In this far-reaching narrative, Weisman explains how our massive infrastructure would collapse and finally vanish without human presence; which everyday items may become immortalized as fossils; how copper pipes and wiring would be crushed into mere seams of reddish rock; why some of our earliest buildings might be the last architecture left; and how plastic, bronze sculpture, radio waves, and some man-made molecules may be our most lasting gifts to the universe.The World Without Us reveals how, just days after humans disappear, floods in New York's subways would start eroding the city's foundations, and how, as the world's cities crumble, asphalt jungles would give way to real ones. It describes the distinct ways that organic and chemically treated farms would revert to wild, how billions more birds would flourish, and how cockroaches in unheated cities would perish without us. Drawing on the expertise of engineers, atmospheric scientists, art conservators, zoologists, oil refiners, marine biologists, astrophysicists, religious leaders from rabbis to the Dalai Lama, and paleontologists—who describe a prehuman world inhabited by megafauna like giant sloths that stood taller than mammoths—Weisman illustrates what the planet might be like today, if not for us.From places already devoid of humans (a last fragment of primeval European forest; the Korean DMZ; Chernobyl), Weisman reveals Earth's tremendous capacity for self-healing. As he shows which human devastations are indelible, and which examples of our highest art and culture would endure longest, Weisman's narrative ultimately drives toward a radical but persuasive solution that needn't depend on our demise. It is narrative nonfiction at its finest, and in posing an irresistible concept with both gravity and a highly readable touch, it looks deeply at our effects on the planet in a way that no other book has.

    This is Nick's story of his world record-breaking adventure and the extraordinary people who joined him along the way. On January 6th 2018, Nick Butter tied his laces and stepped out on to an icy pavement in Toronto, where he began to take the first steps of an epic journey that would see him run 196 marathons in every one of the world's 196 countries. Spending almost two years on the road and relying on the kindness of strangers to keep him moving, Nick's odyssey allowed him to travel slowly, on foot, immersing himself in the diverse cultures and customs of his host nations. Running through capital cities and deserts, around islands and through spectacular landscapes, Nick dodges bullets in Guinea-Bissau, crosses battlefields in Syria, survives a wild dog attack in Tunisia and runs around an erupting volcano in Guatemala. Along the way, he is often joined by local supporters and fellow runners, curious children and bemused passers-by. Telling their stories alongside his own, Nick captures the unique spirit of each place he visits and forges a new relationship with the world around him. Running the World captures Nick's journey as he sets three world records and covers over five thousand miles. As he recounts his adventures, he shares his unique perspective on our glorious planet, celebrates the diversity of human experience, and reflects on the overwhelming power of running.

    Just a half century ago, this idea was revolutionary. In April 1953, James Watson and Francis Crick published in Nature their groundbreaking work revealing the double helix structure of DNA. While this discovery received wide attention from both mainstream media and the academic community, it was just one part of the bigger story in this history of molecular biology. By the mid-1950s, the scientific community confirmed that genes were indeed comprised of DNA; they just needed to crack the genetic code—and the race was on. Life’s Greatest Secret is the full and rich history of this challenge and the characters—many of whom were not biologists—whose work contributed to this grand scientific endeavor: mathematician and father of cybernetics Norbert Wiener, physicist Erwin Schrödinger, information theorist Claude Shannon, and biologists Jacques Monod and Marshall Nirenberg.In Life’s Greatest Secret, science historian and zoologist Matthew Cobb shows that the race to crack the genetic code was mostly a matter of craft—individuals or small groups struggling with ideas and concepts as much as they were with facts, trying to find the right experiment to answer the right questions, even if they didn’t know what the questions were, and finding that, even when the most definitive answer served mostly to reveal more ignorance, whether in 1953, with Watson and Crick, or in 1961, when Nirenberg and Matthaei showed how DNA codes for specific amino acids, and again and again thereafter, or in 2000, with the first publication of a human genome. Each discovery was a leap forward in our understanding of the natural world and our place within in, akin to the discoveries of Galileo and Einstein in the realm of physics, or the publication of Darwin’s On the Origin of Species. And each served to show how much bigger the problem was that anyone had previously imagined, a trend that continues, as Cobb shows, even today, whether we are discussing gene regulation, epigenetics, or GMOs.Life’s Greatest Secret is a story of ideas and of experimentation, of ingenuity, insight, and dead-ends, in the hunt to make the greatest discovery of twentieth century biology. Ultimately, though, this is a story of humans exploring what it is that makes us human.

    In The Violinist's Thumb, he explores the wonders of the magical building block of life: DNA.There are genes to explain crazy cat ladies, why other people have no fingerprints, and why some people survive nuclear bombs. Genes illuminate everything from JFK's bronze skin (it wasn't a tan) to Einstein's genius. They prove that Neanderthals and humans bred thousands of years more recently than any of us would feel comfortable thinking. They can even allow some people, because of the exceptional flexibility of their thumbs and fingers, to become truly singular violinists. Kean's vibrant storytelling makes science entertaining, explaining human history and whimsy while showing how DNA will influence our species' future.

