With exclusive insights from the show’s co-creator Graeme Manson and science consultant Cosima Herter, The Science of Orphan Black takes you behind the closed doors of the Dyad Institute and inside Neolution. Authors Casey Griffin and Nina Nesseth decode the mysteries of Orphan Black — from the history of cloning, epigenetics, synthetic biology, chimerism, the real diseases on which the clone disease is based, and the transhumanist philosophies of Neolution, to what exactly happens when a projectile pencil is shot through a person’s eye and into their brain.

    The popularity of murder mystery books, TV series, and even board games shows that there is an appetite for death, and the more unusual or macabre the method, the better. With gunshots or stabbings the cause of death is obvious, but poisons are inherently more mysterious. How are some compounds so deadly in such tiny amounts?Agatha Christie used poison to kill her characters more often than any other crime fiction writer. The poison was a central part of the novel, and her choice of deadly substances was far from random; the chemical and physiological characteristics of each poison provide vital clues to the discovery of the murderer. Christie demonstrated her extensive chemical knowledge (much of it gleaned by working in a pharmacy during both world wars) in many of her novels, but this is rarely appreciated by the reader.Written by former research chemist Kathryn Harkup, each chapter takes a different novel and investigates the poison used by the murderer. Fact- and fun-packed, A is for Arsenic looks at why certain chemicals kill, how they interact with the body, and the feasibility of obtaining, administering, and detecting these poisons, both when Christie was writing and today.

    That edition was on the cutting edge of what was then known about the origins and nature of the universe. But the intervening years have seen extraordinary advances in the technology of observing both the micro- and the macrocosmic worlds. These observations have confirmed many of Professor Hawking's theoretical predictions in the first edition of his book, including the recent discoveries of the Cosmic Background Explorer satellite (COBE), which probed back in time to within 300,000 years of the universe's beginning and revealed wrinkles in the fabric of space-time that he had projected. Eager to bring to his original text the new knowledge revealed by these observations, as well as his own recent research, Professor Hawking has prepared a new introduction to the book, written an entirely new chapter on wormholes and time travel, and updated the chapters throughout.

    In captivity, octopuses have been known to identify individual human keepers, raid neighboring tanks for food, turn off lightbulbs by spouting jets of water, plug drains, and make daring escapes. How is it that a creature with such gifts evolved through an evolutionary lineage so radically distant from our own? What does it mean that evolution built minds not once but at least twice? The octopus is the closest we will come to meeting an intelligent alien. What can we learn from the encounter?In Other Minds, Peter Godfrey-Smith, a distinguished philosopher of science and a skilled scuba diver, tells a bold new story of how subjective experience crept into being—how nature became aware of itself. As Godfrey-Smith stresses, it is a story that largely occurs in the ocean, where animals first appeared. Tracking the mind’s fitful development, Godfrey-Smith shows how unruly clumps of seaborne cells began living together and became capable of sensing, acting, and signaling. As these primitive organisms became more entangled with others, they grew more complicated. The first nervous systems evolved, probably in ancient relatives of jellyfish; later on, the cephalopods, which began as inconspicuous mollusks, abandoned their shells and rose above the ocean floor, searching for prey and acquiring the greater intelligence needed to do so. Taking an independent route, mammals and birds later began their own evolutionary journeys.But what kind of intelligence do cephalopods possess? Drawing on the latest scientific research and his own scuba-diving adventures, Godfrey-Smith probes the many mysteries that surround the lineage. How did the octopus, a solitary creature with little social life, become so smart? What is it like to have eight tentacles that are so packed with neurons that they virtually “think for themselves”? What happens when some octopuses abandon their hermit-like ways and congregate, as they do in a unique location off the coast of Australia?By tracing the question of inner life back to its roots and comparing human beings with our most remarkable animal relatives, Godfrey-Smith casts crucial new light on the octopus mind—and on our own.

    Today there are three cats for every dog on the planet, and yet cats remain more mysterious, even to their most adoring owners. Unlike dogs, cats evolved as solitary hunters, and, while many have learned to live alongside humans and even feel affection for us, they still don’t quite get us” the way dogs do, and perhaps they never will. But cats have rich emotional lives that we need to respect and understand if they are to thrive in our company.In Cat Sense, renowned anthrozoologist John Bradshaw takes us further into the mind of the domestic cat than ever before, using cutting-edge scientific research to dispel the myths and explain the true nature of our feline friends. Tracing the cat’s evolution from lone predator to domesticated companion, Bradshaw shows that although cats and humans have been living together for at least eight thousand years, cats remain independent, predatory, and wary of contact with their own kind, qualities that often clash with our modern lifestyles. Cats still have three out of four paws firmly planted in the wild, and within only a few generations can easily revert back to the independent way of life that was the exclusive preserve of their predecessors some 10,000 years ago. Cats are astonishingly flexible, and given the right environment they can adapt to a life of domesticity with their owners—but to continue do so, they will increasingly need our help. If we’re to live in harmony with our cats, Bradshaw explains, we first need to understand their inherited quirks: understanding their body language, keeping their environments—however small—sufficiently interesting, and becoming more proactive in managing both their natural hunting instincts and their relationships with other cats.A must-read for any cat lover, Cat Sense offers humane, penetrating insights about the domestic cat that challenge our most basic assumptions and promise to dramatically improve our pets’ lives—and ours.

