epigenetics offers for us all - and in the surprisingly near future.

Life's Ratchet: How Molecular Machines Extract Order from Chaos


Peter M. Hoffmann - 2012
    But molecules, such as water and sugar, are not alive. So how do our cells--assemblies of otherwise "dead" molecules--come to life, and together constitute a living being? In "Life's Ratchet," physicist Peter M. Hoffmann locates the answer to this age-old question at the nanoscale. The complex molecules of our cells can rightfully be called "molecular machines," or "nanobots"; these machines, unlike any other, work autonomously to create order out of chaos. Tiny electrical motors turn electrical voltage into motion, tiny factories custom-build other molecular machines, and mechanical machines twist, untwist, separate and package strands of DNA. The cell is like a city--an unfathomable, complex collection of molecular worker bees working together to create something greater than themselves. Life, Hoffman argues, emerges from the random motions of atoms filtered through the sophisticated structures of our evolved machinery. We are essentially giant assemblies of interacting nanoscale machines; machines more amazing than can be found in any science fiction novel. Incredibly, the molecular machines in our cells function without a mysterious "life force," nor do they violate any natural laws. Scientists can now prove that life is not supernatural, and that it can be fully understood in the context of science. Part history, part cutting-edge science, part philosophy, "Life's Ratchet" takes us from ancient Greece to the laboratories of modern nanotechnology to tell the story of our quest for the machinery of life.

The ABC of Relativity


Bertrand Russell - 1925
    Ask them the meaning of 'relativity' and few of them will be able to tell you what it is.The basic principles of relativity have not changed since Russell first published his lucid guide for the general reader. The ABC of Relativity is Bertrand Russell's most brilliant work of scientific popularisation. With marvellous lucidity he steers the reader who has no knowledge of maths or physics through the subtleties of Einstein's thinking. In easy, assimilable steps, he explains the theories of special and general relativity and describes their practical application to, amongst much else, discoveries about gravitation and the invention of the hydrogen bomb.

The Beginning of Infinity: Explanations That Transform the World


David Deutsch - 2011
    Taking us on a journey through every fundamental field of science, as well as the history of civilization, art, moral values, and the theory of political institutions, Deutsch tracks how we form new explanations and drop bad ones, explaining the conditions under which progress—which he argues is potentially boundless—can and cannot happen. Hugely ambitious and highly original, The Beginning of Infinity explores and establishes deep connections between the laws of nature, the human condition, knowledge, and the possibility for progress.

Discourse on Method


René Descartes - 1637
    Cress's translation from the French of the Adam and Tannery critical edition is prized for its accuracy, elegance, and economy. The translation featured in the Third Edition has been thoroughly revised from the 1979 First Edition and includes page references to the critical edition for ease of comparison.

Origins: The Scientific Story of Creation


Jim Baggott - 2015
    This book tells the version according to modern science. It is a unique account, starting at the Big Bang and traveling right up to the emergence of humans as conscious intelligent beings, 13.8 billion years later. Chapter by chapter, it sets out the current state of scientific knowledge: the origins of space and time; energy, mass, and light; galaxies, stars, and our sun; the habitable earth, and complex life itself. Drawing together the physical and biological sciences, Baggott recounts what we currently know of our history, highlighting the questions science has yet to answer.

Pensées


Blaise Pascal - 1670
    The Penseés is a collection of philosohical fragments, notes and essays in which Pascal explores the contradictions of human nature in pscyhological, social, metaphysical and - above all - theological terms. Mankind emerges from Pascal's analysis as a wretched and desolate creature within an impersonal universe, but who can be transformed through faith in God's grace.