    Details from cell structure and genetics, to immunology and pathogenicity, to taxonomy and phylogeny are covered. Also, based on recent taxonomic advances in RNA analysis, a new organization also makes this the first text to be divided by the three cell domains--Bacteria, Archaea, and Eukaryotes.

    Contrary to conventional wisdom, our brains and bodies are hardwired to carry out an evolutionary mission that determines much of what we do, from life plans to everyday decisions. With an accessible tone and a healthy disregard for political correctness, this lively and eminently readable book popularizes the latest research in a cutting- edge field of study-one that turns much of what we thought we knew about human nature upside-down. Every time we fall in love, fight with our spouse, enjoy watching a favorite TV show, or feel scared--walking alone at night, we are in part behaving as a human animal with its own unique nature-a nature that essentially stopped evolving 10,000 years ago. Alan S. Miller and Satoshi Kanazawa re-examine some of the most popular and controversial topics of modern life-and shed a whole new light on why we do the things we do. Reader beware: You may never look at human nature the same way again.

    For the first time in history, the secrets of the living brain are being revealed by a battery of high tech brain scans devised by physicists. Now what was once solely the province of science fiction has become a startling reality. Recording memories, telepathy, videotaping our dreams, mind control, avatars, and telekinesis are not only possible; they already exist. The Future of the Mind gives us an authoritative and compelling look at the astonishing research being done in top laboratories around the world—all based on the latest advancements in neuroscience and physics. One day we might have a "smart pill" that can enhance our cognition; be able to upload our brain to a computer, neuron for neuron; send thoughts and emotions around the world on a "brain-net"; control computers and robots with our mind; push the very limits of immortality; and perhaps even send our consciousness across the universe. Dr. Kaku takes us on a grand tour of what the future might hold, giving us not only a solid sense of how the brain functions but also how these technologies will change our daily lives. He even presents a radically new way to think about "consciousness" and applies it to provide fresh insight into mental illness, artificial intelligence and alien consciousness. With Dr. Kaku's deep understanding of modern science and keen eye for future developments, The Future of the Mind is a scientific tour de force--an extraordinary, mind-boggling exploration of the frontiers of neuroscience.

    But how did Watson and Crick do it—and why were they the ones who succeeded?In truth, the discovery of DNA’s structure is the story of five towering minds in pursuit of the advancement of science, and for almost all of them, the prospect of fame and immortality: Watson, Crick, Rosalind Franklin, Maurice Wilkins, and Linus Pauling. Each was fascinating and brilliant, with strong personalities that often clashed. Howard Markel skillfully re-creates the intense intellectual journey, and fraught personal relationships, that ultimately led to a spectacular breakthrough. But it is Rosalind Franklin—fiercely determined, relentless, and an outsider at Cambridge and the University of London in the 1950s, as the lone Jewish woman among young male scientists—who becomes a focal point for Markel.The Secret of Life is a story of genius and perseverance, but also a saga of cronyism, misogyny, anti-Semitism, and misconduct. Drawing on voluminous archival research, including interviews with James Watson and with Franklin’s sister, Jenifer Glynn, Markel provides a fascinating look at how science is done, how reputations are undone, and how history is written, and revised.A vibrant evocation of Cambridge in the 1950s, Markel also provides colorful depictions of Watson and Crick—their competitiveness, idiosyncrasies, and youthful immaturity—and compelling portraits of Wilkins, Pauling, and most cogently, Rosalind Franklin. The Secret of Life is a lively and sweeping narrative of this landmark discovery, one that finally gives the woman at the center of this drama her due.

    It is also a lucid exposition of the nature and methods of genuine science. The book begins with a concise introduction to evolutionary theory for non-scientists and closes with a rebuttal of the charge that this theory undermines religious and moral values. It will astonish many readers that this case must still be made in the 1980s, but since it must, Philip Kitcher makes it irresistibly and forcefully.Not long ago, a federal court struck down an Arkansas law requiring that scientific Creationism be taught in high school science classes. Contemporary Creationists may have lost one legal battle, but their cause continues to thrive. Their efforts are directed not only at state legislatures but at local school boards and textbook publishers. As Kitcher argues in this rigorous but highly readable book, the integrity of science is under attack. The methods of inquiry used in evolutionary biology are those which are used throughout the sciences. Moreover, modern biology is intertwined with other fields of science--physics, chemistry, astronomy, and geology. Creationists hope to persuade the public that education in science should be torn apart to make room for a literal reading of Genesis.Abusing Science refutes the popular complaint that the scientific establishment is dogmatic and intolerant, denying academic freedom to the unorthodox. It examines Creationist claims seriously and systematically, one by one, showing clearly just why they are at best misguided, at worst ludicrous.

