Book picks similar to
The Great American Drug Deal: A New Prescription for Innovative and Affordable Medicines by Peter Kolchinsky
biotech
non-fiction
healthcare
business
The Science of Fear: Why We Fear the Things We Shouldn't--and Put Ourselves in Greater Danger
Daniel Gardner - 2008
And yet, we are the safest and healthiest humans in history. Irrational fear seems to be taking over, often with tragic results. For example, in the months after 9/11, when people decided to drive instead of fly—believing they were avoiding risk—road deaths rose by more than 1,500. In this fascinating, lucid, and thoroughly entertaining examination of how humans process risk, journalist Dan Gardner had the exclusive cooperation of Paul Slovic, the world renowned risk-science pioneer, as he reveals how our hunter gatherer brains struggle to make sense of a world utterly unlike the one that made them. Filled with illuminating real world examples, interviews with experts, and fast-paced, lean storytelling, The Science of Fear shows why it is truer than ever that the worst thing we have to fear is fear itself.
Enlightenment Now: The Case for Reason, Science, Humanism, and Progress
Steven Pinker - 2018
Instead, follow the data: In seventy-five jaw-dropping graphs, Pinker shows that life, health, prosperity, safety, peace, knowledge, and happiness are on the rise, not just in the West, but worldwide. This progress is not the result of some cosmic force. It is a gift of the Enlightenment: the conviction that reason and science can enhance human flourishing.Far from being a naïve hope, the Enlightenment, we now know, has worked. But more than ever, it needs a vigorous defense. The Enlightenment project swims against currents of human nature–tribalism, authoritarianism, demonization, magical thinking–which demagogues are all too willing to exploit. Many commentators, committed to political, religious, or romantic ideologies, fight a rearguard action against it. The result is a corrosive fatalism and a willingness to wreck the precious institutions of liberal democracy and global cooperation.With intellectual depth and literary flair, Enlightenment Now makes the case for reason, science, and humanism: the ideals we need to confront our problems and continue our progress.
Junkyard Planet: Travels in the Billion-Dollar Trash Trade
Adam Minter - 2013
In Junkyard Planet, Adam Minter—veteran journalist and son of an American junkyard owner—travels deeply into a vast, often hidden, multibillion-dollar industry that’s transforming our economy and environment.Minter takes us from back-alley Chinese computer recycling operations to high-tech facilities capable of processing a jumbo jet’s worth of recyclable trash every day. Along the way, we meet an unforgettable cast of characters who've figured out how to build fortunes from what we throw away: Leonard Fritz, a young boy "grubbing" in Detroit's city dumps in the 1930s; Johnson Zeng, a former plastics engineer roaming America in search of scrap; and Homer Lai, an unassuming barber turned scrap titan in Qingyuan, China. Junkyard Planet reveals how “going green” usually means making money—and why that’s often the most sustainable choice, even when the recycling methods aren’t pretty.With unmatched access to and insight on the junk trade, and the explanatory gifts and an eye for detail worthy of a John McPhee or William Langewiesche, Minter traces the export of America’s recyclables and the massive profits that China and other rising nations earn from it. What emerges is an engaging, colorful, and sometimes troubling tale of consumption, innovation, and the ascent of a developing world that recognizes value where Americans don’t. Junkyard Planet reveals that we might need to learn a smarter way to take out the trash.
