Professors are asked to consider their demise and to ruminate on what matters most to them: What wisdom would we impart to the world if we knew it was our last chance? If we had to vanish tomorrow, what would we want as our legacy?When Randy Pausch, a computer science professor at Carnegie Mellon, was asked to give such a lecture, he didn't have to imagine it as his last, since he had recently been diagnosed with terminal cancer. But the lecture he gave, 'Really Achieving Your Childhood Dreams', wasn't about dying. It was about the importance of overcoming obstacles, of enabling the dreams of others, of seizing every moment (because time is all you have and you may find one day that you have less than you think). It was a summation of everything Randy had come to believe. It was about living.In this book, Randy Pausch has combined the humour, inspiration, and intelligence that made his lecture such a phenomenon and given it an indelible form. It is a book that will be shared for generations to come.

    Bit by bit a mysterious illness stole away the pieces of his life: First, it took the strength of his legs, then his voice, and his ability to eat. Finally, even the sound of a footstep in his room became unbearable. The Puzzle Solver follows several years in which he desperately sought answers from specialist after specialist, where at one point his 6'3" frame dropped to 115 lbs. For years, he underwent endless medical tests, but doctors told him there was nothing wrong. Then, finally, a diagnosis: Chronic Fatigue Syndrome, also known as myalgic encephalomyelitis.In the 80s, when an outbreak of people immobilized by an indescribable fatigue were reported near Lake Tahoe, Nevada, doctors were at a loss to explain the symptoms. The condition would alternatively be nicknamed Raggedy Ann Syndrome or the Yuppie Disease, and there was no cure or answers about treatment. They were to remain sick.But there was one answer: Whitney's father, Ron Davis, PhD, a world-class geneticist at Stanford University whose legendary research helped crack the code of DNA, suddenly changed the course of his career in a race against time to cure his son's debilitating condition.In The Puzzle Solver, journalist Tracie White, who first wrote a viral and award-winning piece on Davis and his family in Stanford Medicine, tells his story. In gripping prose, she masterfully takes readers along on this journey with Davis to solve one of the greatest mysteries in medicine. In a piercing investigative narrative, closed doors are opened, and masked truths are exposed as Davis uncovers new proof confirming that Chronic Fatigue Syndrome is a biological disease.At the heart of this book is a moving story that goes far beyond medicine, this is a story about how the power of love -- and science -- can shine light in even the darkest, most hidden, corners of the world.

    Meredith May recalls the first time a honeybee crawled on her arm. She was five years old, her parents had recently split and suddenly she found herself in the care of her grandfather, an eccentric beekeeper who made honey in a rusty old military bus in the yard. That first close encounter was at once terrifying and exhilarating for May, and in that moment she discovered that everything she needed to know about life and family was right before her eyes, in the secret world of bees.May turned to her grandfather and the art of beekeeping as an escape from her troubled reality. Her mother had receded into a volatile cycle of neurosis and despair and spent most days locked away in the bedroom. It was during this pivotal time in May's childhood that she learned to take care of herself, forged an unbreakable bond with her grandfather and opened her eyes to the magic and wisdom of nature.The bees became a guiding force in May's life, teaching her about family and community, loyalty and survival and the unequivocal relationship between a mother and her child. Part memoir, part beekeeping odyssey, The Honey Bus is an unforgettable story about finding home in the most unusual of places, and how a tiny, little-understood insect could save a life.

    Her first book is a revelatory treatise on plant life—but it is also so much more. Lab Girl is a book about work, love, and the mountains that can be moved when those two things come together. It is told through Jahren’s stories: about her childhood in rural Minnesota with an uncompromising mother and a father who encouraged hours of play in his classroom’s labs; about how she found a sanctuary in science, and learned to perform lab work done “with both the heart and the hands”; and about the inevitable disappointments, but also the triumphs and exhilarating discoveries, of scientific work.Yet at the core of this book is the story of a relationship Jahren forged with a brilliant, wounded man named Bill, who becomes her lab partner and best friend. Their sometimes rogue adventures in science take them from the Midwest across the United States and back again, over the Atlantic to the ever-light skies of the North Pole and to tropical Hawaii, where she and her lab currently make their home.