    By allowing women to control their fertility, the birth control pill has revolutionized women's lives. Women are going to college, graduating, and entering the workforce in greater numbers than ever before, and there's good reason to believe that the birth control pill has a lot to do with this. But there's a lot more to the pill than meets the eye.Although women go on the pill for a small handful of targeted effects (pregnancy prevention and clearer skin, yay!), sex hormones can't work that way. Sex hormones impact the activities of billions of cells in the body at once, many of which are in the brain. There, they play a role in influencing attraction, sexual motivation, stress, hunger, eating patterns, emotion regulation, friendships, aggression, mood, learning, and more. This means that being on the birth control pill makes women a different version of themselves than when they are off of it. And this is a big deal. For instance, women on the pill have a dampened cortisol spike in response to stress. While this might sound great (no stress!), it can have negative implications for learning, memory, and mood. Additionally, because the pill influences who women are attracted to, being on the pill may inadvertently influence who women choose as partners, which can have important implications for their relationships once they go off it. Sometimes these changes are for the better . . . but other times, they're for the worse. By changing what women's brains do, the pill also has the ability to have cascading effects on everything and everyone that a woman encounters. This means that the reach of the pill extends far beyond women's own bodies, having a major impact on society and the world.This paradigm-shattering book provides an even-handed, science-based understanding of who women are, both on and off the pill. It will change the way that women think about their hormones and how they view themselves. It also serves as a rallying cry for women to demand more information from science about how their bodies and brains work and to advocate for better research. This book will help women make more informed decisions about their health, whether they're on the pill or off of it.

    do it? How should you flip your mattress to get the maximum wear out of it? How does Google search the Internet? How many people should you date before settling down? Believe it or not, math plays a crucial role in answering all of these questions and more.Math underpins everything in the cosmos, including us, yet too few of us understand this universal language well enough to revel in its wisdom, its beauty — and its joy. This deeply enlightening, vastly entertaining volume translates math in a way that is at once intelligible and thrilling. Each trenchant chapter of The Joy of x offers an “aha!” moment, starting with why numbers are so helpful, and progressing through the wondrous truths implicit in π, the Pythagorean theorem, irrational numbers, fat tails, even the rigors and surprising charms of calculus. Showing why he has won awards as a professor at Cornell and garnered extensive praise for his articles about math for the New York Times, Strogatz presumes of his readers only curiosity and common sense. And he rewards them with clear, ingenious, and often funny explanations of the most vital and exciting principles of his discipline.Whether you aced integral calculus or aren’t sure what an integer is, you’ll find profound wisdom and persistent delight in The Joy of x.

    It now has 600,000 to a million page hits daily. Every now and then, Munroe would get emails asking him to arbitrate a science debate. 'My friend and I were arguing about what would happen if a bullet got struck by lightning, and we agreed that you should resolve it . . . ' He liked these questions so much that he started up What If. If your cells suddenly lost the power to divide, how long would you survive? How dangerous is it, really, to be in a swimming pool in a thunderstorm? If we hooked turbines to people exercising in gyms, how much power could we produce? What if everyone only had one soulmate?When (if ever) did the sun go down on the British empire? How fast can you hit a speed bump while driving and live?What would happen if the moon went away?In pursuit of answers, Munroe runs computer simulations, pores over stacks of declassified military research memos, solves differential equations, and consults with nuclear reactor operators. His responses are masterpieces of clarity and hilarity, studded with memorable cartoons and infographics. They often predict the complete annihilation of humankind, or at least a really big explosion. Far more than a book for geeks, WHAT IF: Serious Scientific Answers to Absurd Hypothetical Questions explains the laws of science in operation in a way that every intelligent reader will enjoy and feel much the smarter for having read.

    But its toxic effects on society are plain to see—feeding white nationalism, fueling hatred, endangering lives, and corroding our discourse on everything from sports to intelligence. Even well-intentioned people repeat stereotypes based on “science,” because cutting-edge genetics are hard to grasp—and all too easy to distort. Paradoxically, these misconceptions are multiplying even as scientists make unprecedented discoveries in human genetics—findings that, when accurately understood, are powerful evidence against racism. We’ve never had clearer answers about who we are and where we come from, but this knowledge is sorely needed in our casual conversations about race.How to Argue With a Racist emphatically dismantles outdated notions of race by illuminating what modern genetics actually can and can’t tell us about human difference. We now know that the racial categories still dividing us do not align with observable genetic differences. In fact, our differences are so minute that, most of all, they serve as evidence of our shared humanity.

