As of 2004 an estimated 40 million people were living with the disease, and about 20 million had died. Despite rapid scientific advances there is still no cure and the drugs are expensive and toxic. In the developing world, especially in parts of Africa, life expectancy has plummeted to below 35 years, causing a serious decline in economic growth, a sharp increase in orphans, and the imminent collapse of health care systems. The news is not all bleak though. There have been unprecedented breakthroughs in understanding diseases and developing drugs. Because the disease is so closely linked to sexual activity and drug use, the need to understand and change behavior has caused us to reassess what it means to be human and how we should operate in the globalizing world. This Very Short Introduction tackles the science, the international and local politics, the fascinating demographics, and the devastating consequences of the disease, and suggests how we must respond.About the Series: Oxford's Very Short Introductions offers concise and original introductions to a wide range of subjects--from Islam to Sociology, Politics to Classics, and Literary Theory to History. Not simply a textbook of definitions, each volume provides trenchant and provocative--yet always balanced and complete--discussions of the central issues in a given topic. Every Very Short Introduction gives a readable evolution of the subject in question, demonstrating how it has developed and influenced society. Whatever the area of study, whatever the topic that fascinates the reader, the series has a handy and affordable guide that will likely prove indispensable.

    He discusses the social and political background of India in the Buddha's time and traces the development of his thought. He also assesses the rapid and widespread assimilation of Buddhism and its contemporary relevance. Well-paced and informative, this introduction will enlighten not only those who study Buddhism and comparative religion but anyone intrigued by the remarkable philosophy of one of the greatest religious thinkers.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    This book is a brief introduction to the political, social, religious, and cultural history of Anglo-Saxon England and it is the mostcomprehensive and authoritative short guide to the Anglo-Saxon age available.

    Is it in our genes? The structure of our brains? Our genome may determine our eye color and even aspects of our personality. But our friendships, failures, and passions also shape who we are. The question is: how?Sebastian Seung, a dynamic professor at MIT, is on a quest to discover the biological basis of identity. He believes it lies in the pattern of connections between the brain’s neurons, which change slowly over time as we learn and grow. The connectome, as it’s called, is where our genetic inheritance intersects with our life experience. It’s where nature meets nurture.Seung introduces us to the dedicated researchers who are mapping the brain’s connections, neuron by neuron, synapse by synapse. It is a monumental undertaking—the scientific equivalent of climbing Mount Everest—but if they succeed, it could reveal the basis of personality, intelligence, memory, and perhaps even mental disorders. Many scientists speculate that people with anorexia, autism, and schizophrenia are "wired differently," but nobody knows for sure. The brain’s wiring has never been clearly seen.In sparklingly clear prose, Seung reveals the amazing technological advances that will soon help us map connectomes. He also examines the evidence that these maps will someday allow humans to "upload" their minds into computers, achieving a kind of immortality.Connectome is a mind-bending adventure story, told with great passion and authority. It presents a daring scientific and technological vision for at last understanding what makes us who we are. Welcome to the future of neuroscience.

    More than twice the size of the United States, it was the great threat of the Cold War until it suddenly collapsed in 1991. Now, almost twenty years after the dissolution of this vast empire, what are we to make of its existence? Was it a heroic experiment, an unmitigated disaster, or a viable if flawed response to the modern world? Taking a fresh approach to the study of the Soviet Union, this Very Short Introduction blends political history with an investigation into Soviet society and culture from 1917 to 1991. Stephen Lovell examines aspects of patriotism, political violence, poverty, and ideology, and provides answers to some of the big questions about the Soviet experience. Throughout, the book takes a refreshing thematic approach to the history of the Soviet Union and it provides an up-to-date consideration of the Soviet Union's impact and what we have learnt since its end.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    However, their impact has not been limited to debates about geology and evolution: attempts to explain their existence has shaken religion at its very roots, and they have remained a subject of ceaseless fascination for people of all ages and backgrounds. In this readable and wide-ranging book, Keith Thomson provides a remarkably all-encompassing explanation of fossils as a phenomenon. How did Darwin use fossils to support his theory of evolution? What are living fossils? What fossils will we leave behind for future generations to examine? Beyond the scientific aspects, Thomson highlights the impact of fossils on philosophy and mythology, our concept of time, and today's popular culture. From the black market to the Piltdown Man, and from mythological dragons to living dinosaurs, fossils hold a permanent place in the popular imagination.

