This hard scifi novel, begins in the Arctic where an oil company is drilling and unwittingly discovers a megavirus which had been frozen in the permafrost for 30,000 years. It is a thousand times larger than any viruses known before and is a human pathogen. Now investigators must race against the ticking clock of the short Arctic summer to discover a way to protect workers from the virus before competitors drain the basin of its rich resources…and before anyone else dies from the hemorrhagic fever that the Laptev virus causes. (And now, Sarah Spallanzani's adventures continue in The Cobra Effect!)

    Henry Parsons, an unlikely but appealing hero, races to find the origins and cure of a mysterious new killer virus as it brings the world to its knees.At an internment camp in Indonesia, forty-seven people are pronounced dead with acute hemorrhagic fever. When Henry Parsons--microbiologist, epidemiologist--travels there on behalf of the World Health Organization to investigate, what he finds will soon have staggering repercussions across the globe: an infected man is on his way to join the millions of worshippers in the annual Hajj to Mecca. Now, Henry joins forces with a Saudi prince and doctor in an attempt to quarantine the entire host of pilgrims in the holy city... A Russian émigré, a woman who has risen to deputy director of U.S. Homeland Security, scrambles to mount a response to what may be an act of biowarfare... already-fraying global relations begin to snap, one by one, in the face of a pandemic... Henry's wife Jill and their children face diminishing odds of survival in Atlanta... and the disease slashes across the United States, dismantling institutions--scientific, religious, governmental--and decimating the population.

    It may be the start of a scientific experiment that could alter the human race forever--and reveal a shocking truth about our future.Experience the groundbreaking novel that will change everything you think you know about pandemics--and how to survive one.“Reads like a superior collaboration between Dan Brown and Michael Crichton.”—The GuardianNow an Amazon Charts and Wall Street Journal bestseller.A hundred miles north of Alaska, a US Coast Guard vessel discovers a sunken submarine at the bottom of the Arctic Ocean. It has no national identification and doesn’t match the records of any known vessel. Deep within, researchers find evidence of a scientific experiment that will rewrite our basic understanding of the human race.In Atlanta, Dr. Peyton Shaw is awakened by the phone call she has dreaded for years. As the CDC’s leading epidemiologist, she’s among the first responders to outbreaks around the world. It’s a lonely and dangerous job, but it’s her life—and she’s good at it. This time, she may have met her match.In Kenya, an Ebola-like pathogen has infected two Americans. One lies at death’s door. With the clock ticking, Peyton assembles her team and joins personnel from the Kenyan Ministry of Health and the WHO. What they find in the remote village is beyond their worst fears. As she traces the origin of the pathogen, Peyton begins to believe that there is more to this outbreak—that it may be merely the opening act in a conspiracy with far reaching consequences.In Berlin, Desmond Hughes awakens in a hotel room with no memory of how he got there or who he is. On the floor, he finds a dead security guard from an international pharmaceutical company. His only clue leads him to Peyton Shaw—a woman who seems to know him, but refuses to tell him how. With the police searching the city for him, Desmond desperately tries to piece together what happened to him. To his shock and horror, he learns that he may be involved in causing the outbreak—and could hold the only key to stopping it.As the pathogen spreads around the world, Peyton and Desmond race to unravel the conspiracy behind the pandemic—and uncover secrets some want to keep buried. With time running out, they face an unimaginable decision.Buy now and begin the journey (or read for free in Kindle Unlimited).Selected Praise and Published Reviews“I finished the book fast because I just couldn’t wait...”—WIRED GeekDad on Departure“Riddle makes an effort to keep the focus on how his characters react to each other (including to their future selves) rather than to the technological marvels that reshaped their world.”—Publisher’s Weekly on Departure“Well-constructed and tightly-wound as a fine Swiss watch—Departure has non-stop action, an engaging plot and, of course, wheels within wheels.”—Diana Gabaldon, #1 New York Times bestselling author of Outlander on Departure About Pandemic

    In The Demon in the Freezer, his first nonfiction book since The Hot Zone, a #1 New York Times bestseller, Richard Preston takes us into the heart of Usamriid, the United States Army Medical Research Institute of Infectious Diseases at Fort Detrick, Maryland, once the headquarters of the U.S. biological weapons program and now the epicenter of national biodefense.Peter Jahrling, the top scientist at Usamriid, a wry virologist who cut his teeth on Ebola, one of the world’s most lethal emerging viruses, has ORCON security clearance that gives him access to top secret information on bioweapons. His most urgent priority is to develop a drug that will take on smallpox-and win. Eradicated from the planet in 1979 in one of the great triumphs of modern science, the smallpox virus now resides, officially, in only two high-security freezers-at the Centers for Disease Control in Atlanta and in Siberia, at a Russian virology institute called Vector. But the demon in the freezer has been set loose. It is almost certain that illegal stocks are in the possession of hostile states, including Iraq and North Korea. Jahrling is haunted by the thought that biologists in secret labs are using genetic engineering to create a new superpox virus, a smallpox resistant to all vaccines.Usamriid went into a state of Delta Alert on September 11 and activated its emergency response teams when the first anthrax letters were opened in New York and Washington, D.C. Preston reports, in unprecedented detail, on the government’s response to the attacks and takes us into the ongoing FBI investigation. His story is based on interviews with top-level FBI agents and with Dr. Steven Hatfill.Jahrling is leading a team of scientists doing controversial experiments with live smallpox virus at CDC. Preston takes us into the lab where Jahrling is reawakening smallpox and explains, with cool and devastating precision, what may be at stake if his last bold experiment fails.

