They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    Now you can relieve your worst IBS symptoms by adopting a low FODMAP diet. FODMAPs are simple carbohydrates that can be the hidden culprits behind digestive disorders. The Low FODMAP 28-Day Plan, from New York Times and Amazon best-selling publisher Rockridge Press, is a straightforward 4-week plan for removing FODMAPs from your diet and banishing digestive pain forever. With easy guidelines and simple recipes, you’ll learn how to identify and avoid FODMAP foods, and make healthy and delicious FODMAP free meals in your own kitchen. With The Low FODMAP 28-Day Plan you will soothe your digestive system and make it easy to enjoy meals again, with:•105 recipes for delicious, nutritious low FODMAP dishes including Huevos Rancheros, Maple-Soy Glazed Salmon, Butterscotch Pudding, and Spiced Popcorn •A “symptom tracker” so you can log what you’re eating and how it affects your symptoms •An easy-to-follow quickstart guide to help you begin a low FODMAP diet •Comprehensive lists of foods to enjoy or avoid based on their FODMAP content, •10 tips for sticking to a low FODMAP diet when dining out

    The new edition is thoroughly updated, including most notably a new chapter on innate immunity, a capstone chapter on immune responses in time and space, and many new focus boxes drawing attention to exciting clinical, evolutionary, or experimental connections that help bring the material to life.See what's in the LaunchPad

    Its organization and thoroughness are unsurpassed, putting it above similar review books. Students who thoroughly read this book should have no trouble successfully completing their psychiatry clerkship and passing the shelf exam. As course director for the core psychiatry clerkship at my institution, I will recommend this book to students."--Doody's Review Service"First Aid for the Psychiatry Clerkship" gives you the core information needed to impress on the wards and pass the psychiatry clerkship exam. Written by students who know what it takes to succeed, and based on the national guidelines for the psychiatry clerkship, the book is filled with mnemonics, ward and exam tips, tables, clinical images, algorithms, and newly added mini-cases.Features Completely revised based on the psychiatry clerkship's core competencies Written by medical students who passed and reviewed by faculty for accuracy NEW integrated mini-cases illustrate classic patient presentations and/or commonly tested scenarios NEW illustrations and management algorithms Updated throughout with enhanced sections on medications, depression/anxiety, and child psychiatry Helps students hone in on the most important concepts for the clerkship and the examThe content you need to ace the clerkship: Section I: How to Succeed in the Psychiatry Clerkship Section II: High-Yield Facts; Examination and Diagnosis; Psychotic Disorders; Mood Disorders; Anxiety and Adjustment Disorders; Personality Disorders; Substance-Related Disorders; Cognitive Disorders; Geriatric Disorders; Psychiatric Disorders in Children; Dissociative Disorders; Somataform and Factitious Disorders; Impulse Control Disorders; Eating Disordes; Disorders; Sleep Disorders; Sexual Disorders; Psychtherapies; Psychopharmacology; Legal Issues; Section III: Awards and Opportunities.

    Second, it proposes that the inhabitants of this subterranean biosphere are not plants or animals as we know them, but heat-loving bacteria that survive on a diet consisting solely of hydrocarbons that is, natural gas and petroleum. And third and perhaps most heretically, the book advances the stunning idea that most hydrocarbons on Earth are not the byproduct of biological debris ("fossil fuels"), but were a common constituent of the materials from which the earth itself was formed some 4.5 billion years ago.The implications are astounding. The theory proposes answers to often-asked questions: Is the deep hot biosphere where life originated, and do Mars and other seemingly barren planets contain deep biospheres? Even more provocatively, is it possible that there is an enormous store of hydrocarbons upwelling from deep within the earth that can provide us with abundant supplies of gas and petroleum?However far-fetched these ideas seem, they are supported by a growing body of evidence, and by the indisputable stature and seriousness Gold brings to any scientific debate. In this book we see a brilliant and boldly original thinker, increasingly a rarity in modern science, as he develops potentially revolutionary ideas about how our world works.

