Adam Brochert, MD-who scored in the 99th percentile on the Step 2 USMLE-and Theodore X. O'Connell, MD-author of several review and clinical reference books-present essential questions and answers covering the important concepts you need to know to score well on the USMLE Step 2 exam: key conditions you will be expected to recognize, all specialty and subspecialty topics, and necessary clinical concepts.Learn the most important questions and answers with the proven format of the highly acclaimed Secrets Series.Master all specialty and subspecialty topics covered on Step 2.Identify key facts and secrets using the Top 100 Secrets chapter.Review material quickly and easily thanks to bulleted lists, algorithms, and illustrations.Apply the pearls, tips, memory aids, and secrets from well-known and highly popular authors, Adam Brochert, MD and Theodore X. O'Connell, MD. Find information quickly with a second color highlighting chapter and section titles, legends, bullets and icons, and key terms.Consult the book wherever you go thanks to the portable size that fits in your lab coat pocket.

    Rochman takes an authoritative look at the latest hot-button issues in the world of pre- and postnatal testing and tells the stories of women and men struggling to understand the variety of tests and grappling with their results—revelations that are sometimes joyous, sometimes heartbreaking, and often profound.Propelled by human narratives and meticulously reported, The Gene Machine introduces us to scientists working to unlock the secrets of the human genome; gene counselors and spiritual advisers helping parents manage this complex new reality; and, of course, parents themselves, including the author, who glimpse the genetic futures of their children. The Gene Machine is both a scientific road map and a meditation on our power to shape the future, one that gets to the very core of what it means to be human.

    In three successive waves, from 1918 to 1919, influenza killed more than 50 million people. German soldiers termed it Blitzkatarrh, British soldiers referred to it as Flanders Grippe, but world-wide, the pandemic gained the notorious title of “Spanish Flu." Nowhere on earth escaped: the United States recorded 550,000 deaths (five times its total military fatalities in the war), while European deaths totaled more than two million.Amid the war, some governments suppressed news of the outbreak. Even as entire battalions were decimated, with both the Allies and the Germans suffering massive casualties, the details of many servicemen’s deaths were hidden to protect public morale. Meanwhile, civilian families were being struck down in their homes. Philadelphia ran out of gravediggers and coffins, and mass burial trenches had to be excavated with steam shovels. Spanish flu conjured up the specter of the Black Death of 1348 and the great plague of 1665, while the medical profession, shattered after five terrible years of conflict, lacked the resources to contain and defeat this new enemy. Through primary and archival sources, historian Catharine Arnold gives readers the first truly global account of this terrible epidemic.

    From wild baboons to gooey slime molds, most every living organism instinctually knows how to balance their diets, except modern-day humans. When and why did we lose this ability, and how can we get it back? David Raubenheimer and Stephen Simpson reveal the answers to these questions in a gripping tale of evolutionary biology and nutritional science, based upon years of groundbreaking research. Their colorful scientific journey takes readers across the globe, from the foothills of Cape Town, to the deserts of Arizona, to a state-of-the-art research center in Sydney. Readers will encounter locusts, mice and even gorillas along the way as the scientists test their hypotheses on various members of the animal kingdom. This epic scientific adventure culminates in a unifying theory of nutrition that has profound implications for our current epidemic of metabolic diseases and obesity. Raubenheimer and Simpson ultimately offer useful advice to understand the unwanted side effects of fad diets, gain control over one’s food environment, and see that delicious and healthy are integral parts of proper eating.

    Ruggieri's Confessions of a Surgeon and Atul Gawande's Better -- a pioneering surgeon shares memories from a life in one of surgery’s most demanding fields The 1980s marked a revolution in the field of organ transplants, and Bud Shaw, M.D., who studied under Tom Starzl in Pittsburgh, was on the front lines. Now retired from active practice, Dr. Shaw relays gripping moments of anguish and elation, frustration and reward, despair and hope in his struggle to save patients. He reveals harshly intimate moments of his medical career: telling a patient's husband that his wife has died during surgery; struggling to complete a twenty-hour operation as mental and physical exhaustion inch closer and closer; and flying to retrieve a donor organ while the patient waits in the operating room. Within these more emotionally charged vignettes are quieter ones, too, like growing up in rural Ohio, and being awakened late at night by footsteps in the hall as his father, also a surgeon, slipped out of the house to attend to a patient in the ER. In the tradition of Mary Roach, Jerome Groopman, Eric Topol, and Atul Gawande, Last Night in the OR is an exhilarating, fast-paced, and beautifully written memoir, one that will captivate readers with its courage, intimacy, and honesty.

