There have been exhilarating highs and devastating lows, but his love for the practice of neurosurgery has never wavered. Following the publication of his celebrated New York Times bestseller Do No Harm, Marsh retired from his full-time job in England to work pro bono in Ukraine and Nepal. In Admissions, he describes the difficulties of working in these troubled, impoverished countries and the further insights it has given him into the practice of medicine. Marsh also faces up to the burden of responsibility that can come with trying to reduce human suffering. Unearthing memories of his early days as a medical student and the experiences that shaped him as a young surgeon, he explores the difficulties of a profession that deals in probabilities rather than certainties and where the overwhelming urge to prolong life can come at a tragic cost for patients and those who love them. Reflecting on what forty years of handling the human brain has taught him, Marsh finds a different purpose in life as he approaches the end of his professional career and a fresh understanding of what matters to us all in the end.

    And more often than we realize, that face is wearing lipstick. Autism in Heels , an intimate memoir, reveals the woman inside one of autism's most prominent figures, Jennifer O'Toole. At the age of thirty-five, Jennifer was diagnosed with Asperger's syndrome, and for the first time in her life, things made sense. Now, Jennifer exposes the constant struggle between carefully crafted persona and authentic existence, editing the autism script with wit, candor, passion, and power. Her journey is one of reverse-self-discovery not only as an Aspie but--more importantly--as a thoroughly modern woman.Beyond being a memoir, Autism in Heels is a love letter to all women. It's a conversation starter. A game changer. And a firsthand account of what it is to walk in Jennifer's shoes (especially those iconic red stilettos).Whether it's bad perms or body image, sexuality or self-esteem, Jennifer's is as much a human journey as one on the spectrum. Because autism "looks a bit different in pink," most girls and women who fit the profile are not identified, facing years of avoidable anxiety, eating disorders, volatile relationships, self-harm, and stunted independence. Jennifer has been there, too. Autism in Heels takes that message to the mainstream.From her own struggles and self-discovery, she has built an empire of empowerment, inspiring women the world over to realize they aren't mistakes. They are misunderstood miracles.

    Fox.The entire world knows Michael J. Fox as Marty McFly, the teenage sidekick of Doc Brown in Back to the Future; as Alex P. Keaton in Family Ties; as Mike Flaherty in Spin City; and through numerous other movie roles and guest appearances on shows such as The Good Wife and Curb Your Enthusiasm. Diagnosed at age 29, Michael is equally engaged in Parkinson’s advocacy work, raising global awareness of the disease and helping find a cure through The Michael J. Fox Foundation for Parkinson’s Research, the world’s leading non-profit funder of PD science. His two previous bestselling memoirs, Lucky Man and Always Looking Up, dealt with how he came to terms with the illness, all the while exhibiting his iconic optimism. His new memoir reassesses this outlook, as events in the past decade presented additional challenges.In No Time Like the Future: An Optimist Considers Mortality, Michael shares personal stories and observations about illness and health, aging, the strength of family and friends, and how our perceptions about time affect the way we approach mortality. Thoughtful and moving, but with Fox’s trademark sense of humor, his book provides a vehicle for reflection about our lives, our loves, and our losses.Running through the narrative is the drama of the medical madness Fox recently experienced, that included his daily negotiations with the Parkinson’s disease he’s had since 1991, and a spinal cord issue that necessitated immediate surgery. His challenge to learn how to walk again, only to suffer a devastating fall, nearly caused him to ditch his trademark optimism and “get out of the lemonade business altogether.”

    Shimi Kang, psychiatrist, bestselling author of The Dolphin Parent"Jessica's ability to open up about painful things in a way that make them hilarious and beautiful is astounding! This book will make you laugh, make you feel brave and make you feel like you are normal and wonderful just the way you are!" --Aisha Alfa, comedian, Just For LaughsComedians live by the mantra tragedy ] time = comedy--hence Jessica Holmes's refreshing and hilarious new memoir about depression, "the cold sore of the mind." She takes us on her journey-- sometimes laugh-out-loud, sometimes cringe-worthy--from successful performer to someone who was basically living the life of a house cat. She muses aboutthe chicken and the egg of depression and comedy marriage counselling (a.k.a. tattling on your spouse) where jokes come from living on the sofa, which now looks like a tornado hit a 7-Eleven her kids' take on the perks of having a depressed mom: "We don't have to clean up anything. Yesterday the cat barfed and Mom just put a cushion on it and went back to playing on the iPad!" the obnoxiousness of anti-depressant commercials: "I never noticed the ocean before!" Holmes shares her two cents on how to play it cool when your medication makes you hear Kate Hudson's voice, and why you don't sneak elk pepperettes into the movies. It's a validating read for anyone who has suffered from depression a little ("I get sad every January") or a lot ("My psychiatrist doesn't have a name for what I've got") or who just thinks real life calls for levity and understanding.