    She appears to be sleepwalking. She cannot talk and cannot be woken up. And she is heading with inexorable determination to a destination that only she knows. But Shana and her sister are not alone. Soon they are joined by a flock of sleepwalkers from across America, on the same mysterious journey. And like Shana, there are other "shepherds" who follow the flock to protect their friends and family on the long dark road ahead.For as the sleepwalking phenomenon awakens terror and violence in America, the real danger may not be the epidemic but the fear of it. With society collapsing all around them--and an ultraviolent militia threatening to exterminate them--the fate of the sleepwalkers depends on unraveling the mystery behind the epidemic. The terrifying secret will either tear the nation apart--or bring the survivors together to remake a shattered world.

    When implanted, the tapeworm protects us from illness, boosts our immune system - even secretes designer drugs. It's been successful beyond the scientists' wildest dreams. Now, years on, almost every human being has a SymboGen tapeworm living within them.But these parasites are getting restless. They want their own lives...and will do anything to get them.

    But when her otherwise healthy boyfriend, Carl, enters the hospital for routine surgery, her neatly ordered life is thrown into total chaos. Carl fails to return to consciousness after the procedure, and an MRI confirms brain death.Devastated by Carl’s condition, Lynn searches for answers. Convinced there’s more to the story than what the authorities are willing to reveal, Lynn uses all her resources at Mason-Dixon—including her initially reluctant lab partner, Michael Pender—to hunt down evidence of medical error or malpractice.What she uncovers, however, is far more disturbing. Hospitals associated with Middleton Healthcare, including the Mason-Dixon Medical Center, have unnervingly high rates of unexplained anesthetic complications and patients contracting serious and terminal illness in the wake of routine hospital admissions.When Lynn and Michael begin to receive death threats, they know they’re into something bigger than either of them anticipated. They soon enter a desperate race against time for answers before shadowy forces behind Middleton Healthcare and their partner, Sidereal Pharmaceuticals, can put a stop to their efforts once and for all.

    I live in the Pendleton as surely as I live everywhere. I am the Pendleton’s history and its destiny. The building is my place of conception, my monument, my killing ground. . . .The Pendleton stands on the summit of Shadow Hill at the highest point of an old heartland city, a Gilded Age palace built in the late 1800s as a tycoon’s dream home. Almost from the beginning, its grandeur has been scarred by episodes of madness, suicide, mass murder, and whispers of things far worse. But since its rechristening in the 1970s as a luxury apartment building, the Pendleton has been at peace. For its fortunate residents—among them a successful songwriter and her young son, a disgraced ex-senator, a widowed attorney, and a driven money manager—the Pendleton’s magnificent quarters are a sanctuary, its dark past all but forgotten.But now inexplicable shadows caper across walls, security cameras relay impossible images, phantom voices mutter in strange tongues, not-quite-human figures lurk in the basement, elevators plunge into unknown depths. With each passing hour, a terrifying certainty grows: Whatever drove the Pendleton’s past occupants to their unspeakable fates is at work again. Soon, all those within its boundaries will be engulfed by a dark tide from which few have escaped.Dean Koontz transcends all expectations as he takes readers on a gripping journey to a place where nightmare visions become real—and where a group of singular individuals hold the key to humanity’s destiny. Welcome to 77 Shadow Street.

    Secret Service agent Ethan Burke arrives in search of two missing federal agents, yet soon is facing much more than he bargained for. After a violent accident lands him in the hospital, Ethan comes to with no ID and no cell phone. The medical staff seems friendly enough, but sometimes feels...off. As days pass, Ethan's investigation into his colleagues' disappearance turns up more questions than answersWHY CAN'T HE MAKE CONTACT WITH HIS FAMILY IN THE OUTSIDE WORLD? WHY DOESN'T ANYONE BELIEVE HE IS WHO HE SAYS HE IS? AND WHAT'S THE PURPOSE OF THE ELECTRIFIED FENCES ENCIRCLING THE TOWN? ARE THEY KEEPING THE RESIDENTS IN? OR SOMETHING ELSE OUT?Each step toward the truth takes Ethan further from the world he knows, until he must face a horrifying fact—he may never get out of Wayward Pines alive.....

