The public has thus been left to wonder whether he is mad, bad, or both.In THE DANGEROUS CASE OF DONALD TRUMP, twenty-seven psychiatrists, psychologists, and other mental health experts argue that, in Mr. Trump’s case, their moral and civic “duty to warn” America supersedes professional neutrality. They then explore Trump’s symptoms and potentially relevant diagnoses to find a complex, if also dangerously mad, man.Philip Zimbardo and Rosemary Sword, for instance, explain Trump’s impulsivity in terms of “unbridled and extreme present hedonism.” Craig Malkin writes on pathological narcissism and politics as a lethal mix. Gail Sheehy, on a lack of trust that exceeds paranoia. Lance Dodes, on sociopathy. Robert Jay Lifton, on the “malignant normality” that can set in everyday life if psychiatrists do not speak up.His madness is catching, too. From the trauma people have experienced under the Trump administration to the cult-like characteristics of his followers, he has created unprecedented mental health consequences across our nation and beyond.It’s not all in our heads. It’s in his."There will not be a book published this fall more urgent, important, or controversial than The Dangerous Case of Donald Trump...profound, illuminating and discomforting" —Bill Moyers

    Prusiner received a Nobel Prize, the world's most prestigious award for achievement in physiology or medicine. That he was the sole recipient of the award for the year was entirely appropriate, for his struggle to identify the agent responsible for ravaging the brains of animals suffering from scrapie and mad cow disease, and of humans with Creutzfeldt-Jakob disease, had been waged largely alone and in some cases in the face of strenuous disagreement.   In this book, Prusiner tells the remarkable story of his discovery of prions—infectious proteins that replicate and cause disease but surprisingly contain no genetic material—and reveals how superb and meticulous science is actually practiced using talented teams of researchers who persevere. He recounts the frustrations and rewards of years of research and offers fascinating portraits of his peers as they raced to discover the causes of fatal brain diseases. Prusiner’s hypothesis, once considered heresy, now stands as accepted science and the basis for developing diagnoses and eventual cures. He closes with a meditation on the legacy of his discovery: What will it take to cure Alzheimer’s, Parkinson’s, Lou Gehrig’s and other devastating diseases of the brain?

    But now, with revolutionary medical advances, death has become just another serious complication. As a young medical student, Dr. David Casarett was inspired by the story of a two-year-old girl named Michelle Funk. Michelle fell into a creek and was underwater for over an hour. When she was found she wasn’t breathing, and her pupils were fixed and dilated. That drowning should have been fatal. But after three hours of persistent work, a team of doctors and nurses was able to bring her back. It was a miracle. If Michelle could come back after three hours of being dead, what about twelve hours? Or twenty-four? What would it take to revive someone who had been frozen for one thousand years? And what does blurring the line between “life” and “death” mean for society? In Shocked, Casarett chronicles his exploration of the cutting edge of resuscitation and reveals just how far science has come. He begins in the eighteenth century, when early attempts at resuscitation involved public displays of barrel rolling, horseback riding (sort of), and blowing smoke up the patient’s various orifices. He then takes us inside a sophisticated cryonics facility in the Arizona desert, a darkroom full of hibernating lemurs in North Carolina, and a laboratory that puts mice into a state of suspended animation. The result is a spectacular tour of the bizarre world of doctors, engineers, animal biologists, and cryogenics enthusiasts trying to bring the recently dead back to life. Fascinating, thought-provoking, and (believe it or not) funny, Shocked is perfect for those looking for a prequel—and a sequel—to Mary Roach’s Stiff, or for anyone who likes to ponder the ultimate questions of life and death.

    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

    And that's what Furiously Happy is all about."Jenny’s readings are standing room only, with fans lining up to have Jenny sign their bottles of Xanax or Prozac as often as they are to have her sign their books. Furiously Happy appeals to Jenny's core fan base but also transcends it. There are so many people out there struggling with depression and mental illness, either themselves or someone in their family—and in Furiously Happy they will find a member of their tribe offering up an uplifting message (via a taxidermied roadkill raccoon). Let's Pretend This Never Happened ostensibly was about embracing your own weirdness, but deep down it was about family. Furiously Happy is about depression and mental illness, but deep down it's about joy—and who doesn't want a bit more of that?

