The Allies won the war with it. It conquered diseases, changed laws, and single-handedly launched the era of antibiotics. This incredible discovery was sulfa, the first antibiotic. In The Demon Under the Microscope, Thomas Hager chronicles the dramatic history of the drug that shaped modern medicine.Sulfa saved millions of lives—among them those of Winston Churchill and Franklin Delano Roosevelt Jr.—but its real effects are even more far reaching. Sulfa changed the way new drugs were developed, approved, and sold; transformed the way doctors treated patients; and ushered in the era of modern medicine. The very concept that chemicals created in a lab could cure disease revolutionized medicine, taking it from the treatment of symptoms and discomfort to the eradication of the root cause of illness. A strange and colorful story, The Demon Under the Microscope illuminates the vivid characters, corporate strategy, individual idealism, careful planning, lucky breaks, cynicism, heroism, greed, hard work, and the central (though mistaken) idea that brought sulfa to the world. This is a fascinating scientific tale with all the excitement and intrigue of a great suspense novel. For thousands of years, humans had sought medicines with which they could defeat contagion, and they had slowly, painstakingly, won a few battles: some vaccines to ward off disease, a handful of antitoxins. A drug or two was available that could stop parasitic diseases once they hit, tropical maladies like malaria and sleeping sickness. But the great killers of Europe, North America, and most of Asia—pneumonia, plague, tuberculosis, diphtheria, cholera, meningitis—were caused not by parasites but by bacteria, much smaller, far different microorganisms. By 1931, nothing on earth could stop a bacterial infection once it started. . . .But all that was about to change. . . . —from The Demon Under the Microscope

    He gunned down forty-five people inside and around the Tower before he was killed by two Austin police officers. In addition to promoting the rise of S.W.A.T. teams to respond to future crises, the murders spawned debates over issues which still plague America today: domestic violence, child abuse, drug abuse, military indoctrination, the insanity defense, and the delicate balance between civil liberties and public safety.

    In Germs, three veteran reporters draw on top sources inside and outside the U.S. government to lay bare Washington's secret strategies for combating this deadly threat.Featuring an inside look at how germ warfare has been waged throughout history and what form its future might take (and in whose hands), Germs reads like a gripping detective story told by fascinating key figures: American and Soviet medical specialists who once made germ weapons but now fight their spread, FBI agents who track Islamic radicals, the Iraqis who built Saddam Hussein's secret arsenal, spies who travel the world collecting lethal microbes, and scientists who see ominous developments on the horizon. With clear scientific explanations and harrowing insights, Germs is a masterfully written—and timely—work of investigative journalism.

    Robert J. Darling organizes President Bush's trip to Florida on Sept. 10, 2001, he believes the next couple of days will be quiet. He has no idea that a war is about to begin. The next day, after terrorists crash airliners into the World Trade Center towers and the Pentagon, Maj. Darling rushes to the president's underground chamber at the White House. There, he takes on the task of liaison between the vice president, national security advisor and the Pentagon. He works directly with the National Command Authority, and he's in the room when Vice President Cheney orders two fighter jets to get airborne in order to shoot down United Flight 93. Throughout the attacks, Maj. Darling witnesses the unprecedented actions that leaders are taking to defend America. As Vice President Cheney, Secretary of State Condoleezza Rice, and others make decisions at a lightning pace with little or no deliberation, he's there to lend his support. Follow Darling's story as he becomes a Marine Corps aviator and rises through the ranks to play an incredible role in responding to a crisis that changed the world in 9-11-01: The White House: Twenty-Four Hours inside the President's Bunker.

    For this new edition, the book has been thoroughly revised and updated and includes an entirely new chapter on environmental history.Peter Burke is joined here by a distinguished group of internationally renowned historians, including Robert Darnton, Ivan Gaskell, Richard Grove, Giovanni Levi, Roy Porter, Gwyn Prins, Joan Scott, Jim Sharpe, Richard Tuck, and Henk Wesseling. The contributions examine a wide range of interdisciplinary areas of historical research, including women's history, history from below, the history of reading, oral history, the history of the body, microhistory, the history of events, the history of images, and political history.

    Most animal rights theory focuses on the intrinsic capacities or interests of animals, and the moral status and moral rights that these intrinsic characteristics give rise to. Zoopolis shifts the debate from the realmof moral theory and applied ethics to the realm of political theory, focusing on the relational obligations that arise from the varied ways that animals relate to human societies and institutions. Building on recent developments in the political theory of group-differentiated citizenship, Zoopolisintroduces us to the genuine political animal. It argues that different types of animals stand in different relationships to human political communities. Domesticated animals should be seen as full members of human-animal mixed communities, participating in the cooperative project of sharedcitizenship. Wilderness animals, by contrast, form their own sovereign communities entitled to protection against colonization, invasion, domination and other threats to self-determination. Liminal animals who are wild but live in the midst of human settlement (such as crows or raccoons) should beseen as denizens, resident of our societies, but not fully included in rights and responsibilities of citizenship. To all of these animals we owe respect for their basic inviolable rights. But we inevitably and appropriately have very different relations with them, with different types ofobligations. Humans and animals are inextricably bound in a complex web of relationships, and Zoopolis offers an original and profoundly affirmative vision of how to ground this complex web of relations on principles of justice and compassion.

