Your Inner Fish: a Journey into the 3.5-Billion-Year History of the Human Body


Neil Shubin - 2008
    By examining fossils and DNA, Shubin shows us that our hands actually resemble fish fins, our head is organized like that of a long-extinct jawless fish, and major parts of our genome look and function like those of worms and bacteria.Shubin makes us see ourselves and our world in a completely new light. Your Inner Fish is science writing at its finest-enlightening, accessible, and told with irresistible enthusiasm.

Zoobiquity: The Astonishing Connection Between Human and Animal Health


Barbara Natterson-Horowitz - 2012
    Beginning with the above questions, she began informally researching every affliction that she encountered in humans to learn whether it happened with animals, too. And usually, it did: dinosaurs suffered from brain cancer, koalas can catch chlamydia, reindeer seek narcotic escape in hallucinogenic mushrooms, stallions self-mutilate, and gorillas experience clinical depression. Natterson-Horowitz and science writer Kathryn Bowers have dubbed this pan-species approach to medicine zoobiquity. Here, they present a revelatory understanding of what animals can teach us about the human body and mind, exploring how animal and human commonality can be used to diagnose, treat, and heal patients of all species.

The Future of the Mind: The Scientific Quest to Understand, Enhance, and Empower the Mind


Michio Kaku - 2014
    For the first time in history, the secrets of the living brain are being revealed by a battery of high tech brain scans devised by physicists. Now what was once solely the province of science fiction has become a startling reality. Recording memories, telepathy, videotaping our dreams, mind control, avatars, and telekinesis are not only possible; they already exist. The Future of the Mind gives us an authoritative and compelling look at the astonishing research being done in top laboratories around the world—all based on the latest advancements in neuroscience and physics. One day we might have a "smart pill" that can enhance our cognition; be able to upload our brain to a computer, neuron for neuron; send thoughts and emotions around the world on a "brain-net"; control computers and robots with our mind; push the very limits of immortality; and perhaps even send our consciousness across the universe. Dr. Kaku takes us on a grand tour of what the future might hold, giving us not only a solid sense of how the brain functions but also how these technologies will change our daily lives. He even presents a radically new way to think about "consciousness" and applies it to provide fresh insight into mental illness, artificial intelligence and alien consciousness. With Dr. Kaku's deep understanding of modern science and keen eye for future developments, The Future of the Mind is a scientific tour de force--an extraordinary, mind-boggling exploration of the frontiers of neuroscience.

The Sports Gene: Inside the Science of Extraordinary Athletic Performance


David Epstein - 2013
    In college, I ran against Kenyans, and wondered whether endurance genes might have traveled with them from East Africa. At the same time, I began to notice that a training group on my team could consist of five men who run next to one another, stride for stride, day after day, and nonetheless turn out five entirely different runners. How could this be?We all knew a star athlete in high school. The one who made it look so easy. He was the starting quarterback and shortstop; she was the all-state point guard and high-jumper. Naturals. Or were they?The debate is as old as physical competition. Are stars like Usain Bolt, Michael Phelps, and Serena Williams genetic freaks put on Earth to dominate their respective sports? Or are they simply normal people who overcame their biological limits through sheer force of will and obsessive training?The truth is far messier than a simple dichotomy between nature and nurture. In the decade since the sequencing of the human genome, researchers have slowly begun to uncover how the relationship between biological endowments and a competitor’s training environment affects athleticism. Sports scientists have gradually entered the era of modern genetic research.In this controversial and engaging exploration of athletic success, Sports Illustrated senior writer David Epstein tackles the great nature vs. nurture debate and traces how far science has come in solving this great riddle. He investigates the so-called 10,000-hour rule to uncover whether rigorous and consistent practice from a young age is the only route to athletic excellence.Along the way, Epstein dispels many of our perceptions about why top athletes excel. He shows why some skills that we assume are innate, like the bullet-fast reactions of a baseball or cricket batter, are not, and why other characteristics that we assume are entirely voluntary, like an athlete’s will to train, might in fact have important genetic components.This subject necessarily involves digging deep into sensitive topics like race and gender. Epstein explores controversial questions such as:Are black athletes genetically predetermined to dominate both sprinting and distance running, and are their abilities influenced by Africa’s geography?Are there genetic reasons to separate male and female athletes in competition?Should we test the genes of young children to determine if they are destined for stardom?Can genetic testing determine who is at risk of injury, brain damage, or even death on the field?Through on-the-ground reporting from below the equator and above the Arctic Circle, revealing conversations with leading scientists and Olympic champions, and interviews with athletes who have rare genetic mutations or physical traits, Epstein forces us to rethink the very nature of athleticism.