    What is communism? Where did the idea come from and what attracted people to it? Is there a future for communism? This Very Short Introduction considers these questions and more in the search to explore and understand this controversial political force.Explaining the theory behind its ideology, and examining the history and mindset behind its political, economic and social structures, Leslie Holmes considers the evolution of communism from Marx's time, to its practice in the Bolshevik Revolution, to its collapse in 1989-91. Holmes highlights theinner dynamics, crises, and demise of communism as a global system, and introduces the major players in the communist world, including Marx, Lenin, Stalin, and Mao.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundredsof key topics, from philosophy to Freud, quantum theory to Islam.

    The relics of their power, in traditions and behavior, in architecture and the arts, are still all around us. This engaging Very Short Introduction shows how ideas of aristocracy originated in ancient times, were transformed in the middle ages, and have only fallen apart over the last two centuries, following the outbreak of the American and French Revolutions. William Doyle, an authority on eighteen-century European history, here strips away the myths in which aristocracies have always sought to shroud themselves, but he also astutely delineates the true sources of their enduring power. Their outlook and behavior affected the rest of society in innumerable and sometimes surprising ways, but perhaps most surprising was the way in which the centuries-old aristocratic hegemony crumbled away. In this Very Short Introduction William Doyle considers why this happened and what is left today.

    Growing understanding of the immune system, and especially the creation of immune memory (long lasting protection), which can be harnessed in the design of vaccines, have been major breakthroughs in medicine.In this Very Short Introduction, Paul Klenerman describes the immune system, and how it works in health and disease. In particular he focuses on the human immune system, considering how it evolved, the basic rules that govern its behavior, and the major health threats where it is important. Theimmune system comprises a series of organs, cells and chemical messengers which work together as a team to provide defence against infection. Klenerman discusses these components, the critical signals that trigger them and how they exert their protective effects, including so-called innate immuneresponses, which react very fast to infection, and adaptive immune responses, which have huge diversity and a capacity to recognize and defend against a massive array of micro-organisms. Klenerman also considers what happens when our immune systems fail to be activated effectively, leading toserious infections, problems with inherited diseases, and also HIV/AIDS. At the opposite extreme, as Klenerman shows, an over-exaggerated immune response leads to inflammatory diseases such as Multiple Sclerosis and Rheumatoid Arthritis, as well as allergy and asthma. Finally he looks at the Immunesystem v2.o - how immune therapies and vaccines can be advanced to protect us against the major diseases of the 21st century.ABOUT THE SERIES: The Very Short Introductions series from Oxford University Press contains hundreds of titles in almost every subject area. These pocket-sized books are the perfect way to get ahead in a new subject quickly. Our expert authors combine facts, analysis, perspective, new ideas, andenthusiasm to make interesting and challenging topics highly readable.

    CBT illuminates the links between thoughts, emotions, behaviors, and physical health and uses those connections to develop concrete plans for self-improvement. Built on a solid foundation of neurological and behavioral research, CBT is an approach almost anyone can use for promoting greater mental health and improving quality of life. In 24 engaging half-hour lectures, you'll build a robust and effective self-improvement toolkit with the expert guidance of Professor Satterfield of the University of California, San Francisco. You will explore CBT's roots in Socratic and stoic philosophy, build a toolkit of CBT techniques, and hear about the latest research about its outcomes. Additionally this intriguing and practical course allows you to take on the role of medical student, physician, psychologist, and patient. Throughout the course you'll explore issues that cause people to seek out therapy. In some cases you'll get to hear Dr. Satterfield working with a patient, and in others you'll be delving into research to find what causes issues and how CBT helps to resolve them. Everyone has something about their life that they would like to improve. With the tools in CBT and the desire to make your situation better, you can create lasting change in your life.

    Travel fast enough and you could weigh as much as a jumbo jet, be flattened thinner than a CD without feeling a thing-and live forever! As for the angles of a triangle, they do not always have to add up to 180 degrees. And then, of course, there are black holes. These are but a few of the extraordinary consequences of Einstein's theory of relativity. It is now over a hundred years since he made these discoveries, and yet the general public is still largely unaware of them. Filled with illuminating anecdotes and fascinating accounts of experiments, this book aims to introduce the interested lay person to the subject of relativity in a way which is accessible and engaging and at the same time scientifically rigorous. With relatively few mathematical equations--nothing more complicated than the Pythagoras's Theorem--this VSI packs a lot time into very little space, and for anyone who has felt intimidated by Einstein's groundbreaking theory, it offers the perfect place to start. About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.