    Breaking down the symbols themselves, they pose a series of questions: What is energy? What is mass? What has the speed of light got to do with energy and mass? In answering these questions, they take us to the site of one of the largest scientific experiments ever conducted. Lying beneath the city of Geneva, straddling the Franco-Swiss boarder, is a 27 km particle accelerator, known as the Large Hadron Collider. Using this gigantic machine—which can recreate conditions in the early Universe fractions of a second after the Big Bang—Cox and Forshaw will describe the current theory behind the origin of mass.Alongside questions of energy and mass, they will consider the third, and perhaps, most intriguing element of the equation: 'c' - or the speed of light. Why is it that the speed of light is the exchange rate? Answering this question is at the heart of the investigation as the authors demonstrate how, in order to truly understand why E=mc2, we first must understand why we must move forward in time and not backwards and how objects in our 3-dimensional world actually move in 4-dimensional space-time. In other words, how the very fabric of our world is constructed. A collaboration between two of the youngest professors in the UK, Why Does E=mc2? promises to be one of the most exciting and accessible explanations of the theory of relativity in recent years.

    A man's promising fourth date ends in the emergency room. A female lawyer with bipolar disorder experiences the highs and lows of dating. A widower hesitates about introducing his children to his new girlfriend. A divorcée in her seventies looks back at the beauty and rubble of past relationships.These are just a few of the people who tell their stories in Modern Love, Revised and Updated, featuring dozens of the most memorable essays to run in The New York Times "Modern Love" column since its debut in 2004.Some of the stories are unconventional, while others hit close to home. Some reveal the way technology has changed dating forever; others explore the timeless struggles experienced by anyone who has ever searched for love. But all of the stories are, above everything else, honest. Together, they tell the larger story of how relationships begin, often fail, and--when we're lucky--endure.Edited by longtime "Modern Love" editor Daniel Jones and featuring a diverse selection of contributors--including Mindy Hung, Trey Ellis, Ann Hood, Deborah Copaken, Terri Cheney, and more--this is the perfect book for anyone who's loved, lost, stalked an ex on social media, or pined for true romance: In other words, anyone interested in the endlessly complicated workings of the human heart.

    . . and then broke? How would you survive? Could you improve on humanity's original timeline? And how hard would it be to domesticate a giant wombat? With this book as your guide, you'll survive--and thrive--in any period in Earth's history. Bestselling author and time-travel enthusiast Ryan North shows you how to invent all the modern conveniences we take for granted--from first principles. This illustrated manual contains all the science, engineering, art, philosophy, facts, and figures required for even the most clueless time traveler to build a civilization from the ground up. Deeply researched, irreverent, and significantly more fun than being eaten by a saber-toothed tiger, How to Invent Everything will make you smarter, more competent, and completely prepared to become the most important and influential person ever.

    See ISBN 9780465094646History is full of strange animal stories invented by the brightest and most influential, from Aristotle to Disney. But when it comes to understanding animals, we’ve got a long way to go.Whether we’re watching a viral video of romping baby pandas or looking at a picture of penguins ‘holding hands’, we often project our own values – innocence, abstinence, hard work – onto animals. So you’ve probably never considered that moose get drunk and that penguins are notorious cheats.In The Unexpected Truth About Animals Zoologist Lucy unravels many such myths – that eels are born from sand, that swallows hibernate under water, and that bears gave birth to formless lumps that are licked into shape by their mothers – to show that the stories we create reveal as much about us as they do about the animals.Astonishing, illuminating and laugh-out-loud funny.

    Kaku skillfully guides us through the latest innovations in string theory and its latest iteration, M-theory, which posits that our universe may be just one in an endless multiverse, a singular bubble floating in a sea of infinite bubble universes. If M-theory is proven correct, we may perhaps finally find answer to the question, “What happened before the big bang?” This is an exciting and unforgettable introduction into the new cutting-edge theories of physics and cosmology from one of the pre-eminent voices in the field.

    But then we never think about food more than when we are hungry and we never think about life rafts more than when we are thrown overboard.”The Comfort Book is Haig’s life raft: it’s a collection of notes, lists, and stories written over a span of several years that originally served as gentle reminders to Haig’s future self that things are not always as dark as they may seem. Incorporating a diverse array of sources from across the world, history, science, and his own experiences, Haig offers warmth and reassurance, reminding us to slow down and appreciate the beauty and unpredictability of existence.