Inheritance: How Our Genes Change Our Lives—and Our Lives Change Our Genes


Sharon Moalem - 2014
    Inheritance Conventional wisdom dictates that our genetic destiny is fixed at conception. But Dr. Moalem's groundbreaking book shows us that the human genome is far more fluid and fascinating than your ninth grade biology teacher ever imagined. By bringing us to the bedside of his unique and complex patients, he masterfully demonstrates what rare genetic conditions can teach us all about our own health and well-being. In the brave new world we're rapidly rocketing into, genetic knowledge has become absolutely crucial. Inheritance provides an indispensable roadmap for this journey by teaching you: -Why you may have recovered from the psychological trauma caused by childhood bullying-but your genes may remain scarred for life. -How fructose is the sugar that makes fruits sweet-but if you have certain genes, consuming it can buy you a one-way trip to the coroner's office. -Why ingesting common painkillers is like dosing yourself repeatedly with morphine-if you have a certain set of genes. -How insurance companies legally use your genetic data to predict the risk of disability for you and your children-and how that impacts the coverage decisions they make for your family. -How to have the single most important conversation with your doctor-one that can save your life. And finally: -Why people with rare genetic conditions hold the keys to medical problems affecting millions. In this trailblazing book, Dr. Moalem employs his wide-ranging and entertaining interdisciplinary approach to science and medicine-- explaining how art, history, superheroes, sex workers, and sports stars all help us understand the impact of our lives on our genes, and our genes on our lives. Inheritance will profoundly alter how you view your genes, your health--and your life.

An Elegant Defense: The Extraordinary New Science of the Immune System: A Tale in Four Lives


Matt Richtel - 2019
    An epic, first-of-its-kind book, entwining leading-edge scientific discovery with the intimate stories of four individual lives, by the Pulitzer Prize–winning New York Times journalist.A terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats.For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders.Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”

An Appetite for Wonder: The Making of a Scientist


Richard Dawkins - 2013
    But what were the influences that shaped his life and intellectual development? And who inspired him to become the pioneering scientist and public thinker now famous (and infamous to some) around the world?In An Appetite for Wonder we join him on a personal journey back to an enchanting childhood in colonial Africa. There the exotic natural world was his constant companion. Boarding school in England at the age of eight, and, later, public school at Oundle introduce Dawkins, and the reader, to strange rules and eccentric schoolmasters, vividly described with both humorous affection and some reservation. An initial fervent attachment to Church of England religion soon gives way to disaffection and, later, teenage rebellion. Early signs of a preference for music, poetry and reading over practical matters become apparent as he recalls the opportunities that entered his small world.Oxford, however, is the catalyst to his life. Vigorous debate in the dynamic Zoology Department unleashes his innate intellectual curiosity, and inspirational mentors together with his own creative thinking ignite the spark that results in his radical new vision of Darwinism, The Selfish Gene.From innocent child to charismatic world-famous scientist, Richard Dawkins paints a colourful, richly textured canvas of his early life. Honest self-reflection and witty anecdotes are interspersed with touching reminiscences of his family and friends, literature, poetry and songs. We are finally able to understand the private influences that shaped the public man who, more than anyone else in his generation, explained our own origins.

Biology


Neil A. Campbell - 1987
    This text has invited more than 4 million students into the study of this dynamic and essential discipline.The authors have restructured each chapter around a conceptual framework of five or six big ideas. An Overview draws students in and sets the stage for the rest of the chapter, each numbered Concept Head announces the beginning of a new concept, and Concept Check questions at the end of each chapter encourage students to assess their mastery of a given concept. New Inquiry Figures focus students on the experimental process, and new Research Method Figures illustrate important techniques in biology. Each chapter ends with a Scientific Inquiry Question that asks students to apply scientific investigation skills to the content of the chapter.

Cure: A Journey into the Science of Mind Over Body


Jo Marchant - 2016
    Recently, however, serious scientists from a range of fields have been uncovering evidence that our thoughts, emotions and beliefs can ease pain, heal wounds, fend off infection and heart disease and even slow the progression of AIDS and some cancers.In Cure, award-winning science writer Jo Marchant travels the world to meet the physicians, patients and researchers on the cutting edge of this new world of medicine. We learn how meditation protects against depression and dementia, how social connections increase life expectancy and how patients who feel cared for recover from surgery faster. We meet Iraq war veterans who are using a virtual arctic world to treat their burns and children whose ADHD is kept under control with half the normal dose of medication. We watch as a transplant patient uses the smell of lavender to calm his hostile immune system and an Olympic runner shaves vital seconds off his time through mind-power alone.Drawing on the very latest research, Marchant explores the vast potential of the mind's ability to heal, lays out its limitations and explains how we can make use of the findings in our own lives. With clarity and compassion, Cure points the way towards a system of medicine that treats us not simply as bodies but as human beings.

