Professors are asked to consider their demise and to ruminate on what matters most to them: What wisdom would we impart to the world if we knew it was our last chance? If we had to vanish tomorrow, what would we want as our legacy?When Randy Pausch, a computer science professor at Carnegie Mellon, was asked to give such a lecture, he didn't have to imagine it as his last, since he had recently been diagnosed with terminal cancer. But the lecture he gave, 'Really Achieving Your Childhood Dreams', wasn't about dying. It was about the importance of overcoming obstacles, of enabling the dreams of others, of seizing every moment (because time is all you have and you may find one day that you have less than you think). It was a summation of everything Randy had come to believe. It was about living.In this book, Randy Pausch has combined the humour, inspiration, and intelligence that made his lecture such a phenomenon and given it an indelible form. It is a book that will be shared for generations to come.

    I have loved and been loved. I have been given much and I have given something in return. Above all, I have been a sentient being, a thinking animal, on this beautiful planet, and that in itself has been an enormous privilege and adventure.” —Oliver SacksNo writer has succeeded in capturing the medical and human drama of illness as honestly and as eloquently as Oliver Sacks. During the last few months of his life, he wrote a set of essays in which he movingly explored his feelings about completing a life and coming to terms with his own death. “It is the fate of every human being,” Sacks writes, “to be a unique individual, to find his own path, to live his own life, to die his own death.”Together, these four essays form an ode to the uniqueness of each human being and to gratitude for the gift of life.

    Beth spends her days riding the buses in her Pennsylvania city. The drivers, a lively group, are her mentors; her fellow passengers are her community. One day, Beth asked Rachel to accompany her on the buses for an entire year; the book is the chronicle of that remarkable time. Rachel, a writer and college teacher whose hyperbusy life camouflaged her emotional isolation, had much to learn in her sister's extraordinary world. Here are life lessons from which every reader can profit: how to live in the moment, how to pay attention to what really matters, how to change, how to love, —and how to slow down and enjoy the ride. Simon elegantly braids together riveting memories of terrifying maternal abandonment, fierce sisterly loyalty, and astonishing forgiveness. She brings to light the almost invisible world of mental retardation, finds unlikely heroes in everyday life, and portrays her very special sister Beth as the endearing and indomitable person she is. This heartwarming book takes the reader on an inspirational journey, at once unique and universal.

    Leslie Jamison deftly excavates the stories we tell about addiction--both her own and others'--and examines what we want these stories to do, and what happens when they fail us.All the while, she offers a fascinating look at the larger history of the recovery movement, and at the literary and artistic geniuses whose lives and works were shaped by alcoholism and substance dependence, including John Berryman, Jean Rhys, Raymond Carver, Billie Holiday, David Foster Wallace, and Denis Johnson, as well as brilliant figures lost to obscurity but newly illuminated here.For the power of her striking language and the sharpness of her piercing observations, Jamison has been compared to such iconic writers as Joan Didion and Susan Sontag. Yet her utterly singular voice also offers something new. With enormous empathy and wisdom, Jamison has given us nothing less than the story of addiction and recovery in America writ large, a definitive and revelatory account that will resonate for years to come.

    At age twenty-four, Hornbacher was diagnosed with Type I rapid-cycle bipolar, the most severe form of bipolar disorder.In Madness, in her trademark wry and utterly self-revealing voice, Hornbacher tells her new story. Through scenes of astonishing visceral and emotional power, she takes us inside her own desperate attempts to counteract violently careening mood swings by self-starvation, substance abuse, numbing sex, and self-mutilation. How Hornbacher fights her way up from a madness that all but destroys her, and what it is like to live in a difficult and sometimes beautiful life and marriage -- where bipolar always beckons -- is at the center of this brave and heart-stopping memoir.Madness delivers the revelation that Hornbacher is not alone: millions of people in America today are struggling with a variety of disorders that may disguise their bipolar disease. And Hornbacher's fiercely self-aware portrait of her own bipolar as early as age four will powerfully change, too, the current debate on whether bipolar in children actually exists.Ten years after Kay Redfield Jamison's An Unquiet Mind, this storm of a memoir will revolutionize our understanding of bipolar disorder.

    Dr. Eben Alexander was one of those scientists. A highly trained neurosurgeon, Alexander knew that NDEs feel real, but are simply fantasies produced by brains under extreme stress.Then, Dr. Alexander’s own brain was attacked by a rare illness. The part of the brain that controls thought and emotion—and in essence makes us human—shut down completely. For seven days he lay in a coma. Then, as his doctors considered stopping treatment, Alexander’s eyes popped open. He had come back.Alexander’s recovery is a medical miracle. But the real miracle of his story lies elsewhere. While his body lay in coma, Alexander journeyed beyond this world and encountered an angelic being who guided him into the deepest realms of super-physical existence. There he met, and spoke with, the Divine source of the universe itself.Alexander’s story is not a fantasy. Before he underwent his journey, he could not reconcile his knowledge of neuroscience with any belief in heaven, God, or the soul. Today Alexander is a doctor who believes that true health can be achieved only when we realize that God and the soul are real and that death is not the end of personal existence but only a transition.This story would be remarkable no matter who it happened to. That it happened to Dr. Alexander makes it revolutionary. No scientist or person of faith will be able to ignore it. Reading it will change your life.