The Vaccine Race: Science, Politics, and the Human Costs of Defeating Disease
Meredith Wadman - 2017
In June 1962, a young biologist in Philadelphia, using tissue extracted from an aborted fetus from Sweden, produced safe, clean cells that allowed the creation of vaccines against rubella and other common childhood diseases. Two years later, in the midst of a devastating German measles epidemic, his colleague developed the vaccine that would one day wipe out homegrown rubella. The rubella vaccine and others made with those fetal cells have protected more than 150 million people in the United States, the vast majority of them preschoolers. The new cells and the method of making them also led to vaccines that have protected billions of people around the world from polio, rabies, chicken pox, measles, hepatitis A, shingles and adenovirus. Meredith Wadman’s masterful account recovers not only the science of this urgent race, but also the political roadblocks that nearly stopped the scientists. She describes the terrible dilemmas of pregnant women exposed to German measles and recounts testing on infants, prisoners, orphans, and the intellectually disabled, which was common in the era. These events take place at the dawn of the battle over using human fetal tissue in research, during the arrival of big commerce in campus labs, and as huge changes take place in the laws and practices governing who “owns” research cells and the profits made from biological inventions. It is also the story of yet one more unrecognized woman whose cells have been used to save countless lives. With another frightening virus imperiling pregnant women on the rise today, no medical story could have more human drama, impact, or urgency today than The Vaccine Race.
First Principles: What America's Founders Learned from the Greeks and Romans and How That Shaped Our Country
Thomas E. Ricks - 2020
On every page I learned something new. Read it every night if you want to restore your faith in our country." —James Mattis, General, U.S. Marines (ret.) & 26th Secretary of Defense The Pulitzer Prize-winning journalist and #1 New York Times bestselling author offers a revelatory new book about the founding fathers, examining their educations and, in particular, their devotion to the ancient Greek and Roman classics—and how that influence would shape their ideals and the new American nation.On the morning after the 2016 presidential election, Thomas Ricks awoke with a few questions on his mind: What kind of nation did we now have? Is it what was designed or intended by the nation’s founders? Trying to get as close to the source as he could, Ricks decided to go back and read the philosophy and literature that shaped the founders’ thinking, and the letters they wrote to each other debating these crucial works—among them the Iliad, Plutarch’s Lives, and the works of Xenophon, Epicurus, Aristotle, Cato, and Cicero. For though much attention has been paid the influence of English political philosophers, like John Locke, closer to their own era, the founders were far more immersed in the literature of the ancient world.The first four American presidents came to their classical knowledge differently. Washington absorbed it mainly from the elite culture of his day; Adams from the laws and rhetoric of Rome; Jefferson immersed himself in classical philosophy, especially Epicureanism; and Madison, both a groundbreaking researcher and a deft politician, spent years studying the ancient world like a political scientist. Each of their experiences, and distinctive learning, played an essential role in the formation of the United States. In examining how and what they studied, looking at them in the unusual light of the classical world, Ricks is able to draw arresting and fresh portraits of men we thought we knew.First Principles follows these four members of the Revolutionary generation from their youths to their adult lives, as they grappled with questions of independence, and forming and keeping a new nation. In doing so, Ricks interprets not only the effect of the ancient world on each man, and how that shaped our constitution and government, but offers startling new insights into these legendary leaders.
iGen: Why Today’s Super-Connected Kids Are Growing Up Less Rebellious, More Tolerant, Less Happy--and Completely Unprepared for Adulthood--and What That Means for the Rest of Us
Jean M. Twenge - 2017
Born in the mid-1990s to the mid-2000s and later, iGen is the first generation to spend their entire adolescence in the age of the smartphone. With social media and texting replacing other activities, iGen spends less time with their friends in person—perhaps why they are experiencing unprecedented levels of anxiety, depression, and loneliness. But technology is not the only thing that makes iGen distinct from every generation before them; they are also different in how they spend their time, how they behave, and in their attitudes toward religion, sexuality, and politics. They socialize in completely new ways, reject once sacred social taboos, and want different things from their lives and careers. More than previous generations, they are obsessed with safety, focused on tolerance, and have no patience for inequality. iGen is also growing up more slowly than previous generations: eighteen-year-olds look and act like fifteen-year-olds used to. As this new group of young people grows into adulthood, we all need to understand them: Friends and family need to look out for them; businesses must figure out how to recruit them and sell to them; colleges and universities must know how to educate and guide them. And members of iGen also need to understand themselves as they communicate with their elders and explain their views to their older peers. Because where iGen goes, so goes our nation—and the world.
