The most fatal virus known to science, rabies — a disease that spreads avidly from animals to humans — kills nearly one hundred percent of its victims once the infection takes root in the brain. In this critically acclaimed exploration, journalist Bill Wasik and veterinarian Monica Murphy chart four thousand years of the history, science, and cultural mythology of rabies. From Greek myths to zombie flicks, from the laboratory heroics of Louis Pasteur to the contemporary search for a lifesaving treatment, Rabid is a fresh and often wildly entertaining look at one of humankind’s oldest and most fearsome foes.

    From distressed small communities in Central Appalachia to wealthy suburbs; from disparate cities to once-idyllic farm towns; it's a heartbreaking trajectory that illustrates how this national crisis has persisted for so long and become so firmly entrenched. Beginning with a single dealer who lands in a small Virginia town and sets about turning high school football stars into heroin overdose statistics, Macy endeavors to answer a grieving mother's question-why her only son died-and comes away with a harrowing story of greed and need. From the introduction of OxyContin in 1996, Macy parses how America embraced a medical culture where overtreatment with painkillers became the norm. In some of the same distressed communities featured in her bestselling book Factory Man, the unemployed use painkillers both to numb the pain of joblessness and pay their bills, while privileged teens trade pills in cul-de-sacs, and even high school standouts fall prey to prostitution, jail, and death.Through unsparing, yet deeply human portraits of the families and first responders struggling to ameliorate this epidemic, each facet of the crisis comes into focus. In these politically fragmented times, Beth Macy shows, astonishingly, that the only thing that unites Americans across geographic and class lines is opioid drug abuse. But in a country unable to provide basic healthcare for all, Macy still finds reason to hope-and signs of the spirit and tenacity necessary in those facing addiction to build a better future for themselves and their families.

    His long-awaited Inside the Middle East challenges widely-accepted perceptions and provides a gripping and uniquely enlightening guide to make sense of the events unfolding in the region—to answer how the Arab world got to this point, what is currently happening, what the ramifications will be, how they will affect Israel, and what actions must immediately be undertaken, including how Western leaders need to respond.Melamed considers all the major power players in the Middle East, explains the underlying issues, and creates a three-dimensional picture, an illustration that connects the dots and provides a fascinating roadmap. He elucidates developments such as the Arab Spring, the downfall of the Muslim Brotherhood, the rise of ISIS, the epic Sunni-Shiite animosity, the essence of the war in Syria, the role of the Caliphate and Jihad, and the looming nuclear arms race. He also provides a rare opportunity to journey into the psyche of Arab society. Look through the lens of its leaders and its most ruthless terrorists. See what makes them tick and what they want. Discover how they can be overtaken.This unparalleled volume is a milestone in our understanding of the Middle East. It is the untold story of the struggles that will shape the region, and the world, for decades to come, and a groundbreaking guide that will shake you to the core, force you to reevalute your outlook, and give you tips to navigate the future.From author Avi Melamed:The conflicts in the Middle East grow more confusing and dangerous every day.In my encounters with thousands of people from across the world - from global leaders to high school students - I know there is deep and intense thirst for knowledge because today understanding the Middle East is not optional – it’s mandatory.My new book, Inside the Middle East: Making Sense of the Most Dangerous and Complicated Region on Earth is based on my decades of advisory, counterterrorism, education, and intelligence – positions - as well as my intimate connections throughout the Arab world.The book also provides the building blocks and database to understand the contemporary Middle East, offers a unique insight into the Arab world, and is “a GPS to help you navigate the dramatically changing Middle East.”In the book, I also offer an out of the box idea that could lead to a positive breakthrough in the Israeli- Palestinian conflict.

    Twenty-four true, wide-ranging tales of crime, history, human behavior, illness, and ethics, told from the personal perspective of the author, an eminent physician-lawyer who uses the stories to illustrate the principles of human genetics and to discuss the broader issues.