    No money. No passport. No identity.Taken to a mental hospital by the police, MacLean then started to hallucinate so severely he had to be tied down. Soon he could remember song lyrics, but not his family, his friends, or the woman he was told he loved. All of these symptoms, it turned out, were the result of the commonly prescribed malarial medication he had been taking. Upon his return to the States, he struggled to piece together the fragments of his former life in a harrowing, absurd, and unforgettable journey back to himself.The Answer to the Riddle Is Me, drawn from David MacLean’s award-winning This American Life essay, is a deeply felt, closely researched, and intensely personal book. It asks every reader to confront the essential questions of our age: In our geographically and chemically fluid world, what makes me who I am? And how much can be stripped away before I become someone else entirely?

    When Sarah Perry was twelve, she saw a partial eclipse of the sun, an event she took as a sign of good fortune for her and her mother, Crystal. But that brief moment of darkness ultimately foreshadowed a much larger one: two days later, Crystal was murdered in their home in rural Maine, just a few feet from Sarah’s bedroom.   The killer escaped unseen; it would take the police twelve years to find him, time in which Sarah grew into adulthood, struggling with abandonment, police interrogations, and the effort of rebuilding her life when so much had been lost. Through it all she would dream of the eventual trial, a conviction—all her questions finally answered. But after the trial, Sarah’s questions only grew. She wanted to understand her mother’s life, not just her final hours, and so she began a personal investigation, one that drew her back to Maine, taking her deep into the abiding darkness of a small American town.   Told in searing prose, After the Eclipse is a luminous memoir of uncomfortable truth and terrible beauty, an exquisite memorial for a mother stolen from her daughter, and a blazingly successful attempt to cast light on her life once more.

    In this extraordinarily candid and radically inventive memoir, Machado tackles a dark and difficult subject with wit, inventiveness and an inquiring spirit, as she uses a series of narrative tropes—including classic horror themes—to create an entirely unique piece of work which is destined to become an instant classic.

    Nadine Burke Harris was already known as a crusading physician delivering targeted care to vulnerable children. But it was Diego — a boy who had stopped growing after a sexual assault — who galvanized her journey to uncover the connections between toxic stress and lifelong illnesses.The news of Burke Harris’s research is just how deeply our bodies can be imprinted by ACEs—adverse childhood experiences like abuse, neglect, parental addiction, mental illness, and divorce. Childhood adversity changes our biological systems, and lasts a lifetime.  For anyone who has faced a difficult childhood, or who cares about the millions of children who do, the scientific insight and innovative, acclaimed health interventions in The Deepest Well represent hope for preventing lifelong illness for those we love and for generations to come​.

     From the moment she uttered the brave and honest words, "I am an alcoholic," to interviewer George Stephanopoulos, Elizabeth Vargas began writing her story, as her experiences were still raw. Now, in Between Breaths, Vargas discusses her accounts of growing up with anxiety--which began suddenly at the age of six when her father served in Vietnam--and how she dealt with this anxiety as she came of age, eventually turning to alcohol for a release from her painful reality. The now-A&E Network reporter reveals how she found herself living in denial about the extent of her addiction, and how she kept her dependency a secret for so long. She addresses her time in rehab, her first year of sobriety, and the guilt she felt as a working mother who could never find the right balance between a career and parenting. Honest and hopeful, Between Breaths is an inspiring read. Winner of the Books for a Better Life Award in the First Book category Instant New York Times and USA Today Bestseller

    You might even be worried that these lapses in memory could be an early sign of Alzheimer's or dementia. In reality, for the vast majority of us, these examples of forgetting are completely normal. Why? Because while memory is amazing, it is far from perfect. Our brains aren't designed to remember every name we hear, plan we make, or day we experience. Just because your memory sometimes fails doesn't mean it's broken or succumbing to disease. Forgetting is actually part of being human. In Remember, neuroscientist and acclaimed novelist Lisa Genova delves into how memories are made and how we retrieve them. You'll learn whether forgotten memories are temporarily inaccessible or erased forever and why some memories are built to exist for only a few seconds (like a passcode) while others can last a lifetime (your wedding day). You'll come to appreciate the clear distinction between normal forgetting (where you parked your car) and forgetting due to Alzheimer's (that you own a car). And you'll see how memory is profoundly impacted by meaning, emotion, sleep, stress, and context. Once you understand the language of memory and how it functions, its incredible strengths and maddening weaknesses, its natural vulnerabilities and potential superpowers, you can both vastly improve your ability to remember and feel less rattled when you inevitably forget. You can set educated expectations for your memory, and in doing so, create a better relationship with it. You don't have to fear it anymore. And that can be life-changing.