    Armstrong writes about her experience as one of only a few people to participate in an experimental treatment for depression involving ten rounds of a chemically induced coma approximating brain death.For years, Heather B. Armstrong has alluded to her struggle with depression on her website. But in 2016, Heather found herself in the depths of a depression she just couldn’t shake, an episode darker and longer than anything she had previously experienced. This book recalls the torturous eighteen months of suicidal depression she endured and the month-long experimental study in which doctors used propofol anesthesia to quiet all brain activity for a full fifteen minutes before bringing her back from a flatline. Ten times. The experience wasn’t easy. Not for Heather or her family. But a switch was flipped, and Heather hasn’t experienced a single moment of suicidal depression since. The Valedictorian of Being Dead brings to light a groundbreaking new treatment for depression.

    Around the time Elizabeth Gilbert turned thirty, she went through an early-onslaught midlife crisis. She had everything an educated, ambitious American woman was supposed to want—a husband, a house, a successful career. But instead of feeling happy and fulfilled, she was consumed with panic, grief, and confusion. She went through a divorce, a crushing depression, another failed love, and the eradication of everything she ever thought she was supposed to be. To recover from all this, Gilbert took a radical step. In order to give herself the time and space to find out who she really was and what she really wanted, she got rid of her belongings, quit her job, and undertook a yearlong journey around the world—all alone. Eat, Pray, Love is the absorbing chronicle of that year. Her aim was to visit three places where she could examine one aspect of her own nature set against the backdrop of a culture that has traditionally done that one thing very well. In Rome, she studied the art of pleasure, learning to speak Italian and gaining the twenty-three happiest pounds of her life. India was for the art of devotion, and with the help of a native guru and a surprisingly wise cowboy from Texas, she embarked on four uninterrupted months of spiritual exploration. In Bali, she studied the art of balance between worldly enjoyment and divine transcendence. She became the pupil of an elderly medicine man and also fell in love the best way—unexpectedly. An intensely articulate and moving memoir of self-discovery, Eat, Pray, Love is about what can happen when you claim responsibility for your own contentment and stop trying to live in imitation of society’s ideals. It is certain to touch anyone who has ever woken up to the unrelenting need for change.

    And that's what Furiously Happy is all about."Jenny’s readings are standing room only, with fans lining up to have Jenny sign their bottles of Xanax or Prozac as often as they are to have her sign their books. Furiously Happy appeals to Jenny's core fan base but also transcends it. There are so many people out there struggling with depression and mental illness, either themselves or someone in their family—and in Furiously Happy they will find a member of their tribe offering up an uplifting message (via a taxidermied roadkill raccoon). Let's Pretend This Never Happened ostensibly was about embracing your own weirdness, but deep down it was about family. Furiously Happy is about depression and mental illness, but deep down it's about joy—and who doesn't want a bit more of that?

    Operations on the brain carry grave risks. Every day, leading neurosurgeon Henry Marsh must make agonizing decisions, often in the face of great urgency and uncertainty.If you believe that brain surgery is a precise and exquisite craft, practiced by calm and detached doctors, this gripping, brutally honest account will make you think again. With astonishing compassion and candor, Marsh reveals the fierce joy of operating, the profoundly moving triumphs, the harrowing disasters, the haunting regrets, and the moments of black humor that characterize a brain surgeon's life.Do No Harm provides unforgettable insight into the countless human dramas that take place in a busy modern hospital. Above all, it is a lesson in the need for hope when faced with life's most difficult decisions.

    At nine he started working on an original theory in astrophysics that experts believe may someday put him in line for a Nobel Prize, and at age twelve he became a paid researcher in quantum physics. But the story of Kristine’s journey with Jake is all the more remarkable because his extraordinary mind was almost lost to autism. At age two, when Jake was diagnosed, Kristine was told he might never be able to tie his own shoes. The Spark is a remarkable memoir of mother and son. Surrounded by “experts” at home and in special ed who tried to focus on Jake’s most basic skills and curtail his distracting interests—moving shadows on the wall, stars, plaid patterns on sofa fabric—Jake made no progress, withdrew more and more into his own world, and eventually stopped talking completely. Kristine knew in her heart that she had to make a change. Against the advice of her husband, Michael, and the developmental specialists, Kristine followed her instincts, pulled Jake out of special ed, and began preparing him for mainstream kindergarten on her own. Relying on the insights she developed at the daycare center she runs out of the garage in her home, Kristine resolved to follow Jacob’s “spark”—his passionate interests. Why concentrate on what he couldn’t do? Why not focus on what he could? This basic philosophy, along with her belief in the power of ordinary childhood experiences (softball, picnics, s’mores around the campfire) and the importance of play, helped Kristine overcome huge odds. The Barnetts were not wealthy people, and in addition to financial hardship, Kristine herself faced serious health issues. But through hard work and determination on behalf of Jake and his two younger brothers, as well as an undying faith in their community, friends, and family, Kristine and Michael prevailed. The results were beyond anything anyone could have imagined. Dramatic, inspiring, and transformative, The Spark is about the power of love and courage in the face of overwhelming obstacles, and the dazzling possibilities that can occur when we learn how to tap the true potential that lies within every child, and in all of us.