How Doctors Think


Jerome Groopman - 2007
    In that short time, many doctors decide on the likely diagnosis and best treatment. Often, decisions made this way are correct, but at crucial moments they can also be wrong -- with catastrophic consequences. In this myth-shattering book, Jerome Groopman pinpoints the forces and thought processes behind the decisions doctors make. Groopman explores why doctors err and shows when and how they can -- with our help -- avoid snap judgments, embrace uncertainty, communicate effectively, and deploy other skills that can profoundly impact our health. This book is the first to describe in detail the warning signs of erroneous medical thinking and reveal how new technologies may actually hinder accurate diagnoses. How Doctors Think offers direct, intelligent questions patients can ask their doctors to help them get back on track.Groopman draws on a wealth of research, extensive interviews with some of the country’s best doctors, and his own experiences as a doctor and as a patient. He has learned many of the lessons in this book the hard way, from his own mistakes and from errors his doctors made in treating his own debilitating medical problems.How Doctors Think reveals a profound new view of twenty-first-century medical practice, giving doctors and patients the vital information they need to make better judgments together.

The Cancer Chronicles: Unlocking Medicine's Deepest Mystery


George Johnson - 2013
    What he discovered is a revolution under way—an explosion of new ideas about what cancer really is and where it comes from. In a provocative and intellectually vibrant exploration, he takes us on an adventure through the history and recent advances of cancer research that will challenge everything you thought you knew about the disease. Deftly excavating and illuminating decades of investigation and analysis, he reveals what we know and don’t know about cancer, showing why a cure remains such a slippery concept. We follow him as he combs through the realms of epidemiology, clinical trials, laboratory experiments, and scientific hypotheses—rooted in every discipline from evolutionary biology to game theory and physics. Cogently extracting fact from a towering canon of myth and hype, he describes tumors that evolve like alien creatures inside the body, paleo-oncologists who uncover petrified tumors clinging to the skeletons of dinosaurs and ancient human ancestors, and the surprising reversals in science’s comprehension of the causes of cancer, with the foods we eat and environmental toxins playing a lesser role. Perhaps most fascinating of all is how cancer borrows natural processes involved in the healing of a wound or the unfolding of a human embryo and turns them, jujitsu-like, against the body. Throughout his pursuit, Johnson clarifies the human experience of cancer with elegiac grace, bearing witness to the punishing gauntlet of consultations, surgeries, targeted therapies, and other treatments. He finds compassion, solace, and community among a vast network of patients and professionals committed to the fight and wrestles to comprehend the cruel randomness cancer metes out in his own family. For anyone whose life has been affected by cancer and has found themselves asking why?, this book provides a new understanding. In good company with the works of Atul Gawande, Siddhartha Mukherjee, and Abraham Verghese, The Cancer Chronicles is endlessly surprising and as radiant in its prose as it is authoritative in its eye-opening science.

The Sick Rose: Disease and the Art of Medical Illustration


Richard Barnett - 2014
    The nineteenth century experienced an explosion of epidemics such as cholera and diphtheria, driven by industrialization, urbanization and poor hygiene. In this pre-color-photography era, accurate images were relied upon to teach students and aid diagnosis. The best examples, featured here, are remarkable pieces of art that attempted to elucidate the mysteries of the body, and the successive onset of each affliction. Bizarre and captivating images, including close-up details and revealing cross-sections, make all too clear the fascinations of both doctors and artists of the time. Barnett illuminates the fears and obsessions of a society gripped by disease, yet slowly coming to understand and combat it. The age also saw the acceptance of vaccination and the germ theory, and notable diagrams that transformed public health, such as John Snow's cholera map and Florence Nightingale's pioneering histograms, are included and explained. Organized by disease, "The Sick Rose" ranges from little-known ailments now all but forgotten to the epidemics that shaped the modern age. It is a fascinating "Wunderkammer" of a book that will enthrall artists, students, designers, scientists and the incurably curious everywhere.

The Lost Family: How DNA Testing Is Uncovering Secrets, Reuniting Relatives, and Upending Who We Are


Libby Copeland - 2020
    She explores the culture of genealogy buffs, the science of DNA, and the business of companies like Ancestry and 23andMe, all while tracing the story of one woman, her unusual results, and a relentless methodical drive for answers that becomes a thoroughly modern genetic detective story.

The View from Serendip


Arthur C. Clarke - 1977
    Memoirs of a British ex-patriot, who happened to be a celebrated novelist and social commentator.

The Language of Life: DNA and the Revolution in Personalized Medicine


Francis S. Collins - 2009
    Francis Collins, director of the National Institute of Health, 2007 recipient of the Presidential Medal of Freedom, and 15-year head of the Human Genome Project, comes one of the most important medical books of the year: The Language of Life. With accessible, insightful prose, Dr. Collins describes the medical, scientific, and genetic revolution that is currently unlocking the secrets of “personalized medicine,” and offers practical advice on how to utilize these discoveries for you and your family’s current and future health and well-being. In the words of Dr. Jerome Groopman (How Doctors Think), The Language of Life “sets out hope without hype, and will enrich the mind and uplift the heart.”