    There have been other books on Dr Morell's cocktail of treatments for Hitler and Goering's reliance on drugs, but Ohler's book is the first to show how the entire Nazi regime was permeated with drugs - cocaine, heroin, morphine and methamphetamines, the last of these crucial to troops' resilience and partly explaining German victory in 1940. Ohler is explicit that drugs cannot explain Third Reich ideology, but their promiscuous use impaired and confused decision-making, with drastic effects on Hitler and his entourage, who, as the war turned against Germany, took refuge in ever more poorly understood cocktails of stimulants. This chemical euphoria changes how we should think about the Nazi high command and its ability to understand the situation it found itself in by 1944-45. As such Blitzed will force a wider reinterpretation of several key events during the Second World War.

    In a spirit of reconciliation, Crane proposes to paint a more accurate picture of religion for his fellow unbelievers." --James Ryerson, New York Times Book ReviewContemporary debate about religion seems to be going nowhere. Atheists persist with their arguments, many plausible and some unanswerable, but these make no impact on religious believers. Defenders of religion find atheists equally unwilling to cede ground. The Meaning of Belief offers a way out of this stalemate.An atheist himself, Tim Crane writes that there is a fundamental flaw with most atheists' basic approach: religion is not what they think it is. Atheists tend to treat religion as a kind of primitive cosmology, as the sort of explanation of the universe that science offers. They conclude that religious believers are irrational, superstitious, and bigoted. But this view of religion is almost entirely inaccurate. Crane offers an alternative account based on two ideas. The first is the idea of a religious impulse: the sense people have of something transcending the world of ordinary experience, even if it cannot be explicitly articulated. The second is the idea of identification: the fact that religion involves belonging to a specific social group and participating in practices that reinforce the bonds of belonging. Once these ideas are properly understood, the inadequacy of atheists' conventional conception of religion emerges.The Meaning of Belief does not assess the truth or falsehood of religion. Rather, it looks at the meaning of religious belief and offers a way of understanding it that both makes sense of current debate and also suggests what more intellectually responsible and practically effective attitudes atheists might take to the phenomenon of religion.

    However, scant attention has been paid to the two women who were closest to him: Renee Pelagie de Sade, his adoring wife, and his powerful mother-in-law, Madame de Montreuil.Francine du Plessix Gray draws on thousands of pages of letters exchanged by the married couple, few of which have been published before in English, to explore in the fullest historical and psychological detail what it was like to be married to one of the most maverick spirits of modern history. Gray brings to life two remarkable women and their complex relationship to Sade as they dedicated themselves to protecting him from the law, curbing his excesses, and ultimately confining him. With immediacy, irony, and verve, At Home with the Marquis de Sade also conjures up the extravagant hedonism and terror of late eighteenth-century France.

    But as the couple pored over the Unabomber's seventy-eight page manifesto, David couldn't rule out the possibility. It slowly became clear to them that Ted was likely responsible for mailing the seventeen bombs that killed three people, and injured many more. Wanting to prevent further violence, David made the agonizing decision to turn his brother in to the FBI.Every Last Tie is David's highly personal, and powerful, memoir of his family, as well as a meditation on the possibilities for reconciliation and maintaining family bonds. Seen through David's eyes, Ted was a brilliant, yet troubled, young mathematician, and a loving older brother. Their parents were supportive, and emphasized to their sons the importance of education and empathy. But as Ted grew older he became more and more withdrawn, his behavior became increasingly erratic, and he often sent angry letters to his family from his isolated cabin in rural Montana.During Ted's trial David worked hard to save Ted from the death penalty, and since then he has been a leading activist in the anti–death penalty movement. The book concludes with an afterword by psychiatry professor, and forensic psychiatrist, James L. Knoll IV, who discusses the current challenges facing the mental health system in the United States, as well as the link between mental illness and violence.

    North and South America, too, suffered turbulence. The distinguished historian Geoffrey Parker examines first-hand accounts of men and women throughout the world describing what they saw and suffered during a sequence of political, economic and social crises that stretched from 1618 to the 1680s. Parker also deploys scientific evidence concerning climate conditions of the period, and his use of ‘natural’ as well as ‘human’ archives transforms our understanding of the World Crisis. Changes in the prevailing weather patterns during the 1640s and 1650s – longer and harsher winters, and cooler and wetter summers – disrupted growing seasons, causing dearth, malnutrition, and disease, along with more deaths and fewer births. Some contemporaries estimated that one-third of the world died, and much of the surviving historical evidence supports their pessimism.Parker’s demonstration of the link between climate change and worldwide catastrophe 350 years ago stands as an extraordinary historical achievement.  And the contemporary implications of his study are equally important: are we at all prepared today for the catastrophes that climate change could bring tomorrow?