    Not long after, she also became mute. Her tenacious struggle to overcome these handicaps-with the help of her inspired teacher, Anne Sullivan-is one of the great stories of human courage and dedication. In this classic autobiography, first published in 1903, Miss Keller recounts the first 22 years of her life, including the magical moment at the water pump when, recognizing the connection between the word "water" and the cold liquid flowing over her hand, she realized that objects had names. Subsequent experiences were equally noteworthy: her joy at eventually learning to speak, her friendships with Oliver Wendell Holmes, Edward Everett Hale and other notables, her education at Radcliffe (from which she graduated cum laude), and-underlying all-her extraordinary relationship with Miss Sullivan, who showed a remarkable genius for communicating with her eager and quick-to-learn pupil.

    A self-confessed workaholic, she regularly put 'knife before life', knowing it was all going to be worth it because it would lead to her longed-for career.But if the punishing hours in surgery weren't hard enough, she also faced challenges as a young female surgeon navigating a male-dominated specialty. She was regularly left to carry out complex procedures without senior surgeons' oversight; she was called all sorts of things, from 'emotional' to 'too confident'; and she was expected to work a relentless on-call roster - sometimes seventy hours a week or more - to prove herself.Eventually it was too much and Yumiko quit.Emotional Female is her account of what it was like to train in the Australian public hospital system, and what made her walk away.Yumiko Kadota is a voice for her generation when it comes to burnout and finding the resilience to rebuild after suffering a physical, emotional and existential breakdown. This is a brave, honest and unflinching work from a major new talent.

    This was supposed to be a story of how Chinese parents are better at raising kids than Western ones. But instead, it's about a bitter clash of cultures, a fleeting taste of glory, and how I was humbled by a thirteen-year-old." —Amy ChuaAll decent parents want to do what's best for their children. What Battle Hymn of the Tiger Mother reveals is that the Chinese just have a totally different idea of how to do that. Western parents try to respect their children's individuality, encouraging them to pursue their true passions and providing a nurturing environment. The Chinese believe that the best way to protect your children is by preparing them for the future and arming them with skills, strong work habits, and inner confidence. Battle Hymn of the Tiger Mother chronicles Chua's iron-willed decision to raise her daughters, Sophia and Lulu, her way—the Chinese way—and the remarkable results her choice inspires.Here are some things Amy Chua would never allow her daughters to do:- have a playdate- be in a school play- complain about not being in a school play- not be the #1 student in every subject except gym and drama- play any instrument other than the piano or violin- not play the piano or violinThe truth is Lulu and Sophia would never have had time for a playdate. They were too busy practicing their instruments (two to three hours a day and double sessions on the weekend) and perfecting their Mandarin.Of course no one is perfect, including Chua herself. Witness this scene:"According to Sophia, here are three things I actually said to her at the piano as I supervised her practicing:- Oh my God, you're just getting worse and worse.- I'm going to count to three, then I want musicality.- If the next time's not PERFECT, I'm going to take all your stuffed animals and burn them!"But Chua demands as much of herself as she does of her daughters. And in her sacrifices—the exacting attention spent studying her daughters' performances, the office hours lost shuttling the girls to lessons—the depth of her love for her children becomes clear. Battle Hymn of the Tiger Mother is an eye-opening exploration of the differences in Eastern and Western parenting—and the lessons parents and children everywhere teach one another.

    Five years after he married Kristen, the love of his life, they learn that he has Asperger syndrome. The diagnosis explains David’s ever-growing list of quirks and compulsions, his lifelong propensity to quack and otherwise melt down in social exchanges, and his clinical-strength inflexibility. But it doesn’t make him any easier to live with.Determined to change, David sets out to understand Asperger syndrome and learn to be a better husband—no easy task for a guy whose inability to express himself rivals his two-year-old daughter's, who thinks his responsibility for laundry extends no further than throwing things in (or at) the hamper, and whose autism-spectrum condition makes seeing his wife's point of view a near impossibility.Nevertheless, David devotes himself to improving his marriage with an endearing yet hilarious zeal that involves excessive note-taking, performance reviews, and most of all, the Journal of Best Practices: a collection of hundreds of maxims and hard-won epiphanies that result from self-reflection both comic and painful. They include "Don’t change the radio station when she's singing along," "Apologies do not count when you shout them," and "Be her friend, first and always." Guided by the Journal of Best Practices, David transforms himself over the course of two years from the world’s most trying husband to the husband who tries the hardest, the husband he’d always meant to be.Filled with humor and surprising wisdom, The Journal of Best Practices is a candid story of ruthless self-improvement, a unique window into living with an autism-spectrum condition, and proof that a true heart can conquer all.