For every one of the cells that make up the vessel that you call your body, there are nine impostor cells hitching a ride. You are not just flesh and blood, muscle and bone, brain and skin, but also bacteria and fungi. Over your lifetime, you will carry the equivalent weight of five African elephants in microbes. You are not an individual but a colony.Until recently, we had thought our microbes hardly mattered, but science is revealing a different story, one in which microbes run our bodies and becoming a healthy human is impossible without them.In this riveting, shocking, and beautifully written book, biologist Alanna Collen draws on the latest scientific research to show how our personal colony of microbes influences our weight, our immune system, our mental health, and even our choice of partner. She argues that so many of our modern diseases—obesity, autism, mental illness, digestive disorders, allergies, autoimmunity afflictions, and even cancer—have their root in our failure to cherish our most fundamental and enduring relationship: that with our personal colony of microbes.Many of the questions about modern diseases left unanswered by the Human Genome Project are illuminated by this new science. And the good news is that unlike our human cells, we can change our microbes for the better. Collen's book is a revelatory and indispensable guide. It is science writing at its most relevant: life—and your body—will never seem the same again.

    When a small vial arrives in her mailbox from "Lewis Carroll," Ayelet Waldman is at a low point. Her mood storms have become intolerably severe; she has tried nearly every medication possible; her husband and children are suffering with her. So she opens the vial, places two drops on her tongue, and joins the ranks of an underground but increasingly vocal group of scientists and civilians successfully using therapeutic microdoses of LSD. As Waldman charts her experience over the course of a month--bursts of productivity, sleepless nights, a newfound sense of equanimity--she also explores the history and mythology of LSD, the cutting-edge research into the drug, and the byzantine policies that control it. Drawing on her experience as a federal public defender, and as the mother of teenagers, and her research into the therapeutic value of psychedelics, Waldman has produced a book that is eye-opening, often hilarious, and utterly enthralling.

    Nuland profoundly altered our perception of the end of life. Now in The Art of Aging, Dr. Nuland steps back to explore the impact of aging on our minds and bodies, strivings and relationships. Melding a scientist’s passion for truth with a humanist’s understanding of the heart and soul, Nuland has created a wise, frank, and inspiring book about the ultimate stage of life’s journey.The onset of aging can be so gradual that we are often surprised to find that one day it is fully upon us. The changes to the senses, appearance, reflexes, physical endurance, and sexual appetites are undeniable–and rarely welcome–and yet, as Nuland shows, getting older has its surprising blessings. Age concentrates not only the mind, but the body’s energies, leading many to new sources of creativity, perception, and spiritual intensity. Growing old, Nuland teaches us, is not a disease but an art–and for those who practice it well, it can bring extraordinary rewards.“I’m taking the journey even while I describe it,” writes Nuland, now in his mid-seventies and a veteran of nearly four decades of medical practice. Drawing on his own life and work, as well as the lives of friends both famous and not, Nuland portrays the astonishing variability of the aging experience. Faith and inner strength, the deepening of personal relationships, the realization that career does not define identity, the acceptance that some goals will remain unaccomplished–these are among the secrets of those who age well.Will scientists one day fulfill the dream of eternal youth? Nuland examines the latest research into extending life and the scientists who are pursuing it. But ultimately, what compels him most is what happens to the mind and spirit as life reaches its culminating decades. Reflecting the wisdom of a long lifetime, The Art of Aging is a work of luminous insight, unflinching candor, and profound compassion.From the Hardcover edition.

    

    They always keep a bag packed. They seldom have more than twenty-four hours' notice before they are dispatched. The phone calls that tell them to head to the airport, sometimes in the middle of the night, may give them no more information than the country they are traveling to and the epidemic they will tackle when they get there.The universal human instinct is to run from an outbreak of disease. These doctors run toward it.They are the disease detective corps of the U.S. Centers for Disease Control and Prevention (CDC), the federal agency that tracks and tries to prevent disease outbreaks and bioterrorist attacks around the world. They are formally called the Epidemic Intelligence Service (EIS) -- a group founded more than fifty years ago out of fear that the Korean War might bring the use of biological weapons -- and, like intelligence operatives in the traditional sense, they perform their work largely in anonymity. They are not household names, but over the years they were first to confront the outbreaks that became known as hantavirus, Ebola virus, and AIDS. Now they hunt down the deadly threats that dominate our headlines: West Nile virus, anthrax, and SARS.In this riveting narrative, Maryn McKenna -- the only journalist ever given full access to the EIS in its fifty-three-year history -- follows the first class of disease detectives to come to the CDC after September 11, the first to confront not just naturally occurring outbreaks but the man-made threat of bioterrorism. They are talented researchers -- many with young families -- who trade two years of low pay and extremely long hours for the chance to be part of the group that has helped eradicate smallpox, push back polio, and solve the first major outbreaks of Legionnaires' disease, toxic shock syndrome, and "E. coli" O157.Urgent, exhilarating, and compelling, "Beating Back the Devil" goes with the EIS as they try to stop epidemics -- before the epidemics stop us.

