Born and raised in a small town, they enjoy a close relationship, though each has her own tastes and personality. But the Hensels also share a body. Their two heads sit side-by-side on a single torso, with two arms and two legs. They have not only survived, but have developed into athletic, graceful young women. And that, writes Mark S. Blumberg, opens an extraordinary window onto human development and evolution.In Freaks of Nature, Blumberg turns a scientist's eye on the oddities of nature, showing how a subject once relegated to the sideshow can help explain some of the deepest complexities of biology. Why, for example, does a two-headed human so resemble a two-headed minnow? What we need to understand, Blumberg argues, is that anomalies are the natural products of development, and it is through developmental mechanisms that evolution works. Freaks of Nature induces a kind of intellectual vertigo as it upends our intuitive understanding of biology. What really is an anomaly? Why is a limbless human a freak, but a limbless reptile-a snake-a successful variation?What we see as deformities, Blumberg writes, are merely alternative paths for development, which challenge both the creature itself and our ability to fit it into our familiar categories. Rather than mere dead-ends, many anomalies prove surprisingly survivable-as in the case of the goat without forelimbs that learned to walk upright. Blumberg explains how such variations occur, and points to the success of the Hensel sisters and the goat as examples of the extraordinary flexibility inherent in individual development.In taking seriously a subject that has often been shunned as discomfiting and embarrassing, Mark Blumberg sheds new light on how individuals-and entire species-develop, survive, and evolve.

    Serendipity, timing, and luck played a part in the discovery of unintentional cures and breakthroughs:A plastic shard in an RAF pilot’s eye leads to the use of plastic for contact lenses.The inability to remove a titanium chamber from rabbit’s bone leads to dental implants.Viagra was discovered by a group of chemists, working in the lab to find a new drug to alleviate the pain of angina pectoris.A stretch of five weeks of unusually warm weather in 1928 played a role in assisting Dr. Alexander Fleming in his analysis of bacterial growth and the discovery of penicillin.After studying the effects of the venom injected by the bite of a deadly pit viper snake, chemists developed a groundbreaking drug that works to control blood pressure. Accidental Medical Discoveries is an entertaining and enlightening look at the creation of 25 medical inventions that have changed the world – unintentionally. The book is presented in a lively and engaging way, and will appeal to a wide variety of readers, from history buffs to trivia fanatics to those in the medical profession.

    As she sped through the pages, she became enthralled by the intense drama behind the competition to discover the code of life. Even though her high school counselor told her girls didn’t become scientists, she decided she would.Driven by a passion to understand how nature works and to turn discoveries into inventions, she would help to make what the book’s author, James Watson, told her was the most important biological advance since his co-discovery of the structure of DNA. She and her collaborators turned ​a curiosity ​of nature into an invention that will transform the human race: an easy-to-use tool that can edit DNA. Known as CRISPR, it opened a brave new world of medical miracles and moral questions. The development of CRISPR and the race to create vaccines for coronavirus will hasten our transition to the next great innovation revolution. The past half-century has been a digital age, based on the microchip, computer, and internet. Now we are entering a life-science revolution. Children who study digital coding will be joined by those who study genetic code. Should we use our new evolution-hacking powers to make us less susceptible to viruses? What a wonderful boon that would be! And what about preventing depression? Hmmm…Should we allow parents, if they can afford it, to enhance the height or muscles or IQ of their kids? After helping to discover CRISPR, Doudna became a leader in wrestling with these moral issues and, with her collaborator Emmanuelle Charpentier, won the Nobel Prize in 2020.

    He worked with - and relaxed with - scientific giants of that time such as Edward Teller, Enrico Fermi, Stan Ulam, John von Neumann, and John Wheeler, and here offers illuminating insights into the personalities, the strengths, and the quirks of these men. Well known for his ability to explain physics to nonspecialists, Ford also brings to life the physics of fission and fusion and provides a brief history of nuclear science from the discovery of radioactivity in 1896 to the ten-megaton explosion of “Mike” that obliterated a Pacific Island in 1952. Ford worked at both Los Alamos and Princeton's Project Matterhorn, and brings out Matterhorn's major, but previously unheralded contribution to the development of the H bomb. Outside the lab, he drove a battered Chevrolet around New Mexico, a bantam motorcycle across the country, and a British roadster around New Jersey. Part of the charm of Ford's book is the way in which he leavens his well-researched descriptions of the scientific work with brief tales of his life away from weapons.Contents: The Big Idea The Protagonists The Choice The Scientists, the Officials, and the President Nuclear Energy Some Physics Going West A New World The Classical Super Calculating and Testing Constructing Matterhorn Academia Cowers New Mexico, New York, and New Jersey The Garwin Design Climbing Matterhorn It's More Than a Boy Readership: A memoir for general readership in the history of science.Key Features: It contains real physics, clearly presented for non-specialists Combining historical scholarship and his own recollections, the author offers important insights into the people and the work that led to the first H bomb Personal anecdotes enliven the book

    Few, if any, of the most imaginative writers of love stories have or could have envisioned the experiences of this couple.