    David Schneider’s The Invention of Surgery is an in-depth biography of the practice that has leapt forward over the centuries from the dangerous guesswork of ancient Greek physicians through the world-changing “implant revolution” of the twentieth century.The Invention of Surgery explains this dramatic progress and highlights the personalities of the discipline's most dynamic historical figures. It links together the lives of the pioneering scientists who first understood what causes disease, how organs become infected or cancerous, and how surgery could powerfully intercede in people’s lives, and then shows how the rise of surgery intersected with many of the greatest medical breakthroughs of the last century, including the evolution of medical education, the transformation of the hospital from a place of dying to a habitation of healing, the development of antibiotics, and the rise of transistors and polymer science.And as Schneider argues, surgery has not finished transforming; new technologies are constantly reinventing both the practice of surgery and the nature of the objects we are permanently implanting in our bodies. Schneider considers these latest developments, asking “What’s next?” and analyzing how our conception of surgery has changed alongside our evolving ideas of medicine, technology, and our bodies.

    With podcasts like My Favorite Murder and In the Dark, bestsellers like I’ll Be Gone in the Dark and Furious Hours, and TV hits like American Crime Story and Wild Wild Country, the cultural appetite for stories of real people doing terrible things is insatiable.Acclaimed author of The Real Lolita and editor of Women Crime Writers: Eight Suspense Novels of the 1940s & 50s (Library of America) and Troubled Daughters, Twisted Wives (Penguin), Sarah Weinman brings together an exemplary collection of recent true crime tales. She culls together some of the most refreshing and exciting contemporary journalists and chroniclers of crime working today.  Michelle Dean’s “Dee Dee Wanted Her Daughter To Be Sick” went viral when it first published and is the basis for the TV show The Act and Pamela Colloff’s “The Reckoning,” is the gold standard for forensic journalism.  There are 13 pieces in all and as a collection, they showcase writing about true crime across the broadest possible spectrum, while also reflecting what makes crime stories so transfixing and irresistible to the modern reader.

    Kear's biggest concern is choosing a major--until she walks into a doctor's office in midtown Manhattan and gets a life-changing diagnosis. She is going blind, courtesy of an eye disease called retinitis pigmentosa, and has only a decade or so before Lights Out. Instead of making preparations as the doctor suggests, Kear decides to carpe diem and make the most of the vision she has left. She joins circus school, tears through boyfriends, travels the world, and through all these hi-jinks, she keeps her vision loss a secret.When Kear becomes a mother, just a few years shy of her vision's expiration date, she amends her carpe diem strategy, giving up recklessness in order to relish every moment with her kids. Her secret, though, is harder to surrender - and as her vision deteriorates, harder to keep hidden. As her world grows blurred, one thing becomes clear: no matter how hard she fights, she won't win the battle against blindness. But if she comes clean with her secret, and comes to terms with the loss, she can still win her happy ending.Told with humor and irreverence, Now I See You is an uplifting story about refusing to cower at life's curveballs, about the power of love to triumph over fear. But, at its core, it's a story about acceptance: facing the truths that just won't go away, and facing yourself, broken parts and all.

    Unable to stand, barely able to think, he waited for hours in an emergency room before being correctly diagnosed and rushed into surgery. Over the next few days, as he clung to life and the first light of a new year came through his window, he found himself reflecting on the fragility of health, not recognized in America as a human right but without which all rights and freedoms have no meaning.And that was before the pandemic. We have since watched American hospitals, long understaffed and undersupplied, buckling under waves of coronavirus patients. The federal government made matters worse through willful ignorance, misinformation, and profiteering. Our system of commercial medicine failed the ultimate test, and thousands of Americans died.In this eye-opening cri de coeur, Snyder traces the societal forces that led us here and outlines the lessons we must learn to survive. In examining some of the darkest moments of recent history and of his own life, Snyder finds glimmers of hope and principles that could lead us out of our current malaise. Only by enshrining healthcare as a human right, elevating the authority of doctors and medical knowledge, and planning for our children's future can we create an America where everyone is truly free.

    After barely surviving the agony of smallpox themselves, they flouted eighteenth-century medicine by borrowing folk knowledge from African slaves and Eastern women in frantic bids to protect their children. From their heroic struggles stems the modern science of immunology as well as the vaccinations that remain our only hope should the disease ever be unleashed again.Jennifer Lee Carrell transports readers back to the early eighteenth century to tell the tales of Lady Mary Wortley Montagu and Dr. Zabdiel Boylston, two iconoclastic figures who helped save London and Boston from the deadliest disease mankind has known.