    . . it immerses the readers in the world of 1865.”—Anne Sarah Rubin, Journal of American History The news of Abraham Lincoln’s assassination on April 15, 1865, just days after Confederate surrender, astounded the war-weary nation. Massive crowds turned out for services and ceremonies. Countless expressions of grief and dismay were printed in newspapers and preached in sermons. Public responses to the assassination have been well chronicled, but this book is the first to delve into the personal and intimate responses of everyday people—northerners and southerners, soldiers and civilians, black people and white, men and women, rich and poor.   Through deep and thoughtful exploration of diaries, letters, and other personal writings penned during the spring and summer of 1865, Martha Hodes, one of our finest historians, captures the full range of reactions to the president’s death—far more diverse than public expressions would suggest. She tells a story of shock, glee, sorrow, anger, blame, and fear. “’Tis the saddest day in our history,” wrote a mournful man. It was “an electric shock to my soul,” wrote a woman who had escaped from slavery. “Glorious News!” a Lincoln enemy exulted. “Old Lincoln is dead, and I will kill the goddamned Negroes now,” an angry white southerner ranted. For the black soldiers of the Fifty-Fourth Massachusetts, it was all “too overwhelming, too lamentable, too distressing” to absorb.   There are many surprises in the story Hodes tells, not least the way in which even those utterly devastated by Lincoln’s demise easily interrupted their mourning rituals to attend to the most mundane aspects of everyday life. There is also the unexpected and unabated virulence of Lincoln’s northern critics, and the way Confederates simultaneously celebrated Lincoln’s death and instantly—on the very day he died—cast him as a fallen friend to the defeated white South.   Hodes brings to life a key moment of national uncertainty and confusion, when competing visions of America’s future proved irreconcilable and hopes for racial justice in the aftermath of the Civil War slipped from the nation’s grasp. Hodes masterfully brings the tragedy of Lincoln’s assassination alive in human terms—terms that continue to stagger and rivet us one hundred and fifty years after the event they so strikingly describe.

    Trump as darkly symptomatic of a deeper societal distress. Equally challenging and profound, Twlilight of American Sanity makes sense of our time and charts the way forward.It is comforting to see President Donald Trump as a crazy man, a one-off, an exception—not a reflection on us or our democracy. But in ways I never anticipated, his rise was absolutely predictable and a mirror on our soul. … What does it say about us, that we elected someone so manifestly unfit and unprepared to determine mankind’s future? Trump is a symptom of a world in distress, not its sole cause. Blaming him for all our troubles misses the deeper, underlying societal sickness that made possible his unlikely ascent. Calling Trump crazy allows us to avoid confronting the craziness in our society—if we want to get sane, we must first gain insight about ourselves. Simply put: Trump isn’t crazy, but our society is. – from TWILIGHT OF AMERICAN SANITYMore than three years in the making: the world's leading expert on psychiatric diagnosis, past leader of the American Psychiatric Association’s DSM (“the bible of psychology”), and author of the influential international bestseller on the medicalization of ordinary life, Saving Normal, draws upon his vast experience to deliver a powerful critique of modern American society’s collective slide away from sanity and offers an urgently needed prescription for reclaiming our bearings. Widely cited in recent months as the man who quite literally wrote the diagnostic criteria for narcissism, Allen Frances, M.D., has been at the center of the debate surrounding President Trump’s mental state—quoted in Evan Osnos’s May 2017 New Yorker article (“How Trump Could Get Fired”) and publishing a much-shared opinion letter in the New York Times (“An Eminent Psychiatrist Demurs on Trump’s Mental State”). Frances argues that Trump is "bad, not mad"--and that the real question to wrestle with is how we as a country could have chosen him as our leader. Twilight of American Sanity is an essential work for understanding our national crisis.

    She was arrested on the charge of witchcraft in June of 1663. She was found guilty and was executed on December 30th that same year. Her trial was long and involved, with many witnesses from several towns and villages.Consisting of direct translations of the trial testimony, The Trial of Tempel Anneke portrays a large and varied cast of characters including trades people, farmers, local nobility, village drunkards, and Tempel Anneke herself. Tempel Anneke was in several ways typical of those accused of witchcraft, yet from the testimony she emerges as a complex and controversial figure. She was literate and owned a few books and herbals; she prided herself on her medical and pharmaceutical knowledge and until the final stages of the trial when her confession was extracted under torture, she was sharp, assertive, and even witty in her responses to questioning. This English translation offers direct archival insight into the workings of 17th century law, contemporary understandings of justice, perceptions of natural and magical causes, and above all, the social history of the period.While other witchcraft materials exist, this is the only text available in English that allows students to follow a witchcraft trial from beginning to end. Highly readable, this astonishing narrative is perfectly suited to being read as a complete document. The useful additions of introduction, appendices, glossary, and index provide readers with important background information so that they can engage directly with the material.

    The furtive discovery of the dark continent of sex in banned magazines, the beauty of black ink on paper, but also the mysteries of space and the grief of mourning: these are some of the things we encounter as the philosopher takes us on a trip through the private theater of his mind, at the whim of his memories. Music, painting, politics, sex, and metaphysics: all contribute to making black more luminous than it has ever been.