    Two years later, seventeen satellites are sent into the outer fringes of space to collect organisms and dust for study. One of them falls to earth, landing in a desolate area of Arizona. Twelve miles from the landing site, in the town of Piedmont, a shocking discovery is made: the streets are littered with the dead bodies of the town's inhabitants, as if they dropped dead in their tracks.--back cover

    Then people started dropping where they stood. Symptoms: Unthinkable It could kill in hours. There was no known cure, no vaccine, and the only antidote could kill millions. Diagnosis: Unstoppable. New York, Chicago and Florida are quarantined. International travel is halted. A Japanese doomsday cult commits mass suicide, its final mission accomplished. Physician Carol Mayer was the first person to alert the Center for Disease Control, but now, as the epidemic grows, she has one last hope for finding a vaccine. His name is Beck Casey, a former CIA expert on biological warfare. And the best potential sources for stopping this plague are the worst enemies from his past. Final Epidemic has begun.

    Just a bad dream, he thinks. She's had them before. Yet he can't help but worry when she cries out again as he pads down the hallway. Stepping through her doorway, he expects to find her sitting up in bed, frightened by a nightmare.But the nightmare is his. It's real. And it's just beginning...Something is burning Ash's daughter alive. Something horrible that is spreading beyond the walls of their home, and taking no prisoners.Thirty seconds later, Ash will discover his daughter isn't the only one in his family infected, and as his world spins, coming apart at the seams, a team of armed men in biohazard suits bursts into his house.But these aren't the good guys.They haven't come to save Ash's family. They've come to separate them, to finish what they started.The problem is Ash refuses to disappear. He wants only one thing: to find those responsible.Because humanity is on the brink of execution.And man is pulling the trigger.

    government facility unleashes the monstrous product of a chilling military experiment. Then, the unspeakable: a night of chaos and carnage gives way to sunrise on a nation, and ultimately a world, forever altered. All that remains for the stunned survivors is the long fight ahead and a future ruled by fear—of darkness, of death, of a fate far worse.As civilization swiftly crumbles into a primal landscape of predators and prey, two people flee in search of sanctuary. FBI agent Brad Wolgast is a good man haunted by what he's done in the line of duty. Six-year-old orphan Amy Harper Bellafonte is a refugee from the doomed scientific project that has triggered apocalypse. Wolgast is determined to protect her from the horror set loose by her captors, but for Amy, escaping the bloody fallout is only the beginning of a much longer odyssey—spanning miles and decades—toward the time an place where she must finish what should never have begun.With The Passage, award-winning author Justin Cronin has written both a relentlessly suspenseful adventure and an epic chronicle of human endurance in the face of unprecedented catastrophe and unimaginable danger. Its inventive storytelling, masterly prose, and depth of human insight mark it as a crucial and transcendent work of modern fiction.

    Working under the government’s shroud of secrecy, CIA operative Dew Phillips crisscrosses the country trying in vain to capture a live victim. With only decomposing corpses for clues, CDC epidemiologist Margaret Montoya races to analyze the science behind this deadly contagion. She discovers that these killers all have one thing in common – they’ve been contaminated by a bioengineered parasite, shaped by a complexity far beyond the limits of known science.Meanwhile Perry Dawsey – a hulking former football star now resigned to life as a cubicle-bound desk jockey – awakens one morning to find several mysterious welts growing on his body. Soon Perry finds himself acting and thinking strangely, hearing voices . . . he is infected. The fate of the human race may well depend on the bloody war Perry must wage with his own body, because the parasites want something from him, something that goes beyond mere murder.

    . . Deep in the jungles of Central America, an indigenous man discovers a unique and priceless treasure - a beautifully painted codex that has survived for centuries within the ruins of an undiscovered ancient Maya city. Knowing that this rare artifact could be worth millions, the looter smuggles it into the US - but unbeknownst to him, he has brought something far more dangerous across the border . . . In the first week of December 2012, the codex finds its way into the hands of the Antiquities Curator of the Getty Museum, Chel Manu, the world authority on ancient Mayan inscriptions. She is torn between her duty to alert the authorities and this once in a lifetime chance to translate the codex herself.Meanwhile - in an LA hospital, an unidentified man is dying of Fatal Insomnia, a rare and highly infectious neurological disease. The patient speaks only in a garbled Mayan dialect - and Chel Manu is called in to interpret his dying words . . . just as countless others in the city begin to show signs of infection. Within days the world seems to be unravelling, hurtling towards the prophesied apocalypse . . . and deciphering the codex is the only hope for humanity . . .