His contribution to our understanding not only of mental illness but also of the human condition is truly stunning.The Noonday Demon examines depression in personal, cultural, and scientific terms. Drawing on his own struggles with the illness and interviews with fellow sufferers, doctors and scientists, policymakers and politicians, drug designers and philosophers, Solomon reveals the subtle complexities and sheer agony of the disease. He confronts the challenge of defining the illness and describes the vast range of available medications, the efficacy of alternative treatments, and the impact the malady has had on various demographic populations around the world and throughout history. He also explores the thorny patch of moral and ethical questions posed by emerging biological explanations for mental illness.The depth of human experience Solomon chronicles, the range of his intelligence, and his boundless curiosity and compassion will change the reader's view of the world.

    It is a poignant observation about the relationship between Mira, her sister, and their mentally ill mother. Before she was struck with schizophrenia at the age of nineteen, beautiful piano protégé Norma Herr had been the most vibrant personality in the room. She loved her daughters and did her best to raise them well, but as her mental state deteriorated, Norma spoke less about Chopin and more about Nazis and her fear that her daughters would be kidnapped, murdered, or raped. When the girls left for college, the harassment escalated--Norma called them obsessively, appeared at their apartments or jobs, threatened to kill herself if they did not return home. After a traumatic encounter, Mira and her sister were left with no choice but to change their names and sever all contact with Norma in order to stay safe. But while Mira pursued her career as an artist--exploring the ancient romance of Florence, the eerie mysticism of northern Norway, and the raw desert of Israel--the haunting memories of her mother were never far away. Then one day, Mira’s life changed forever after a debilitating car accident. As she struggled to recover from a traumatic brain injury, she was confronted with a need to recontextualize her life--she had to relearn how to paint, read, and interact with the outside world. In her search for a way back to her lost self, Mira reached out to the homeless shelter where she believed her mother was living and discovered that Norma was dying. Mira and her sister traveled to Cleveland, where they shared an extraordinary reconciliation with their mother that none of them had thought possible. At the hospital, Mira discovered a set of keys that opened a storage unit Norma had been keeping for seventeen years. Filled with family photos, childhood toys, and ephemera from Norma’s life, the storage unit brought back a flood of previous memories that Mira had thought were lost to her forever. The Memory Palace is a breathtaking literary memoir about the complex meaning of love, truth, and the capacity for forgiveness among family. Through stunning prose and original art created by the author in tandem with the text, The Memory Palace explores the connections between mother and daughter that cannot be broken no matter how much exists--or is lost--between them.

    It was no wonder he gravitated to machines, which could, at least, be counted on.After fleeing his parents and dropping out of high school, his savant-like ability to visualize electronic circuits landed him a gig with KISS, for whom he created their legendary fire-breathing guitars. Later, he drifted into a “real” job, as an engineer for a major toy company. But the higher Robison rose in the company, the more he had to pretend to be “normal” and do what he simply couldn’t: communicate. It wasn’t worth the paycheck.It was not until he was forty that an insightful therapist told him he had the form of autism called Asperger’s syndrome. That understanding transformed the way Robison saw himself—and the world.Look Me in the Eye is the moving, darkly funny story of growing up with Asperger’s at a time when the diagnosis simply didn’t exist. A born storyteller, Robison takes you inside the head of a boy whom teachers and other adults regarded as “defective,” who could not avail himself of KISS’s endless supply of groupies, and who still has a peculiar aversion to using people’s given names (he calls his wife “Unit Two”). He also provides a fascinating reverse angle on the younger brother he left at the mercy of their nutty parents—the boy who would later change his name to Augusten Burroughs and write the bestselling memoir Running with Scissors.Ultimately, this is the story of Robison’s journey from his world into ours, and his new life as a husband, father, and successful small business owner—repairing his beloved high-end automobiles. It’s a strange, sly, indelible account—sometimes alien, yet always deeply human.

    Days earlier, she had been on the threshold of a new, adult life: at the beginning of her first serious relationship and a promising career at a major New York newspaper. Now she was labeled violent, psychotic, a flight risk. What happened?In a swift and breathtaking narrative, Cahalan tells the astonishing true story of her descent into madness, her family’s inspiring faith in her, and the lifesaving diagnosis that nearly didn’t happen.