Genome: the Autobiography of a Species in 23 Chapters


Matt Ridley - 1999
    

A Brief History of Everyone Who Ever Lived: The Stories in Our Genes


Adam Rutherford - 2016
    It is the history of who you are and how you came to be. It is unique to you, as it is to each of the 100 billion modern humans who have ever drawn breath. But it is also our collective story, because in every one of our genomes we each carry the history of our species births, deaths, disease, war, famine, migration, and a lot of sex. Since scientists first read the human genome in 2001, it has been subject to all sorts of claims, counterclaims, and myths. In fact, as Adam Rutherford explains, our genomes should be read not as instruction manuals, but as epic poems. DNA determines far less than we have been led to believe about us as individuals, but vastly more about us as a species. In this captivating journey through the expanding landscape of genetics, Adam Rutherford reveals what our genes now tell us about history, and what history tells us about our genes. From Neanderthals to murder, from redheads to race, dead kings to plague, evolution to epigenetics, this is a demystifying and illuminating new portrait of who we are and how we came to be."

From the Closed World to the Infinite Universe


Alexandre Koyré - 1957
    In the wake of discoveries through the telescope and Copernican theory, the notion of an ordered cosmos of "fixed stars" gave way to that of a universe infinite in both time and space—with significant and far-reaching consequences for human thought. Alexandre Koyré interprets this revolution in terms of the change that occurred in our conception of the universe and our place in it and shows the primacy of this change in the development of the modern world.

Dialogue Concerning the Two Chief World Systems


Galileo Galilei - 1632
    Using the dialogue form, a genre common in classical philosophical works, Galileo masterfully demonstrates the truth of the Copernican system over the Ptolemaic one, proving, for the first time, that the earth revolves around the sun. Its influence is incalculable. The Dialogue is not only one of the most important scientific treatises ever written, but a work of supreme clarity and accessibility, remaining as readable now as when it was first published. This edition uses the definitive text established by the University of California Press, in Stillman Drake’s translation, and includes a Foreword by Albert Einstein and a new Introduction by J. L. Heilbron.

The Myth of Sisyphus


Albert Camus - 1942
    They have transformed the way we see ourselves—and each other. They have inspired debate, dissent, war and revolution. They have enlightened, outraged, provoked and comforted. They have enriched lives—and destroyed them. Now Penguin brings you the works of the great thinkers, pioneers, radicals and visionaries whose ideas shook civilization and helped make us who we are. Inspired by the myth of a man condemned to ceaselessly push a rock up a mountain and watch it roll back to the valley below, The Myth of Sisyphus transformed twentieth-century philosophy with its impassioned argument for the value of life in a world without religious meaning.

Big Bang: The Origin of the Universe


Simon Singh - 2004
    In this amazingly comprehensible history of the universe, Simon Singh decodes the mystery behind the Big Bang theory, lading us through the development of one of the most extraordinary, important, and awe-inspiring theories in science.

Why Is Sex Fun? The Evolution of Human Sexuality (Science Masters)


Jared Diamond - 1997
    Here is a delightfully entertaining and enlightening look at the unique sex lives of humans.

The Structure of Scientific Revolutions


Thomas S. Kuhn - 1962
    The Structure of Scientific Revolutions is that kind of book. When it was first published in 1962, it was a landmark event in the history and philosophy of science. Fifty years later, it still has many lessons to teach. With The Structure of Scientific Revolutions, Kuhn challenged long-standing linear notions of scientific progress, arguing that transformative ideas don’t arise from the day-to-day, gradual process of experimentation and data accumulation but that the revolutions in science, those breakthrough moments that disrupt accepted thinking and offer unanticipated ideas, occur outside of “normal science,” as he called it. Though Kuhn was writing when physics ruled the sciences, his ideas on how scientific revolutions bring order to the anomalies that amass over time in research experiments are still instructive in our biotech age. This new edition of Kuhn’s essential work in the history of science includes an insightful introduction by Ian Hacking, which clarifies terms popularized by Kuhn, including paradigm and incommensurability, and applies Kuhn’s ideas to the science of today. Usefully keyed to the separate sections of the book, Hacking’s introduction provides important background information as well as a contemporary context.  Newly designed, with an expanded index, this edition will be eagerly welcomed by the next generation of readers seeking to understand the history of our perspectives on science.