    The cold winter air triggered a coughing fit, and she began to choke. She was choking on a lot that day. A sick child. A pending divorce. The guilt of failing as a partner and as a mother. When the coughing finally stopped, she thought it was over. She could not have been more wrong.When she coughed that morning, a small tear ripped through her dura mater, the membrane covering the brain and spinal cord. But she didn’t know that yet. Instead, Andrea went on with her day, unaware that her cerebrospinal fluid was already beginning to leak out of that tiny opening.What followed was nine months of pain and confusion as her brain, no longer cushioned by a healthy waterbed of fluid, sank in her skull. At a time in her life when she needed to be as clear-thinking as possible?as a writer, as a mother, as a woman attempting to strike out on her own after two decades of marriage?she was plagued by cognitive impairment and constant pain, trapped by her own brain—all while mystifying doctors and pushing the limits of medical understanding.In this luminous and moving narrative, Andrea reveals the astonishing story of this tumultuous year—her fraught search for treatment; how patients, especially women, fight to be seen as reliable narrators of their own experiences; and how her life-altering recovery process affected both her and her family.The mind-brain connection is one of the greatest mysteries of the human condition. In some folklore, the cerebrospinal fluid around the brain is thought to be the place where consciousness actually begins. Here, in the pages of The Beginning of Everything, Andrea seeks to understand: Where was “I” when I wasn’t there?

    In Bones, orthopedic surgeon Roy A. Meals explores and extols this amazing material that both supports and records vertebrate life.Inside the body, bone proves itself the world’s best building material. Meals examines the biological makeup of bones; demystifies how they grow, break, and heal; and compares the particulars of human bone to variations throughout the animal kingdom. In engaging and clear prose, he debunks familiar myths—humans don’t have exactly 206 bones—and illustrates common bone diseases, like osteoporosis and arthritis, and their treatments. Along the way, he highlights the medical innovations—from the first X-rays to advanced operative techniques—that enhance our lives and introduces the giants of orthopedic surgery who developed them.After it has supported vertebrate life, bone reveals itself in surprising ways—sometimes hundreds of millions of years later. With enthusiasm and humor, Meals investigates the diverse roles bone has played in human culture throughout history. He highlights allusions to bone in religion and literature, from Adam’s rib to Hamlet’s skull, and uncovers its enduring presence as fossils, technological tools, and musical instruments ranging from the Tibetan thighbone kangling horn to everyday drumsticks. From the dawn of civilization through to the present day, humankind has repurposed bone to serve and protect, and even to teach, amuse, and inspire.Approachable and entertaining, Bones richly illuminates our bodies’ essential framework.

    But after falling backwards into the specialty, Dr. Fulkerson found neurosurgery to be a field filled with joy, sadness, a little humor, and courageous and inspiring patients.In an honest and compelling retelling of his long and winding road to train and then practice as a pediatric neurosurgeon, Dr. Fulkerson guides others through his journey from medical school to service on a small military base, through residency training, and finally, to a practice in a highly specialized children's hospital. The journey reveals the dramatic swings of emotions experienced by both patients and doctors in an increasingly hostile medical environment. Dr. Fulkerson also shares stories of dedicated professors who train medical students and resident surgeons to care for the tiniest neurosurgical patients.Nothing Good Happens at ... The Baby Hospital offers a compelling glimpse into the joys, tragedies, and hopeful moments that surround the highly specialized and sometimes silly world of pediatric neurosurgery.

    It determines if you gain or lose weight, if you’re feeling energetic or fatigued, if you’re upbeat or depressed. In this essential guide and cookbook, Drew Ramsey, MD, explores the role the human brain plays in every part of your life, including mood, health, focus, memory, and appetite, and reveals what foods you need to eat to keep your brain—and by extension your body—properly fueled.Drawing upon cutting-edge scientific research, Dr. Ramsey identifies the twenty-one nutrients most important to brain health and overall well-being—the very nutrients that are often lacking in most people’s diets. Without these nutrients, he emphasizes, our brains and bodies don’t run the way they should.Eat Complete includes 100 appetizing, easy, gluten-free recipes engineered for optimal nourishment. It also teaches readers how to use food to correct the nutrient deficiencies causing brain drain and poor health for millions. For example:• Start the day with an Orange Pecan Waffle or a Turmeric Raspberry Almond Smoothie, and the Vitamin E found in the nuts will work to protect vulnerable brain fat (plus the fiber keeps you satisfied until lunch).• Enjoy Garlic Butter Shrimp over Zucchini Noodles and Mussels with Garlicky Kale Ribbons and Artichokes, and the zinc and magnesium from the seafood will help stimulate the growth of new brain cells.• Want to slow down your brain’s aging process? Indulge with a cup of Turmeric Cinnamon Hot Chocolate, and the flavanols found in chocolate both increase blood flow to the brain and help fight age-related memory decline.Featuring fifty stunning, full-color photographs, Eat Complete helps you pinpoint the nutrients missing from your diet and gives you tasty recipes to transform your health—and ultimately your life.