    He was doing a public access show up north when MTV heard about him and brought him to New York to see what he could do in the big city. Tom became an instant smash, slicing up dead raccoons on stage, introducing his parents to Monica Lewinsky in the middle of the night, and pioneering a type of shocking humor that begat Jackass, Fear Factor, and other reality shows.In the next few years, Tom starred in the hilarious Road Trip and three other movies (Freddy Got Fingered, Stealing Harvard, and Charlie’s Angels), married and divorced Drew Barrymore, and recorded his surgery for testicular cancer in a well-received, hysterical, and oddly moving documentary for MTV. But the fearless Canadian with the outrageous sense of humor, hit show, and tabloid-hyped marriage got a taste of the darker side of Hollywood, too, as the media that made him the toast of Tinseltown cut him down to size in the wake of his divorce, illness, and some professional bumps in the road.Hollywood Causes Cancer not only tells the full story of Tom’s wildly entertaining trip to celebrity but is also an absorbing and even revelatory look at a dramatic, excessive, ruthless place called Hollywood, and how one man survived his journey into the heart of it all.

    But the fanfare soon turned into a nightmare. During chemotherapy treatments, 857 patients who were already waging the fights of their lives against cancer were inexplicably exposed to the deadly, blood-borne hepatitis C virus. At least ninety-nine of them contracted the lethal illness. The horror was unprecedented as this was the largest healthcare-transmitted outbreak of hepatitis C in American history, and remains so to this date. A Never Event - a term used to describe a preventable medical tragedy - is a searing account of the health challenges these patients encountered and their quest for justice, as well as the painstaking investigation to uncover the source of the outbreak. It s a story of recklessness, deception and betrayal by the person these patients should have been able to trust the most: their physician, a man who, when the outbreak was discovered, fled the US for his native country in the Middle East. Written by a survivor of the tragedy and an attorney who represented many of the victims, A Never Event is a wake-up call to medical and legal communities nationwide.

    For two years her mind was dark, but in the third year, her mind broke free, and she was able to think clearly and to hear and feel everything—but no one knew. When she was fifteen years old, against all odds and medical predictions, she was finally able to communicate through eye blinks, and she gradually regained her ability to speak and eat and move her upper body, but she faced the devastating reality of paralysis from the waist down because of damage to her spine. However, Victoria didn’t lose her strength or steadfast determination, and two years later, she won a gold medal for swimming at the London 2012 Paralympics. In Locked In, Victoria shares her never-before-published story—the pain, the struggle, the fight to live and thrive, and most importantly, the faith that carried her through. Her journey was not easy, but by believing in God’s healing power and forgiveness, she is living proof that, despite seemingly insurmountable odds and challenges, the will to survive and resolve to live can be a force stronger than our worst deterrents. Not many people get a second chance at life like Victoria has, and she made a promise to God that she would make every moment count.

    Brought up in Washington, DC, in an abusive family, she went to Harvard, where she met her husband. They stayed together through medical school until two months before she was scheduled to join the staff of a hospital in central Philadelphia, when he told her he couldn't move with her. Her marriage at an end, Harper began her new life in a new city, in a new job, as a newly single woman.In the ensuing years, as Harper learned to become an effective ER physician, bringing insight and empathy to every patient encounter, she came to understand that each of us is broken—physically, emotionally, psychically. How we recognize those breaks, how we try to mend them, and where we go from there are all crucial parts of the healing process.The Beauty in Breaking is the poignant true story of Harper's journey toward self-healing. Each of the patients Harper writes about taught her something important about recuperation and recovery. How to let go of fear even when the future is murky. How to tell the truth when it's simpler to overlook it. How to understand that compassion isn't the same as justice. As she shines a light on the systemic disenfranchisement of the patients she treats as they struggle to maintain their health and dignity, Harper comes to understand the importance of allowing ourselves to make peace with the past as we draw support from the present. In this hopeful, moving, and beautiful book, she passes along the precious, necessary lessons that she has learned as a daughter, a woman, and a physician.

