They are the powerhouses of our cells, essential for the production and management of energy at cell level. Dr Sarah Myhill, together with Dr John McLaren Howard of Acumen Laboratories and Dr Norman Booth of Mansfield College Oxford, has spent many years studying the relationship between their malfunction and the commonest problem seen by GPs in the UK – fatigue. Their research findings have been published in three scientific papers in the International Journal of Clinical and Experimental Medicine, in 2009, 2012 and 2013. These studies showed that poor functioning of the mitochondria is the central problem in CFS. Patients with the worst mitochondrial function had the worst fatigue and vice versa. This is solid scientific evidence that CFS is a problem with mitochondria and has allowed the objective measurement of fatigue for the first time. With the publication of the third study, which showed that mitochondrial function tests and symptoms improved in patients who took measures to address their mitochondrial problems, Dr Myhill was ready to write this book. Here she explains the importance of healthy mitochondria, how we can measure their functioning and what we can do to keep them healthy, or restore them to health if problems arise. CFS is all in our cells, not in our minds!

    But most of us know very little about how the disease works, why we treat it the way we do, and the personalities whose dedication got us where we are today. For fifty years, Dr. Vincent T. DeVita Jr. has been one of those key players: he has held just about every major position in the field, and he developed the first successful chemotherapy treatment for Hodgkin’s lymphoma, a breakthrough the American Society of Clinical Oncologists has called the top research advance in half a century of chemotherapy. As one of oncology’s leading figures, DeVita knows what cancer looks like from the lab bench and the bedside. The Death of Cancer is his illuminating and deeply personal look at the science and the history of one of the world’s most formidable diseases. In DeVita’s hands, even the most complex medical concepts are comprehensible.Cowritten with DeVita’s daughter, the science writer Elizabeth DeVita-Raeburn, The Death of Cancer is also a personal tale about the false starts and major breakthroughs, the strong-willed oncologists who clashed with conservative administrators (and one another), and the courageous patients whose willingness to test cutting-edge research helped those oncologists find potential treatments. An emotionally compelling and informative read, The Death of Cancer is also a call to arms. DeVita believes that we’re well on our way to curing cancer but that there are things we need to change in order to get there. Mortality rates are declining, but America’s cancer patients are still being shortchanged—by timid doctors, by misguided national agendas, by compromised bureaucracies, and by a lack of access to information about the strengths and weaknesses of the nation’s cancer centers.With historical depth and authenticity, DeVita reveals the true story of the fight against cancer. The Death of Cancer is an ambitious, vital book about a life-and-death subject that touches us all.

    The ultimate reference to 355 dinosaurs from the Triassic, Jurassic and Cretaceous periods, including more than 900 watercolors, maps, timelines and photographs.Includes the best-known non-dinosaurs such as sea-living placodonts, nothosaurs, plesiosaurs, mosasaurs and ichthyosaurs, as well as the airborne pterosaurs.With informative descriptions, technically accurate profiles, anatomical illustrations, depictions of dinosaur habitats, and maps of fossil sites.

    We have all benefited from the medical discoveries of primate research--vaccines for polio, rubella, and hepatitis B are just a few. But we have also learned more in recent years about how intelligent apes and monkeys really are: they can speak to us with sign language, they can even play video games (and are as obsessed with the games as any human teenager). And activists have also uncovered widespread and unnecessarily callous treatment of animals by researchers (in 1982, a Silver Spring lab was charged with 17 counts of animal cruelty). It is a complex issue, made more difficult by the combative stance of both researchers and animal activists. In The Monkey Wars, Deborah Blum gives a human face to this often caustic debate--and an all-but-human face to the subjects of the struggle, the chimpanzees and monkeys themselves. Blum criss-crosses America to show us first hand the issues and personalities involved. She offers a wide-ranging, informative look at animal rights activists, now numbering some twelve million, from the moderate Animal Welfare Institute to the highly radical Animal Liberation Front (a group destructive enough to be placed on the FBI's terrorist list). And she interviews a wide variety of researchers, many forced to conduct their work protected by barbed wire and alarm systems, men and women for whom death threats and hate mail are common. She takes us to Roger Fouts's research center in Ellensburg, Washington, where we meet five chimpanzees trained in human sign language, and we visit LEMSIP, a research facility in New York State that has no barbed wire, no alarms--and no protesters chanting outside--because its director, Jan Moor-Jankowski, listens to activists with respect and treats his animals humanely. And along the way, Blum offers us insights into the many side-issues involved: the intense battle to win over school kids fought by both sides, and the danger of transplanting animal organs into humans. As it stands now, Blum concludes, the research community and its activist critics are like two different nations, nations locked in a long, bitter, seemingly intractable political standoff....But if you listen hard, there really are people on both sides willing to accept and work within the complex middle. When they can be freely heard, then we will have progressed to another place, beyond this time of hostilities. In The Monkey Wars, Deborah Blum gives these people their voice.