Pain Killer: A "Wonder" Drug's Trail of Addiction and Death
Barry Meier - 2003
From the start, the drug's manufacturer aggressively marketed its patented time-release formula as a breakthrough in the effort to reduce prescription drug abuse. It wasn't long, however, before thrill-seeking teenagers shattered that illusion of safety; by simply crushing an "Oxy," they were able to tap into a high so seductive it would come to dominate their lives. Some patients, seeking relief from pain, also found themselves drawn to the drug's dark side. Pain Killer takes readers on a journey of discovery that begins with the true story of Lindsay, a high-school cheerleader in Virginia who gets hooked on Oxys, and expands outward to explore the critical issues of legitimate pain management, prescription drug abuse, and how the misuse of science by the drug industry threatens the public good. With the fast-rising abuse of prescription drugs by young people ringing alarm bells within government, the how and why behind the OxyContin disaster is a gripping read not only for parents, but also for medical professionals, community leaders, business executives, and all those concerned with this crisis. The dangers described in Pain Killer also reverberate far beyond the threat from a single drug at a particular moment in time. The focus of our government's war on drugs has clearly misled many of us into thinking that only illegal drugs smuggled from beyond our borders can be abused. As Meier tells the dramatic story, some of the most deadly substances are produced and sold legally right here at home.THE EXTRAORDINARY AND TRUE STORY OF OXYCONTIN EQUAL PARTS crime thriller, medical detective story, and business exposé, Pain Killer takes a hard-hitting look at how a powerful drug touted as the salvation for millions triggered a national tragedy. At its inception, the legal narcotic OxyContin was seen as a pharmaceutical dream, a "wonder" drug that would herald a sea change in medical care while reaping vast profits for its maker. It did do that; but it also unleashed a public health crisis that cut a swath of despair and crime through unsuspecting small towns, suburbs, and cities across the country. As reports of OxyContin overdoses made front-page and network news, doctors, narcotics agents, regulators, industry executives, and lawmakers raced in, scrambling to slow the damage. Behind it all stood one of America's wealthiest families, and a drug company whose relentless promotion helped fuel the problem Written by award-winning journalist Barry Meier, whose special report in the New York Times triggered national interest in OxyContin, Pain Killer chronicles the rise of the multibillion dollar pain management industry and lays bare its excesses and abuses.
Weapons of Math Destruction: How Big Data Increases Inequality and Threatens Democracy
Cathy O'Neil - 2016
Increasingly, the decisions that affect our lives--where we go to school, whether we can get a job or a loan, how much we pay for health insurance--are being made not by humans, but by machines. In theory, this should lead to greater fairness: Everyone is judged according to the same rules.But as mathematician and data scientist Cathy O'Neil reveals, the mathematical models being used today are unregulated and uncontestable, even when they're wrong. Most troubling, they reinforce discrimination--propping up the lucky, punishing the downtrodden, and undermining our democracy in the process.
Noise: A Flaw in Human Judgment
Daniel Kahneman - 2021
Suppose that different food inspectors give different ratings to indistinguishable restaurants — or that when a company is handling customer complaints, the resolution depends on who happens to be handling the particular complaint. Now imagine that the same doctor, the same judge, the same inspector, or the same company official makes different decisions, depending on whether it is morning or afternoon, or Monday rather than Wednesday. These are examples of noise: variability in judgments that should be identical. In Noise, Daniel Kahneman, Cass R. Sunstein, and Olivier Sibony show how noise contributes significantly to errors in all fields, including medicine, law, economic forecasting, police behavior, food safety, bail, security checks at airports, strategy, and personnel selection. And although noise can be found wherever people make judgments and decisions, individuals and organizations alike are commonly oblivious to the role of chance in their judgments and in their actions. Drawing on the latest findings in psychology and behavioral economics, and the same kind of diligent, insightful research that made Thinking, Fast and Slow and Nudge groundbreaking New York Times bestsellers, Noise explains how and why humans are so susceptible to noise in judgment — and what we can do about it.
