This book presents some of the most important modeling and prediction techniques, along with relevant applications. Topics include linear regression, classification, resampling methods, shrinkage approaches, tree- based methods, support vector machines, clustering, and more. Color graphics and real-world examples are used to illustrate the methods presented. Since the goal of this textbook is to facilitate the use of these statistical learning techniques by practitioners in science, industry, and other fields, each chapter contains a tutorial on implementing the analyses and methods presented in R, an extremely popular open source statistical software platform. Two of the authors co-wrote The Elements of Statistical Learning (Hastie, Tibshirani and Friedman, 2nd edition 2009), a popular reference book for statistics and machine learning researchers. An Introduction to Statistical Learning covers many of the same topics, but at a level accessible to a much broader audience. This book is targeted at statisticians and non-statisticians alike who wish to use cutting-edge statistical learning techniques to analyze their data. The text assumes only a previous course in linear regression and no knowledge of matrix algebra.

    Guy Leschziner's patients, there is no rest for the weary in mind and body. Insomnia, narcolepsy, night terrors, sleep apnea, and sleepwalking are just a sampling of conditions afflicting sufferers who cannot sleep--and their experiences in trying are the stuff of nightmares. Demoniac hallucinations frighten people into paralysis. Restless legs rock both the sleepless and their sleeping partners with unpredictable and uncontrollable kicking. Out-of-sync circadian rhythms confuse the natural body clock's days and nights.Then there are the extreme cases. A woman in a state of deep sleep who gets dressed, unlocks her car, and drives for several miles before returning to bed. The man who has spent decades cleaning out kitchens while "sleep-eating." The teenager prone to the serious, yet unfortunately nicknamed "Sleeping Beauty Syndrome" stuck in a cycle of excessive unconsciousness, binge eating, and uncharacteristic displays of aggression and hyper-sexuality while awake.With compassionate stories of his patients and their conditions, Dr. Leschziner illustrates the neuroscience behind our sleeping minds, revealing the many biological and psychological factors necessary in getting the rest that will not only maintain our physical and mental health, but improve our cognitive abilities and overall happiness.

    Translated into eight languages, it is an essential textbook, an accessible reference, and a bestselling text worldwide.This authoritative textbook retains the successful layout and approach of the bestselling fourth edition Four extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.Each chapter have been updated and expanded and the number of illustrations greatly increased.Over a third of the illustrations are new for this editionFour extra chapters have been added on dry eye, scleritis, corneal and refractive surgery, and systemic diseases.The contents of each chapter have been updated and expanded and the number of illustrations has significantly increased.

    This new edition of Elementary Korean, the most comprehensive and detailed introductory Korean textbook available, offers beginning learners of Korean everything they need to learn the language effectively. Perfect for a first-year university-level course use or the independent language learner. No prior knowledge of the language is necessary. The new format, now with dozens of illustrations, presents Korean vocabulary and Korean grammar in an accessible and understandable manner while extensive conversations and exercises help to reinforce the Korean language and build reading and listening comprehension. This edition includes:An MP3 audio CD and a dedicated website.Rich and highly nuanced examples with brand new illustrations.Detailed but on–technical grammar notes, ample writing exercises with an accompanying answer key.Detailed examples of authentic dialogue.Highly technical grammar notes.Plenty of writing practice.Dialogues, reading texts, and written exercises are in Hangul, the Korean alphabet, so students are quickly able to read and write authentic Korean. Layered lessons are designed to build on each other, making Korean easy to learn from the most popular introductory Korean language textbook available. Included is a revised audio CD that helps learners to speak like a native and a web-based practice component through the University of British Columbia that can help students to learn Korean even beyond the pages of this book. According to the Modern Language Association, enrollment in Korean in American universities is increasing rapidly. Available separately is the companion Elementary Korean Workbook. This helpful workbook will assist you in practicing and polishing your Korean language skills. Each lesson supplements the corresponding lesson in the textbook. There are ten activities per lesson, offering a range of exercises and practice opportunities to enable you to achieve proficiency in everyday, conversational Korean.

    It is designed as a reference for students in the physical sciences and engineering.

    Increased emphasis on gene activity, signal transduction and the emphasis on the roles of paracrine factors in development.

    It is the definitive reference guide, now in a second edition. Although the first edition was written in 1978, it continues to be a worldwide best-seller. This second edition brings the classic original up to date to include the ANSI standard. From the Preface: We have tried to retain the brevity of the first edition. C is not a big language, and it is not well served by a big book. We have improved the exposition of critical features, such as pointers, that are central to C programming. We have refined the original examples, and have added new examples in several chapters. For instance, the treatment of complicated declarations is augmented by programs that convert declarations into words and vice versa. As before, all examples have been tested directly from the text, which is in machine-readable form. As we said in the first preface to the first edition, C "wears well as one's experience with it grows." With a decade more experience, we still feel that way. We hope that this book will help you to learn C and use it well.