    Entering a room with stainless-steel tables topped by corpses in body bags is shocking no matter how long you've prepared yourself, but a strange thing happened when Montross met her cadaver. Instead of being disgusted by her, she was utterly intrigued-intrigued by the person the woman once was, humbled by the sacrifice she had made in donating her body to science, fascinated by the strange, unsettling beauty of the human form. They called her Eve. This is the story of Montross and Eve-the student and the subject-and the surprising relationship that grew between them. Body of Work is a mesmerizing, rarely seen glimpse into the day-to-day life of a medical student-yet one that follows naturally in the footsteps of recent highly successful literary renderings of the mysteries of medicine such as Atul Gawande's Complications: A Surgeon's Notes on an Imperfect Science. Christine Montross was a poet long before she became a doctor and brings an uncommon perspective to the emotional difficulty of the first year of medical school-the dispiriting task of remaining clinical and detached while in the anatomy lab and the struggle with the line you've crossed by violating another's body once you leave it. Montross was so affected by her experience with Eve that she undertook to learn more about the history of cadavers and the study of anatomy. She visited an autopsy lab in Ireland and the University of Padua in Italy where Vesalius, a forefather of anatomy, once studied; she learned about body snatchers and grave-robbers and anatomists who practiced their work on live criminals. Her disturbing, often entertaining anecdotes enrich this exquisitely crafted memoir, endowing an eerie beauty to the world of a doctor-in-training. Body of Work is an unforgettable examination of the mysteries of the human body and a remarkable look at our relationship with both the living and the dead.

    The media seized hold of the story and, in the process, helped to launch one of the most devastating health scares ever. In the years to come Wakefield would be revealed as a profiteer in league with class-action lawyers, and he would eventually lose his medical license. Meanwhile, one study after another failed to find any link between childhood vaccines and autism. Yet the myth that vaccines somehow cause developmental disorders lives on. Despite the lack of corroborating evidence, it has been popularized by media personalities such as Oprah Winfrey and Jenny McCarthy and legitimized by journalists who claim that they are just being fair to “both sides” of an issue about which there is little debate. Meanwhile, millions of dollars have been diverted from potential breakthroughs in autism research; families have spent their savings on ineffective “miracle cures"; and declining vaccination rates have led to outbreaks of deadly illnesses like Hib, measles, and whooping cough. Most tragic of all is the increasing number of children dying from vaccine-preventable diseases. In The Panic Virus Seth Mnookin draws on interviews with parents, public-health advocates, scientists, and anti-vaccine activists to tackle a fundamental question: How do we decide what the truth is? The fascinating answer helps explain everything from the persistence of conspiracy theories about 9/11 to the appeal of talk-show hosts who demand that President Obama “prove” he was born in America. The Panic Virus is the ultimate cautionary tale for our time.

    In the seventeenth century, the philosopher Spinoza devoted much of his life's work examining how these emotions supported human survival, yet hundreds of years later the biological roots of what we feel remain a mystery. Leading neuroscientist Antonio Damasio—whose earlier books explore rational behavior and the notion of the self—rediscovers a man whose work ran counter to all the thinking of his day, pairing Spinoza's insights with his own innovative scientific research to help us understand what we're made of, and what we're here for.

    As corporations seek to save money and government agencies aim to increase constituent access, minimum qualifications for the guardians of our nation’s healthcare continue to decline—with deadly consequences. This is a story that has not yet been told, and one that has dangerous repercussions for all Americans.

