Nashef tells heart-stopping stories of transplants, bypasses, coronary artery repair, and cardiac arrest. He also delivers humane advice about medical realities rarely observed: the futility of obsessing over diet, the necessity of calculating risks, the role of decision making, the resilience of doctor and patient alike, and the threadbare brilliance of the NHS.Nashef is a magnificently warm and likeable doctor and writer; and he has the best imaginable bedside manner.

    The latest edition offers greatly expanded coverage of directed mutagenesis and protein engineering, therapeutic agents, and genetic engineering of plants. Updated chapters reflect recent developments in biotechnology and the societal issues related to it, such as cloning, gene therapy, and patenting and releasing genetically engineered organisms. Over 480 figures, including 200 that are new in this edition, illustrate all key concepts. "Milestones" summarize important research papers in the history of biotechnology and their effects on the field. As in previous editions, the authors clearly explain all concepts and techniques to provide maximum understanding of the subject, avoiding confusing scientific jargon and excessive detail wherever possible. Each chapter concludes with a summary, references, and review questions. Ideally suited as a text for third- and fourth-year undergraduates as well as graduate students, this book is also an excellent reference for health professionals, scientists, engineers, or attorneys interested in biotechnology.

    It splits the mechanical properties chapter into two separate chapters in order to provide additional and expanded coverage of such topics as fatigue, crack propagation and stress, rupture time, and temperature relationships in creep, to name just a few. In addition, all new topics are accompanied by new problems for a stronger understanding of recent developments in the field.

    Leeuwenhoek proceeded to examine the microscopic activity of his spittle, teeth plaque, and feces, and as the result of his findings the field of bacteriology was born. Some two hundred years later, Wilhelm Conrad Roentgen, a professor of theoretical physics at the University of Wurzburg, invited his wife to his laboratory, asked her to place her hand on an unexposed photographic plate, turned on an electric current, and showed this terrified woman a picture of the bones of her hand. And so came the discovery of the X-ray.This absorbing book is the first to describe these and eight other monumental medical discoveries throughout history, bringing to life the scientific pioneers responsible for them and the excitement, frustrations, and jealousies that surrounded the final achievements. Two distinguished physicians, Meyer Friedman and Gerald W. Friedland, have drawn on their many years of experience as well as on that of world-renowned antiquarian book dealers, physician collectors of old and new medical publications, and medical school professors to single out these medical breakthroughs from thousands of candidates, and, in several cases, to provide information never before available. Their engrossing stories of the ten most significant discoveries will be read with enjoyment by anyone fascinated by the mysteries of medicine.

    This latest book gives you a precise regimen for self-treatment along with extensive information on other resources now available to you.

    Before the invention of photography, artists played an essential role in medical science, recording human anatomy in startlingly direct and often moving images. Over 400 years, beginning with Vesalius, they charted the main systems of the body, made precise studies of living organs, documented embryonic development, and described pathologies. Human Anatomy includes portfolios of the work of 19 great anatomical artists, with concise biographies, and culminates with the Visible Human Project, which uses digital tools to visualize the human body.Praise for Human Anatomy:"From Leonardo da Vinci's exquisite pen-and-ink drawings of the human skeleton to the digital Visible Human Project in its three-dimensional glory, this fascinating book . . . documents more than 500 years of anatomical illustration in living color." -Scientific American

    Manhein assists law enforcement officials across the country in identifying bodies and solving criminal cases. In Trail of Bones, her much-anticipated sequel to The Bone Lady, Manhein reveals the everyday realities of forensic anthropology. Going beyond the stereotypes portrayed on television, this real-life crime scene investigator unveils a gritty, exhausting, exacting, alternately rewarding and frustrating world where teamwork supersedes individual heroics and some cases unfortunately remain unsolved.A natural storyteller, Manhein provides gripping accounts of dozens of cases from her twenty-four-year career. Some of them are famous. She describes her involvement in the hunt for two serial killers who simultaneously terrorized the Baton Rouge, Louisiana, region for years; her efforts to recover the remains of the seven astronauts killed in the Columbia space shuttle crash in 2003; and her ultimately successful struggle to identify the beheaded toddler known for years as Precious Doe. Less well-known but equally compelling are cases involving the remains of a Korean War soldier buried for more than forty years and the mystery of "Mardi Gras Man," who was wearing a string of plastic beads when his body was discovered. Manhein describes how the increased popularity of tattoos has aided her work and how forensic science has labored to expose frauds--including a fake "big foot" track she examined from Louisiana's Kisatchie National Forest. She also shares ambitious plans to create a database of biological and DNA profiles of all of the state's missing and unidentified persons.Possessing both compassion and tenacity, Mary Manhein has an extraordinary gift for telling a life story through bones. Trail of Bones takes readers on an entertaining and educating walk in the shoes of this remarkable scientist who has dedicated her life to providing justice for those no longer able to speak for themselves.