    Left untouched were many of the things known to cause cancer, including tobacco, the workplace, radiation, or the global environment. Proof of how the world in which we live and work affects whether we get cancer was either overlooked or suppressed. This has been no accident. The War on Cancer was run by leaders of industries that made cancer-causing products, and sometimes also profited from drugs and technologies for finding and treating the disease. Filled with compelling personalities and never-before-revealed information, The Secret History of the War on Cancer shows how we began fighting the wrong war, with the wrong weapons, against the wrong enemies-a legacy that persists to this day. This is the gripping story of a major public health effort diverted and distorted for private gain. A portion of the profits from this book will go to support research on cancer prevention.

    But behind the successful, glamorous career was a story that many of her friends and colleagues knew nothing about—her ongoing struggle with severe depression and alcoholism. Brampton's is a candid, tremendously honest telling of how she was finally able to "address the elephant in the room," and of a culture that sends the overriding message that people who suffer from depression are somehow responsible for their own illness. She offers readers a unique perspective of depression from the inside that is at times wrenching, but ultimately inspirational, as it charts her own coming back to life. Beyond her personal story, Brampton offers practical advice to all those affected by this illness. This book will resonate with any person whose life has been haunted by depression, at the same time offering help and understanding to those whose loved ones suffer from this debilitating condition.

    Having covered the war in Iraq and moved to Mexico City with two babies in nappies, he and his wife Diana thought they understood something about the subject.But when they arrived in Sydney so that Cave could establish The New York Times's Australia Bureau, life near the ocean confronted them with new ideas and questions, at odds with their American mindset that risk was a matter of individual choices. Surf-lifesaving and Nippers showed that perhaps it could be managed together, by communities. And instead of being either eliminated or romanticised, it might instead be respected and even embraced.And so Cave set out to understand how our current attitude to risk developed - and why it's not necessarily good for us.Into the Rip is partly the story of this New York family learning to live better by living with the sea and it is partly the story of how humans manage the idea of risk. Interviewing experts and everyday heroes, Cave asks critical questions like: Is safety overrated? Why do we miscalculate risk so often and how can we improve? Is it selfish to take risks or can more exposure make for stronger families, citizens and nations? And how do we factor in legitimate fears and major disasters like Cave has covered in his time here: the Black Summer fires; the Christchurch massacre; and, of course, Covid?The result is Grit meets Phosphorescence and Any Ordinary Day - a book that will change the way you and your family think about facing the world's hazards.

    She was 52.Paralysed from the top of her chest down, she was to spend almost a full year in hospital, determinedly working towards gaining as much movement in her limbs as possible, and learning to navigate her way through a world that had previously been invisible to her.As a journalist Melanie had always turned to words and now, on a spinal ward peopled by an extraordinary array of individuals who were similarly at sea, she decided that writing would be her life-line. The World I Fell Out Of is an account of that year, and of those that followed. It is the untold ‘back story’ behind Melanie’s award-winning ‘Spinal Column’ in The Times Magazine and a testament to ‘the art of getting on with it’.Unflinchingly honest and beautifully observed, this is a memoir about the joy – and the risks – of riding horses, the complicated nature of heroism, the bonds of family and the comfort of strangers. Above all, The World I Fell Out Of is a reminder that at any moment the life we know can be turned upside down – and a plea to start appreciating what we have while we have it.

    The childhood illness that left her bedridden for a year, which she was not expected to survive. A teenage yearning to escape that nearly ended in disaster. An encounter with a disturbed man on a remote path. And, most terrifying of all, an ongoing, daily struggle to protect her daughter--for whom this book was written--from a condition that leaves her unimaginably vulnerable to life's myriad dangers.Seventeen discrete encounters with Maggie at different ages, in different locations, reveal a whole life in a series of tense, visceral snapshots. In taut prose that vibrates with electricity and restrained emotion, O'Farrell captures the perils running just beneath the surface, and illuminates the preciousness, beauty, and mysteries of life itself.

    A reckoning, when the things you have been pushing to the background, come forward and demand your attention.Written by Daniel Howell, in conjunction with a qualified psychologist, in an entertaining and personal way from the perspective of someone who has been through it all—this no-nonsense book gives you the tools to understand your mind so you can be in control and really live. Split into three chapters for each stage of the journey:This Night - how to get through your toughest moments and be prepared to face anything. Tomorrow - small steps to change your thoughts and actions with a big impact on your life. The Days After - help to look after yourself in the long term and not just survive, but thrive.You will laugh and learn—but most of all, this book will assure you that even in your darkest times, there is always hope. You will get through this night.