    She'd been fighting her un-thin body since early childhood, and at 29, she finally hit bottom. No diet could transform her body or her life. With the help of an intuitive eating coach and fitness professionals, she learned how to eat based on her body's instincts and exercise sustainably, without obsessing over calories burned. But, with each thrilling step toward a healthy future, she had to contend with the painful truths of her past. BIG GIRL chronicles Kelsey's journey into self-loathing and disordered eating--and out of it. This is a memoir for anyone who's grappled with a distorted body image, food issues, or a dysfunctional family. It's for late bloomers and the not-yet-bloomed. It's for everyone who's tried and failed and felt like a big, fat, loser. So, basically, everyone.

    Pursuing the idea that human affection could be understood, studied, even measured, Harlow (1905-1981) arrived at his conclusions by conducting research-sometimes beautiful, sometimes horrible-on the primates in his University of Wisconsin laboratory. Paradoxically, his darkest experiments may have the brightest legacy, for by studying "neglect" and its life-altering consequences, Harlow confirmed love's central role in shaping not only how we feel but also how we think. His work sparked a psychological revolution. The more children experience affection, he discovered, the more curious they become about the world: Love makes people smarter. The biography of both a man and an idea, The Measure of Love is a powerful and at times disturbing narrative that will forever alter our understanding of human relationships.

    Now they explore the compulsion through a series of compelling case studies in the vein of Oliver Sacks. With vivid portraits that show us the traits by which you can identify a hoarder's piles on sofas and beds that make the furniture useless, houses that can be navigated only by following small paths called goat trails, vast piles of paper that the hoarders "churn" but never discard, even collections of animals and garbage; Frost and Steketee illuminate the pull that possessions exert on all of us. Whether we're savers, collectors, or compulsive cleaners, very few of us are in fact free of the impulses that drive hoarders to the extremes in which they live. For all of us with complicated relationships to our things, Stuff answers the question of what happens when our stuff starts to own us.

    With his classic Why We Get Sick, Dr. Randolph Nesse helped to establish the field of evolutionary medicine. Now he returns with a book that transforms our understanding of mental disorders by exploring a fundamentally new question. Instead of asking why certain people suffer from mental illness, Nesse asks why natural selection has left us all with fragile minds.Drawing on revealing stories from his own clinical practice and insights from evolutionary biology, Nesse shows how negative emotions are useful in certain situations, yet can become overwhelming. Anxiety protects us from harm in the face of danger, but false alarms are inevitable. Low moods prevent us from wasting effort in pursuit of unreachable goals, but they often escalate into pathological depression. Other mental disorders, such as addiction and anorexia, result from the mismatch between modern environment and our ancient human past. And there are good evolutionary reasons for sexual disorders and for why genes for schizophrenia persist. Taken together, these and many more insights help to explain the pervasiveness of human suffering, and show us new paths for relieving it by understanding individuals as individuals.

    Heralded by Publishers Weekly as one of the best science books of the year, it is a provocative and deeply engaging book that elucidates the ties between a woman's experience of her vagina and her sense of self; her impulses, dreams, and courage; and her role in love and in society in completely new and revelatory ways sure to provoke impassioned conversation.A brilliant and nuanced synthesis of physiology, history, and cultural criticism, Vagina: A New Biography explores the physical, political, and spiritual implications of this startling series of new scientific breakthroughs for women and for society as a whole, from a writer whose conviction and keen intelligence have propelled her works to the tops of bestseller lists, and firmly into the realms of modern classics.

