In this gripping account, David Quammen takes the reader along on this astonishing quest to learn how, where from, and why these diseases emerge and asks the terrifying question: What might the next big one be?

    Mona Hanna-Attisha, alongside a team of researchers, parents, friends, and community leaders, discovered that the children of Flint, Michigan, were being exposed to lead in their tap water--and then battled her own government and a brutal backlash to expose that truth to the world. At the center of the story is Dr. Mona herself--an immigrant, doctor, scientist, and mother whose family's activist roots inspired her pursuit of justice.What the Eyes Don't See is a riveting account of a shameful disaster that became a tale of hope, the story of a city on the ropes that came together to fight for justice, self-determination, and the right to build a better world for their--and all of our--children.

    As he would later write in the first of a series of award-winning columns for "Vanity Fair," he suddenly found himself being deported "from the country of the well across the stark frontier that marks off the land of malady." Over the next eighteen months, until his death in Houston on December 15, 2011, he wrote constantly and brilliantly on politics and culture, astonishing readers with his capacity for superior work even in extremis.Throughout the course of his ordeal battling esophageal cancer, Hitchens adamantly and bravely refused the solace of religion, preferring to confront death with both eyes open. In this account of his affliction, he describes the torments of illness, discusses its taboos, and explores how disease transforms experience and changes our relationship to the world around us. By turns personal and philosophical, Hitchens embraces the full panoply of human emotions as cancer invades his body and compels him to grapple with the enigma of mortality.

    Though he never left Italy, his inventions and discoveries were heralded around the world. Most sensationally, his telescopes allowed him to reveal a new reality in the heavens and to reinforce the astounding argument that the Earth moves around the Sun. For this belief, he was brought before the Holy Office of the Inquisition, accused of heresy, and forced to spend his last years under house arrest. Of Galileo's three illegitimate children, the eldest best mirrored his own brilliance, industry, and sensibility, and by virtue of these qualities became his confidante. Born Virginia in 1600, she was thirteen when Galileo placed her in a convent near him in Florence, where she took the most appropriate name of Suor Maria Celeste. Her loving support, which Galileo repaid in kind, proved to be her father's greatest source of strength throughout his most productive and tumultuous years. Her presence, through letters which Sobel has translated from their original Italian and masterfully woven into the narrative, graces her father's life now as it did then. Galileo's Daughter dramatically recolors the personality and accomplishment of a mythic figure whose seventeenth-century clash with Catholic doctrine continues to define the schism between science and religion. Moving between Galileo's grand public life and Maria Celeste's sequestered world, Sobel illuminates the Florence of the Medicis and the papal court in Rome during the pivotal era when humanity's perception of its place in the cosmos was being overturned. In that same time, while the bubonic plague wreaked its terrible devastation and the Thirty Years' War tipped fortunes across Europe, one man sought to reconcile the Heaven he revered as a good Catholic with the heavens he revealed through his telescope. With all the human drama and scientific adventure that distinguished Longitude, Galileo's Daughter is an unforgettable story.

    You can’t help but fall for Chika. A page-turner that will no doubt become a classic.” --Mary Karr, author of The Liars’ Club and The Art of Memoir From the #1 New York Times bestselling author of Tuesdays With Morrie comes Mitch Albom’s most personal story to date: an intimate and heartwarming memoir about what it means to be a family and the young Haitian orphan whose short life would forever change his heart.  Chika Jeune was born three days before the devastating earthquake that decimated Haiti in 2010. She spent her infancy in a landscape of extreme poverty, and when her mother died giving birth to a baby brother, Chika was brought to The Have Faith Haiti Orphanage that Albom operates in Port Au Prince. With no children of their own, the forty-plus children who live, play, and go to school at the orphanage have become family to Mitch and his wife, Janine. Chika’s arrival makes a quick impression. Brave and self-assured, even as a three-year-old, she delights the other kids and teachers. But at age five, Chika is suddenly diagnosed with something a doctor there says, “No one in Haiti can help you with.” Mitch and Janine bring Chika to Detroit, hopeful that American medical care can soon return her to her homeland. Instead, Chika becomes a permanent part of their household, and their lives, as they embark on a two-year, around-the-world journey to find a cure. As Chika’s boundless optimism and humor teach Mitch the joys of caring for a child, he learns that a relationship built on love, no matter what blows it takes, can never be lost. Told in hindsight, and through illuminating conversations with Chika herself, this is Albom at his most poignant and vulnerable. Finding Chika is a celebration of a girl, her adoptive guardians, and the incredible bond they formed—a devastatingly beautiful portrait of what it means to be a family, regardless of how it is made.