    By extracting the fundamental concepts from this enormous and ever-growing field, the authors tell the story of cell biology, and create a coherent framework through which non-expert readers may approach the subject. Written in clear and concise language, and beautifully illustrated, the book is enjoyable to read, and it provides a clear sense of the excitement of modern biology. Molecular Biology of the Cell sets forth the current understanding of cell biology (completely updated as of Autumn 2001), and it explores the intriguing implications and possibilities of the great deal that remains unknown. The hallmark features of previous editions continue in the Fourth Edition. The book is designed with a clean and open, single-column layout. The art program maintains a completely consistent format and style, and includes over 1,600 photographs, electron micrographs, and original drawings by the authors. Clear and concise concept headings introduce each section. Every chapter contains extensive references. Most important, every chapter has been subjected to a rigorous, collaborative revision process where, in addition to incorporating comments from expert reviewers, each co-author reads and reviews the other authors' prose. The result is a truly integrated work with a single authorial voice. Features : - Places the latest hot topics sensibly in context - including genomics, protein structure, array technology, stem cells and genetics diseases. - Incorporates and emphasises new genomic data. - All of molecular biology is brought together into one section (chapters 4-7) covering classically defined molecular biology and molecular genetics. - Two chapters deal exclusively with methods and contain information on the latest tools and techniques. - New chapters on "Pathogens, Infection, and Innate Immunity". - Cell Biology Interactive CD-ROM is packaged with every copy of the book. - Contains over 1,600 illustrations, electron micrographs and photographs, of which over 1,000 are originally conceived by the authors.

    Often they seem aloof, uncaring, and hurried. Of course, they’re not all like that, and most didn’t start out that way. Here are voices of third-year students just as they begin to take on clinical responsibilities. Their words focus on the odd transition students face when they must deal with real people in real time and in real crises and when they must learn to put aside their emotions to make quick, accurate, and sensitive decisions. Their decisions aren’t always right, and the consequences can be life-altering—for all involved. Moving, disturbing, and candid, their true stories show us a side of the profession that few ever see, or could even imagine. They show, often painfully, how medical students grow up, right at the bedside.

    In this book you will see how commonly performed operations can be found to be useless or even harmful when properly evaluated. That these claims come from an experienced, practicing orthopedic surgeon who performs many of these operations himself, makes the unsettling argument particularly compelling. Of course no surgeon is recommending invasive surgery in bad faith, but Ian Harris argues that the evidence for the success for many common operations, including knee arthroscopies, back fusion or cardiac stenting, become current accepted practice without full examination of the evidence.

    Stewart's Calculus is successful throughout the world because he explains the material in a way that makes sense to a wide variety of readers. His explanations make ideas come alive, and his problems challenge, to reveal the beauty of calculus. Stewart's examples stand out because they are not just models for problem solving or a means of demonstrating techniques--they also encourage readers to develp an analytic view of the subject. This edition includes new problems, examples, and projects.

    

    Janell Carroll clearly conveys foundational biological and health issues, extensively cites both current and classic research, and addresses all material in a fresh and fun way; her book helps teach students what they need, and want, to know about sexuality. Her focus takes into account the social, religious, ethnic, racial, and cultural contexts of today's students. Dr. Carroll has used feedback from the first edition to add even further value to this popular title-streamlining student pedagogy and providing dynamic learning opportunities through Active Summaries at the end of chapters, a new online student tutorial, new video components, and content for Classroom Response Systems. This continues to be the text most representative of today's students, incorporating new sexual position art, a new pronunciation guide, and (for instructors) a new cross-cultural Slang Guide.

    Although molecular topics are presented first, instructors can assign the chapters in any sequence. Pedagogical features such as chapter-opening “Key Questions” and strategically placed “Keynotes” help readers to efficiently master genetic concepts. The Genetics Place Companion Website contains interactive iActivities and narrated animations that help readers visualize and understand processes and concepts that are illustrated in the book. Genetics: An Introduction, DNA: The Genetic Material, DNA Replication, Gene Control of Proteins, Gene Expression: Transcription,Gene Expression: Translation, DNA Mutation, DNA Repair, and Transposable Elements, Structural Genomics, Functional and Comparative Genomics, Recombinant DNA Technology, Mendelian Genetics, Chromosomal Basis of Inheritance, Extensions of and Deviations from Mendelian Genetic Principles, Genetic Mapping in Eukaryotes, Genetics of Bacteria and Bacteriophages, Variations in Chromosome Structure and Number, Regulation of Gene Expression in Bacteria and Bacteriophages, Regulation of Gene Expression in Eukaryotes, Genetic Analysis of Development, Genetics of Cancer, Quantitative Genetics, Population Genetics, Molecular Evolution Intended for those interested in learning the basics of genetics

    The book also provides a balanced presentation of time-varying and static fields, preparingstudents for employment in today's industrial and manufacturing sectors. Streamlined to facilitate student understanding, this edition features worked examples in every chapter that explain how to use the theory presented in the text to solve different kinds of problems. Numerical methods, including MATLAB and vector analysis, are also included to help students analyzesituations that they are likely to encounter in industry practice. Elements of Electromagnetics, Fifth Edition, is designed for introductory undergraduate courses in electromagnetics.