    

    But as he gained the trust of his eccentric coworkers and was promoted to acting COO, Larry was thrust into a nightmare world of scandalous controversy, gruesome practices, and deadly secrets.One secret Larry unearthed was the full, tragic, never-before-heard story of what truly happened to the body of baseball icon and American hero Ted Williams.Compelled by this and other horrific discoveries, Larry began copying documents, taking secret pictures, and ultimately wearing a wire every day at Alcor. He started living two lives—“Alcorian” by day, whistleblower by night.Beyond the senseless animal experiments, beyond the dumping of toxic chemicals and AIDS-contaminated blood into the public sewage system, these people saw themselves as the elite, the immortal saviors of mankind who would lead us into the future. Inside this cultlike mentality, anything seemed justified. Maybe even murder.Then Alcor found out. The death threats began.Fleeing from state to state, Larry was stalked and threatened again and again. They chased him through the streets. They left death threats under his windshield wipers. They terrorized his family. Larry Johnson never wanted to be a whistleblower. But he knows this story must be told.

    The nineteenth century experienced an explosion of epidemics such as cholera and diphtheria, driven by industrialization, urbanization and poor hygiene. In this pre-color-photography era, accurate images were relied upon to teach students and aid diagnosis. The best examples, featured here, are remarkable pieces of art that attempted to elucidate the mysteries of the body, and the successive onset of each affliction. Bizarre and captivating images, including close-up details and revealing cross-sections, make all too clear the fascinations of both doctors and artists of the time. Barnett illuminates the fears and obsessions of a society gripped by disease, yet slowly coming to understand and combat it. The age also saw the acceptance of vaccination and the germ theory, and notable diagrams that transformed public health, such as John Snow's cholera map and Florence Nightingale's pioneering histograms, are included and explained. Organized by disease, "The Sick Rose" ranges from little-known ailments now all but forgotten to the epidemics that shaped the modern age. It is a fascinating "Wunderkammer" of a book that will enthrall artists, students, designers, scientists and the incurably curious everywhere.

    Rothman's acclaimed Modern Epidemiology reflects the remarkable conceptual development of this evolving science and the engagement of epidemiologists with an increasing range of current public health concerns. This landmark work is the most comprehensive and cohesive text on the principles and methods of contemporary epidemiologic research.Coauthored by two leading epidemiologists, with 15 additional contributors, the Second Edition presents a much broader range of concepts and methods than Dr. Rothman's single-authored original edition. Coverage of basic measures and study types is more thorough and includes a new chapter on field methods. New chapters on advanced topics in data analysis, such as hierarchical regression, are also included. A new section covers specific areas of research such as infectious disease epidemiology, ecologic studies, disease surveillance, analysis of vital statistics, screening, clinical epidemiology, environmental and occupational epidemiology, reproductive and perinatal epidemiology, genetic epidemiology, and nutritional epidemiology.

    Poison captures them in all their complexity, describing the many roles they have played in history and culture, science and religion, medicine and murder.

    This book integrates clinical examples throughout each chapter and covers important physiologic concepts. It includes 630 multiple choice questions. It covers topics such as: Regulation of food intake; Mitochondria and molecular motors; Renal function; and, Estrogen receptors.

    In brief, it is concerned with the scientific and technological aspects of the design and manufacture of dosage forms for medicines. An understanding of pharmaceutics is therefore vital to all pharmacists and pharmaceutical scientists who are involved in converting a drug or a potential drug into a medicine that can be delivered safely, efficiently and conveniently to the patient.Professor Aulton's Pharmaceutics has become established as the clearest, most comprehensive textbook on this subject. The book provides pharmacy and pharmaceutical science students with the latest information on all aspects of pharmaceutics.provides a logical, comprehensive account of drug design and manufactureincludes the science of formulation and drug deliverydesigned and written for newcomers to the design of dosage formstwo new chapters on the principles and practice of sterilizationdosage-form design and delivery material thoroughly updatedproduct stability and stability testing of medicinal products section totally rewritten and expanded to include more of the relevant chemistryreflects current and future use of biotechnology products throughoutchanges in our understanding of biopharmaceutics, certain areas of drug delivery and the significance of the solid state all reflectednew page size and designnew photographs of equipment and apparatus

    Organized conceptually around the major fields of medical endeavour - anatomy, physiology, pathology, pharmacology, surgery, obstetrics, psychiatry, pediatrics, and family medicine - this book is an accessible overview of medical history as a vibrant component of social, intellectual, and cultural history, and as a research discipline in its own right.Each chapter begins in antiquity and ends in the twentieth century. Throughout, Duffin shows that alternative interpretations can be found for most elements of our past and that topics of interest can go well beyond 'great men' and 'great discoveries' to include ideas, diseases, patients, institutions, and great mistakes. This approach does not mean that the 'great men' (and women) are neglected; rather they appear in context. Medical disasters such as chloramphenicol and thalidomide, are covered along with the triumphs, and examples from Canada's past, largely ignored in other medical histories, are included. A chapter on methodology, suggestions for further reading with special attention to Canadian sources, and a careful index make it possible to research a specific event or historical debate, or to satisfy a more general curiosity.By presenting the material in a structure that resonates with the broad outlines of medical training, and by focusing on the questions asked most often, this text is a relevant guide for students to the history of the profession they are about to embrace, and for those who would teach them, be they physicians or historians. Duffin's clear and entertaining prose and the many illustrations will help to demystify medicine for general readers and for students in other domains, such as history, philosophy, and sociology.