Lisa Sanders, author of the monthly New York Times Magazine column "Diagnosis," the inspiration for the hit Fox TV series House, M.D.The experience of being ill can be like waking up in a foreign country. Life, as you formerly knew it, is on hold while you travel through this other world as unknown as it is unexpected. When I see patients in the hospital or in my office who are suddenly, surprisingly ill, what they really want to know is, ‘What is wrong with me?’ They want a road map that will help them manage their new surroundings. The ability to give this unnerving and unfamiliar place a name, to know it–on some level–restores a measure of control, independent of whether or not that diagnosis comes attached to a cure. Because, even today, a diagnosis is frequently all a good doctor has to offer.A healthy young man suddenly loses his memory–making him unable to remember the events of each passing hour. Two patients diagnosed with Lyme disease improve after antibiotic treatment–only to have their symptoms mysteriously return. A young woman lies dying in the ICU–bleeding, jaundiced, incoherent–and none of her doctors know what is killing her. In Every Patient Tells a Story, Dr. Lisa Sanders takes us bedside to witness the process of solving these and other diagnostic dilemmas, providing a firsthand account of the expertise and intuition that lead a doctor to make the right diagnosis.Never in human history have doctors had the knowledge, the tools, and the skills that they have today to diagnose illness and disease. And yet mistakes are made, diagnoses missed, symptoms or tests misunderstood. In this high-tech world of modern medicine, Sanders shows us that knowledge, while essential, is not sufficient to unravel the complexities of illness. She presents an unflinching look inside the detective story that marks nearly every illness–the diagnosis–revealing the combination of uncertainty and intrigue that doctors face when confronting patients who are sick or dying. Through dramatic stories of patients with baffling symptoms, Sanders portrays the absolute necessity and surprising difficulties of getting the patient’s story, the challenges of the physical exam, the pitfalls of doctor-to-doctor communication, the vagaries of tests, and the near calamity of diagnostic errors. In Every Patient Tells a Story, Dr. Sanders chronicles the real-life drama of doctors solving these difficult medical mysteries that not only illustrate the art and science of diagnosis, but often save the patients’ lives.

    Helens in southwestern Washington State. Still, no one was prepared when a cataclysmic eruption blew the top off of the mountain, laying waste to hundreds of square miles of land and killing fifty-seven people. Steve Olson interweaves vivid personal stories with the history, science, and economic forces that influenced the fates and futures of those around the volcano. Eruption delivers a spellbinding narrative of an event that changed the course of volcanic science, and an epic tale of our fraught relationship with the natural world.

    A sensational disappearance that made headlines around the world. A quest for truth that leads to death, madness or disappearance for those who seek to solve it. The Lost City of Z is a blockbuster adventure narrative about what lies beneath the impenetrable jungle canopy of the Amazon.After stumbling upon a hidden trove of diaries, New Yorker writer David Grann set out to solve "the greatest exploration mystery of the 20th century": What happened to the British explorer Percy Fawcett & his quest for the Lost City of Z?In 1925, Fawcett ventured into the Amazon to find an ancient civilization, hoping to make one of the most important discoveries in history. For centuries Europeans believed the world's largest jungle concealed the glittering kingdom of El Dorado. Thousands had died looking for it, leaving many scientists convinced that the Amazon was truly inimical to humans. But Fawcett, whose daring expeditions inspired Conan Doyle's The Lost World, had spent years building his scientific case. Captivating the imagination of millions round the globe, Fawcett embarked with his 21-year-old son, determined to prove that this ancient civilisation--which he dubbed Z--existed. Then his expedition vanished. Fawcett's fate, & the tantalizing clues he left behind about Z, became an obsession for hundreds who followed him into the uncharted wilderness. For decades scientists & adventurers have searched for evidence of Fawcett's party & the lost City of Z. Countless have perished, been captured by tribes or gone mad. As Grann delved ever deeper into the mystery surrounding Fawcett's quest, & the greater mystery of what lies within the Amazon, he found himself, like the generations who preceded him, being irresistibly drawn into the jungle's green hell. His quest for the truth & discoveries about Fawcett's fate & Z form the heart of this complexly enthralling narrative.