    With the latest findings about the mental and physical benefits of exercise, personal stories from scientists and laypeople alike, as well as researched-based prescriptions for readers, Gretchen Reynolds shows what kind of exercise—and how much—is necessary to stay healthy, get fit, and attain a smaller jeans size. Inspired by Reynolds's wildly popular “Phys Ed” column for The New York Times, this book explains how exercise affects the body in distinct ways and provides the tools readers need to achieve their fitness goals, whether that's a faster 5K or staying trim.

    The subject of a documentary film, an NPR feature, an ABC News piece, and a widely syndicated New York Times obituary, Martha enjoyed life, and people. From within her iron lung, she graduated first in her class in high school and at Wake Forest University, and was elected to Phi Beta Kappa. She was determined to be a writer and, with her devoted mother taking dictation, she became a journalist--but had to give up her career when her father became ill. Still, Martha created for herself a vast and radiant world--holding dinner parties with the table pushed right up to her iron lung, voraciously reading, running her own household, and caring for her mother when she became ill with Alzheimer's and increasingly abusive to Martha. When voice-activated computers became available, Martha wrote Breath, in part as a tribute to her mother. "This book is her story," writes Anne Rivers Siddons in her preface, "told in the rich words of a born writer. That she told it is a gift to everyone who will read it. That she told it is also as near to a miracle as most are likely to encounter."

    The Lady and Her Monsters by Roseanne Motillo brings to life the fascinating times, startling science, and real-life horrors behind Mary Shelley’s gothic masterpiece, Frankenstein.Montillo recounts how—at the intersection of the Romantic Age and the Industrial Revolution—Shelley’s Victor Frankenstein was inspired by actual scientists of the period: curious and daring iconoclasts who were obsessed with the inner workings of the human body and how it might be reanimated after death.With true-life tales of grave robbers, ghoulish experiments, and the ultimate in macabre research—human reanimation—The Lady and Her Monsters is a brilliant exploration of the creation of Frankenstein, Mary Shelley’s horror classic.

    But this is not the whole story.Shedding light on controversial research and investigating the ferocious gender wars in biology, psychology and anthropology, Angela Saini takes readers on an eye-opening journey to uncover how women are being rediscovered. She explores what these revelations mean for us as individuals and as a society, revealing an alternative view of science in which women are included, rather than excluded.

    Few people can imagine living in a world where such situations are part of everyday life. Yet for London Ambulance Paramedic Lysa Walder, these and thousands of other emergency calls are part of a day's work—scenes of tragedy, loss, and horror—but also stories of triumph and humor, and all the results of an urgent 999 call to the biggest and busiest free ambulance service in the world. Here, she tells the inside story behind the screaming sirens and flashing blue lights of the emergency services and reveals what it's really like to work in a job that frequently brings paramedic teams face-to-face with death—and destiny.

    Concerns over health affected the founding fathers and their families as it did slaves, merchants, immigrants, and everyone else in North America. As both victims of illness and national leaders, the Founders occupied a unique position regarding the development of public health in America. Revolutionary Medicine refocuses the study of the lives of George and Martha Washington, Benjamin Franklin, Thomas Jefferson, John and Abigail Adams, and James and Dolley Madison away from the usual lens of politics to the unique perspective of sickness, health, and medicine in their era. For the founders, republican ideals fostered a reciprocal connection between individual health and the "health" of the nation. Studying the encounters of these American founders with illness and disease, as well as their viewpoints about good health, not only provides us with a richer and more nuanced insight into their lives, but also opens a window into the practice of medicine in the eighteenth century, which is at once intimate, personal, and first hand. Perhaps most importantly, today's American public health initiatives have their roots in the work of America's founders, for they recognized early on that government had compelling reasons to shoulder some new responsibilities with respect to ensuring the health and well-being of its citizenry. The state of medicine and public healthcare today is still a work in progress, but these founders played a significant role in beginning the conversation that shaped the contours of its development. Jeanne E. Abrams is Professor at Penrose Library and the Center for Judaic Studies at the University of Denver. She is the author of Jewish Women Pioneering the Frontier Trail: A History in the American West (NYU Press 2006) and Dr. Charles David Spivak: A Jewish Immigrant and the American Tuberculosis Movement, as well as numerous articles in the fields of American, Jewish and medical history which have appeared in scholarly journals and popular magazines."Revolutionary Medicine is a 'must-read' for anyone interested in the birth of America. Upon closing Jeanne E. Abrams's wonderful book about the illnesses and health experiences of the nation's founders, you will never be able to look at Washington, Adams, Jefferson, and their peers the same way again."—Howard Markel, author of An Anatomy of an Addiction"We know their vaunted place in history: Presidents Washington, Adams, Jefferson, and Madison, and statesman, scientist, and pamphleteer Benjamin Franklin. But it’s their work in public health—and their personal battles with illness—that makes this blend of political and medical history so engaging...Abrams’s meticulous medical portrait of colonial times—and its most powerful leaders—will be fascinating reading for students of both history and medicine."—Publishers Weekly