    Whatever it is, we call it matter or material substance. It is solid; it has mass. But what is matter, exactly? We are taught in school that matter is not continuous, but discrete. As a few of the philosophers of ancient Greece once speculated, nearly two and a half thousand years ago, matter comes in 'lumps', and science has relentlessly peeled away successive layers of matter to reveal its ultimate constituents.Surely, we can't keep doing this indefinitely. We imagine that we should eventually run up against some kind of ultimately fundamental, indivisible type of stuff, the building blocks from which everything in the Universe is made. The English physicist Paul Dirac called this 'the dream of philosophers'. But science has discovered that the foundations of our Universe are not as solid or as certain and dependable as we might have once imagined. They are instead built from ghosts and phantoms, of a peculiar quantum kind. And, at some point on this exciting journey of scientific discovery, we lost our grip on the reassuringly familiar concept of mass.How did this happen? How did the answers to our questions become so complicated and so difficult to comprehend? In Mass Jim Baggott explains how we come to find ourselves here, confronted by a very different understanding of the nature of matter, the origin of mass, and its implications for our understanding of the material world. Ranging from the Greek philosophers Leucippus and Democritus, and their theories of atoms and void, to the development of quantum field theory and the discovery of a Higgs boson-like particle, he explores our changing understanding of the nature of matter, and the fundamental related concept of mass.

    Administered off-label in small daily doses (0.5 to 4.5 mg), this generic drug is extremely affordable and presents few known side effects. So why has it languished in relative medical obscurity? The LDN Book explains the drug’s origins, its primary mechanism, and the latest research from practicing physicians and pharmacists as compiled by Linda Elsegood of The LDN Research Trust, the world’s largest LDN charity organization with over 19,000 members worldwide. Featuring ten chapters contributed by medical professionals on LDN’s efficacy and two patient-friendly appendices, The LDN Book is a comprehensive resource for doctors, pharmacists, and patients who want to learn more about how LDN is helping people now, and a clarion call for further research that could help millions more.

    You discover how fundamental principles and concepts relate to everyday life. Plus, you get plenty of study tips to improve your grades and score higher on exams! Explore the world of the cell — take a tour inside the structure and function of cells and see how viruses attack and destroy them Understand the stuff of life (molecules) — get up to speed on the structure of atoms, types of bonds, carbohydrates, proteins, DNA, RNA, and lipids Watch as cells function and reproduce — see how cells communicate, obtain matter and energy, and copy themselves for growth, repair, and reproduction Make sense of genetics — learn how parental cells organize their DNA during sexual reproduction and how scientists can predict inheritance patterns Decode a cell's underlying programming — examine how DNA is read by cells, how it determines the traits of organisms, and how it's regulated by the cell Harness the power of DNA — discover how scientists use molecular biology to explore genomes and solve current world problems Open the book and find: Easy-to-follow explanations of key topics The life of a cell — what it needs to survive and reproduce Why molecules are so vital to cells Rules that govern cell behavior Laws of thermodynamics and cellular work The principles of Mendelian genetics Useful Web sites Important events in the development of DNA technology Ten great ways to improve your biology grade

    Shapiro's Evolution: A View from the 21st Century proposes an important new paradigm for understanding biological evolution. Shapiro demonstrates why traditional views of evolution are inadequate to explain the latest evidence, and presents a compelling alternative. His information- and systems-based approach integrates advances in symbiogenesis, epigenetics, and mobile genetic elements, and points toward an emerging synthesis of physical, information, and biological sciences.

    Quality of life has improved dramatically in the last few decades alone, and the future is bright. But students must not forget that God provided humans with minds and resources to bring about these advances.A biblical perspective of healing and the use of medicine provides the best foundation for treating diseases and injury. In Exploring the World of Medicine, author John Hudson Tiner reveals the spectacular discoveries that started with men and women who used their abilities to better mankind and give glory to God.The fascinating history of medicine comes alive in this book, providing students with a healthy dose of facts, mini-biographies, and vintage illustrations. Includes chapter tests and index.

    As decomposers, they are critical to the formation and sustenance of soils and ecosystems. As endlessly innovative chemists, they devise and secrete enzymes that can break down a vast variety of materials, mitigate bacterial and viral infections, and interact―for better or worse―with the bodies and brains of animals that consume their fruiting bodies, commonly called mushrooms.Given their ubiquity and utility, it’s no surprise that humans have deep cultural connections to fungi and mushrooms, even while they have remained both understudied by institutional science and misunderstood by the general populace. But an emerging mycological vanguard is reaching maturity, exploring and advocating for fungi’s capacity to remediate contaminated landscapes and waterways, provide food and medicine, and demonstrate how humans might live in equitable and sustainable accord with nature and one another. This diverse cadre of growers, independent researchers, ecologists, entrepreneurs, and amateur enthusiasts is also scrambling to seize on rising demand for specialty mushrooms in culinary and medicinal markets, advance burgeoning fields of ‘applied mycology,’ and center conversations about social justice and sustainability.In In Search of Mycotopia, Doug Bierend introduces readers to an incredible and oft-overlooked kingdom of life and the potential it holds for our future, by way of the weird and wonderful communities of citizen scientists and microbe devotees working on the fungal frontier. Together they form a picture of the modern mycological movement, which sees these organisms as teachers, partners, and sources of wisdom that offer ways and means for creating a better world.