    Veterans and their families deal with the painful aftermath of combat; one in five Americans has been molested; one in four grew up with alcoholics; one in three couples have engaged in physical violence. Such experiences inevitably leave traces on minds, emotions, and even on biology. Sadly, trauma sufferers frequently pass on their stress to their partners and children. Renowned trauma expert Bessel van der Kolk has spent over three decades working with survivors. In The Body Keeps the Score, he transforms our understanding of traumatic stress, revealing how it literally rearranges the brain’s wiring—specifically areas dedicated to pleasure, engagement, control, and trust. He shows how these areas can be reactivated through innovative treatments including neurofeedback, mindfulness techniques, play, yoga, and other therapies. Based on Dr. van der Kolk’s own research and that of other leading specialists, The Body Keeps the Score offers proven alternatives to drugs and talk therapy—and a way to reclaim lives.

    From humble beginnings on the seven hills beside the Tiber, the city of Rome grew to dominate the ancient Mediterranean. Led by her senatorial aristocracy, Republican armies defeated Carthage and the successor kingdoms of Alexander the Great, and brought the surrounding peoples to east and west into the Roman sphere. In this Very Short Introduction, David M. Gwynn provides a fascinating introduction to the history of the Roman Republic, ranging from the origins of Rome and the vivid Roman legends that surround the foundations of the city, to the overthrow of the monarchy in 509 BC, the five hundred years of republican rule, the rise of Julius Caesar and Caesar Augustus, and the establishment of the Principate. Gwynn considers the political structure of the Republic, including its unique constitution, and he highlights literary and material sources, bringing to life the culture and society of Republican Rome. He also reflects on the Roman values and beliefs of the time, in order to shed light on the Republic's dramatic rise and fall. Finally, Gwynn reflects on the remarkable legacy of the Roman Republic, including its modern-day resonance and legacy in literature and in film, where it is often presented as a model, a source of inspiration, but also a warning.

    In this Very Short Introduction, engineer David Muir Wood turns a spotlight on a field that we often take for granted. He sheds light on the nature and importance of civil engineering in the history of civilization and urbanization, outlines its many accomplishments in the modern era, and points to the hurdles that civil engineering will face in the future. Beginning with the task of creating a settlement on a deserted island, Muir Wood sets out the problems that civil engineers face every day, highlighting the social and environmental challenges as well as the grasp of science and technology needed to craft buildings, bridges, tunnels, houses, and areas of recreation. The author also profiles the lives of some of the major civil engineers, such as Isambard Kingdom Brunel, the acclaimed builder of steamships, railways, and tunnels, and Sir Joseph Bazalgette, whose sewer system in central London was instrumental in relieving the city from cholera epidemics. Finally, Muir Wood considers the growing difficulty of managing our water and energy supplies, and he looks at the engineering profession's increased sensitivity to building and the environment.

    Politicians of all stripes stress its importance, as do church leaders, captains of industry and every kind of campaigning group--from those supporting global causes, such as tackling world poverty, to others with a largely local focus, such as combating neighborhood crime. In this brilliant, compact introduction, Richard Bellamy offers an eye-opening look at an idea that is as important as it is rare--the prospect of influencing government policy according to reasonably fair rules and on a more or less equal basis with others. Bringing together the most recent scholarship, the book sheds light on how ideas of citizenship have changed through time from ancient Greece to the present, looks at concepts such as membership and belonging, and highlights the relation between citizenship, rights, and democracy. Bellamy also examines the challenges confronting the very possibility of citizenship today, the impact of globalization, the desirability of "global citizenship," the teaching of citizenship in schools, citizenship tests for immigrants, and the many different definitions and types of citizenship in modern society.About the Series: Combining authority with wit, accessibility, and style, Very Short Introductions offer an introduction to some of life's most interesting topics. Written by experts for the newcomer, they demonstrate the finest contemporary thinking about the central problems and issues in hundreds of key topics, from philosophy to Freud, quantum theory to Islam.