    Gleick's story begins at the turn of the twentieth century with the young H. G. Wells writing and rewriting the fantastic tale that became his first book, an international sensation, The Time Machine. A host of forces were converging to transmute the human understanding of time, some philosophical and some technological the electric telegraph, the steam railroad, the discovery of buried civilizations, and the perfection of clocks. Gleick tracks the evolution of time travel as an idea in the culture from Marcel Proust to Doctor Who, from Woody Allen to Jorge Luis Borges. He explores the inevitable looping paradoxes and examines the porous boundary between pulp fiction and modern physics. Finally, he delves into a temporal shift that is unsettling our own moment: the instantaneous wired world, with its all-consuming present and vanishing future.

    Randall never gave sleep much thought. That is, until he began sleepwalking. One midnight crash into a hallway wall sent him on an investigation into the strange science of sleep.In Dreamland, Randall explores the research that is investigating those dark hours that make up nearly a third of our lives. Taking readers from military battlefields to children’s bedrooms, Dreamland shows that sleep isn't as simple as it seems. Why did the results of one sleep study change the bookmakers’ odds for certain Monday Night Football games? Do women sleep differently than men? And if you happen to kill someone while you are sleepwalking, does that count as murder?This book is a tour of the often odd, sometimes disturbing, and always fascinating things that go on in the peculiar world of sleep. You’ll never look at your pillow the same way again.

    When temperatures drop below 56°F, tin crumbles into powder. Were the soldiers of the Grande Armée acutee fatally weakened by cold because the buttons of their uniforms fell apart? How different our world might be if tin did not disintegrate at low temperatures and the French had continued their eastward expansion! This fascinating book tells the stories of seventeen molecules that, like the tin of those buttons, greatly influenced the course of history. These molecules provided the impetus for early exploration and made possible the ensuing voyages of discovery. They resulted in grand feats of engineering and spurred advances in medicine; lie behind changes in gender roles, in law, and in the environment; and have determined what we today eat, drink, and wear. Showing how a change as small as the position of an atom can lead to enormous differences in the properties of a substance, the authors reveal the astonishing chemical connections among seemingly unrelated events. Napoleon's Buttons offers a novel way to understand how our contemporary world works and how our civilization has been shaped over time.

    But in recent decades, these claims have eroded, or even been disproven outright, by a revolution in the study of animal cognition. Take the way octopuses use coconut shells as tools; elephants that classify humans by age, gender, and language; or Ayumu, the young male chimpanzee at Kyoto University whose flash memory puts that of humans to shame. Based on research involving crows, dolphins, parrots, sheep, wasps, bats, whales, and of course chimpanzees and bonobos, Frans de Waal explores both the scope and the depth of animal intelligence. He offers a firsthand account of how science has stood traditional behaviorism on its head by revealing how smart animals really are, and how we’ve underestimated their abilities for too long.People often assume a cognitive ladder, from lower to higher forms, with our own intelligence at the top. But what if it is more like a bush, with cognition taking different forms that are often incomparable to ours? Would you presume yourself dumber than a squirrel because you’re less adept at recalling the locations of hundreds of buried acorns? Or would you judge your perception of your surroundings as more sophisticated than that of a echolocating bat? De Waal reviews the rise and fall of the mechanistic view of animals and opens our minds to the idea that animal minds are far more intricate and complex than we have assumed. De Waal’s landmark work will convince you to rethink everything you thought you knew about animal—and human—intelligence.

    Known for her hilariously acerbic observations on her blog, People I Want to Punch in the Throat, Mann now brings her sharp wit to bear on suburban life, marriage, and motherhood in this laugh-out-loud collection of essays. From the politics of joining a play group, to the thrill of mothers’ night out at the gun range, to the rewards of your most meaningful relationship (the one you have with your cleaning lady), nothing is sacred or off-limits. So the next time you find yourself wearing fuzzy bunny pajamas in the school carpool line or accidentally stuck at a co-worker’s swingers party, just think, What would Jen Mann do? Or better yet, buy her book.