    This time physicist Robert Gilmore takes us on a journey with Dorothy, following the yellow building block road through the land of the Wizard of Quarks. Using characters and situations based on the Wizard of Oz story, we learn along the way about the fascinating world of particle physics. Classes of particles, from quarks to leptons are shown in an atomic garden, where atoms and molecules are produced. See how Dorothy, The Tin Geek, and the Cowardly Lion experience the bizarre world of subatomic particles.

    Perfect awareness. True beauty. Yoga is much more than just a physical activity. It is a conscious lifestyle that brings about a profound spiritual and personal transformation. This book on yoga invites you to experience yoga as the ancient masters intended it--a holistic way of life that unites the body, mind, and spirit for complete health and well-being.With clear instruction, Dr. Robert Butera guides you through ten steps on the path of yoga that are based on traditional yogic principles and practices, yet designed to fit seamlessly into your life. Yoga enthusiasts of all kinds will discover effective tools for creating a life of healthful beauty and inner peace.Understand the role of physical poses within the larger, holistic system of yoga Practice breathing techniques (pranayama), work with your energy centers (chakras), and develop your concentration Overcome psychological blocks, balance your emotions, and grow emotionally and spiritually Visit www.pureheartofyoga.com for free video clips of demonstrated yoga postures.Praise: "The Pure Heart of Yoga will bring increased depth to your yoga practice...It is an excellent book: thoughtful, reflective, deep, and accessible."--Eleanor Criswell, Ed.D., author of How Yoga Works"That he's able to instruct and inspire with a warm heart and skillful direction, without judgment or prejudice about the "style" or your yoga of choice, is good reason to believe this book will bring life to your practice."--Yoga Journal

    The world you live in is stranger than fiction... as you read this, you exist in other places at the same time. Do not regret having missed the chance to realize your dreams, for you may just have fulfilled it in another universe.. * Are the trillions of atoms that make you, nothing but vibrations in 10 dimensions?* Is it true that we are all connected with each other?* Can you go into the future to change the present?* Why do scientists and philosophers struggle with the concept of Time?* Can science explain consciousness through physics?* Is our fate driven by the underlying randomness in nature?* Is nature hiding the best-kept secrets which can never be unravelled by humans?The Speed of Time approaches the most complex and esoteric theories of science in lucid, clear and simple language and in the style of a thriller, leaving you wanting more... while addressing questions through the enigmatic theories in Physics such as Quantum Mechanics, Einstein's Theory of Relativity, Time, Chaos, and much more. Just start reading and you will not put it down.

    In The Horse, the journalist and equestrienne Wendy Williams brings that story brilliantly to life.Williams chronicles the 56-million-year journey of horses as she visits with horse experts around the world, revealing what our biological affinities and differences can tell us about the bond between horses and humans, and what our noble companion may think and feel. Indeed, recent scientific breakthroughs regarding the social and cognitive capacities of the horse and its ability to adapt to changing ecosystems indicate that this animal is a major evolutionary triumph.Williams charts the course that leads to our modern Equus-from the protohorse to the Dutch warmbloods, thoroughbreds, and miniature horses of the twenty-first century. She observes magnificent ancient cave art that signals a deep respect and admiration for horses well before they were domesticated, visits the mountains of Wyoming with an expert in equine behavior to understand the dynamics of free-roaming mustangs, witnesses the fluid gracefulness of the famous Lipizzaners of Vienna, contemplates what life is like for the sure-footed, mustachioed Garrano horses who thrive on the rugged terrain of Galicia, celebrates the Takhi horses of Mongolia, and more. She blends profound scientific insights with remarkable stories to create a unique biography of the horse as a sentient being with a fascinating past and a finely nuanced mind.The Horse is a revelatory account of the animal who has been at our side through the ages, carrying us into battle and traveling with us across the plains. Enriched by Wendy Williams's own experience with horses, The Horse is a masterful work of narrative nonfiction that pays tribute to this champion of the natural world.

    A concise atlas of anatomy, it contains more than 200 specially prepared accurate and clear drawings that include material never illustrated before. The text is as informative as the drawings; written at a level appropriate to undergraduate students and to bird lovers in general, it discusses why birds look and act the way they do.Designed to supplement a basic ornithology textbook, the Manual of Ornithology covers systematics and evolution, topography, feathers and flight, the skeleton and musculature, and the digestive, circulatory, respiratory, excretory, reproductive, sensory, and nervous systems of birds, as well as field techniques for watching and studying birds. Each chapter concludes with a list of key references for the topic covered, with a comprehensive bibliography at the end of the volume. The book will be a guide and reference for every level of bird study—a basic tool for investigation for anyone curious about the fascinating world of birds.