    

    Michael Mosley'This book is marvellous: buy it, share it, recommend it.... We are fortunate to have dedicated, caring and humble folks such as Doc Morgan on the Critical Care front line. We are even better off when a writer can capture all that this exciting, mad, glorious and even exasperating job means. If you work in healthcare, know somebody that does, or simply inhabit a body then this book is for you: in fact it's critical.' Peter Brindley, Professor of Critical Care Medicine, Anesthesiology, Medical Ethics University of Alberta'Just wonderful. I love the exploration of what it means to survive, at what cost and so on. Such an important factor and it's a real problem with what we do. An old surgeon once told me ‘just because we can, doesn’t mean we should. Operating is the easiest thing in the world, not doing so is incredibly challenging’. A lovely book.' Dr Nikki Stamp FRACS Cardiothoracic and Transplant Surgeon and author of Can You Die of a Broken Heart?‘An illuminating, compassionate insight into the fascinating world of intensive care.’ Leah Hazzard, author of Hard PushedCritical is an intelligent, compelling and profoundly insightful journey into the world of intensive care medicine and the lives of people who have forever been changed by it. Being critically ill means one or more of your vital organs have failed – this could be your lungs, your heart, your kidneys, gut or even your brain. Starting with the first recognised case in which a little girl was saved by intensive care in 1952 in Copenhagen, Matt writes brilliantly about the fascinating history, practices and technology in this newest of all the major medical specialties. Matt guides us around the ICU by guiding us around the body and the different organs, and in this way, we learn not only the stories of many of the patients he’s treated over the years, but also about the various functions different parts of the body.   He draws on his time spent with real patients, on the brink of death, and explains how he and his colleagues fight against the odds to help them live. Happily many of his cases have happy endings, but Matt also writes movingly about those cases which will always remain with him – the cases where the mysteries of the body proved too hard to solve, or diagnoses came too late or made no difference to the outcome.

    In the Gospels there are few people who understand love for Jesus as well as Mary Magdalene, which is the reason she is a prophetess of eucharistic love.This work is an extended meditation on the life of Saint Mary Magdalene, known as the "Apostle to the Apostles" because the Risen Christ appeared to her first and then sent her to announce the Resurrection to the apostles. Based on the biblical texts traditionally associated with Mary Magdalene, this book helps readers to learn from her inspiring example and to enter more deeply into adoration of Jesus Christ truly present in the Blessed Sacrament.In telling the story of Mary Magdalene's profound conversion after the Lord had to expel seven demons from her soul, this book shows how she is a shining witness to the transforming power of an encounter with Jesus Christ. Mary Magdalene is the perfect model for those who have experienced the redeeming love of Christ and who seek to deepen their devotion to him and to the Eucharist.

    of Maryland School of Medicine), offers case histories of the health problems of a dozen long-dead famous figures diagnosed from modern medical perspectives. Illustrations depict patients including the odd-looking Pharaoh Akhenaten, C

    Of the 2,975 questions directed to the candidates for president in early 2008, just six mentioned the words "global warming" or "climate change," the greatest policy challenge facing America. To put that in perspective, three questions mentioned UFOs.Today the world's major unsolved challenges all revolve around science. By the 2012 election cycle, at a time when science is influencing every aspect of modern life, antiscience views from climate-change denial to creationism to vaccine refusal have become mainstream.Faced with the daunting challenges of an environment under siege, an exploding population, a falling economy and an education system slipping behind, our elected leaders are hard at work... passing resolutions that say climate change is not real and astrology can control the weather.Shawn Lawrence Otto has written a behind-the-scenes look at how the government, our politics, and the media prevent us from finding the real solutions we need. Fool Me Twice is the clever, outraged, and frightening account of America's relationship with science -- a relationship that is on the rocks at the very time we need it most.

    Much more commonly, they are linked to sensory deprivation, intoxication, illness, or injury. People with migraines may see shimmering arcs of light or tiny, Lilliputian figures of animals and people. People with failing eyesight, paradoxically, may become immersed in a hallucinatory visual world. Hallucinations can be brought on by a simple fever or even the act of waking or falling asleep, when people have visions ranging from luminous blobs of color to beautifully detailed faces or terrifying ogres. Those who are bereaved may receive comforting “visits” from the departed. In some conditions, hallucinations can lead to religious epiphanies or even the feeling of leaving one’s own body. Humans have always sought such life-changing visions, and for thousands of years have used hallucinogenic compounds to achieve them. As a young doctor in California in the 1960s, Oliver Sacks had both a personal and a professional interest in psychedelics. These, along with his early migraine experiences, launched a lifelong investigation into the varieties of hallucinatory experience. Here, with his usual elegance, curiosity, and compassion, Dr. Sacks weaves together stories of his patients and of his own mind-altering experiences to illuminate what hallucinations tell us about the organization and structure of our brains, how they have influenced every culture’s folklore and art, and why the potential for hallucination is present in us all, a vital part of the human condition.