    During this time he has broken into a Space Station with a Swiss army knife, disposed of a live snake while piloting a plane, and been temporarily blinded while clinging to the exterior of an orbiting spacecraft. The secret to Col. Hadfield's success-and survival-is an unconventional philosophy he learned at NASA: prepare for the worst-and enjoy every moment of it. In An Astronaut's Guide to Life on Earth, Col. Hadfield takes readers deep into his years of training and space exploration to show how to make the impossible possible. Through eye-opening, entertaining stories filled with the adrenaline of launch, the mesmerizing wonder of spacewalks, and the measured, calm responses mandated by crises, he explains how conventional wisdom can get in the way of achievement-and happiness. His own extraordinary education in space has taught him some counterintuitive lessons: don't visualize success, do care what others think, and always sweat the small stuff. You might never be able to build a robot, pilot a spacecraft, make a music video or perform basic surgery in zero gravity like Col. Hadfield. But his vivid and refreshing insights will teach you how to think like an astronaut, and will change, completely, the way you view life on Earth-especially your own.

    He traces LSD's path from a promising psychiatric research medicine to a recreational drug sparking hysteria and prohibition. We follow Dr. Hofmann's trek across Mexico to discover sacred plants related to LSD, and listen in as he corresponds with other notable figures about his remarkable discovery. Underlying it all is Dr. Hofmann's powerful conclusion that mystical experience may be our planet's best hope for survival. Whether induced by LSD, meditation, or arising spontaneously, such experiences help us to comprehend "the wonder, the mystery of the divine‹in the microcosm of the atom, in the macrocosm of the spiral nebula, in the seeds of plants, in the body and soul of people." More than sixty years after the birth of Albert Hofmann's problem child, his vision of its true potential is more relevant, and more needed, than ever.

    A neurologist's insightful and compassionate look into the misunderstood world of psychosomatic disorders, told through individual case histories

    It's caused alopecia, bulimia, and drug dependency. And Bryony is sick of it. Keeping silent about her illness has given it a cachet it simply does not deserve, so here she shares her story with trademark wit and dazzling honesty.A hugely successful columnist for the Telegraph, a bestselling author, and a happily married mother of an adorable daughter, Bryony has managed to laugh and live well while simultaneously grappling with her illness. Now it's time for her to speak out. Writing with her characteristic warmth and dark humour, Bryony explores her relationship with her OCD and depression as only she can.Mad Girl is a shocking, funny, unpredictable, heart-wrenching, raw and jaw-droppingly truthful celebration of life with mental illness.

    Mara Altman's volatile and apprehensive relationship with her body has led her to wonder about a lot of stuff over the years. Like, who decided that women shouldn't have body hair? And how sweaty is too sweaty? Also, why is breast cleavage sexy but camel toe revolting? Isn't it all just cleavage? These questions and others like them have led to the comforting and sometimes smelly revelations that constitute Gross Anatomy, an essay collection about what it's like to operate the bags of meat we call our bodies.Divided into two sections, "The Top Half" and "The Bottom Half," with cartoons scattered throughout, Altman's book takes the reader on a wild and relatable journey from head to toe—as she attempts to strike up a peace accord with our grody bits.With a combination of personal anecdotes and fascinating research, Gross Anatomy holds up a magnifying glass to our beliefs, practices, biases, and body parts and shows us the naked truth: that there is greatness in our grossness.

    Doctor, Harvard professor, renowned infectious-disease specialist, anthropologist, the recipient of a MacArthur "genius" grant, world-class Robin Hood, Farmer was brought up in a bus and on a boat, and in medical school found his life’s calling: to diagnose and cure infectious diseases and to bring the lifesaving tools of modern medicine to those who need them most.Mountains Beyond Mountains takes us from Harvard to Haiti, Peru, Cuba, and Russia as Farmer changes minds and practices through his dedication to the philosophy that "the only real nation is humanity"—a philosophy that is embodied in the small public charity he founded, Partners in Health. He enlists the help of the Gates Foundation, George Soros, the U.N.’s World Health Organization, and others in his quest to cure the world. At the heart of this book is the example of a life based on hope, and on an understanding of the truth of the Haitian proverb "Beyond mountains there are mountains": as you solve one problem, another problem presents itself, and so you go on and try to solve that one too.