    In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    Syed has maintained his innocence, and Rabia Chaudry, a family friend, has always believed him. By 2013, after almost all appeals had been exhausted, Rabia contacted Sarah Koenig, a producer at This American Life, in hopes of finding a journalist who could shed light on Adnan’s story. In 2014, Koenig's investigation turned into Serial, a Peabody Award-winning podcast with more than 500 million international listenersBut Serial did not tell the whole story. In this compelling narrative, Rabia Chaudry presents new key evidence that she maintains dismantles the State's case: a potential new suspect, forensics indicating Hae was killed and kept somewhere for almost half a day, and documentation withheld by the State that destroys the cell phone evidence -- among many other points -- and she shows how fans of Serial joined a crowd-sourced investigation into a case riddled with errors and strange twists. Adnan's Story also shares Adnan’s life in prison, and weaves in his personal reflections, including never-before-seen letters. Chaudry, who is committed to exonerating Adnan, makes it clear that justice is yet to be achieved in this much examined case.

    Both Nick and his character, Ron Swanson, are known for their humor and patriotism in equal measure.After the great success of his autobiography, Paddle Your Own Canoe, Offerman now focuses on the lives of those who inspired him. From George Washington to Willie Nelson, he describes twenty-one heroic figures and why they inspire in him such great meaning. He combines both serious history with light-hearted humor—comparing, say, Benjamin Franklin’s abstinence from daytime drinking to his own sage refusal to join his construction crew in getting plastered on the way to work. The subject matter also allows Offerman to expound upon his favorite topics, which readers love to hear—areas such as religion, politics, woodworking and handcrafting, agriculture, creativity, philosophy, fashion, and, of course, meat.

    In The Botany of Desire, Michael Pollan ingeniously demonstrates how people and domesticated plants have formed a similarly reciprocal relationship. He masterfully links four fundamental human desires—sweetness, beauty, intoxication, and control—with the plants that satisfy them: the apple, the tulip, marijuana, and the potato. In telling the stories of four familiar species, Pollan illustrates how the plants have evolved to satisfy humankind’s most basic yearnings. And just as we’ve benefited from these plants, we have also done well by them. So who is really domesticating whom?

    Growing up in a working-class Long Island family, Massimino catapulted himself to Columbia and then MIT, only to flunk his qualifying exams and be rejected twice by NASA before making it to the final round of astronaut selection—where he was told his poor eyesight meant he’d never make the cut. But even that couldn’t stop him from finally earning his wings, making the jump to training in T-38 Air Force jets and preparing his body—and soul—for the journey to the cosmos.Taking us through the surreal wonder and beauty of his first spacewalk, the tragedy of losing friends in the Columbia shuttle accident, and the development of his enduring love for the Hubble telescope—which he’d be tasked with saving on his final mission— Massimino has written an ode to never giving up and the power of teamwork to make anything possible. Spaceman invites us into a rare, wonderful world where the nerdiest science meets the most thrilling adventure, and pulls back a curtain on just what having “the right stuff” really means.

    But Charlie wasn't lighting fires alone: he had an accomplice, his girlfriend Tonya Bundick. Through her depiction of the dangerous shift that happened in their passionate relationship, Hesse brilliantly brings to life the once-thriving coastal community and its distressed inhabitants, who had already been decimated by a punishing economy before they were terrified by a string of fires they could not explain. Incorporating this drama into the long-overlooked history of arson in the United States, American Fire re-creates the anguished nights that this quiet county spent lit up in flames, mesmerizingly evoking a microcosm of rural America - a land half gutted before the fires even began.

    The epidemics of obesity, heart disease, and diabetes are not tied to the overabundance of fat or carbs or any other specific nutrient. Instead, we have been led astray by the growing divide between flavor - the tastes we crave - and the underlying nutrition. Since the late 1940s, we have been slowly leeching flavor out of the food we grow. Those perfectly round, red tomatoes that grace our supermarket aisles today are mostly water, and the big breasted chickens on our dinner plates grow three times faster than they used to, leaving them dry and tasteless. Simultaneously, we have taken great leaps forward in technology, allowing us to produce in the lab the very flavors that are being lost on the farm. Thanks to this largely invisible epidemic, seemingly healthy food is becoming more like junk food: highly craveable but nutritionally empty. We have unknowingly interfered with an ancient chemical language - flavor - that evolved to guide our nutrition, not destroy it.With in-depth historical and scientific research, The Dorito Effect casts the food crisis in a fascinating new light, weaving an enthralling tale of how we got to this point and where we are headed. We've been telling ourselves that our addiction to flavor is the problem, but it is actually the solution. We are on the cusp of a new revolution in agriculture that will allow us to eat healthier and live longer by enjoying flavor the way nature intended.