    Integrated central case studies woven throughout each chapter, use real-life stories to give you a tangible and engaging framework around which to learn and understand the science behind environmental issues. Printed on FSC (Forest Stewardship Council) certified paper, the newly revised Fourth Edition engages you through the addition of new EnvisionIt photo essays.

    The fastest-growing segment of the population, those beyond the age of fifty, are no longer content to simply cope with the losses of age. Mental acuity and vitality are becoming a life-long pursuit. Now, the science of the mind is catching up with the Baby Boom generation. In this landmark book, renowned psychiatrist Gene Cohen challenges the long-held belief that our brain power inevitably declines as we age, and shows that there are actually positive changes taking place in our minds. Based on the latest studies of the brain, as well as moving stories of men and women in the second half of life, The Mature Mind reveals for the first time how we can continue to grow and flourish. Cohen's groundbreaking theory-the first to elaborate on the psychology of later life-describes how the mind gives us "inner pushes" and creates new opportunities for positive change throughout adult life. He shows how we can jump-start that growth at any age and under any circumstances, fine-tuning as we go, actively building brain reserves and new possibilities. The Mature Mind offers a profoundly different and intriguing look at ourselves, challenging old assumptions, raising bold new questions, and providing exciting answers grounded in science and the realities of everyday life.

    The text teaches the basics of solving problems using its trademark clear discussions and new art-enhanced format. The text moves students beyond rote quantitative problem solving, encouraging them to visualize and think about a problem before beginning to solve it; it conveys the key concepts being discussed to help students truly understand the chemistry by using unique, proven features. The clean, interesting writing style talks directly to students with a minimum of distractions. Molecular illustrations are abundant and are placed where they are referenced for maximum effectiveness with students. The well-integrated McMurry/Fay media program includes the IRCD, PH GradeAssist, a CW/CD suite and more.

    Part One presents the general principles of pathophysiology and discusses the influence of the environment and the role of genetics in the development of disease. Part Two, organized by body system, examines normal anatomy and physiology, alterations of function in adults, and alterations of function in children.

    Full of advice on how surgeons should use their heads as well as their hands - how to think, plan, and improvise - when, for example, operating on a massively bleeding trauma patient. Starts with general principles, continues with specific injuries to abdomen, chest, neck, and peripheral vessels. Generously illustrated throughout, with drawings produced specifically for this book. For residents, general surgeons with an interest in trauma, and for surgeons operating on badly wounded patients in isolated military, rural, or humanitarian settings. Asher Hirshberg and Kenneth L Mattox are trauma surgeons at the Ben Taub General Hospital, Houston, and professors at the Michael E DeBakey Department of Surgery, Baylor College of Medicine, Houston, USA. Kenneth L Maddox is famous as the lead editor of McGraw Hill's classic text, Trauma, now in its fifth edition. This is going to be a GREAT book!

    It strikes a balance between theory and application by incorporating real-world examples; helping students visualize the three-dimensional atomic and molecular structures that are the basis of chemical activity; and developing problem-solving and critical thinking skills. Although the fifth edition incorporates many new features, such as macro to micro artwork, six new animations correlated to the text, and the addition of new hand-sketched worked examples, General Chemistry is still 200 to 300 pages shorter and much less expensive than other two-semester textbooks. Dr. Chang's concise-but-thorough approach will appeal to efficiency-minded instructors and value-conscious students.

    Pulitzer Prize–winning author Siddhartha Mukherjee, a leading cancer physician and researcher, selects the year’s top science and nature writing from journalists who dive into their fields with curiosity and passion, delivering must-read articles from a wide array of fields.

    Acclaimed Fearless Critic Robin Goldstein has gone around the country serving 6,000 glasses of wine from brown paper bags to experts and everyday wine drinkers around America. Here, in print for the first time, are the shocking results, including full-page reviews of the 100 wines that beat $50 to $150 bottles in the blind tastings.

    This book will show you that you do not have to be born with a silver spoon, come from royalty, become a celebrity or date the richest guy in the world to become elegant. The book contains practical tips and tricks on how to achieve elegance without the need for stylists, a walk-in closet and all the fancy things we think we need to be elegant. It will help you understand what works for you, what will feel good for you and what is suitable for the different roles that you play in life.