    The Structure of Scientific Revolutions is that kind of book. When it was first published in 1962, it was a landmark event in the history and philosophy of science. Fifty years later, it still has many lessons to teach. With The Structure of Scientific Revolutions, Kuhn challenged long-standing linear notions of scientific progress, arguing that transformative ideas don’t arise from the day-to-day, gradual process of experimentation and data accumulation but that the revolutions in science, those breakthrough moments that disrupt accepted thinking and offer unanticipated ideas, occur outside of “normal science,” as he called it. Though Kuhn was writing when physics ruled the sciences, his ideas on how scientific revolutions bring order to the anomalies that amass over time in research experiments are still instructive in our biotech age. This new edition of Kuhn’s essential work in the history of science includes an insightful introduction by Ian Hacking, which clarifies terms popularized by Kuhn, including paradigm and incommensurability, and applies Kuhn’s ideas to the science of today. Usefully keyed to the separate sections of the book, Hacking’s introduction provides important background information as well as a contemporary context.  Newly designed, with an expanded index, this edition will be eagerly welcomed by the next generation of readers seeking to understand the history of our perspectives on science.

    A group of young scientists, under the guidance of Dr. George Church, the most brilliant geneticist of our time, works to make fantasy reality by sequencing the DNA of a frozen woolly mammoth harvested from above the Arctic circle, and splicing elements of that sequence into the DNA of a modern elephant. Will they be able to turn the hybrid cells into a functional embryo and bring the extinct creatures to life in our modern world?Along with Church and his team of Harvard scientists, a world-famous conservationist and a genius Russian scientist plan to turn a tract of the Siberian tundra into Pleistocene Park, populating the permafrost with ancient herbivores as a hedge against an environmental ticking time bomb.

    Two days later, she got her first glimpse of the famous, terrifying jaws up close and she was instantly hooked; her fascination soon yielded to obsession-and an invitation to return for a full season. But as Casey readied herself for the eight-week stint, she had no way of preparing for what she would find among the dangerous, forgotten islands that have banished every campaign for civilization in the past two hundred years.

    America faced a troubling question: What happened? How was this epidemic allowed to spread so far before it was taken seriously? In answering these questions, Shilts weaves the disparate threads into a coherent story, pinning down every evasion and contradiction at the highest levels of the medical, political, and media establishments. Shilts shows that the epidemic spread wildly because the federal government put budget ahead of the nation's welfare; health authorities placed political expediency before the public health; and scientists were often more concerned with international prestige than saving lives. Against this backdrop, Shilts tells the heroic stories of individuals in science and politics, public health and the gay community, who struggled to alert the nation to the enormity of the danger it faced. And the Band Played On is both a tribute to these heroic people and a stinging indictment of the institutions that failed the nation so badly.

    Now Sobel brings her full talents to bear on what is perhaps her most ambitious topic to date-the planets of our solar system. Sobel explores the origins and oddities of the planets through the lens of popular culture, from astrology, mythology, and science fiction to art, music, poetry, biography, and history. Written in her characteristically graceful prose, The Planets is a stunningly original celebration of our solar system and offers a distinctive view of our place in the universe. * A New York Times extended bestseller * A Featured Alternate of the Book-of-the-Month Club, History Book Club, Scientific American Book Club, and Natural Science Book Club * Includes 11 full-color illustrations by artist Lynette R. Cook BACKCOVER: "[The Planets] lets us fall in love with the heavens all over again." -The New York Times Book Review "Playful . . . lyrical . . . a guided tour so imaginative that we forget we're being educated as we're being entertained." -Newsweek " [Sobel] has outdone her extraordinary talent for keeping readers enthralled. . . . Longitude and Galileo's Daughter were exciting enough, but The Planets has a charm of its own . . . . A splendid and enticing book." -San Francisco Chronicle "A sublime journey. [Sobel's] writing . . . is as bright as the sun and its thinking as star-studded as the cosmos." -The Atlanta Journal-Constitution "An incantatory serenade to the Solar System. Grade A-" -Entertainment Weekly "Like Sobel's [Longitude and Galileo's Daughter] . . . [The Planets] combines masterful storytelling with clear, engaging explanations of the essential scientific facts." -Physics World