    The news is full of archaeology: treasures found (British king under parking lot) and treasures lost (looters, bulldozers, natural disaster, and war). Archaeological research tantalizes us with possibilities (are modern humans really part Neandertal?). Where are the archaeologists behind these stories? What kind of work do they actually do, and why does it matter?Marilyn Johnson’s Lives in Ruins is an absorbing and entertaining look at the lives of contemporary archaeologists as they sweat under the sun for clues to the puzzle of our past. Johnson digs and drinks alongside archaeologists, chases them through the Mediterranean, the Caribbean, and even Machu Picchu, and excavates their lives. Her subjects share stories we rarely read in history books, about slaves and Ice Age hunters, ordinary soldiers of the American Revolution, children of the first century, Chinese woman warriors, sunken fleets, mummies.What drives these archaeologists is not the money (meager) or the jobs (scarce) or the working conditions (dangerous), but their passion for the stories that would otherwise be buried and lost.

    In a facility where poverty and social strife are as much a part of the pathology as any microbe, it is the medical students and interns who are thrust into the searing intimacy that is the doctor-patient relationship. With each chapter, Ofri introduces us to a new medical crisis and a human being with an intricate and compelling history.

    But along the way, the feminist pioneer's searing dissents and steely strength have inspired millions. Notorious RBG: The Life and Times of Ruth Bader Ginsburg, created by the young lawyer who began the Internet sensation and an award-winning journalist, takes you behind the myth for an intimate, irreverent look at the justice's life and work. As America struggles with the unfinished business of gender equality and civil rights, Ginsburg stays fierce. And if you don't know, now you know.

    Then, in 2005, astronomer Mike Brown made the discovery of a lifetime: a tenth planet, Eris, slightly bigger than Pluto. But instead of its resulting in one more planet being added to our solar system, Brown’s find ignited a firestorm of controversy that riled the usually sedate world of astronomy and launched him into the public eye. The debate culminated in the demotion of Pluto from real planet to the newly coined category of “dwarf” planet. Suddenly Brown was receiving hate mail from schoolchildren and being bombarded by TV reporters—all because of the discovery he had spent years searching for and a lifetime dreaming about.Filled with both humor and drama, How I Killed Pluto and Why It Had It Coming is Mike Brown’s engaging first-person account of the most tumultuous year in modern astronomy—which he inadvertently caused. As it guides readers through important scientific concepts and inspires us to think more deeply about our place in the cosmos, it is also an entertaining and enlightening personal story: While Brown sought to expand our understanding of the vast nature of space, his own life was changed in the most immediate, human ways by love, birth, and death. A heartfelt and personal perspective on the demotion of everyone’s favorite farflung planet, How I Killed Pluto and Why It Had It Coming is the book for anyone, young or old, who has ever dreamed of exploring the universe—and who among us hasn’t?

    Your head hurts. You're mildly annoyed as you get the kids ready for school and dress for work yourself. Meanwhile, an epic war is being fought, just below your skin. Millions are fighting and dying for you to be able to complain as you head out the door.So what, exactly, is your immune system?Second only to the human brain in its complexity, it is one of the oldest and most critical facets of life on Earth. Without it, you would die within days. In Immune, Philipp Dettmer, the brains behind the most popular science channel on YouTube, takes readers on a journey through the fortress of the human body and its defenses. There is a constant battle of staggering scale raging within us, full of stories of invasion, strategy, defeat, and noble self-sacrifice. In fact, in the time you've been reading this, your immune system has probably identified and eradicated a cancer cell that started to grow in your body.Each chapter delves into an element of the immune system, including defenses like antibodies and inflammation as well as threats like bacteria, allergies, and cancer, as Dettmer reveals why boosting your immune system is actually nonsense, how parasites sneak their way past your body's defenses, how viruses work, and what goes on in your wounds when you cut yourself.Enlivened by engaging graphics and immersive descriptions, Immune turns one of the most intricate, interconnected, and confusing subjects—immunology—into a gripping adventure through an astonishing alien landscape. Immune is a vital and remarkably fun crash course in what is arguably, and increasingly, the most important system in the body.