    Just twelve, she’s tall, skinny, and weak. It’s four o’clock, and she hasn’t been allowed to eat anything all day. Her mother, on the other hand, seems curiously excited. She's about to suggest open-heart surgery on her child to "get to the bottom of this." She checks her teeth for lipstick and, as the doctor enters, shoots the girl a warning glance. This child will not ruin her plans.SickenedFrom early childhood, Julie Gregory was continually X-rayed, medicated, and operated on—in the vain pursuit of an illness that was created in her mother’s mind. Munchausen by proxy (MBP) is the world’s most hidden and dangerous form of child abuse, in which the caretaker—almost always the mother—invents or induces symptoms in her child because she craves the attention of medical professionals. Many MBP children die, but Julie Gregory not only survived, she escaped the powerful orbit of her mother's madness and rebuilt her identity as a vibrant, healthy young woman.Sickened is a remarkable memoir that speaks in an original and distinctive Midwestern voice, rising to indelible scenes in prose of scathing beauty and fierce humor. Punctuated with Julie's actual medical records, it re-creates the bizarre cocoon of her family's isolated double-wide trailer, their wild shopping sprees and gun-waving confrontations, the astonishing naïveté of medical professionals and social workers. It also exposes the twisted bonds of terror and love that roped Julie's family together—including the love that made a child willing to sacrifice herself to win her mother's happiness. The realization that the sickness lay in her mother, not in herself, would not come to Julie until adulthood. But when it did, it would strike like lightning. Through her painful metamorphosis, she discovered the courage to save her own life—and, ultimately, the life of the girl her mother had found to replace her. Sickened takes us to new places in the human heart and spirit. It is an unforgettable story, unforgettably told.

    She was a poor Southern tobacco farmer who worked the same land as her enslaved ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine. The first “immortal” human cells grown in culture, they are still alive today, though she has been dead for more than sixty years. If you could pile all HeLa cells ever grown onto a scale, they’d weigh more than 50 million metric tons—as much as a hundred Empire State Buildings. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions.Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave.Now Rebecca Skloot takes us on an extraordinary journey, from the “colored” ward of Johns Hopkins Hospital in the 1950s to stark white laboratories with freezers full of HeLa cells; from Henrietta’s small, dying hometown of Clover, Virginia — a land of wooden quarters for enslaved people, faith healings, and voodoo — to East Baltimore today, where her children and grandchildren live and struggle with the legacy of her cells.Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family — past and present — is inextricably connected to the history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of.Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah, who was devastated to learn about her mother’s cells. She was consumed with questions: Had scientists cloned her mother? Did it hurt her when researchers infected her cells with viruses and shot them into space? What happened to her sister, Elsie, who died in a mental institution at the age of fifteen? And if her mother was so important to medicine, why couldn’t her children afford health insurance?Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.

    Styron is perhaps the first writer to convey the full terror of depression's psychic landscape, as well as the illuminating path to recovery.

    She recounts the travails of growing up in a large, affluent family where there was a paucity of love and of basics such as food and clothing despite the presence of a chauffeur and a cook. She goes on to recount her early hospitalization for depression in poignant detail, as well as her complex relationship with her mercurial, withholding mother.Along the way Merkin also discusses her early, redemptive love of reading and gradual emergence as a writer. She eventually marries, has a child, and suffers severe postpartum depression, for which she is again hospitalized. Merkin also discusses her visits to various therapists and psychopharmocologists, which enables her to probe the causes of depression and its various treatments. The book ends in the present, where the writer has learned how to navigate her depression, if not “cure” it, after a third hospitalization in the wake of her mother’s death.

    This was a girl who succeeded at everything she tried, and who was only getting started.But when Maddy began her long-awaited college career, her parents noticed something changed. Previously indefatigable Maddy became withdrawn, and her thoughts centered on how she could change her life. In spite of thousands of hours of practice and study, she contemplated transferring from the school that had once been her dream. When Maddy's dad, Jim, dropped her off for the first day of spring semester, she held him a second longer than usual. That would be the last time Jim would see his daughter.What Made Maddy Run began as a piece that Kate Fagan, a columnist for espnW, wrote about Maddy's life. What started as a profile of a successful young athlete whose life ended in suicide became so much larger when Fagan started to hear from other college athletes also struggling with mental illness. This is the story of Maddy Holleran's life, and her struggle with depression, which also reveals the mounting pressures young people, and college athletes in particular, face to be perfect, especially in an age of relentless connectivity and social media saturation.

    No money. No passport. No identity.Taken to a mental hospital by the police, MacLean then started to hallucinate so severely he had to be tied down. Soon he could remember song lyrics, but not his family, his friends, or the woman he was told he loved. All of these symptoms, it turned out, were the result of the commonly prescribed malarial medication he had been taking. Upon his return to the States, he struggled to piece together the fragments of his former life in a harrowing, absurd, and unforgettable journey back to himself.The Answer to the Riddle Is Me, drawn from David MacLean’s award-winning This American Life essay, is a deeply felt, closely researched, and intensely personal book. It asks every reader to confront the essential questions of our age: In our geographically and chemically fluid world, what makes me who I am? And how much can be stripped away before I become someone else entirely?