    Identified in the paper as "Yeoman," to protect his identity, the writer roamed eleven states and six thousand miles, jolting the nation with his dispatches about slavery and the extremism of its defenders.This extraordinary journey would also re-shape the nation's landscape, driving "Yeoman"--real name Frederick Law Olmsted--to embark on his career as America's first and foremost architect of urban parks and other public spaces.Over a century and half later, there are echoes of the pre-Civil War in the angry ferment and fracturing of our own time. Is America still one country? Tony Horwitz, like Olmsted a Yankee and roving scribe, sets forth to find out by retracing Yeoman's journey through the South. Following his route and whenever possible his mode of transport--rail, riverboats, in the saddle--Horwitz travels Appalachia, down the Ohio and Mississippi, through Kentucky, Tennessee, Louisiana, and across Texas to the Rio Grande. Venturing, as Olmsted did, far off the beaten paths, Horwitz discovers colorful traces of an old weird America, shocking vestiges of the Cotton Kingdom, and strange new mutations that have sprung from its roots.The result is a masterpiece in the tradition of Great Plains, Bad Land, and the author's own classic, Confederates in the Attic. Spying on the South is an intrepid, wise, and frequently hilarious expedition through an outsized landscape and its equally outsized state of mind. It is also a probing and poignant study of the young Olmsted, whose own life, and thinking about landscape and society, would be forever altered by his Southern odyssey.

    Now, in What the Dog Saw, he brings together, for the first time, the best of his writing from The New Yorker over the same period. Here you'll find the bittersweet tale of the inventor of the birth control pill, and the dazzling creations of pasta sauce pioneer Howard Moscowitz. Gladwell sits with Ron Popeil, the king of the American kitchen, as he sells rotisserie ovens, and divines the secrets of Cesar Millan, the "dog whisperer" who can calm savage animals with the touch of his hand. He explores intelligence tests and ethnic profiling and why it was that employers in Silicon Valley once tripped over themselves to hire the same college graduate.

    The meme is also one of the most important--and controversial--concepts to emerge since 'The Origin of the Species' appeared nearly 150 years ago.In 'The Meme Machine' Susan Blackmore boldly asserts: "Just as the design of our bodies can be understood only in terms of natural selection, so the design of our minds can be understood only in terms of memetic selection." Indeed, Blackmore shows that once our distant ancestors acquired the crucial ability to imitate, a second kind of natural selection began, a survival of the fittest amongst competing ideas and behaviors. Ideas and behaviors that proved most adaptive - making tools, for example, or using language--survived and flourished, replicating themselves in as many minds as possible. These memes then passed themselves on from generation to generation by helping to ensure that the genes of those who acquired them also survived and reproduced. Applying this theory to many aspects of human life, Blackmore offers brilliant explanations for why we live in cities, why we talk so much, why we can't stop thinking, why we behave altruistically, how we choose our mates, and much more.With controversial implications for our religious beliefs, our free will, our very sense of "self," 'The Meme Machine' offers a provocative theory everyone will soon be talking about.

    They were hunter-gatherers, consummate foraging experts, but taking the world as they found it. Then a revolution occurred – our ancestors’ interaction with other species changed. They began to tame them. The human population boomed; civilization began.In her new book, Tamed, Alice Roberts uncovers the amazing deep history of ten familiar species with incredible wild pasts: dogs, apples and wheat; cattle; potatoes and chickens; rice, maize, and horses – and, finally, humans. Alice Roberts not only reveals how becoming part of our world changed these animals and plants, but shows how they became our allies, essential to the survival and success of our own species – and to our future.Enlightening, wide-ranging and endlessly fascinating, Tamed is an epic story, encompassing hundreds of thousands of years of history and archaeology alongside cutting-edge genetics and anthropology. Yet it is also a deeply personal journey that will change how we see ourselves and the species on which we have left our mark.

    He provides information on how cannabis works with the body's own system, how best to prepare and administer it, and how to modify and control dosage. This newly revised edition is now completely up-to-date with the latest information on the body's encannabinoid system, which is now understood to control emotion, appetite, and memory, delivery and dosing of cannabis, including e-cigarette designs, additional varietals, and a new system for classification, as well as 21 additional ailments and conditions that can be treated with medical marijuana. There are currently more than 4.2 million medical cannabis patients in the United States, and there are 29 states plus the District of Columbia where medical cannabis is legal.

    Yet in the low center of the state is a near wilderness, larger than most national parks, which has been known since the seventeenth century as the Pine Barrens.The term refers to the predominant trees in the vast forests that cover the area and to the quality of the soils below, which are too sandy and acid to be good for farming. On all sides, however, developments of one kind or another have gradually moved in, so that now the central and integral forest is reduced to about a thousand square miles. Although New Jersey has the heaviest population density of any state, huge segments of the Pine Barrens remain uninhabited. The few people who dwell in the region, the "Pineys," are little known and often misunderstood. Here McPhee uses his uncanny skills as a journalist to explore the history of the region and describe the people "and their distinctive folklore" who call it home.