    None of this felt right; and as she got older, she longed for more stories that allowed disability to be complex and ordinary, uncomfortable and fine, painful and fulfilling.Writing about the rhythms and textures of what it means to live in a body that doesn’t fit, Rebekah reflects on everything from the complications of kindness and charity, living both independently and dependently, experiencing intimacy, and how the pervasiveness of ableism in our everyday media directly translates to everyday life.Disability affects all of us, directly or indirectly, at one point or another. By exploring this truth in poignant and lyrical essays, Taussig illustrates the need for more stories and more voices to understand the diversity of humanity. Sitting Pretty challenges us as a society to be patient and vigilant, practical and imaginative, kind and relentless, as we set to work to write an entirely different story.

    David Starr Jordan was a taxonomist, a man possessed with bringing order to the natural world. In time, he would be credited with discovering nearly a fifth of the fish known to humans in his day. But the more of the hidden blueprint of life he uncovered, the harder the universe seemed to try to thwart him. His specimen collections were demolished by lightning, by fire, and eventually by the 1906 San Francisco earthquake—which sent more than a thousand of his discoveries, housed in fragile glass jars, plummeting to the floor. In an instant, his life’s work was shattered. Many might have given up, given in to despair. But Jordan? He surveyed the wreckage at his feet, found the first fish he recognized, and confidently began to rebuild his collection. And this time, he introduced one clever innovation that he believed would at last protect his work against the chaos of the world. When NPR reporter Lulu Miller first heard this anecdote in passing, she took Jordan for a fool—a cautionary tale in hubris, or denial. But as her own life slowly unraveled, she began to wonder about him. Perhaps instead he was a model for how to go on when all seemed lost. What she would unearth about his life would transform her understanding of history, morality, and the world beneath her feet. Part biography, part memoir, part scientific adventure, Why Fish Don’t Exist reads like a fable about how to persevere in a world where chaos will always prevail.

    What is going on? Anatomy of an Epidemic challenges readers to think through that question themselves. First, Whitaker investigates what is known today about the biological causes of mental disorders. Do psychiatric medications fix “chemical imbalances” in the brain, or do they, in fact, create them? Researchers spent decades studying that question, and by the late 1980s, they had their answer. Readers will be startled—and dismayed—to discover what was reported in the scientific journals. Then comes the scientific query at the heart of this book: During the past fifty years, when investigators looked at how psychiatric drugs affected long-term outcomes, what did they find? Did they discover that the drugs help people stay well? Function better? Enjoy good physical health? Or did they find that these medications, for some paradoxical reason, increase the likelihood that people will become chronically ill, less able to function well, more prone to physical illness?  This is the first book to look at the merits of psychiatric medications through the prism of long-term results. Are long-term recovery rates higher for medicated or unmedicated schizophrenia patients? Does taking an antidepressant decrease or increase the risk that a depressed person will become disabled by the disorder? Do bipolar patients fare better today than they did forty years ago, or much worse? When the National Institute of Mental Health (NIMH) studied the long-term outcomes of children with ADHD, did they determine that stimulants provide any benefit?  By the end of this review of the outcomes literature, readers are certain to have a haunting question of their own: Why have the results from these long-term studies—all of which point to the same startling conclusion—been kept from the public?  In this compelling history, Whitaker also tells the personal stories of children and adults swept up in this epidemic. Finally, he reports on innovative programs of psychiatric care in Europe and the United States that are producing good long-term outcomes. Our nation has been hit by an epidemic of disabling mental illness, and yet, as Anatomy of an Epidemic reveals, the medical blueprints for curbing that epidemic have already been drawn up.

    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

    Confusing messages from health authorities and ineffective treatments have left many people desperate for reliable solutions. An enormous alternative industry is filling the void, selling products that are often of questionable safety and totally unknown effectiveness.In Clean, doctor and journalist James Hamblin explores how we got here, examining the science and culture of how we care for our skin today. He talks to dermatologists, microbiologists, allergists, immunologists, aestheticians, bar-soap enthusiasts, venture capitalists, Amish people, theologians, and straight-up scam artists, trying to figure out what it really means to be clean. He even experiments with giving up showers entirely, and discovers that he is not alone.Along the way he realizes that most of our standards of cleanliness are less related to health than most people think. A major part of the picture has been missing: a little-known ecosystem known as the skin microbiome--the trillions of microbes that live on our skin and in our pores. These microbes are not dangerous; they're more like an outer layer of skin that no one knew we had, and they influence everything from acne, eczema, and dry skin to how we smell. The new goal of skin care will be to cultivate a healthy biome--and to embrace the meaning of "clean" in the natural sense. This can mean doing much less, saving time, money, energy, water, and plastic bottles in the process.Lucid, accessible, and deeply researched, Clean explores the ongoing, radical change in the way we think about our skin, introducing readers to the emerging science that will be at the forefront of health and wellness conversations in coming years.