    These pieces are not a metaphor. They are actual pieces. Twenty years after the publication of her iconic Shutterbabe, we remeet Deborah Copaken at her darkly comedic nadir: battered, broke, divorcing, dissected, and dying—literally—on sexism’s battlefield as she deliriously scoops up what she believes to be her internal organs, which have fallen out of her body, into a glass Tupperware container before heading off to the hospital for emergency surgery . . . in an UberPool.Part cri de coeur cautionary tale, part dystopian tragicomedy, Ladyparts is Copaken’s irreverent inventory of both the female body and the body politic of womanhood in America. With her journalist’s eye, her novelist’s heart, and her performer’s sense of timing, she provides a frontline account of one woman brought to her knees by the one-two-twelve punch of divorce, solo motherhood, lack of healthcare, unaffordable childcare, shady landlords, her father’s death, college tuitions, sexual harassment, corporate indifference, ageism, sexism, and just plain old bad luck. Plus seven serious illnesses, one on top of the other, which provide the book’s narrative skeleton: vagina, uterus, breast, heart, cervix, brain, and lungs. She keeps bouncing back from each bum body part and finding the black humor in every setback, but in her slippery struggle to survive a steep plunge off the middle-class ladder, she is suddenly awoken to what it means to have no safety net.Turning her Harlem home into a commune to pay rent and have childcare, she trades her life as a bestselling novelist to apply for full-time corporate gigs that come with health insurance but often not scruples. She gets fired from a health magazine for being unhealthy; laid off from a PR firm for rushing home to deal with a child’s medical emergency; and sexually harassed out of her newspaper column, only to be grilled by the FBI when her harasser is offered a plum job in the White House.Side-splittingly funny one minute, a freak horror show the next, and quintessentially American, Ladyparts is an era-defining memoir for our time.

     Her pioneering research on how the chemicals inside our bodies form a dynamic information network, linking mind and body, is not only provocative, it is revolutionary. By establishing the biomolecular basis for our emotions and explaining these new scientific developments in a clear and accessible way, Pert empowers us to understand ourselves, our feelings, and the connection between our minds and our bodies -- body-minds -- in ways we could never possibly have imagined before. Molecules of Emotion is a landmark work, full of insight and wisdom and possessing that rare power to change the way we see the world and ourselves.

    Why cope with insecurities I don't already have?That last one's just me? All right, then.But if the rest sounds familiar, you are experiencing Girl Logic: a characteristically female way of thinking that appears contradictory and circuitous but is actually a complicated and highly evolved way of looking at the world. You end up considering every repercussion of every choice (about dating, career, clothes, lunch) before making a move toward what you really want. And why do we attempt these mental hurdles? Well, that's what this book is all about.The fact is, whether you're obsessing over his last text or the most important meeting of your career, your Girl Logic serves a purpose: It helps push you, question what you want, and clarify what will make you a happier, better person. Girl Logic can be every confident woman's secret weapon, and this book shows you how to wield it.

    But never had he faced the need to counsel himself until his wife, esteemed feminist author Marilyn Yalom, was diagnosed with cancer. In A Matter of Death and Life, Marilyn and Irv share how they took on profound new struggles: Marilyn to die a good death, Irv to live on without her.In alternating accounts of their last months together and Irv's first months alone, they offer us a rare window into facing mortality and coping with the loss of one's beloved. The Yaloms had numerous blessings--a loving family, a Palo Alto home under a magnificent valley oak, a large circle of friends, avid readers around the world, and a long, fulfilling marriage--but they faced death as we all do. With the wisdom of those who have thought deeply, and the familiar warmth of teenage sweethearts who've grown up together, they investigate universal questions of intimacy, love, and grief.Informed by two lifetimes of experience, A Matter of Death and Life is an openhearted offering to anyone seeking support, solace, and a meaningful life.

    In Lost & Found, she weaves the story of those relationships into a brilliant exploration of the role that loss and discovery play in all of our lives. The resulting book is part memoir, part guidebook to living in a world that is simultaneously full of wonder and joy and wretchedness and suffering--a world that always demands both our gratitude and our grief. A staff writer at The New Yorker and winner of the Pulitzer Prize, Schulz writes with curiosity, tenderness, erudition, and wit about our finite yet infinitely complicated lives. Lost & Found is an enduring account of love in all its many forms from one of the great writers of our time.