    He seized the opportunity to do something "noble." Using an electric saw, Harvey sliced through the skull and gingerly removed the organ that would both define and haunt the rest of his life. Harvey struck a controversial deal with Einstein's family to keep the brain, swearing to safeguard it from souvenir hunters and publicity seekers, and to make it available only for serious scientific inquiry. Not a neuroscientist himself, he became the unlikely custodian of this object of intense curiosity and speculation, and the self-styled bulwark against the relentless power of Einstein's growing celebrity. Bridging the post-war era and the new millennium, Possessing Genius is the first comprehensive account of the circuitous path the brain took with Harvey during the decades it remained in his possession. Harvey permitted Einstein's gray matter to be sliced, diced, probed, prodded, and weighed by those hoping to solve the enigma and locate the source of genius itself. The brain was more than a subject of scientific investigation, it was a kind of holy relic; the history of its adventures since 1955 reflects the vicissitudes and vanities underpinning what we believe makes us human. Abraham has gathered together all of the fascinating details and documents of the brain's saga--including previously unpublished correspondence between Harvey and Otto Nathan, the executor of Einstein's estate—and from them woven a story that is both deeply engrossing and highly illuminating.

    That scientist, David Hungerford, had no way of knowing that he had stumbled upon the starting point of modern cancer research—the Philadelphia chromosome. This book charts not only that landmark discovery, but also—for the first time, all in one place—the full sequence of scientific and medical discoveries that brought about the first-ever successful treatment of a lethal cancer at the genetic level.The significance of this mutant chromosome would take more than three decades to unravel; in 1990, it was recognized as the sole cause of a deadly blood cancer, chronic myeloid leukemia, or CML. This dramatic discovery launched a race involving doctors and researchers around the world, who recognized that in principle it might be possible to target CML at its genetic source.Science journalist Jessica Wapner brings extensive original reporting to this book, including interviews with more than thirty-five people with a direct role in this story. Wapner reconstructs more than forty years of crucial breakthroughs, clearly explains the science behind them, and pays tribute to the dozens of researchers, doctors, and patients whose curiosity and determination restored the promise of a future to the more than 70,000 people worldwide who are diagnosed with CML each year. Chief among them is researcher and oncologist Dr. Brian Druker, whose dedication to his patients fueled his quest to do everything within his power to save them.The Philadelphia Chromosome helps us to fully understand and appreciate just how pathbreaking, hard-won, and consequential are the achievements it recounts—and to understand the principles behind much of today’s most important cancer research, as doctors and scientists race to uncover and treat the genetic roots of a wide range of cancers.

    This clear, concise look at the basic principles and concepts of genetics uses a human genetics perspective to discuss the methods and experiments upon which genetic principles are based, such as DNA replication.

    In the mid-1970s, scientists began using DNA sequences to reexamine the history of all life. Perhaps the most startling discovery to come out of this new field—the study of life’s diversity and relatedness at the molecular level—is horizontal gene transfer (HGT), or the movement of genes across species lines. It turns out that HGT has been widespread and important. For instance, we now know that roughly eight percent of the human genome arrived not through traditional inheritance from directly ancestral forms, but sideways by viral infection—a type of HGT.David Quammen chronicles these discoveries through the lives of the researchers who made them—such as Carl Woese, the most important little-known biologist of the twentieth century; Lynn Margulis, the notorious maverick whose wild ideas about “mosaic” creatures proved to be true; and Tsutomu Wantanabe, who discovered that the scourge of antibiotic-resistant bacteria is a direct result of horizontal gene transfer, bringing the deep study of genome histories to bear on a global crisis in public health.

    But through our remarkable successes in acquiring knowledge we have learned how much we have yet to learn: the science we have, for example, addresses just 5% of the universe; pre-history is still being revealed, with thousands of historical sites yet to be explored; and the new neurosciences of mind and brain are just beginning. What do we know, and how do we know it? What do we now know that we don't know? And what have we learnt about the obstacles to knowing more? In a time of deepening battles over what knowledge and truth mean, these questions matter more than ever.Bestselling polymath and philosopher A. C. Grayling seeks to answer them in three crucial areas at the frontiers of knowledge: science, history, and psychology. In each area he illustrates how each field has advanced to where it is now, from the rise of technology to quantum theory, from the dawn of humanity to debates around national histories, from ancient ideas of the brain to modern theories of the mind.A remarkable history of science, life on earth, and the human mind itself, this is a compelling and fascinating tour de force, written with Grayling's verve, clarity and remarkable breadth of knowledge.

    She entered Ah-gwah-ching State Sanatorium at Walker, Minnesota, for what she thought would be a short stay. In January, her tuberculosis spread, and she nearly died. Her recovery required many months of bed rest and medical care.Marilyn loved to write, and the story of her three-year residency at the sanatorium is preserved in hundreds of letters that she mailed back home to her parents, who could visit her only occasionally and whom she missed terribly. The letters functioned as a diary in which Marilyn articulately and candidly recorded her reactions to roommates, medical treatments, Native American nurses, and boredom. She also offers readers the singular perspective of a bed-bound teenager, gossiping about boys, requesting pretty new pajamas, and enjoying Friday evening popcorn parties with other patients.Selections from this cache of letters are woven into an informative narrative that explores the practices and culture of a midcentury tuberculosis sanatorium and fills in long-forgotten details gleaned from recent conversations with Marilyn, who "graduated" from the sanatorium and went on to lead a full, productive life.