    Illuminating, completely engaging—it's essential reading for all since we all know someone whose life, family or friends are touched by the disease that directly afflicts a fifth of Canadians. In her early twenties, while outwardly thriving in her dream job and enjoying warm familial support and a strong social network, award-winning journalist Anna Mehler Paperny found herself trapped by feelings of failure and despair. Her first suicide attempt—ingesting a deadly mix of sleeping pills and antifreeze—landed her in the ICU, followed by weeks of enforced detention that ran the gamut of horrifying, boring, hilarious, and absurd. This was Anna's entry into the labyrinthine psychiatric care system responsible for providing care to millions of Canadians.As she struggled to survive the psych ward and as an outpatient—enduring the "survivor's" shame of facing concerned family, friends, and co-workers; finding (or not) the right therapist, the right meds; staying healthy, insured, and employed—Anna could not help but turn her demanding journalist's eye on her condition and on the system in which she found herself. She set off on a quest to "know her enemy," interviewing leading practitioners in the field across Canada and the US—from psychiatrists to neurological experts, brain-mapping pioneers to heroic family practitioners, and others dabbling in novel hypotheses. She reveals in courageously frank detail her own experiences with the pharmacological pitfalls and side effects of long-term treatment, and offers moving case studies of conversations with others, opening wide a window into how we treat (and fail to treat) the disease that accounts for more years swallowed up by disability than any other in the world.

    Willie Parker grew up in the Deep South, lived in a Christian household, and converted to an even more fundamentalist form of Christianity as a young man. But upon reading an interpretation of the Good Samaritan in a sermon by Dr. Martin Luther King, Jr., he realized that in order to be a true Christian, he must show compassion for all women regardless of their needs. In 2009, he stopped practicing obstetrics to focus entirely on providing safe abortions for the women who need help the most—often women in poverty and women of color—and in the hot bed of the pro-choice debate: the South. He soon thereafter traded in his private practice and his penthouse apartment in Hawaii for the life of an itinerant abortion provider, focusing most recently on women in the Deep South. In Life’s Work, Dr. Willie Parker tells a deeply personal and thought-provoking narrative that illuminates the complex societal, political, religious, and personal realities of abortion in the United States from the unique perspective of someone who performs them and defends the right to do so every day. He also looks at how a new wave of anti-abortion activism, aimed at making incremental changes in laws and regulations state by state, are slowly chipping away at the rights of women to control their own lives. In revealing his daily battle against mandatory waiting periods and bogus rules governing the width of hallways, Dr. Parker uncovers the growing number of strings attached to the right to choose and makes a powerful Christian case for championing reproductive rights.

    A year later, he'd completed a solo course from Athens to Marathon, and now, after dozens of such races, not to mention triathlons and a dozen critically acclaimed books, he reflects upon the influence the sport has had on his life and--even more important--on his writing. Equal parts training log, travelogue, and reminiscence, this revealing memoir covers his four-month preparation for the 2005 New York City Marathon and takes us to places ranging from Tokyo's Jingu Gaien gardens, where he once shared the course with an Olympian, to the Charles River in Boston among young women who outpace him. Through this marvelous lens of sport emerges a panorama of memories and insights: the eureka moment when he decided to become a writer, his greatest triumphs and disappointments, his passion for vintage LPs, and the experience, after fifty, of seeing his race times improve and then fall back. By turns funny and sobering, playful and philosophical, What I Talk About When I Talk About Running is rich and revelatory, both for fans of this masterful yet guardedly private writer and for the exploding population of athletes who find similar satisfaction in distance running."

    Based on his own experience and the stories of his patients, Frankl argues that we cannot avoid suffering but we can choose how to cope with it, find meaning in it, and move forward with renewed purpose. At the heart of his theory, known as logotherapy, is a conviction that the primary human drive is not pleasure but the pursuit of what we find meaningful. Man's Search for Meaning has become one of the most influential books in America; it continues to inspire us all to find significance in the very act of living.

    [It] was due the next day. We were out at our family cabin in Bolinas, and he was at the kitchen table close to tears, surrounded by binder paper and pencils and unopened books on birds, immobilized by the hugeness of the task ahead. Then my father sat down beside him, put his arm around my brother's shoulder, and said. 'Bird by bird, buddy. Just take it bird by bird.'"With this basic instruction always in mind, Anne Lamott returns to offer us a new gift: a step-by-step guide on how to write and on how to manage the writer's life. From "Getting Started,' with "Short Assignments," through "Shitty First Drafts," "Character," "Plot," "Dialogue." all the way from "False Starts" to "How Do You Know When You're Done?" Lamott encourages, instructs, and inspires. She discusses "Writers Block," "Writing Groups," and "Publication." Bracingly honest, she is also one of the funniest people alive.If you have ever wondered what it takes to be a writer, what it means to be a writer, what the contents of your school lunches said about what your parents were really like, this book is for you. From faith, love, and grace to pain, jealousy, and fear, Lamott insists that you keep your eyes open, and then shows you how to survive. And always, from the life of the artist she turns to the art of life.