Randomistas: How Radical Researchers Changed Our World
Andrew Leigh - 2018
Investigating everything from jails to ad campaigns, philanthropy to schools, the randomistas are building evidence and busting myths.Randomised tests are carried out on us every day: by supermarkets, search engines, online dating sites and direct marketers. Political parties use randomised trials to win elections. But how do these tests work? Are there any ethical issues? And what do they reveal about our choices?In Randomistas, Andrew Leigh tells the stories of radical researchers who overturned conventional wisdom in medicine, politics, economics, law enforcement and more. From finding the cure to scurvy to discovering what policies really improve literacy rates, randomistas have shaped life as we know it – but they often had to fight to conduct their trials and have their findings implemented.In the tradition of Malcolm Gladwell, Randomistas is a brilliant and entertaining exploration of a hidden but vital foundation of modern life.
Big Data: Does Size Matter?
Timandra Harkness - 2016
It can help us do things faster and more efficiently than ever before, from tracking wolves through Minnesota by GPS to predicting which crimes are likely to happen where. Mega data has led to scientific and social achievements that would have been impossible just a few years ago. But being too dazzled by the scale, the speed, and the geeky jargon can lead us astray. It's big, but it's not always clever.Timandra Harkness cuts through the hype to put data science into its real-life context using a wide range of stories, people, and places to reveal what is essentially a human science--demystifying big data, telling us where it comes from and what it can do. BIG DATA then asks the awkward questions: What are the unspoken assumptions underlying its methods? Are we being bamboozled by mega data's size, its speed, and its shiny technology?Nobody needs a degree in computer science to follow Harkness's exploration of what mega data can do for us--and what it can't or shouldn't. BIG DATA asks you to decide: Are you a data point, or a human being?
Nudge: Improving Decisions About Health, Wealth, and Happiness
Richard H. Thaler - 2008
Thaler, and Cass R. Sunstein: a revelatory look at how we make decisionsNew York Times bestsellerNamed a Best Book of the Year by The Economist and the Financial Times Every day we make choices—about what to buy or eat, about financial investments or our children’s health and education, even about the causes we champion or the planet itself. Unfortunately, we often choose poorly. Nudge is about how we make these choices and how we can make better ones. Using dozens of eye-opening examples and drawing on decades of behavioral science research, Nobel Prize winner Richard H. Thaler and Harvard Law School professor Cass R. Sunstein show that no choice is ever presented to us in a neutral way, and that we are all susceptible to biases that can lead us to make bad decisions. But by knowing how people think, we can use sensible “choice architecture” to nudge people toward the best decisions for ourselves, our families, and our society, without restricting our freedom of choice.
A Whole New Mind: Why Right-Brainers Will Rule the Future
Daniel H. Pink - 2004
A Whole New Mind takes readers to a daring new place, and a provocative and necessary new way of thinking about a future that's already here.
The Shape of the New: Four Big Ideas and How They Made the Modern World
Scott L. Montgomery - 2015
Yet these ideas also hold contradictions. They have been used in the service of brutal systems such as slavery and colonialism, been appropriated and twisted by monsters like Stalin and Hitler, and provoked reactions against the Enlightenment’s legacy by Islamic Salafists and the Christian Religious Right.The Shape of the New argues that it is impossible to understand the ideological and political conflicts of our own time without familiarizing ourselves with the history and internal tensions of these world-changing ideas. With passion and conviction, it exhorts us to recognize the central importance of these ideas as historical forces and pillars of the Western humanistic tradition. It makes the case that to read the works of the great thinkers is to gain invaluable insights into the ideas that have shaped how we think and what we believe.
No One Would Listen
Harry Markopolos - 2010
The only book to tell the story of Madoff's scam and the SEC's failings by those who saw both first hand
Describes how Madoff was enabled by investors and fiduciaries alike
Discusses how the SEC missed the red flags raised by Markopolos
Despite repeated written and verbal warnings to the SEC by Harry Markopolos, Bernie Madoff was allowed to continue his operations. No One Would Listen paints a vivid portrait of Markopolos and his determined team of financial sleuths, and what impact Madoff's scam will have on financial markets and regulation for decades to come.