    She also lectures widely on autism—because Temple Grandin is autistic, a woman who thinks, feels, and experiences the world in ways that are incomprehensible to the rest of us. In this unprecedented book, Grandin delivers a report from the country of autism. Writing from the dual perspectives of a scientist and an autistic person, she tells us how that country is experienced by its inhabitants and how she managed to breach its boundaries to function in the outside world. What emerges in Thinking in Pictures is the document of an extraordinary human being, one who, in gracefully and lucidly bridging the gulf between her condition and our own, sheds light on the riddle of our common identity.

     It is a remarkable portrait, too, of the life of a psychiatric asylum--the sort of community in which, for better and for worse, hundreds of thousands of people lived out their lives.More than four hundred abandoned suitcases filled with patients’ belongings were found when Willard Psychiatric Center closed in 1995 after 125 years of operation. They are skillfully examined here and compared to the written record to create a moving—and devastating—group portrait of twentieth-century American psychiatric care.

    David Kushner grew up in the suburbs of Florida in the early 1970s, running wild with his friends, exploring, riding bikes, and disappearing into the nearby woods for hours at a time. One morning in 1973, however, everything changed. David's older brother Jon, making a trip to the local convenience store, vanished. This is the story of Jon's murder at the hands of two sadistic drifters and everything that happened after. "Alligator Candy "isn't only the chronicle of Jon's death, it is also the story of how parenting in America changed, casting light on the transition between two generations of children one raised on freedom, the other on fear. Jon's death was one of the first in what turned out to be a rash of child abductions and murders that dominated headlines for much of the 1970s and 80s. It was around this time that milk cartons began to feature the images of missing children, and newscasters began asking, It's 10:00, do you know where you children are? When one of Jon's killers received a parole hearing, David revisited the case that had so haunted him. Marshalling his skills as a journalist, he compiled all the details that he was sheltered from as a child, interviewing neighbors, reporters, cops, and his own family, and combing through yellowed news clippings. Haunting and intimate, "Alligator Candy" is a moving, disturbing, insightful, and inspiring meditation on grief, growth, family, and survival."

    Odder still, she reveals that she’s suffering from a persistent memory problem. Routinely, she “loses” parts of her day, finding herself in places she doesn’t remember going to or being told about conversations she doesn’t remember having. Her problems are so pervasive that she often feels like an impersonator in her own life; she doesn’t recognize the people who call themselves her friends, and she can’t even remember being intimate with her own husband. Baer recognizes that Karen is on the verge of suicide and, while trying various medications to keep her alive, attempts to discover the root cause of her strange complaints. It’s the work of months, and then years, to gain Karen’s trust and learn the true extent of the trauma buried in her past. What she eventually reveals is nearly beyond belief, a narrative of a childhood spent grappling with unimaginable horror. How has Karen survived with even a tenuous grasp on sanity?Then Baer receives an envelope in the mail. It’s marked with Karen’s return address but contains a letter from a little girl who writes that she’s seven years old and lives inside of Karen. Soon Baer receives letters from others claiming to be parts of Karen. Under hypnosis, these alternate Karen personalities reveal themselves in shocking variety and with undeniable traits—both physical and psychological. One “alter” is a young boy filled with frightening aggression; another an adult male who considers himself Karen’s protector; and a third a sassy flirt who seeks dominance over the others. It’s only by compartmentalizing her pain, guilt, and fear in this fashion—by “switching time” with alternate selves as the situation warrants—that Karen has been able to function since childhood.Realizing that his patient represents an extreme case of multiple personality disorder, Baer faces the daunting task of creating a therapy that will make Karen whole again. Somehow, in fact, he must gain the trust of each of Karen’s seventeen “alters” and convince them of the necessity of their own annihilation.As powerful as Sybil or The Three Faces of Eve, Switching Time is the first complete account of such therapy to be told from the perspective of the treating physician, a stunningly devoted healer who worked selflessly for decades so that Karen could one day live as a single human being.From the Hardcover edition.

    I bump along, in fits and starts, on a perpetual path to finding better ways for me and my mate, Anxiety, to get around. It's everything I do.Sarah Wilson—bestselling author and entrepreneur, intrepid solver of problems and investigator of how to live a better life—has helped over 1.2 million people across the world to quit sugar. She has also been an anxiety sufferer her whole life.In her new book, she directs her intense focus and fierce investigatory skills onto this lifetime companion of hers, looking at the triggers and treatments, the fashions and fads. She reads widely and interviews fellow sufferers, mental health experts, philosophers, and even the Dalai Lama, processing all she learns through the prism her own experiences.Sarah pulls at the thread of accepted definitions of anxiety, and unravels the notion that it is a difficult, dangerous disease that must be medicated into submission. Ultimately, she re-frames anxiety as a spiritual quest rather than a burdensome affliction, a state of yearning that will lead us closer to what really matters.Practical and poetic, wise and funny, this is a small book with a big heart. It will encourage the myriad sufferers of the world's most common mental illness to feel not just better about their condition, but delighted by the possibilities it offers for a richer, fuller life.